2ef8272e698705f634c6866330d396c4386b96f8
HIST1H1C.md
| ... | ... | @@ -9,9 +9,11 @@ link-citations: true |
| 9 | 9 | |
| 10 | 10 | This is one of several genes that encode linker histone proteins that are recurrently mutated in DLBCL and FL.<sup>1,2</sup> Mutations are often found in the globular domain of the protein, which is critical for its interaction with DNA and other histone proteins. |
| 11 | 11 | |
| 12 | -## History |
|
| 13 | -Mutations in this gene were first described in DLBCL and FL in 2011 by Morin et al.<sup>1</sup> Mutations were subsequently reported in BL by Panea et al.<sup>3</sup> |
|
| 12 | +<<Warn("The variants reported in BL in this gene failed QC")>> |
|
| 13 | + |
|
| 14 | +**[See below ](#representative-mutations) or [the study page ](papers/paneaWholeGenomeLandscape2019.md#tier-2) for more information** |
|
| 14 | 15 | |
| 16 | +## History |
|
| 15 | 17 | |
| 16 | 18 | ```mermaid |
| 17 | 19 | %%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%% |
HIST1H2AG.md
| ... | ... | @@ -5,6 +5,10 @@ link-citations: true |
| 5 | 5 | --- |
| 6 | 6 | # HIST1H2AG |
| 7 | 7 | |
| 8 | +<<Warn("The variants reported in BL in this gene failed QC")>> |
|
| 9 | + |
|
| 10 | +**[See below ](#representative-mutations) or [the study page ](papers/paneaWholeGenomeLandscape2019.md#tier-2) for more information** |
|
| 11 | + |
|
| 8 | 12 | ## History |
| 9 | 13 | |
| 10 | 14 | ```mermaid |
| ... | ... | @@ -14,7 +18,7 @@ timeline |
| 14 | 18 | 2012-08-27 : Rossi : MZL |
| 15 | 19 | 2013-08-15 : Morin : DLBCL |
| 16 | 20 | 2017-01-26 : Krysiak : FL |
| 17 | - 2019-09-26 : Panea : BL |
|
| 21 | + 2019-09-26 : [Panea](papers/paneaWholeGenomeLandscape2019) : BL |
|
| 18 | 22 | ``` |
| 19 | 23 | |
| 20 | 24 | ## Relevance tier by entity |
| ... | ... | @@ -22,7 +26,7 @@ timeline |
| 22 | 26 | |Entity|Tier|Description | |
| 23 | 27 | |:------:|:----:|-----------------------------------------| |
| 24 | 28 | ||2|relevance in MZL not firmly established[@rossiCodingGenomeSplenic2012c]| |
| 25 | -| |2-F | Failed QC| |
|
| 29 | +| |2-F | Failed QC[@paneaWholeGenomeLandscape2019]| |
|
| 26 | 30 | | |2 |relevance in DLBCL not firmly established| |
| 27 | 31 | | |1 |high-confidence FL gene | |
| 28 | 32 |
HIST1H3I.md
| ... | ... | @@ -5,8 +5,6 @@ link-citations: true |
| 5 | 5 | --- |
| 6 | 6 | # HIST1H3I |
| 7 | 7 | |
| 8 | -<<Warn("The variants reported in this gene in BL failed QC")>> |
|
| 9 | - |
|
| 10 | 8 | ## History |
| 11 | 9 | ```mermaid |
| 12 | 10 | %%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%% |