2df80920c3dd2691757e13b859ef631ee604a324
EEF1A1.md
| ... | ... | @@ -30,13 +30,8 @@ timeline |
| 30 | 30 | |
| 31 | 31 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 32 | 32 | |
| 33 | -|Entity|source |frequency (%)| |
|
| 34 | -|:------:|:--------------:|:-------------:| |
|
| 35 | -|DLBCL |GAMBL genomes | 4.78 | |
|
| 36 | -|DLBCL |Schmitz cohort| 2.98 | |
|
| 37 | -|DLBCL |Reddy cohort | 2.50 | |
|
| 38 | -|DLBCL |Chapuy cohort | 4.70 | |
|
| 39 | -|FL |GAMBL genomes |11.32 | |
|
| 33 | +[[include:DLBCL_EEF1A1.md]] |
|
| 34 | +[[include:FL_EEF1A1.md]] |
|
| 40 | 35 | |
| 41 | 36 | ## Mutation pattern and selective pressure estimates |
| 42 | 37 |
EP300.md
| ... | ... | @@ -31,21 +31,13 @@ timeline |
| 31 | 31 | |Entity|Tier|Description | |
| 32 | 32 | |:------:|:----:|--------------------------------------| |
| 33 | 33 | ||1|high-confidence MZL gene[@rossiCodingGenomeSplenic2012]| |
| 34 | -| |1-EE |high-confidence DLBCL gene supported by functional data [@pasqualucciInactivatingMutationsAcetyltransferase2011]| |
|
| 35 | -| |1-EE |high-confidence FL gene supported by functional data [@pasqualucciInactivatingMutationsAcetyltransferase2011]| |
|
| 34 | +| |1 |high-confidence DLBCL gene supported by functional data [@pasqualucciInactivatingMutationsAcetyltransferase2011]| |
|
| 35 | +| |1 |high-confidence FL gene supported by functional data [@pasqualucciInactivatingMutationsAcetyltransferase2011]| |
|
| 36 | 36 | |
| 37 | 37 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 38 | 38 | |
| 39 | -|Entity|source |frequency (%)| |
|
| 40 | -|:------:|:---------------------:|:-------------:| |
|
| 41 | -|BL |GAMBL genomes+capture| 4.62 | |
|
| 42 | -|BL |Thomas cohort | 4.20 | |
|
| 43 | -|BL |Panea cohort | 7.90 | |
|
| 44 | -|DLBCL |GAMBL genomes |11.85 | |
|
| 45 | -|DLBCL |Schmitz cohort | 9.79 | |
|
| 46 | -|DLBCL |Reddy cohort | 7.11 | |
|
| 47 | -|DLBCL |Chapuy cohort | 8.12 | |
|
| 48 | -|FL |GAMBL genomes |12.47 | |
|
| 39 | +[[include:DLBCL_EP300.md]] |
|
| 40 | +[[include:FL_EP300.md]] |
|
| 49 | 41 | |
| 50 | 42 | ## Mutation pattern and selective pressure estimates |
| 51 | 43 |
ETS1.md
| ... | ... | @@ -38,15 +38,8 @@ timeline |
| 38 | 38 | |
| 39 | 39 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 40 | 40 | |
| 41 | -|Entity|source |frequency (%)| |
|
| 42 | -|:------:|:---------------------:|:-------------:| |
|
| 43 | -|DLBCL |GAMBL genomes | 4.59 | |
|
| 44 | -|DLBCL |Schmitz cohort | 7.87 | |
|
| 45 | -|DLBCL |Reddy cohort | 4.40 | |
|
| 46 | -|DLBCL |Chapuy cohort | 5.56 | |
|
| 47 | -|BL |GAMBL genomes+capture| 7.62 | |
|
| 48 | -|BL |Thomas cohort | 7.60 | |
|
| 49 | -|BL |Panea cohort |11.90 | |
|
| 41 | +[[include:DLBCL_ETS1.md]] |
|
| 42 | +[[include:FL_ETS1.md]] |
|
| 50 | 43 | |
| 51 | 44 | ## Mutation pattern and selective pressure estimates |
| 52 | 45 |
ETV6.md
| ... | ... | @@ -34,12 +34,7 @@ timeline |
| 34 | 34 | |
| 35 | 35 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 36 | 36 | |
| 37 | -|Entity|source |frequency (%)| |
|
| 38 | -|:------:|:--------------:|:-------------:| |
|
| 39 | -|DLBCL |GAMBL genomes | 4.97 | |
|
| 40 | -|DLBCL |Schmitz cohort|10.43 | |
|
| 41 | -|DLBCL |Reddy cohort | 5.81 | |
|
| 42 | -|DLBCL |Chapuy cohort |10.26 | |
|
| 37 | +[[include:DLBCL_ETV6.md]] |
|
| 43 | 38 | |
| 44 | 39 | ## Mutation pattern and selective pressure estimates |
| 45 | 40 |
EZH2.md
| ... | ... | @@ -44,16 +44,9 @@ timeline |
| 44 | 44 | |
| 45 | 45 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 46 | 46 | |
| 47 | -|Entity|source |frequency (%)| |
|
| 48 | -|:------:|:---------------------:|:-------------:| |
|
| 49 | -|BL |GAMBL genomes+capture| 3.46 | |
|
| 50 | -|BL |Thomas cohort | 1.30 | |
|
| 51 | -|BL |Panea cohort |10.90 | |
|
| 52 | -|DLBCL |GAMBL genomes |13.77 | |
|
| 53 | -|DLBCL |Schmitz cohort | 9.15 | |
|
| 54 | -|DLBCL |Reddy cohort | 8.91 | |
|
| 55 | -|DLBCL |Chapuy cohort | 5.56 | |
|
| 56 | -|FL |GAMBL genomes |24.94 | |
|
| 47 | + |
|
| 48 | +[[include:DLBCL_EZH2.md]] |
|
| 49 | +[[include:FL_EZH2.md]] |
|
| 57 | 50 | |
| 58 | 51 | ## Mutation pattern and selective pressure estimates |
| 59 | 52 |