4598117821e8b485c32964a076498c96d8699506
papers/loveGeneticLandscapeMutations2012.md
| ... | ... | @@ -42,7 +42,7 @@ All other BL studies, BL Tier 2, 101 |
| 42 | 42 | ### Tier 2 |
| 43 | 43 | |New gene|BL tier|Rating of reviewed variants| |
| 44 | 44 | |:-|:-:|:-:| |
| 45 | -|[ACAD9](../ACAD9)|2 || |
|
| 45 | +|[ACAD9](../ACAD9)|2 |★ ☆ ☆ ☆ ☆| |
|
| 46 | 46 | |[ACE](../ACE)|2 || |
| 47 | 47 | |[ATP2C2](../ATP2C2)|2 || |
| 48 | 48 | |[BCL6](../BCL6)|2 || |
| ... | ... | @@ -50,10 +50,10 @@ All other BL studies, BL Tier 2, 101 |
| 50 | 50 | |[BRD4](../BRD4)|2 || |
| 51 | 51 | |[BTG2](../BTG2)|2 || |
| 52 | 52 | |[C6orf27](../C6orf27)|2 || |
| 53 | -|[CAD](../CAD)|2 || |
|
| 53 | +|[CAD](../CAD)|2 |★ ☆ ☆ ☆ ☆| |
|
| 54 | 54 | |[CARD4](../CARD4)|2 || |
| 55 | 55 | |[CCT6B](../CCT6B)|2 || |
| 56 | -|[CDC73](../CDC73)|2 || |
|
| 56 | +|[CDC73](../CDC73)|2 |★ ★ ★ ☆ ☆| |
|
| 57 | 57 | |[CDH17](../CDH17)|2 || |
| 58 | 58 | |[COL4A2](../COL4A2)|2 || |
| 59 | 59 | |[CREBBP](../CREBBP)|2 || |
| ... | ... | @@ -77,13 +77,13 @@ All other BL studies, BL Tier 2, 101 |
| 77 | 77 | |[MAP3K6](../MAP3K6)|2 || |
| 78 | 78 | |[MYH10](../MYH10)|2 || |
| 79 | 79 | |[NBEAL1](../NBEAL1)|2 || |
| 80 | -|[NOTCH1](../NOTCH1)|2 || |
|
| 80 | +|[NOTCH1](../NOTCH1)|2 |★ ☆ ☆ ☆ ☆| |
|
| 81 | 81 | |[NRXN2](../NRXN2)|2 || |
| 82 | 82 | |[P2RY2](../P2RY2)|2 || |
| 83 | 83 | |[PC](../PC)|2 |★ ☆ ☆ ☆ ☆| |
| 84 | 84 | |[POLRMT](../POLRMT)|2 || |
| 85 | 85 | |[POR](../POR)|2 || |
| 86 | -|[PRSS22](../PRSS22)|2 || |
|
| 86 | +|[PRSS22](../PRSS22)|2 |★ ☆ ☆ ☆ ☆| |
|
| 87 | 87 | |[PTPRN](../PTPRN)|2 || |
| 88 | 88 | |[RANBP6](../RANBP6)|2 || |
| 89 | 89 | |[RBP3](../RBP3)|2 || |
papers/loveGeneticLandscapeMutations2012.pdf
papers/reddyGeneticFunctionalDrivers2017.pdf
papers/reddyGeneticFunctionalDrivers2017_tmp.html
| ... | ... | @@ -1,725 +0,0 @@ |
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| 368 | -<h1 id="reddygeneticfunctionaldrivers2017">@reddyGeneticFunctionalDrivers2017</h1> |
|
| 369 | -<h2 id="summary-of-novel-genes">Summary of novel genes</h2> |
|
| 370 | -<table> |
|
| 371 | -<thead> |
|
| 372 | -<tr> |
|
| 373 | -<th style="text-align:center">Entity</th> |
|
| 374 | -<th style="text-align:center">Tier 1 genes</th> |
|
| 375 | -<th style="text-align:center">Tier 2 genes</th> |
|
| 376 | -</tr> |
|
| 377 | -</thead> |
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| 378 | -<tbody> |
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| 379 | -<tr> |
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| 380 | -<td style="text-align:center">DLBCL</td> |
|
| 381 | -<td style="text-align:center">7</td> |
|
| 382 | -<td style="text-align:center">53</td> |
|
| 383 | -</tr> |
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| 386 | -<pre><code class="language-mermaid"><div class="mermaid">--- |
|
| 387 | -config: |
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| 388 | - sankey: |
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| 389 | - showValues: true |
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| 390 | - linkColor: target |
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| 391 | - width: 600 |
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| 392 | - height: 300 |
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| 393 | - nodeAlignment: right |
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| 394 | - prefix: '(' |
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| 395 | - suffix: ' genes)' |
|
| 396 | ---- |
|
| 397 | -sankey-beta |
