321195a0437bbf6d6338d8739d8132840b49eec3
HIST1H2AC.md
| ... | ... | @@ -16,23 +16,18 @@ This gene encodes the H2A protein, one of the core proteins comprising nucleosom |
| 16 | 16 | |
| 17 | 17 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 18 | 18 | |
| 19 | -|Entity|source |frequency (%)| |
|
| 20 | -|:------:|:--------------:|:-------------:| |
|
| 21 | -|DLBCL |GAMBL genomes |5.16 | |
|
| 22 | -|DLBCL |Schmitz cohort|6.17 | |
|
| 23 | -|DLBCL |Reddy cohort |3.40 | |
|
| 24 | -|DLBCL |Chapuy cohort |6.41 | |
|
| 25 | -|FL |GAMBL genomes |2.31 | |
|
| 19 | +### DLBCL |
|
| 20 | +[[include:DLBCL_HIST1H2AC.md]] |
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| 26 | 21 | |
| 27 | -## Mutation pattern and selective pressure estimates |
|
| 22 | +### BL |
|
| 23 | +[[include:BL_HIST1H2AC.md]] |
|
| 28 | 24 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |1.742 | 0.000 | |
|
| 32 | -|DLBCL |No |No |3.090 |20.364 | |
|
| 33 | -|FL |No |No |1.715 | 0.000 | |
|
| 25 | +### FL |
|
| 26 | +[[include:FL_HIST1H2AC.md]] |
|
| 34 | 27 | |
| 35 | 28 | |
| 29 | +## Mutation pattern and selective pressure estimates |
|
| 30 | +[[include:dnds_HIST1H2AC.md]] |
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| 36 | 31 | |
| 37 | 32 | |
| 38 | 33 | ## HIST1H2AC Hotspots |