54f95e6bc45cef4e147c372880261c167fe970a0
HIST1H1D.md
| ... | ... | @@ -36,3 +36,8 @@ Mutations are often found in the globular domain of the protein, which is critic |
| 36 | 36 | |
| 37 | 37 | [[include:browser_HIST1H1D.md]] |
| 38 | 38 | |
| 39 | + |
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| 40 | +[[include:tables/mermaid_HIST1H1D.md]] |
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| 41 | + |
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| 42 | +## References |
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| 43 | + |
HIST1H2AG.md
| ... | ... | @@ -9,8 +9,6 @@ nocite: | |
| 9 | 9 | |
| 10 | 10 | |
| 11 | 11 | |
| 12 | - |
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| 13 | - |
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| 14 | 12 | ## Relevance tier by entity |
| 15 | 13 | |
| 16 | 14 | [[include:table1_HIST1H2AG.md]] |
| ... | ... | @@ -23,26 +21,12 @@ nocite: | |
| 23 | 21 | |
| 24 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 23 | |
| 26 | -|Entity|source |frequency (%)| |
|
| 27 | -|:------:|:---------------------:|:-------------:| |
|
| 28 | -|BL |GAMBL genomes+capture|1.39 | |
|
| 29 | -|BL |Thomas cohort |2.50 | |
|
| 30 | -|BL |Panea cohort |1.00 | |
|
| 31 | -|DLBCL |GAMBL genomes |3.44 | |
|
| 32 | -|DLBCL |Schmitz cohort |3.62 | |
|
| 33 | -|DLBCL |Reddy cohort |1.90 | |
|
| 34 | -|DLBCL |Chapuy cohort |2.99 | |
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| 35 | -|FL |GAMBL genomes |2.08 | |
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| 24 | +### DLBCL |
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| 25 | +[[include:tables/DLBCL_HIST1H2AG]] |
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| 36 | 26 | |
| 37 | 27 | ## Mutation pattern and selective pressure estimates |
| 38 | 28 | |
| 39 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 40 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
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| 41 | -|BL |No |No |3.809 |0 | |
|
| 42 | -|DLBCL |No |No |5.602 |0 | |
|
| 43 | -|FL |No |No |0.405 |0 | |
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| 44 | - |
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| 45 | - |
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| 29 | +[[include:tables/dnds_HIST1H2AG.md]] |
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| 46 | 30 | |
| 47 | 31 | ## HIST1H2AG Hotspots |
| 48 | 32 | |
| ... | ... | @@ -56,3 +40,7 @@ nocite: | |
| 56 | 40 | |
| 57 | 41 | [[include:browser_HIST1H2AG.md]] |
| 58 | 42 | |
| 43 | +[[include:tables/mermaid_HIST1H2AG.md]] |
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| 44 | + |
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| 45 | +## References |
|
| 46 | + |
browser_HIST1H1D.md
| ... | ... | @@ -14,6 +14,6 @@ View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/H |
| 14 | 14 | <!-- DLBCL: morinMutationalStructuralAnalysis2013 --> |
| 15 | 15 | <!-- MZL: jalladesExomeSequencingIdentifies2017 --> |
| 16 | 16 | |
| 17 | -[[include:mermaid_HIST1H1D.md]] |
|
| 17 | +[[include:tables/mermaid_HIST1H1D.md]] |
|
| 18 | 18 | |
| 19 | 19 | ## References |