7702a4cb8e306f54b722f3f3ff947abeb4ad60c1
BL_genes.md
| ... | ... | @@ -0,0 +1,553 @@ |
| 1 | +# BL genes |
|
| 2 | + |
|
| 3 | +## Origins of BL genes |
|
| 4 | + |
|
| 5 | +## Tier 1 BL genes |
|
| 6 | + |
|
| 7 | +| Gene | Tier | Relevant references | |
|
| 8 | +|:------------------:|:----:|:-------------------------------------------------------------:| |
|
| 9 | +| [ARID1A](ARID1A) | 1 | Love et al. 2012; Krysiak et al. 2017; Zhang et al. 2013 | |
|
| 10 | +| [BMP7](BMP7) | 1 | Panea et al. 2019 | |
|
| 11 | +| [CCND3](CCND3) | 1 | Morin et al. 2011; Richter et al. 2012 | |
|
| 12 | +| [CHD8](CHD8) | 1 | Grande et al. 2019; Reddy et al. 2017 | |
|
| 13 | +| [DDX3X](DDX3X) | 1 | Schmitz et al. 2012, 2018 | |
|
| 14 | +| [EIF4A1](EIF4A1) | 1 | Panea et al. 2019 | |
|
| 15 | +| [EPPK1](EPPK1) | 1 | Panea et al. 2019 | |
|
| 16 | +| [FBXO11](FBXO11) | 1 | Hübschmann et al. 2021; Richter et al. 2012 | |
|
| 17 | +| [FOXO1](FOXO1) | 1 | Schmitz et al. 2012; Morin et al. 2011 | |
|
| 18 | +| [GNA13](GNA13) | 1 | Love et al. 2012; Morin et al. 2011 | |
|
| 19 | +| [GNAI2](GNAI2) | 1 | Grande et al. 2019; Morin et al. 2013 | |
|
| 20 | +| [HNRNPU](HNRNPU) | 1a | Reddy et al. 2017; Panea et al. 2019 | |
|
| 21 | +| [ID3](ID3) | 1 | Schmitz et al. 2012; Richter et al. 2012 | |
|
| 22 | +| [KMT2D](KMT2D) | 1 | Morin et al. 2011; Grande et al. 2019 | |
|
| 23 | +| [MYC](MYC) | 1a | Johnston and Carroll 1992; L. Pasqualucci et al. 2001 | |
|
| 24 | +| [P2RY8](P2RY8) | 1 | Muppidi et al. 2014; Lohr et al. 2012 | |
|
| 25 | +| [PHF6](PHF6) | 1 | Reddy et al. 2017; Thomas et al. 2023 | |
|
| 26 | +| [PTEN](PTEN) | 1 | Love et al. 2012 | |
|
| 27 | +| [RFX7](RFX7) | 1 | Grande et al. 2019 | |
|
| 28 | +| [RHOA](RHOA) | 1 | Richter et al. 2012 | |
|
| 29 | +| [SIN3A](SIN3A) | 1 | Grande et al. 2019 | |
|
| 30 | +| [SMARCA4](SMARCA4) | 1 | Krysiak et al. 2017; Richter et al. 2012; Zhang et al. 2013 | |
|
| 31 | +| [TCF3](TCF3) | 1 | Schmitz et al. 2012 | |
|
| 32 | +| [TCL1A](TCL1A) | 1 | Grande et al. 2019 | |
|
| 33 | +| [TFAP4](TFAP4) | 1 | Grande et al. 2019 | |
|
| 34 | +| [TP53](TP53) | 1 | Morin et al. 2011; Wilda et al. 2004 | |
|
| 35 | +| [USP7](USP7) | 1 | Grande et al. 2019 | |
|
| 36 | +| [WNK1](WNK1) | 1 | Hübschmann et al. 2021; Thomas et al. 2023 | |
|
| 37 | + |
|
| 38 | +## Tier 2 BL genes |
|
| 39 | + |
|
| 40 | +| Gene | Tier | Relevant references | |
