3fb05c955117014291b3e2d3de8ded785ff5c6b1
morinlab.bib
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| 1 | +@article{weberPiggyBacTransposonTools2019, |
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| 2 | + title = {{{PiggyBac}} Transposon Tools for Recessive Screening Identify {{B-cell}} Lymphoma Drivers in Mice}, |
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| 3 | + author = {Weber, Julia and family=Rosa, given=Jorge, prefix=de la, useprefix=true and Grove, Carolyn S. and Schick, Markus and Rad, Lena and Baranov, Olga and Strong, Alexander and Pfaus, Anja and Friedrich, Mathias J. and Engleitner, Thomas and Lersch, Robert and Öllinger, Rupert and Grau, Michael and Menendez, Irene Gonzalez and Martella, Manuela and Kohlhofer, Ursula and Banerjee, Ruby and Turchaninova, Maria A. and Scherger, Anna and Hoffman, Gary J. and Hess, Julia and Kuhn, Laura B. and Ammon, Tim and Kim, Johnny and Schneider, Günter and Unger, Kristian and Zimber-Strobl, Ursula and Heikenwälder, Mathias and Schmidt-Supprian, Marc and Yang, Fengtang and Saur, Dieter and Liu, Pentao and Steiger, Katja and Chudakov, Dmitriy M. and Lenz, Georg and Quintanilla-Martinez, Leticia and Keller, Ulrich and Vassiliou, George S. and Cadiñanos, Juan and Bradley, Allan and Rad, Roland}, |
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| 4 | + date = {2019-03-29}, |
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| 5 | + journaltitle = {Nature Communications}, |
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| 6 | + shortjournal = {Nat Commun}, |
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| 7 | + volume = {10}, |
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| 8 | + number = {1}, |
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| 9 | + eprint = {30926791}, |
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| 10 | + eprinttype = {pmid}, |
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| 11 | + pages = {1415}, |
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| 12 | + issn = {2041-1723}, |
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| 13 | + doi = {10.1038/s41467-019-09180-3}, |
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| 14 | + abstract = {B-cell lymphoma (BCL) is the most common hematologic malignancy. While sequencing studies gave insights into BCL genetics, identification of non-mutated cancer genes remains challenging. Here, we describe PiggyBac transposon tools and mouse models for recessive screening and show their application to study clonal B-cell lymphomagenesis. In a genome-wide screen, we discover BCL genes related to diverse molecular processes, including signaling, transcriptional regulation, chromatin regulation, or RNA metabolism. Cross-species analyses show the efficiency of the screen to pinpoint human cancer drivers altered by non-genetic mechanisms, including clinically relevant genes dysregulated epigenetically, transcriptionally, or post-transcriptionally in human BCL. We also describe a CRISPR/Cas9-based in vivo platform for BCL functional genomics, and validate discovered genes, such as Rfx7, a transcription factor, and Phip, a chromatin regulator, which suppress lymphomagenesis in mice. Our study gives comprehensive insights into the molecular landscapes of BCL and underlines the power of genome-scale screening to inform biology.}, |
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| 15 | + langid = {english}, |
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| 16 | + pmcid = {PMC6440946}, |
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| 17 | + keywords = {Animals,Clone Cells,CRISPR-Cas Systems,DNA Transposable Elements,Gene Dosage,Gene Expression Regulation Neoplastic,Genes Neoplasm,Genes Tumor Suppressor,Genetic Association Studies,Genetic Testing,Humans,Loss of Heterozygosity,Lymphoma B-Cell,Mice Inbred C57BL,Mice Transgenic,Receptors Antigen B-Cell,Reproducibility of Results}, |
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| 18 | + file = {/Users/rmorin/Zotero/storage/3HPDTVR9/Weber et al. - 2019 - PiggyBac transposon tools for recessive screening .pdf} |
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| 19 | +} |
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| 20 | + |
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| 1 | 21 | @article{pinyolInactivationRB1Mantlecell2007, |
| 2 | 22 | title = {Inactivation of {{RB1}} in Mantle-Cell Lymphoma Detected by Nonsense-Mediated {{mRNA}} Decay Pathway Inhibition and Microarray Analysis}, |
| 3 | 23 | author = {Pinyol, Magda and Bea, Silvia and Plà, Laura and Ribrag, Vincent and Bosq, Jacques and Rosenwald, Andreas and Campo, Elias and Jares, Pedro}, |
| ... | ... | @@ -705,7 +725,7 @@ |
| 705 | 725 | keywords = {3T3 Cells,Animals,Autoimmune Lymphoproliferative Syndrome,B-Lymphocytes,Caspase 8,Cells Cultured,Chromosomal Instability,Down-Regulation,Genes p53,Genetic Predisposition to Disease,Lymphoma B-Cell,Mice,Mice Inbred C57BL,Mice Transgenic,Survival Analysis} |
| 706 | 726 | } |
| 707 | 727 | |
| 708 | -@article{venturuttiTBL1XR1MutationsDrive2020b, |
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| 728 | +@article{venturuttiTBL1XR1MutationsDrive2020, |
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| 709 | 729 | title = {{{TBL1XR1 Mutations Drive Extranodal Lymphoma}} by {{Inducing}} a {{Pro-tumorigenic Memory Fate}}}, |
| 710 | 730 | author = {Venturutti, Leandro and Teater, Matt and Zhai, Andrew and Chadburn, Amy and Babiker, Leena and Kim, Daleum and Béguelin, Wendy and Lee, Tak C. and Kim, Youngjun and Chin, Christopher R. and Yewdell, William T. and Raught, Brian and Phillip, Jude M. and Jiang, Yanwen and Staudt, Louis M. and Green, Michael R. and Chaudhuri, Jayanta and Elemento, Olivier and Farinha, Pedro and Weng, Andrew P. and Nissen, Michael D. and Steidl, Christian and Morin, Ryan D. and Scott, David W. and Privé, Gilbert G. and Melnick, Ari M.}, |
| 711 | 731 | date = {2020-07-23}, |
| ... | ... | @@ -724,7 +744,7 @@ |
| 724 | 744 | keywords = {ABC-DLBCL,Animals,BACH2,Basic-Leucine Zipper Transcription Factors,BCL6,cell fate,cell of origin,Chromatin,extranodal lymphoma,germinal center,Germinal Center,Histone Deacetylases,Humans,Immunologic Memory,Lymphoma Large B-Cell Diffuse,memory B cells,Mice,Mice Inbred C57BL,Mice Knockout,Mutagenesis Site-Directed,Nuclear Proteins,Nuclear Receptor Co-Repressor 2,Precursor Cells B-Lymphoid,Protein Binding,Proto-Oncogene Proteins c-bcl-6,Receptors Cytoplasmic and Nuclear,Repressor Proteins,RNA Interference,RNA Small Interfering,TBL1XR1,Transcription Genetic} |
| 725 | 745 | } |
| 726 | 746 | |
| 727 | -@article{huNovelMissenseM206K2013b, |
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| 747 | +@article{huNovelMissenseM206K2013, |
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| 728 | 748 | title = {A Novel Missense ({{M206K}}) {{STAT3}} Mutation in Diffuse Large {{B}} Cell Lymphoma Deregulates {{STAT3}} Signaling}, |
| 729 | 749 | author = {Hu, Guangzhen and Witzig, Thomas E. and Gupta, Mamta}, |
| 730 | 750 | date = {2013}, |