66e09f1c2408deb62a7a70ad7e0910d565ffc073
BL_Tier1.md
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| 1 | -### *32 total* |
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| 2 | 1 | |
| 3 | -|Gene|Summary| First BL study | Other entities | QC result | |
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| 4 | -|:-:|:--:|:-:|:-|:-| |
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| 5 | -|[ARID1A](ARID1A)|Tier 1 |[Love et al](papers/loveGeneticLandscapeMutations2012)|[@krysiakRecurrentSomaticMutations2017; @rossiCodingGenomeSplenic2012; @wienandGenomicAnalysesFlowsorted2019; @zhangGeneticHeterogeneityDiffuse2013]|| |
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| 6 | -|[BACH2](BACH2)|Tier 1 |[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)||| |
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| 7 | -|[BCL6](BCL6)|Tier 1 |[Love et al](papers/loveGeneticLandscapeMutations2012)|[@drevalGeneticSubdivisionsFollicular2023; @morinFrequentMutationHistonemodifying2011]|PASS| |
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| 8 | -|[BCL7A](BCL7A)|Tier 1 GE[@grandeGenomewideDiscoverySomatic2019], FE[@balinas-gaviraFrequentMutationsAminoterminal2020], aSHM|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)|[@krysiakRecurrentSomaticMutations2017; @morinFrequentMutationHistonemodifying2011; @reichelFlowSortingExome2015]|| |
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| 9 | -|[BMP7](BMP7)|Tier 1 GE[@paneaWholeGenomeLandscape2019]|[Panea et al](papers/paneaWholeGenomeLandscape2019)||| |
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| 10 | -|[CCND3](CCND3)|Tier 1 GE[@richterRecurrentMutationID32012], FE[@schmitzBurkittLymphomaPathogenesis2012]|[Richter et al](papers/richterRecurrentMutationID32012)|[@deschGenotypingCirculatingTumor2020; @jalladesExomeSequencingIdentifies2017; @morinFrequentMutationHistonemodifying2011]|| |
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| 11 | -|[CHD8](CHD8)|Tier 1 GE[@grandeGenomewideDiscoverySomatic2019]|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)||| |
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| 12 | -|[CREBBP](CREBBP)|Tier 1 GE[@loveGeneticLandscapeMutations2012], FE[@pasqualucciInactivatingMutationsAcetyltransferase2011]|[Love et al](papers/loveGeneticLandscapeMutations2012)|[@dunsCharacterizationDLBCLPMBL2021; @parryWholeExomeSequencing2013; @pasqualucciInactivatingMutationsAcetyltransferase2011]|PASS| |
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| 13 | -|[DDX3X](DDX3X)|Tier 1 GE[@schmitzBurkittLymphomaPathogenesis2012], FE[@gongSequentialInverseDysregulation2021]|[Schmitz et al](papers/schmitzBurkittLymphomaPathogenesis2012)|[@mottokIntegrativeGenomicAnalysis2019; @reddyGeneticFunctionalDrivers2017]|| |
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| 14 | -|[FBXO11](FBXO11)|Tier 1 GE[@richterRecurrentMutationID32012], FE[@duanFBXO11TargetsBCL62011]|[Richter et al](papers/richterRecurrentMutationID32012)|[@arthurGenomewideDiscoverySomatic2018; @parryWholeExomeSequencing2013]|| |
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| 15 | -|[FOXO1](FOXO1)|Tier 1 GE[@schmitzBurkittLymphomaPathogenesis2012], FE[@trinhAnalysisFOXO1Mutations]|[Schmitz et al](papers/schmitzBurkittLymphomaPathogenesis2012)|[@dunsCharacterizationDLBCLPMBL2021; @morinFrequentMutationHistonemodifying2011]|| |
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| 16 | -|[GNA13](GNA13)|Tier 1 GE[@loveGeneticLandscapeMutations2012], FE[@muppidiLossSignalingGa132014]|[Love et al](papers/loveGeneticLandscapeMutations2012)|[@morinFrequentMutationHistonemodifying2011; @reichelFlowSortingExome2015]|| |
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| 17 | -|[GNAI2](GNAI2)|Tier 1 GE[@grandeGenomewideDiscoverySomatic2019], FE[@muppidiLossSignalingGa132014]|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)|[@drevalGeneticSubdivisionsFollicular2023; @morinMutationalStructuralAnalysis2013]|| |
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| 18 | -|[HIST1H1E](HIST1H1E)|Tier 1 GE[@grandeGenomewideDiscoverySomatic2019], aSHM|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)|[@krysiakRecurrentSomaticMutations2017; @lohrDiscoveryPrioritizationSomatic2012; @reichelFlowSortingExome2015]|| |
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| 19 | -|[HNRNPU](HNRNPU)|Tier 1 GE[@paneaWholeGenomeLandscape2019]|[Panea et al](papers/paneaWholeGenomeLandscape2019)|[@reddyGeneticFunctionalDrivers2017]|| |
