HIST1H2AM.md
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@@ -23,24 +23,19 @@ This gene encodes the H2A protein, one of the core proteins comprising nucleosom
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## Mutation incidence in large patient cohorts (GAMBL reanalysis)
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-|Entity|source |frequency (%)|
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-|:------:|:---------------------:|:-------------:|
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-|DLBCL |GAMBL genomes |5.93 |
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-|DLBCL |Schmitz cohort |5.74 |
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-|DLBCL |Reddy cohort |4.80 |
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-|DLBCL |Chapuy cohort |5.98 |
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-|FL |GAMBL genomes |3.70 |
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-|BL |GAMBL genomes+capture|1.85 |
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-|BL |Thomas cohort |1.70 |
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-|BL |Panea cohort |3.00 |
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+### DLBCL
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+[[include:DLBCL_HIST1H2AM.md]]
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+
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+### BL
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+[[include:BL_HIST1H2AM.md]]
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+
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+### FL
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+[[include:FL_HIST1H2AM.md]]
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+
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## Mutation pattern and selective pressure estimates
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+[[include:dnds_HIST1H2AM.md]]
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-|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)|
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-|:------:|:----:|:---------------------:|:----------------:|:----------------:|
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-|DLBCL |No |No |1.844 |0 |
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-|FL |No |No |1.845 |0 |
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-|BL |No |No |2.149 |0 |
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## HIST1H2AM Hotspots
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