|
| 41 | +|:----------------------:|:----:|:-------------------------------------------------------------------:| |
|
| 42 | +| [ACAD9](ACAD9) | 2 | Love et al. 2012 | |
|
| 43 | +| [ACE](ACE) | 2 | Love et al. 2012 | |
|
| 44 | +| [ADAMTS5](ADAMTS5) | 2 | Burkhardt et al. 2022 | |
|
| 45 | +| [ADNP](ADNP) | 2 | Burkhardt et al. 2022 | |
|
| 46 | +| [AGO4](AGO4) | 2 | Burkhardt et al. 2022 | |
|
| 47 | +| [ALPK2](ALPK2) | 2 | Panea et al. 2019 | |
|
| 48 | +| [ARHGEF1](ARHGEF1) | 2 | Muppidi et al. 2014 | |
|
| 49 | +| [ATP2C2](ATP2C2) | 2 | Love et al. 2012 | |
|
| 50 | +| [BACH2](BACH2) | 2a | Grande et al. 2019 | |
|
| 51 | +| [BCL2](BCL2) | 2a | Burkhardt et al. 2022; Morin et al. 2011; Tanaka et al. 1992 | |
|
| 52 | +| [BCL6](BCL6) | 2a | Love et al. 2012; Morin et al. 2011 | |
|
| 53 | +| [BCL7A](BCL7A) | 2a | Grande et al. 2019; Krysiak et al. 2017; Arthur et al. 2018 | |
|
| 54 | +| [BRAF](BRAF) | 2 | Love et al. 2012; Tiacci et al. 2011 | |
|
| 55 | +| [BRD4](BRD4) | 2 | Love et al. 2012 | |
|
| 56 | +| [BTG1](BTG1) | 2a | Morin et al. 2011; Burkhardt et al. 2022 | |
|
| 57 | +| [BTG2](BTG2) | 2a | Love et al. 2012; Morin et al. 2011 | |
|
| 58 | +| [C16orf48](C16orf48) | 2 | Schmitz et al. 2012 | |
|
| 59 | +| [C6orf27](C6orf27) | 2 | Love et al. 2012 | |
|
| 60 | +| [CAD](CAD) | 2 | Love et al. 2012 | |
|
| 61 | +| [CARD11](CARD11) | 2 | Lenz et al. 2008; Morin et al. 2011; Panea et al. 2019 | |
|
| 62 | +| [CARD4](CARD4) | 2 | Love et al. 2012 | |
|
| 63 | +| [CCNF](CCNF) | 2 | Abate et al. 2015 | |
|
| 64 | +| [CCT6B](CCT6B) | 2 | Love et al. 2012 | |
|
| 65 | +| [CD79A](CD79A) | 2 | Burkhardt et al. 2022 | |
|
| 66 | +| [CD79B](CD79B) | 2 | Morin et al. 2011; Panea et al. 2019 | |
|
| 67 | +| [CD83](CD83) | 2a | Morin et al. 2013; Panea et al. 2019; Russler-Germain et al. 2023 | |
|
| 68 | +| [CDC73](CDC73) | 2 | Reddy et al. 2017; Love et al. 2012 | |
|
| 69 | +| [CDH17](CDH17) | 2 | Love et al. 2012 | |
|
| 70 | +| [CDKN2A](CDKN2A) | 2 | Morin et al. 2013; Grande et al. 2019 | |
|
| 71 | +| [CDKN2C](CDKN2C) | 2 | Thomas et al. 2023 | |
|
| 72 | +| [CHD4](CHD4) | 2 | Burkhardt et al. 2022 | |
|
| 73 | +| [COL4A2](COL4A2) | 2 | Love et al. 2012 | |
|
| 74 | +| [CPXM2](CPXM2) | 2 | Burkhardt et al. 2022 | |
|
| 75 | +| [CREBBP](CREBBP) | 2 | Love et al. 2012; Laura Pasqualucci, Dominguez-Sola, et al. 2011 | |
|
| 76 | +| [CTCF](CTCF) | 2 | Panea et al. 2019 | |
