Changes in 5d2d1df: Updated MPEG1 (markdown)

				MPEG1.md
			
          @@ -1,6 +1,6 @@

           # MPEG1

           ## Overview

          -MPEG1 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) affected by aberrant somatic hypermutation in B-cell lymphomas, which complicates the interpretation of mutations at this locus.

          +Mutations in MPEG1 have been described in DLBCL with the overall rate of mutations somewhat variable across studies. MPEG1 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) affected by aberrant somatic hypermutation in B-cell lymphomas, which complicates the interpretation of mutations at this locus. Coding and non-coding MPEG1 mutations are a feature of the MCD genetic subgroup of DLBCL. 

           ## Relevance tier by entity

          @@ -26,10 +26,6 @@ MPEG1 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm)

           |FL    |No  |No                   |4.371           |0.000           |

          -> [!NOTE]

          -> First described in DLBCL in 2013 by [Morin RD](https://pubmed.ncbi.nlm.nih.gov/23699601)

          -

          -

           View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/MPEG1_protein.html)  or [hg38](https://morinlab.github.io/LLMPP/GAMBL/MPEG1_protein_hg38.html)

           View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/MPEG1.html)  or [hg38](https://morinlab.github.io/LLMPP/GAMBL/MPEG1_hg38.html)

          @@ -37,3 +33,7 @@ View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/M

           ![image](images/proteinpaint/MPEG1.svg)

           ## MPEG1 Expression

           ![image](images/gene_expression/MPEG1_by_pathology.svg)

          +

          +## References

          +1. *Morin RD, Mungall K, Pleasance E, Mungall AJ, Goya R, Huff RD, Scott DW, Ding J, Roth A, Chiu R, Corbett RD, Chan FC, Mendez-Lago M, Trinh DL, Bolger-Munro M, Taylor G, Hadj Khodabakhshi A, Ben-Neriah S, Pon J, Meissner B, Woolcock B, Farnoud N, Rogic S, Lim EL, Johnson NA, Shah S, Jones S, Steidl C, Holt R, Birol I, Moore R, Connors JM, Gascoyne RD, Marra MA. Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing. Blood. 2013 Aug 15;122(7):1256-65. doi: 10.1182/blood-2013-02-483727. Epub 2013 May 22. PMID: 23699601; PMCID: PMC3744992.*

          +

...	...	@@ -1,6 +1,6 @@
1	1	# MPEG1
2	2	## Overview
3		-MPEG1 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) affected by aberrant somatic hypermutation in B-cell lymphomas, which complicates the interpretation of mutations at this locus.
	3	+Mutations in MPEG1 have been described in DLBCL with the overall rate of mutations somewhat variable across studies. MPEG1 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) affected by aberrant somatic hypermutation in B-cell lymphomas, which complicates the interpretation of mutations at this locus. Coding and non-coding MPEG1 mutations are a feature of the MCD genetic subgroup of DLBCL.
4	4
5	5	## Relevance tier by entity
6	6
...	...	@@ -26,10 +26,6 @@ MPEG1 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm)
26	26	\|FL \|No \|No \|4.371 \|0.000 \|
27	27
28	28
29		-> [!NOTE]
30		-> First described in DLBCL in 2013 by [Morin RD](https://pubmed.ncbi.nlm.nih.gov/23699601)
31		-
32		-
33	29	View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/MPEG1_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/MPEG1_protein_hg38.html)
34	30
35	31	View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/MPEG1.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/MPEG1_hg38.html)
...	...	@@ -37,3 +33,7 @@ View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/M
37	33	![image](images/proteinpaint/MPEG1.svg)
38	34	## MPEG1 Expression
39	35	![image](images/gene_expression/MPEG1_by_pathology.svg)
	36	+
	37	+## References
	38	+1. Morin RD, Mungall K, Pleasance E, Mungall AJ, Goya R, Huff RD, Scott DW, Ding J, Roth A, Chiu R, Corbett RD, Chan FC, Mendez-Lago M, Trinh DL, Bolger-Munro M, Taylor G, Hadj Khodabakhshi A, Ben-Neriah S, Pon J, Meissner B, Woolcock B, Farnoud N, Rogic S, Lim EL, Johnson NA, Shah S, Jones S, Steidl C, Holt R, Birol I, Moore R, Connors JM, Gascoyne RD, Marra MA. Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing. Blood. 2013 Aug 15;122(7):1256-65. doi: 10.1182/blood-2013-02-483727. Epub 2013 May 22. PMID: 23699601; PMCID: PMC3744992.
	39	+