S1PR2.md
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@@ -13,8 +13,14 @@ S1PR2 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm)
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%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
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timeline
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title Publication timing
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- 2011-07-27 : Morin : DLBCL
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- 2014-12-11 : Muppidi : BL
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+2011-07-27 : Morin : DLBCL
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+2012-03-06 : Lohr : DLBCL
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+2013-08-15 : Morin : DLBCL
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+2014-12-11 : Muppidi : BL
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+2017-10-10 : Reddy : DLBCL
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+2018-04-12 : Schmitz : DLBCL
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+2018-10-01 : Arthur : DLBCL
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+
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```
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## Relevance tier by entity
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@@ -22,9 +28,9 @@ timeline
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|Entity|Tier|Description |
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|:------:|:----:|--------------------------------------|
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|![PMBL](images/icons/PMBL_tier1.png)|1|high-confidence PMBL/cHL/GZL gene|
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-|![BL](images/icons/BL_tier2.png) |2-a | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@muppidiLossSignalingGa132014b]|
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-|![DLBCL](images/icons/DLBCL_tier1.png) |1-a | aSHM target and high-confidence DLBCL gene [@morinFrequentMutationHistonemodifying2011]|
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-|![FL](images/icons/FL_tier1.png) |1-a | aSHM target and high-confidence FL gene |
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+|![BL](images/icons/BL_tier2.png) |2 | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@muppidiLossSignalingGa132014b]|
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+|![DLBCL](images/icons/DLBCL_tier1.png) |1 | aSHM target and high-confidence DLBCL gene [@morinFrequentMutationHistonemodifying2011; @lohrDiscoveryPrioritizationSomatic2012a; @morinMutationalStructuralAnalysis2013]|
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+|![FL](images/icons/FL_tier1.png) |1 | aSHM target and high-confidence FL gene |
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## Mutation incidence in large patient cohorts (GAMBL reanalysis)
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