3353281edf940a94b0fdd1b83f7fdaa894868ee9
BIRC6.md
| ... | ... | @@ -7,22 +7,22 @@ BIRC6, as a negative regulator of non-canonical NF-κB signaling, is implicated |
| 7 | 7 | |
| 8 | 8 | |Entity|Tier|Description | |
| 9 | 9 | |:------:|:----:|--------------------------------------| |
| 10 | -|BL |2 |relevance in BL not firmly established| |
|
| 11 | 10 | |DLBCL |1 |high-confidence DLBCL gene | |
| 12 | 11 | |FL |1 |high-confidence FL gene | |
| 12 | +|BL |2 |relevance in BL not firmly established| |
|
| 13 | 13 | |
| 14 | 14 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 15 | 15 | |
| 16 | 16 | |Entity|source |frequency (%)| |
| 17 | 17 | |:------:|:---------------------:|:-------------:| |
| 18 | -|BL |GAMBL genomes+capture| 6.00 | |
|
| 19 | -|BL |Thomas cohort | 3.80 | |
|
| 20 | -|BL |Panea cohort |14.90 | |
|
| 21 | 18 | |DLBCL |GAMBL genomes | 7.27 | |
| 22 | 19 | |DLBCL |Schmitz cohort |10.00 | |
| 23 | 20 | |DLBCL |Reddy cohort | 6.41 | |
| 24 | 21 | |DLBCL |Chapuy cohort | 4.70 | |
| 25 | 22 | |FL |GAMBL genomes | 3.70 | |
| 23 | +|BL |GAMBL genomes+capture| 6.00 | |
|
| 24 | +|BL |Thomas cohort | 3.80 | |
|
| 25 | +|BL |Panea cohort |14.90 | |
|
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 |