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CD274.md
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| 1 | 1 | # CD274 |
| 2 | 2 | ## Overview |
| 3 | -Mutations in the CD274 gene in B-cell lymphomas, such as DLBCL, are relatively rare.<sup>1</sup> Although rare, mutations have the potential to impact PD-L1 expression and could be relevant in the context of immune checkpoint inhibitors. |
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| 3 | +the CD274 gene encodes the programmed death-ligand 1 (PD-L1). Mutations in B-cell lymphomas, such as DLBCL, are relatively rare.<sup>1</sup> Although rare, mutations have the potential to impact PD-L1 expression and could be relevant in the context of immune checkpoint inhibitors. |
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| 4 | 4 | |
| 5 | 5 | ## Relevance tier by entity |
| 6 | 6 |