P2RY8.md
... ...
@@ -1,5 +1,5 @@
1 1
# P2RY8
2
-P2RY8 encodes a G protein–coupled receptor that is expressed on germinal center B cells. Signals through this receptor promote confinement of B cells to the GC niche.<sup>1</sup> Downstream signaling through Galpha13 (encoded by GNA13) and S1PR2 is distrupted by mutations of one of these genes in GC lymphomas including the GCB subgroup of DLBCL<sup>2</sup> and BL.
2
+P2RY8 encodes a G protein–coupled receptor that is expressed on germinal center B cells. Signals through this receptor promote confinement of B cells to the GC niche.<sup>1</sup> Downstream signaling through Galpha13 (encoded by GNA13) and S1PR2 is distrupted by mutations of one of these genes in GC lymphomas including the GCB subgroup of DLBCL<sup>2</sup> and BL.<sup>1</sup>
3 3
4 4
## Relevance tier by entity
5 5