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gbanco4 committed 2024-12-16 23:56:41 -0800 commit 676122ab200e6c20f17f5058c0bd9927c20d664c

				P2RY8.md
			
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          +## Overview

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           P2RY8 encodes a G protein–coupled receptor that is expressed on germinal center B cells. Signals through this receptor promote confinement of B cells to the GC niche.<sup>1</sup> Downstream signaling through Galpha13 (encoded by GNA13) and S1PR2 is distrupted by mutations of one of these genes in GC lymphomas including the GCB subgroup of DLBCL and BL.[muppidiLossSignalingGa132014]

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	8	+## Overview
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7	10	P2RY8 encodes a G protein–coupled receptor that is expressed on germinal center B cells. Signals through this receptor promote confinement of B cells to the GC niche.<sup>1</sup> Downstream signaling through Galpha13 (encoded by GNA13) and S1PR2 is distrupted by mutations of one of these genes in GC lymphomas including the GCB subgroup of DLBCL and BL.[muppidiLossSignalingGa132014]
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