EZH2.md
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## Experimental Evidence
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-Mutations at the main hotspot and some less common hotspots lead to enhanced methylation by PRC2.[@yapSomaticMutationsEZH22011]
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+Mutations at the canonical hotspot (Y646) and some less common hotspots lead to enhanced histone H3 lysince 27 (H3K27) tri-methylation by PRC2.[@yapSomaticMutationsEZH22011]
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## Clinical Relevance
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