|
| 77 | +| [CXCR4](CXCR4) | 2a | Krysiak et al. 2017; Khodabakhshi et al. 2012; Panea et al. 2019 | |
|
| 78 | +| [CYB5D1](CYB5D1) | 2 | Love et al. 2012 | |
|
| 79 | +| [CYP4F22](CYP4F22) | 2 | Love et al. 2012 | |
|
| 80 | +| [DHCR7](DHCR7) | 2 | Schmitz et al. 2012 | |
|
| 81 | +| [DLGAP1](DLGAP1) | 2 | Love et al. 2012 | |
|
| 82 | +| [DNMT1](DNMT1) | 2 | Panea et al. 2019 | |
|
| 83 | +| [DTX1](DTX1) | 2a | Panea et al. 2019; Schmitz et al. 2018 | |
|
| 84 | +| [E2F2](E2F2) | 2 | Burkhardt et al. 2022 | |
|
| 85 | +| [EBF1](EBF1) | 2a | Bohle et al. 2013; Thomas et al. 2023 | |
|
| 86 | +| [EDNRB](EDNRB) | 2 | Burkhardt et al. 2022 | |
|
| 87 | +| [EHD1](EHD1) | 2 | Thomas et al. 2023 | |
|
| 88 | +| [EIF2C4](EIF2C4) | 2 | Love et al. 2012 | |
|
| 89 | +| [ELP2](ELP2) | 2 | Schmitz et al. 2012 | |
|
| 90 | +| [EML2](EML2) | 2 | Love et al. 2012 | |
|
| 91 | +| [ENTPD3](ENTPD3) | 2 | Love et al. 2012 | |
|
| 92 | +| [EP300](EP300) | 2 | Laura Pasqualucci, Dominguez-Sola, et al. 2011; Panea et al. 2019 | |
|
| 93 | +| [EPHB2](EPHB2) | 2 | Love et al. 2012 | |
|
| 94 | +| [ERAP1](ERAP1) | 2 | Burkhardt et al. 2022 | |
|
| 95 | +| [ETS1](ETS1) | 2a | Panea et al. 2019; Morin et al. 2011 | |
|
| 96 | +| [EXOSC6](EXOSC6) | 2 | Schmitz et al. 2012 | |
|
| 97 | +| [EZH2](EZH2) | 2 | Morin et al. 2010; Love et al. 2012 | |
|
| 98 | +| [FAM129B](FAM129B) | 2 | Love et al. 2012 | |
|
| 99 | +| [FGFR3](FGFR3) | 2 | Love et al. 2012 | |
|
| 100 | +| [FLYWCH1](FLYWCH1) | 2 | Schmitz et al. 2012 | |
|
| 101 | +| [FTCD](FTCD) | 2 | Love et al. 2012 | |
|
| 102 | +| [FZD3](FZD3) | 2 | Panea et al. 2019 | |
|
| 103 | +| [GGTLA4](GGTLA4) | 2 | Love et al. 2012 | |
|
| 104 | +| [GRB2](GRB2) | 2 | Laura Pasqualucci, Trifonov, et al. 2011; Panea et al. 2019 | |
|
| 105 | +| [GRIK5](GRIK5) | 2 | Love et al. 2012 | |
|
| 106 | +| [GTSE1](GTSE1) | 2 | Schmitz et al. 2012 | |
|
| 107 | +| [HIST1H1C](HIST1H1C) | 2a | Panea et al. 2019; Morin et al. 2011 | |
|
| 108 | +| [HIST1H1E](HIST1H1E) | 2a | Morin et al. 2013; Grande et al. 2019; Krysiak et al. 2017 | |
|
| 109 | +| [HIST1H2AG](HIST1H2AG) | 2a | Morin et al. 2013; Krysiak et al. 2017; Panea et al. 2019 | |
|
| 110 | +| [HIST1H2AM](HIST1H2AM) | 2a | Panea et al. 2019; Krysiak et al. 2017 | |
|
| 111 | +| [HIST1H2BK](HIST1H2BK) | 2a | Panea et al. 2019 | |
|
| 112 | +| [HIST1H3D](HIST1H3D) | 2a | Panea et al. 2019 | |
