280b969969e867984dcbbe84e72e999088a09844
ZC3H12A.md
| ... | ... | @@ -25,6 +25,8 @@ timeline |
| 25 | 25 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 26 | 26 | |
| 27 | 27 | [[include:DLBCL_ZC3H12A.md]] |
| 28 | +[[include:FL_ZC3H12A.md]] |
|
| 29 | + |
|
| 28 | 30 | |
| 29 | 31 | ## Mutation pattern and selective pressure estimates |
| 30 | 32 |
ZFP36L1.md
| ... | ... | @@ -29,20 +29,13 @@ timeline |
| 29 | 29 | |:------:|:----:|--------------------------------------| |
| 30 | 30 | ||2|relevance in MCL not firmly established| |
| 31 | 31 | ||1|high-confidence PMBL/cHL/GZL gene[@reichelFlowSortingExome2015]| |
| 32 | -| |2-a | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@paneaWholeGenomeLandscape2019]| |
|
| 33 | -| |1-a | aSHM target and high-confidence DLBCL gene [@morinFrequentMutationHistonemodifying2011]| |
|
| 32 | +| |2 | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@paneaWholeGenomeLandscape2019]| |
|
| 33 | +| |1 | aSHM target and high-confidence DLBCL gene [@morinFrequentMutationHistonemodifying2011]| |
|
| 34 | 34 | |
| 35 | 35 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 36 | 36 | |
| 37 | -|Entity|source |frequency (%)| |
|
| 38 | -|:------:|:---------------------:|:-------------:| |
|
| 39 | -|BL |GAMBL genomes+capture|2.08 | |
|
| 40 | -|BL |Thomas cohort |2.10 | |
|
| 41 | -|BL |Panea cohort |3.00 | |
|
| 42 | -|DLBCL |GAMBL genomes |6.69 | |
|
| 43 | -|DLBCL |Schmitz cohort |8.51 | |
|
| 44 | -|DLBCL |Reddy cohort |5.61 | |
|
| 45 | -|DLBCL |Chapuy cohort |8.12 | |
|
| 37 | +[[include:DLBCL_ZFP36L1.md]] |
|
| 38 | +[[include:BL_ZFP36L1.md]] |
|
| 46 | 39 | |
| 47 | 40 | ## Mutation pattern and selective pressure estimates |
| 48 | 41 |