46e0827d06cd0a4b39183bca82afbe3b2149139d
LRRN3.md
| ... | ... | @@ -24,12 +24,7 @@ timeline |
| 24 | 24 | |
| 25 | 25 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 26 | 26 | |
| 27 | -|Entity|source |frequency (%)| |
|
| 28 | -|:------:|:--------------:|:-------------:| |
|
| 29 | -|DLBCL |GAMBL genomes |8.22 | |
|
| 30 | -|DLBCL |Schmitz cohort|8.09 | |
|
| 31 | -|DLBCL |Reddy cohort |6.51 | |
|
| 32 | -|DLBCL |Chapuy cohort |6.84 | |
|
| 27 | +[[include:DLBCL_LRRN3.md]] |
|
| 33 | 28 | |
| 34 | 29 | ## Mutation pattern and selective pressure estimates |
| 35 | 30 |
LTB.md
| ... | ... | @@ -22,22 +22,15 @@ timeline |
| 22 | 22 | |Entity|Tier|Description | |
| 23 | 23 | |:------:|:----:|--------------------------------------| |
| 24 | 24 | ||1|high-confidence PMBL/cHL/GZL gene[@deschGenotypingCirculatingTumor2020]| |
| 25 | -| |1-a | aSHM target and high-confidence DLBCL gene [@chapuyMolecularSubtypesDiffuse2018]| |
|
| 26 | -| |1-a | aSHM target and high-confidence FL gene | |
|
| 27 | -| |2-a | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@paneaWholeGenomeLandscape2019]| |
|
| 25 | +| |1 | aSHM target and high-confidence DLBCL gene [@chapuyMolecularSubtypesDiffuse2018]| |
|
| 26 | +| |1 | aSHM target and high-confidence FL gene | |
|
| 27 | +| |2 | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@paneaWholeGenomeLandscape2019]| |
|
| 28 | 28 | |
| 29 | 29 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 30 | 30 | |
| 31 | -|Entity|source |frequency (%)| |
|
| 32 | -|:------:|:---------------------:|:-------------:| |
|
| 33 | -|DLBCL |GAMBL genomes |9.37 | |
|
| 34 | -|DLBCL |Schmitz cohort |8.51 | |
|
| 35 | -|DLBCL |Reddy cohort | NA | |
|
| 36 | -|DLBCL |Chapuy cohort |9.83 | |
|
| 37 | -|FL |GAMBL genomes |8.78 | |
|
| 38 | -|BL |GAMBL genomes+capture|3.00 | |
|
| 39 | -|BL |Thomas cohort |3.00 | |
|
| 40 | -|BL |Panea cohort |5.90 | |
|
| 31 | +[[include:DLBCL_LTB.md]] |
|
| 32 | +[[include:FL_LTB.md]] |
|
| 33 | +[[include:BL_LTB.md]] |
|
| 41 | 34 | |
| 42 | 35 | ## Mutation pattern and selective pressure estimates |
| 43 | 36 |
MEF2B.md
| ... | ... | @@ -31,17 +31,8 @@ timeline |
| 31 | 31 | |
| 32 | 32 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 33 | 33 | |
| 34 | -|Entity|source |frequency (%)| |
|
| 35 | -|:------:|:---------------------:|:-------------:| |
|
| 36 | -|BL |GAMBL genomes+capture| 1.39 | |
|
| 37 | -|BL |Thomas cohort | 0.80 | |
|
| 38 | -|BL |Panea cohort | 3.00 | |
|
| 39 | -|DLBCL |GAMBL genomes |11.28 | |
|
| 40 | -|DLBCL |Schmitz cohort | 9.79 | |
|
| 41 | -|DLBCL |Reddy cohort | 5.91 | |
|
| 42 | -|DLBCL |Chapuy cohort | 5.56 | |
|
| 43 | -|FL |GAMBL genomes |12.93 | |
|
| 44 | -|MCL |GAMBL genomes | 5.69 | |
|
| 34 | +[[include:DLBCL_MEF2B.md]] |
|
| 35 | +[[include:FL_MEF2B.md]] |
|
| 45 | 36 | |
| 46 | 37 | ## Mutation pattern and selective pressure estimates |
| 47 | 38 |