|
| 398 | -This study, New Tier 1, 7 |
|
| 399 | -New Tier 1, DLBCL Tier 1, 7 |
|
| 400 | -This study, New Tier 2, 53 |
|
| 401 | -New Tier 2, DLBCL Tier 2, 53 |
|
| 402 | -All other DLBCL studies, DLBCL Tier 1, 121 |
|
| 403 | -All other DLBCL studies, DLBCL Tier 2, 145 |
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| 404 | -</div></code></pre> |
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| 405 | -<h2 id="novel-genes-reported-in-this-study">Novel genes reported in this study</h2> |
|
| 406 | -<h3 id="tier-1">Tier 1</h3> |
|
| 407 | -<table> |
|
| 408 | -<thead> |
|
| 409 | -<tr> |
|
| 410 | -<th style="text-align:left">New gene</th> |
|
| 411 | -<th style="text-align:center">DLBCL tier</th> |
|
| 412 | -</tr> |
|
| 413 | -</thead> |
|
| 414 | -<tbody> |
|
| 415 | -<tr> |
|
| 416 | -<td style="text-align:left"><a href="../ATM">ATM</a></td> |
|
| 417 | -<td style="text-align:center">1</td> |
|
| 418 | -</tr> |
|
| 419 | -<tr> |
|
| 420 | -<td style="text-align:left"><a href="../BIRC6">BIRC6</a></td> |
|
| 421 | -<td style="text-align:center">1</td> |
|
| 422 | -</tr> |
|
| 423 | -<tr> |
|
| 424 | -<td style="text-align:left"><a href="../HIST1H2BC">HIST1H2BC</a></td> |
|
| 425 | -<td style="text-align:center">1</td> |
|
| 426 | -</tr> |
|
| 427 | -<tr> |
|
| 428 | -<td style="text-align:left"><a href="../HNRNPU">HNRNPU</a></td> |
|
| 429 | -<td style="text-align:center">1</td> |
|
| 430 | -</tr> |
|
| 431 | -<tr> |
|
| 432 | -<td style="text-align:left"><a href="../SETD1B">SETD1B</a></td> |
|
| 433 | -<td style="text-align:center">1</td> |
|
| 434 | -</tr> |
|
| 435 | -<tr> |
|
| 436 | -<td style="text-align:left"><a href="../TOX">TOX</a></td> |
|
| 437 | -<td style="text-align:center">1</td> |
|
| 438 | -</tr> |
|
| 439 | -<tr> |
|
| 440 | -<td style="text-align:left"><a href="../UBE2A">UBE2A</a></td> |
|
| 441 | -<td style="text-align:center">1</td> |
|
| 442 | -</tr> |
|
| 443 | -</tbody> |
|
| 444 | -</table> |
|
| 445 | -<h3 id="tier-2">Tier 2</h3> |
|
| 446 | -<table> |
|
| 447 | -<thead> |
|
| 448 | -<tr> |
|
| 449 | -<th style="text-align:left">New gene</th> |
|
| 450 | -<th style="text-align:center">DLBCL tier</th> |
|
| 451 | -<th style="text-align:center">Rating of reviewed variants</th> |
|
| 452 | -</tr> |
|
| 453 | -</thead> |
|
| 454 | -<tbody> |
|
| 455 | -<tr> |
|
| 456 | -<td style="text-align:left"><a href="../ANKRD17">ANKRD17</a></td> |
|
| 457 | -<td style="text-align:center">2</td> |
|
| 458 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 459 | -</tr> |
|
| 460 | -<tr> |
|
| 461 | -<td style="text-align:left"><a href="../ARID1B">ARID1B</a></td> |
|
| 462 | -<td style="text-align:center">2</td> |
|
| 463 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 464 | -</tr> |
|
| 465 | -<tr> |
|
| 466 | -<td style="text-align:left"><a href="../ARID5B">ARID5B</a></td> |
|
| 467 | -<td style="text-align:center">2</td> |
|
| 468 | -<td style="text-align:center">★ ★ ★ ★ ☆</td> |
|
| 469 | -</tr> |
|
| 470 | -<tr> |
|
| 471 | -<td style="text-align:left"><a href="../ATR">ATR</a></td> |
|
| 472 | -<td style="text-align:center">2</td> |
|
| 473 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 474 | -</tr> |
|
| 475 | -<tr> |
|
| 476 | -<td style="text-align:left"><a href="../BRINP3">BRINP3</a></td> |
|
| 477 | -<td style="text-align:center">2</td> |
|
| 478 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 479 | -</tr> |
|
| 480 | -<tr> |
|
| 481 | -<td style="text-align:left"><a href="../BTBD3">BTBD3</a></td> |
|
