4eade68b8438fde362a72ca3beb1d0b9aa4e80c2
CD83.md
| ... | ... | @@ -7,22 +7,22 @@ CD83 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) |
| 7 | 7 | |
| 8 | 8 | |Entity|Tier|Description | |
| 9 | 9 | |:------:|:----:|--------------------------------------| |
| 10 | -|BL |2-a | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous | |
|
| 11 | 10 | |DLBCL |1-a | aSHM target and high-confidence DLBCL gene | |
| 12 | 11 | |FL |1-a | aSHM target and high-confidence FL gene | |
| 12 | +|BL |2-a | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous | |
|
| 13 | 13 | |
| 14 | 14 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 15 | 15 | |
| 16 | 16 | |Entity|source |frequency (%)| |
| 17 | 17 | |:------:|:---------------------:|:-------------:| |
| 18 | -|BL |GAMBL genomes+capture|1.15 | |
|
| 19 | -|BL |Thomas cohort |1.70 | |
|
| 20 | -|BL |Panea cohort | NA | |
|
| 21 | 18 | |DLBCL |GAMBL genomes |4.40 | |
| 22 | 19 | |DLBCL |Schmitz cohort |5.74 | |
| 23 | 20 | |DLBCL |Reddy cohort |5.81 | |
| 24 | 21 | |DLBCL |Chapuy cohort |7.26 | |
| 25 | 22 | |FL |GAMBL genomes |1.85 | |
| 23 | +|BL |GAMBL genomes+capture|1.15 | |
|
| 24 | +|BL |Thomas cohort |1.70 | |
|
| 25 | +|BL |Panea cohort | NA | |
|
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 |