2e391dd32250dc3e1ecb0c786cca883bad7abddd
EZH2.md
| ... | ... | @@ -16,7 +16,7 @@ Although mutations in EZH2 have been described in some BL patients, they are ext |
| 16 | 16 | |
| 17 | 17 | ## Experimental Evidence |
| 18 | 18 | |
| 19 | -Mutations at the main hotspot and some less common hotspots lead to enhanced methylation by PRC2.[@yapSomaticMutationsEZH22011] |
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| 19 | +Mutations at the canonical hotspot (Y646) and some less common hotspots lead to enhanced histone H3 lysince 27 (H3K27) tri-methylation by PRC2.[@yapSomaticMutationsEZH22011] |
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| 20 | 20 | |
| 21 | 21 | ## Clinical Relevance |
| 22 | 22 |