|
| 113 | +| [HIST1H3H](HIST1H3H) | 2a | Panea et al. 2019 | |
|
| 114 | +| [HIST1H3I](HIST1H3I) | 2a | Panea et al. 2019; Krysiak et al. 2017 | |
|
| 115 | +| [HIST1H3J](HIST1H3J) | 2a | Panea et al. 2019 | |
|
| 116 | +| [HIST1H4J](HIST1H4J) | 2a | Panea et al. 2019 | |
|
| 117 | +| [HLA-A](HLA-A) | 2 | | |
|
| 118 | +| [HLA-B](HLA-B) | 2 | | |
|
| 119 | +| [HLA-DMB](HLA-DMB) | 2 | | |
|
| 120 | +| [HLA-DQB1](HLA-DQB1) | 2 | Burkhardt et al. 2022 | |
|
| 121 | +| [ICK](ICK) | 2 | Love et al. 2012 | |
|
| 122 | +| [IGLL5](IGLL5) | 2a | Russler-Germain et al. 2023; Panea et al. 2019 | |
|
| 123 | +| [IKZF3](IKZF3) | 2a | Panea et al. 2019; Morin et al. 2013 | |
|
| 124 | +| [IRF8](IRF8) | 2a | Panea et al. 2019; Morin et al. 2011 | |
|
| 125 | +| [ITPR3](ITPR3) | 2 | Love et al. 2012 | |
|
| 126 | +| [KANK2](KANK2) | 2 | Schmitz et al. 2012 | |
|
| 127 | +| [KCNK10](KCNK10) | 2 | Panea et al. 2019 | |
|
| 128 | +| [KIFC3](KIFC3) | 2 | Love et al. 2012 | |
|
| 129 | +| [KLHL26](KLHL26) | 2 | Burkhardt et al. 2022 | |
|
| 130 | +| [KLHL6](KLHL6) | 2a | Morin et al. 2011; Panea et al. 2019 | |
|
| 131 | +| [KMT2C](KMT2C) | 2 | Zhou et al. 2019; Zhang et al. 2013 | |
|
| 132 | +| [LTB](LTB) | 2a | Panea et al. 2019; Chapuy et al. 2018 | |
|
| 133 | +| [MAP3K6](MAP3K6) | 2 | Love et al. 2012 | |
|
| 134 | +| [MCL1](MCL1) | 2 | Panea et al. 2019; Reddy et al. 2017 | |
|
| 135 | +| [MIR142](MIR142) | 2a | Grande et al. 2019; Kwanhian et al. 2012 | |
|
| 136 | +| [MKI67](MKI67) | 2 | Russler-Germain et al. 2023; Schmitz et al. 2012 | |
|
| 137 | +| [MME](MME) | 2 | Panea et al. 2019 | |
|
| 138 | +| [MTOR](MTOR) | 2 | Zhang et al. 2013; Panea et al. 2019 | |
|
| 139 | +| [MYH10](MYH10) | 2 | Love et al. 2012 | |
|
| 140 | +| [MYO18A](MYO18A) | 2 | Schmitz et al. 2012 | |
|
| 141 | +| [NBEAL1](NBEAL1) | 2 | Love et al. 2012 | |
|
| 142 | +| [NCOR2](NCOR2) | 2 | Schmitz et al. 2012 | |
|
| 143 | +| [NOA1](NOA1) | 2 | Burkhardt et al. 2022 | |
|
| 144 | +| [NOTCH1](NOTCH1) | 2 | Laura Pasqualucci, Trifonov, et al. 2011; Love et al. 2012 | |
|
| 145 | +| [NOTCH2](NOTCH2) | 2 | Trøen et al. 2008; Panea et al. 2019 | |
|
| 146 | +| [NRXN2](NRXN2) | 2 | Love et al. 2012 | |
|
| 147 | +| [P2RY2](P2RY2) | 2 | Love et al. 2012 | |
|
| 148 | +| [PABPC4L](PABPC4L) | 2 | Panea et al. 2019 | |
|
| 149 | +| [PC](PC) | 2 | Love et al. 2012 | |
|