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| 20 | -|[ID3](ID3)|Tier 1 GE[@richterRecurrentMutationID32012]|[Richter et al](papers/richterRecurrentMutationID32012)|[@schmitzGeneticsPathogenesisDiffuse2018; @spinaGeneticsNodalMarginal2016]|| |
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| 21 | -|[KMT2D](KMT2D)|Tier 1 GE[@grandeGenomewideDiscoverySomatic2019], FE[@zhangDisruptionKMT2DPerturbs2015]|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)|[@beaLandscapeSomaticMutations2013; @deschGenotypingCirculatingTumor2020; @morinFrequentMutationHistonemodifying2011; @rossiCodingGenomeSplenic2012]|| |
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| 22 | -|[MYC](MYC)|Tier 1 GE[@johnstonCmycHypermutationBurkitt1992], FE[@freieGermlinePointMutation2024], aSHM|[Johnston et al](papers/johnstonCmycHypermutationBurkitt1992)|[@dunsCharacterizationDLBCLPMBL2021; @jalladesExomeSequencingIdentifies2017; @pasqualucciHypermutationMultipleProtooncogenes2001]|| |
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| 23 | -|[P2RY8](P2RY8)|Tier 1 GE[@muppidiLossSignalingGa132014], FE[@muppidiLossSignalingGa132014]|[Muppidi et al](papers/muppidiLossSignalingGa132014)|[@drevalGeneticSubdivisionsFollicular2023; @lohrDiscoveryPrioritizationSomatic2012]|| |
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| 24 | -|[PCBP1](PCBP1)|Tier 1 GE[@schmitzBurkittLymphomaPathogenesis2012]|[Schmitz et al](papers/schmitzBurkittLymphomaPathogenesis2012)||| |
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| 25 | -|[PHF6](PHF6)|Tier 1 GE[@thomasGeneticSubgroupsInform2023]|[Thomas et al](papers/thomasGeneticSubgroupsInform2023)|[@reddyGeneticFunctionalDrivers2017]|| |
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| 26 | -|[PTEN](PTEN)|Tier 1 GE[@loveGeneticLandscapeMutations2012], FE[@pfeiferPTENLossDefines2013]|[Love et al](papers/loveGeneticLandscapeMutations2012)|[@reddyGeneticFunctionalDrivers2017]|| |
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| 27 | -|[RFX7](RFX7)|Tier 1 GE[@grandeGenomewideDiscoverySomatic2019], FE[@weberPiggyBacTransposonTools2019]|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)|[@arthurGenomewideDiscoverySomatic2018]|| |
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| 28 | -|[RHOA](RHOA)|Tier 1 GE[@richterRecurrentMutationID32012], FE[@ohayreInactivatingMutationsGNA132016]|[Richter et al](papers/richterRecurrentMutationID32012)|[@zhangGeneticHeterogeneityDiffuse2013]|| |
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| 29 | -|[SIN3A](SIN3A)|Tier 1 GE[@grandeGenomewideDiscoverySomatic2019]|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)|[@chapuyMolecularSubtypesDiffuse2018; @rossiCodingGenomeSplenic2012]|| |
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| 30 | -|[SMARCA4](SMARCA4)|Tier 1 GE[@richterRecurrentMutationID32012], FE[@fernandoFunctionalCharacterizationSMARCA42020]|[Richter et al](papers/richterRecurrentMutationID32012)|[@krysiakRecurrentSomaticMutations2017; @nadeuGenomicEpigenomicInsights2020; @reddyGeneticFunctionalDrivers2017]|| |
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| 31 | -|[TCF3](TCF3)|Tier 1 GE[@schmitzBurkittLymphomaPathogenesis2012]|[Schmitz et al](papers/schmitzBurkittLymphomaPathogenesis2012)||| |
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| 32 | -|[TCL1A](TCL1A)|Tier 1 GE[@grandeGenomewideDiscoverySomatic2019], aSHM|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)|[@reddyGeneticFunctionalDrivers2017]|| |
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| 33 | -|[TFAP4](TFAP4)|Tier 1 GE[@grandeGenomewideDiscoverySomatic2019]|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)||| |
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| 34 | -|[TP53](TP53)|Tier 1 GE[@wildaInactivationARFMDM2p53Pathway2004], FE[@katoUnderstandingFunctionstructureFunctionmutation2003]|[Wilda et al](papers/wildaInactivationARFMDM2p53Pathway2004)|[@beaLandscapeSomaticMutations2013; @morinFrequentMutationHistonemodifying2011; @rossiCodingGenomeSplenic2012; @tiacciPervasiveMutationsJAKSTAT2018]|| |
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| 35 | -|[USP7](USP7)|Tier 1 GE[@grandeGenomewideDiscoverySomatic2019]|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)|[@arthurGenomewideDiscoverySomatic2018]|| |
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| 36 | -|[WNK1](WNK1)|Tier 1 GE[@thomasGeneticSubgroupsInform2023]|[Thomas et al](papers/thomasGeneticSubgroupsInform2023)|[@hubschmannMutationalMechanismsShaping2021; @jalladesExomeSequencingIdentifies2017]|| |
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| ... | ... | \ No newline at end of file |