| 482 | -<td style="text-align:center">2</td> |
|
| 483 | -<td style="text-align:center">★ ★ ★ ★ ☆</td> |
|
| 484 | -</tr> |
|
| 485 | -<tr> |
|
| 486 | -<td style="text-align:left"><a href="../CASP8">CASP8</a></td> |
|
| 487 | -<td style="text-align:center">2</td> |
|
| 488 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 489 | -</tr> |
|
| 490 | -<tr> |
|
| 491 | -<td style="text-align:left"><a href="../CBLB">CBLB</a></td> |
|
| 492 | -<td style="text-align:center">2</td> |
|
| 493 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 494 | -</tr> |
|
| 495 | -<tr> |
|
| 496 | -<td style="text-align:left"><a href="../CD22">CD22</a></td> |
|
| 497 | -<td style="text-align:center">2</td> |
|
| 498 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 499 | -</tr> |
|
| 500 | -<tr> |
|
| 501 | -<td style="text-align:left"><a href="../CDC73">CDC73</a></td> |
|
| 502 | -<td style="text-align:center">2</td> |
|
| 503 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 504 | -</tr> |
|
| 505 | -<tr> |
|
| 506 | -<td style="text-align:left"><a href="../CHD1">CHD1</a></td> |
|
| 507 | -<td style="text-align:center">2</td> |
|
| 508 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 509 | -</tr> |
|
| 510 | -<tr> |
|
| 511 | -<td style="text-align:left"><a href="../CHD8">CHD8</a></td> |
|
| 512 | -<td style="text-align:center">2</td> |
|
| 513 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 514 | -</tr> |
|
| 515 | -<tr> |
|
| 516 | -<td style="text-align:left"><a href="../CHST2">CHST2</a></td> |
|
| 517 | -<td style="text-align:center">2</td> |
|
| 518 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 519 | -</tr> |
|
| 520 | -<tr> |
|
| 521 | -<td style="text-align:left"><a href="../DCAF6">DCAF6</a></td> |
|
| 522 | -<td style="text-align:center">2</td> |
|
| 523 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 524 | -</tr> |
|
| 525 | -<tr> |
|
| 526 | -<td style="text-align:left"><a href="../DDX10">DDX10</a></td> |
|
| 527 | -<td style="text-align:center">2</td> |
|
| 528 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 529 | -</tr> |
|
| 530 | -<tr> |
|
| 531 | -<td style="text-align:left"><a href="../DICER1">DICER1</a></td> |
|
| 532 | -<td style="text-align:center">2</td> |
|
| 533 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 534 | -</tr> |
|
| 535 | -<tr> |
|
| 536 | -<td style="text-align:left"><a href="../DNMT3A">DNMT3A</a></td> |
|
| 537 | -<td style="text-align:center">2</td> |
|
| 538 | -<td style="text-align:center">★ ☆ ☆ ☆ ☆</td> |
|
| 539 | -</tr> |
|
| 540 | -<tr> |
|
| 541 | -<td style="text-align:left"><a href="../FOXP1">FOXP1</a></td> |
|
| 542 | -<td style="text-align:center">2</td> |
|
| 543 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 544 | -</tr> |
|
| 545 | -<tr> |
|
| 546 | -<td style="text-align:left"><a href="../FUBP1">FUBP1</a></td> |
|
| 547 | -<td style="text-align:center">2</td> |
|
| 548 | -<td style="text-align:center">★ ☆ ★ ☆ ☆</td> |
|
| 549 | -</tr> |
|
| 550 | -<tr> |
|
| 551 | -<td style="text-align:left"><a href="../GNAS">GNAS</a></td> |
|
| 552 | -<td style="text-align:center">2</td> |
|
| 553 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 554 | -</tr> |
|
| 555 | -<tr> |
|
| 556 | -<td style="text-align:left"><a href="../GOLGA5">GOLGA5</a></td> |
|
| 557 | -<td style="text-align:center">2</td> |
|
| 558 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 559 | -</tr> |
|
| 560 | -<tr> |
|
| 561 | -<td style="text-align:left"><a href="../HRAS">HRAS</a></td> |
|