| 150 | +| [PCBP1](PCBP1) | 2 | Schmitz et al. 2012 | |
|
| 151 | +| [PCDHA11](PCDHA11) | 2 | Panea et al. 2019 | |
|
| 152 | +| [PDCD11](PDCD11) | 2 | Schmitz et al. 2012 | |
|
| 153 | +| [PDZRN3](PDZRN3) | 2 | Panea et al. 2019 | |
|
| 154 | +| [PIK3R1](PIK3R1) | 2 | Zhang et al. 2013; Panea et al. 2019 | |
|
| 155 | +| [PIM1](PIM1) | 2a | L. Pasqualucci et al. 2001; Burkhardt et al. 2022 | |
|
| 156 | +| [PLCG2](PLCG2) | 2 | Panea et al. 2019 | |
|
| 157 | +| [POLRMT](POLRMT) | 2 | Love et al. 2012 | |
|
| 158 | +| [POR](POR) | 2 | Love et al. 2012 | |
|
| 159 | +| [PPP6R2](PPP6R2) | 2 | Burkhardt et al. 2022 | |
|
| 160 | +| [PREX1](PREX1) | 2 | Burkhardt et al. 2022 | |
|
| 161 | +| [PRSS22](PRSS22) | 2 | Love et al. 2012 | |
|
| 162 | +| [PTPRN](PTPRN) | 2 | Love et al. 2012 | |
|
| 163 | +| [PXDNL](PXDNL) | 2 | Panea et al. 2019 | |
|
| 164 | +| [RAC2](RAC2) | 2 | Hübschmann et al. 2021; Panea et al. 2019 | |
|
| 165 | +| [RANBP6](RANBP6) | 2 | Love et al. 2012 | |
|
| 166 | +| [RBP3](RBP3) | 2 | Love et al. 2012 | |
|
| 167 | +| [RET](RET) | 2 | Love et al. 2012 | |
|
| 168 | +| [REV3L](REV3L) | 2 | Burkhardt et al. 2022 | |
|
| 169 | +| [RNF144B](RNF144B) | 2 | Panea et al. 2019 | |
|
| 170 | +| [RPL10](RPL10) | 2 | Burkhardt et al. 2022 | |
|
| 171 | +| [S1PR2](S1PR2) | 2a | Morin et al. 2011; Muppidi et al. 2014 | |
|
| 172 | +| [SAL3](SAL3) | 2 | Burkhardt et al. 2022 | |
|
| 173 | +| [SALL3](SALL3) | 2 | Love et al. 2012 | |
|
| 174 | +| [SAPS2](SAPS2) | 2 | Love et al. 2012 | |
|
| 175 | +| [SBF1](SBF1) | 2 | Love et al. 2012 | |
|
| 176 | +| [SF3B1](SF3B1) | 2 | Love et al. 2012 | |
|
| 177 | +| [SHANK1](SHANK1) | 2 | Love et al. 2012 | |
|
| 178 | +| [SLC29A2](SLC29A2) | 2 | Love et al. 2012 | |
|
| 179 | +| [SNTB2](SNTB2) | 2 | Panea et al. 2019 | |
|
| 180 | +| [SP3](SP3) | 2 | Panea et al. 2019 | |
|
| 181 | +| [SYNCRIP](SYNCRIP) | 2 | Panea et al. 2019 | |
|
| 182 | +| [SYNGAP1](SYNGAP1) | 2 | Love et al. 2012 | |
|
| 183 | +| [TBC1D9B](TBC1D9B) | 2 | Love et al. 2012 | |
|
| 184 | +| [TET2](TET2) | 2 | Albuquerque et al. 2017; Panea et al. 2019 | |
|
| 185 | +| [TIGD6](TIGD6) | 2 | Love et al. 2012 | |
|
| 186 | +| [TOP2A](TOP2A) | 2 | Schmitz et al. 2012 | |
|
| 187 | +| [TPST2](TPST2) | 2 | Love et al. 2012 | |
|
| 188 | +| [TTN](TTN) | 2 | Burkhardt et al. 2022 | |
|
| 189 | +| [VWA7](VWA7) | 2 | Burkhardt et al. 2022 | |
|
