HLA-A.md
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## Mutation incidence in large patient cohorts (GAMBL reanalysis)
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-|Entity |Samples/Cohort |Mutation incidence (95% CI) |
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-|:------|:--------------------|:---------------------------|
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-|DLBCL |GAMBL without Reddy |0.0985 [0.0808,0.1163] |
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-|DLBCL |GAMBL with Reddy |0.0112 [0.0062,0.0162] |
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-|DLBCL |BC |0.0987 [0.0595,0.1378] |
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-|DLBCL |Dana-Farber[@chapuyMolecularSubtypesDiffuse2018] |0.0924 [0.0598,0.125] |
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-|DLBCL |NCI[@schmitzGeneticsPathogenesisDiffuse2018] |0.1106 [0.0823,0.139] |
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-|DLBCL |Reddy[@reddyGeneticFunctionalDrivers2017] |0.0037 [0,0.0089] |
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-|DLBCL |DLBCL_ICGC[@hubschmannMutationalMechanismsShaping2021] |0.0706 [0.0161,0.125] |
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-
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+|pathology |Samples |Incidence estimate |
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+ |:---------|:-------------------|:----------------------|
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+ |DLBCL |GAMBL without Reddy[@reddyGeneticFunctionalDrivers2017] |0.0985 [0.0808,0.1163] |
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+ |DLBCL |GAMBL with Reddy[@reddyGeneticFunctionalDrivers2017] |0.0112 [0.0062,0.0162] |
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+ |DLBCL |BC |0.0987 [0.0595,0.1378] |
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+ |DLBCL |Dana-Farber |0.0924 [0.0598,0.125] |
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+ |DLBCL |NCI |0.1106 [0.0823,0.139] |
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+ |DLBCL |Reddy[@reddyGeneticFunctionalDrivers2017] |0.0037 [0,0.0089] |
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+ |DLBCL |DLBCL_ICGC |0.0706 [0.0161,0.125] |
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## Mutation pattern and selective pressure estimates
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|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)|