| 562 | -<td style="text-align:center">2</td> |
|
| 563 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 564 | -</tr> |
|
| 565 | -<tr> |
|
| 566 | -<td style="text-align:left"><a href="../IKBKB">IKBKB</a></td> |
|
| 567 | -<td style="text-align:center">2</td> |
|
| 568 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 569 | -</tr> |
|
| 570 | -<tr> |
|
| 571 | -<td style="text-align:left"><a href="../JUNB">JUNB</a></td> |
|
| 572 | -<td style="text-align:center">2</td> |
|
| 573 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 574 | -</tr> |
|
| 575 | -<tr> |
|
| 576 | -<td style="text-align:left"><a href="../KCMF1">KCMF1</a></td> |
|
| 577 | -<td style="text-align:center">2</td> |
|
| 578 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 579 | -</tr> |
|
| 580 | -<tr> |
|
| 581 | -<td style="text-align:left"><a href="../LIN54">LIN54</a></td> |
|
| 582 | -<td style="text-align:center">2</td> |
|
| 583 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 584 | -</tr> |
|
| 585 | -<tr> |
|
| 586 | -<td style="text-align:left"><a href="../MAGT1">MAGT1</a></td> |
|
| 587 | -<td style="text-align:center">2</td> |
|
| 588 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 589 | -</tr> |
|
| 590 | -<tr> |
|
| 591 | -<td style="text-align:left"><a href="../MAP4K4">MAP4K4</a></td> |
|
| 592 | -<td style="text-align:center">2</td> |
|
| 593 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 594 | -</tr> |
|
| 595 | -<tr> |
|
| 596 | -<td style="text-align:left"><a href="../MARK1">MARK1</a></td> |
|
| 597 | -<td style="text-align:center">2</td> |
|
| 598 | -<td style="text-align:center">★ ☆ ☆ ☆ ☆</td> |
|
| 599 | -</tr> |
|
| 600 | -<tr> |
|
| 601 | -<td style="text-align:left"><a href="../MCL1">MCL1</a></td> |
|
| 602 | -<td style="text-align:center">2</td> |
|
| 603 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 604 | -</tr> |
|
| 605 | -<tr> |
|
| 606 | -<td style="text-align:left"><a href="../MECOM">MECOM</a></td> |
|
| 607 | -<td style="text-align:center">2</td> |
|
| 608 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 609 | -</tr> |
|
| 610 | -<tr> |
|
| 611 | -<td style="text-align:left"><a href="../MET">MET</a></td> |
|
| 612 | -<td style="text-align:center">2</td> |
|
| 613 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 614 | -</tr> |
|
| 615 | -<tr> |
|
| 616 | -<td style="text-align:left"><a href="../MSH2">MSH2</a></td> |
|
| 617 | -<td style="text-align:center">2</td> |
|
| 618 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 619 | -</tr> |
|
| 620 | -<tr> |
|
| 621 | -<td style="text-align:left"><a href="../MSH6">MSH6</a></td> |
|
| 622 | -<td style="text-align:center">2</td> |
|
| 623 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 624 | -</tr> |
|
| 625 | -<tr> |
|
| 626 | -<td style="text-align:left"><a href="../MYB">MYB</a></td> |
|
| 627 | -<td style="text-align:center">2</td> |
|
| 628 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 629 | -</tr> |
|
| 630 | -<tr> |
|
| 631 | -<td style="text-align:left"><a href="../NCOR1">NCOR1</a></td> |
|
| 632 | -<td style="text-align:center">2</td> |
|
| 633 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 634 | -</tr> |
|
| 635 | -<tr> |
|
| 636 | -<td style="text-align:left"><a href="../NF1">NF1</a></td> |
|
| 637 | -<td style="text-align:center">2</td> |
|
| 638 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 639 | -</tr> |
|
| 640 | -<tr> |
|
| 641 | -<td style="text-align:left"><a href="../NFKB2">NFKB2</a></td> |
|
| 642 | -<td style="text-align:center">2</td> |