| 0 | +|Gene|Status| First BL study | |
|
| 1 | +|:-:|:--:|:-:| |
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| 2 | +|[ARID1A](ARID1A)|Tier 1|[Love et al](papers/loveGeneticLandscapeMutations2012)| |
|
| 3 | +|[BACH2](BACH2)|Tier 1|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)| |
|
| 4 | +|[BCL6](BCL6)|Tier 1|[Love et al](papers/loveGeneticLandscapeMutations2012)| |
|
| 5 | +|[BCL7A](BCL7A)|Tier 1|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)| |
|
| 6 | +|[BMP7](BMP7)|Tier 1|[Panea et al](papers/paneaWholeGenomeLandscape2019)| |
|
| 7 | +|[CCND3](CCND3)|Tier 1|[Richter et al](papers/richterRecurrentMutationID32012)| |
|
| 8 | +|[CHD8](CHD8)|Tier 1|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)| |
|
| 9 | +|[CREBBP](CREBBP)|Tier 1|[Love et al](papers/loveGeneticLandscapeMutations2012)| |
|
| 10 | +|[DDX3X](DDX3X)|Tier 1|[Schmitz et al](papers/schmitzBurkittLymphomaPathogenesis2012)| |
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| 11 | +|[EZH2](EZH2)|Tier 1|[Love et al](papers/loveGeneticLandscapeMutations2012)| |
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| 12 | +|[FBXO11](FBXO11)|Tier 1|[Richter et al](papers/richterRecurrentMutationID32012)| |
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| 13 | +|[FOXO1](FOXO1)|Tier 1|[Schmitz et al](papers/schmitzBurkittLymphomaPathogenesis2012)| |
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| 14 | +|[GNA13](GNA13)|Tier 1|[Schmitz et al](papers/schmitzBurkittLymphomaPathogenesis2012)| |
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| 15 | +|[GNAI2](GNAI2)|Tier 1|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)| |
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| 16 | +|[HIST1H1E](HIST1H1E)|Tier 1|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)| |
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| 17 | +|[HNRNPU](HNRNPU)|Tier 1|[Panea et al](papers/paneaWholeGenomeLandscape2019)| |
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| 18 | +|[ID3](ID3)|Tier 1|[Richter et al](papers/richterRecurrentMutationID32012)| |
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| 19 | +|[IGLL5](IGLL5)|Tier 1|[Panea et al](papers/paneaWholeGenomeLandscape2019)| |
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| 20 | +|[KMT2D](KMT2D)|Tier 1|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)| |
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| 21 | +|[MYC](MYC)|Tier 1|[Johnston et al](papers/johnstonCmycHypermutationBurkitt1992)| |
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| 22 | +|[P2RY8](P2RY8)|Tier 1|[Muppidi et al](papers/muppidiLossSignalingGa132014)| |
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| 23 | +|[PCBP1](PCBP1)|Tier 1|[Schmitz et al](papers/schmitzBurkittLymphomaPathogenesis2012)| |
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| 24 | +|[PHF6](PHF6)|Tier 1|[Thomas et al](papers/thomasGeneticSubgroupsInform2023)| |
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| 25 | +|[PTEN](PTEN)|Tier 1|[Love et al](papers/loveGeneticLandscapeMutations2012)| |
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| 26 | +|[RFX7](RFX7)|Tier 1|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)| |
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| 27 | +|[RHOA](RHOA)|Tier 1|[Richter et al](papers/richterRecurrentMutationID32012)| |
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| 28 | +|[SIN3A](SIN3A)|Tier 1|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)| |
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| 29 | +|[SMARCA4](SMARCA4)|Tier 1|[Richter et al](papers/richterRecurrentMutationID32012)| |
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| 30 | +|[TCF3](TCF3)|Tier 1|[Schmitz et al](papers/schmitzBurkittLymphomaPathogenesis2012)| |
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| 31 | +|[TCL1A](TCL1A)|Tier 1|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)| |
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| 32 | +|[TFAP4](TFAP4)|Tier 1|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)| |
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| 33 | +|[TP53](TP53)|Tier 1|[Wilda et al](papers/wildaInactivationARFMDM2p53Pathway2004)| |
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| 34 | +|[USP7](USP7)|Tier 1|[Grande et al](papers/grandeGenomewideDiscoverySomatic2019)| |
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| 35 | +|[WNK1](WNK1)|Tier 1|[Thomas et al](papers/thomasGeneticSubgroupsInform2023)| |
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