|
| 643 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 644 | -</tr> |
|
| 645 | -<tr> |
|
| 646 | -<td style="text-align:left"><a href="../PHF6">PHF6</a></td> |
|
| 647 | -<td style="text-align:center">2</td> |
|
| 648 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 649 | -</tr> |
|
| 650 | -<tr> |
|
| 651 | -<td style="text-align:left"><a href="../PIK3CD">PIK3CD</a></td> |
|
| 652 | -<td style="text-align:center">2</td> |
|
| 653 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 654 | -</tr> |
|
| 655 | -<tr> |
|
| 656 | -<td style="text-align:left"><a href="../PTPN6">PTPN6</a></td> |
|
| 657 | -<td style="text-align:center">2</td> |
|
| 658 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 659 | -</tr> |
|
| 660 | -<tr> |
|
| 661 | -<td style="text-align:left"><a href="../PTPRK">PTPRK</a></td> |
|
| 662 | -<td style="text-align:center">2</td> |
|
| 663 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 664 | -</tr> |
|
| 665 | -<tr> |
|
| 666 | -<td style="text-align:left"><a href="../RARA">RARA</a></td> |
|
| 667 | -<td style="text-align:center">2</td> |
|
| 668 | -<td style="text-align:center">★ ☆ ☆ ☆ ☆</td> |
|
| 669 | -</tr> |
|
| 670 | -<tr> |
|
| 671 | -<td style="text-align:left"><a href="../RUNX1">RUNX1</a></td> |
|
| 672 | -<td style="text-align:center">2</td> |
|
| 673 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 674 | -</tr> |
|
| 675 | -<tr> |
|
| 676 | -<td style="text-align:left"><a href="../SETD5">SETD5</a></td> |
|
| 677 | -<td style="text-align:center">2</td> |
|
| 678 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 679 | -</tr> |
|
| 680 | -<tr> |
|
| 681 | -<td style="text-align:left"><a href="../SYK">SYK</a></td> |
|
| 682 | -<td style="text-align:center">2</td> |
|
| 683 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 684 | -</tr> |
|
| 685 | -<tr> |
|
| 686 | -<td style="text-align:left"><a href="../TGFBR2">TGFBR2</a></td> |
|
| 687 | -<td style="text-align:center">2</td> |
|
| 688 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 689 | -</tr> |
|
| 690 | -<tr> |
|
| 691 | -<td style="text-align:left"><a href="../TIPARP">TIPARP</a></td> |
|
| 692 | -<td style="text-align:center">2</td> |
|
| 693 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 694 | -</tr> |
|
| 695 | -<tr> |
|
| 696 | -<td style="text-align:left"><a href="../WAC">WAC</a></td> |
|
| 697 | -<td style="text-align:center">2</td> |
|
| 698 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 699 | -</tr> |
|
| 700 | -<tr> |
|
| 701 | -<td style="text-align:left"><a href="../YY1">YY1</a></td> |
|
| 702 | -<td style="text-align:center">2</td> |
|
| 703 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 704 | -</tr> |
|
| 705 | -<tr> |
|
| 706 | -<td style="text-align:left"><a href="../ZBTB7A">ZBTB7A</a></td> |
|
| 707 | -<td style="text-align:center">2</td> |
|
| 708 | -<td style="text-align:center">★ ☆ ☆ ☆ ☆</td> |
|
| 709 | -</tr> |
|
| 710 | -<tr> |
|
| 711 | -<td style="text-align:left"><a href="../ZFAT">ZFAT</a></td> |
|
| 712 | -<td style="text-align:center">2</td> |
|
| 713 | -<td style="text-align:center">★ ★ ☆ ☆ ☆</td> |
|
| 714 | -</tr> |
|
| 715 | -<tr> |
|
| 716 | -<td style="text-align:left"><a href="../ZFX">ZFX</a></td> |
|
| 717 | -<td style="text-align:center">2</td> |
|
| 718 | -<td style="text-align:center">★ ★ ★ ☆ ☆</td> |
|
| 719 | -</tr> |
|
| 720 | -</tbody> |
|
| 721 | -</table> |
|
| 722 | -<h1 id="details">Details</h1> |
|
| 723 | -
|
|
| 724 | -</body>
|
|
| 725 | -</html>
|