| 190 | +| [WDR7](WDR7) | 2 | Panea et al. 2019 | |
|
| 191 | +| [WDR90](WDR90) | 2 | Schmitz et al. 2012 | |
|
| 192 | +| [WHAMM](WHAMM) | 2 | Schmitz et al. 2012 | |
|
| 193 | +| [WNK2](WNK2) | 2 | Panea et al. 2019 | |
|
| 194 | +| [YY1AP1](YY1AP1) | 2 | Schmitz et al. 2012 | |
|
| 195 | +| [ZAN](ZAN) | 2 | Burkhardt et al. 2022 | |
|
| 196 | +| [ZBTB7A](ZBTB7A) | 2 | Burkhardt et al. 2022; Reddy et al. 2017 | |
|
| 197 | +| [ZFP36L1](ZFP36L1) | 2a | Morin et al. 2011; Panea et al. 2019 | |
|
| 198 | +| [ZNF229](ZNF229) | 2 | Love et al. 2012 | |
|
| 199 | +| [ZNF85](ZNF85) | 2 | Burkhardt et al. 2022 | |
|
| 200 | + |
|
| 201 | +# References |
|
| 202 | + |
|
| 203 | +<div id="refs" class="references csl-bib-body hanging-indent"> |
|
| 204 | + |
|
| 205 | +<div id="ref-abateDistinctViralMutational2015a" class="csl-entry"> |
|
| 206 | + |
|
| 207 | +Abate, F., M. Ambrosio, L. Mundo, M. Laginestra, F. Fuligni, M. Rossi, |
|
| 208 | +Sakellarios Zairis, et al. 2015. “Distinct Viral and Mutational Spectrum |
|
| 209 | +of Endemic Burkitt Lymphoma.” *PLoS Pathogens* 11. |
|
| 210 | +<https://doi.org/10.1371/journal.ppat.1005158>. |
|
| 211 | + |
|
| 212 | +</div> |
|
| 213 | + |
|
| 214 | +<div id="ref-albuquerqueEnhancingKnowledgeDiscovery2017a" |
|
| 215 | +class="csl-entry"> |
|
| 216 | + |
|
| 217 | +Albuquerque, Marco A., Bruno M. Grande, Elie J. Ritch, Prasath |
|
| 218 | +Pararajalingam, Selin Jessa, Martin Krzywinski, Jasleen K. Grewal, |
|
| 219 | +Sohrab P. Shah, Paul C. Boutros, and Ryan D. Morin. 2017. “Enhancing |
|
| 220 | +Knowledge Discovery from Cancer Genomics Data with Galaxy.” |
|
| 221 | +*GigaScience* 6 5: 1–13. <https://doi.org/10.1093/gigascience/gix015>. |
|
| 222 | + |
|
| 223 | +</div> |
|
| 224 | + |
|
| 225 | +<div id="ref-arthurGenomewideDiscoverySomatic2018" class="csl-entry"> |
|
| 226 | + |
|
| 227 | +Arthur, Sarah E., Aixiang Jiang, Bruno M. Grande, Miguel Alcaide, Razvan |
|
| 228 | +Cojocaru, Christopher K. Rushton, Anja Mottok, et al. 2018. “Genome-Wide |
|
| 229 | +Discovery of Somatic Regulatory Variants in Diffuse Large <span |
|
| 230 | +class="nocase">B-cell</span> Lymphoma.” *Nature Communications* 9 1: |
|
| 231 | +4001. <https://doi.org/10.1038/s41467-018-06354-3>. |
|
| 232 | + |
|
| 233 | +</div> |
|
| 234 | + |
|
| 235 | +<div id="ref-bohleRoleEarlyBcell2013" class="csl-entry"> |
|
| 236 | + |
|
| 237 | +Bohle, V., C. Döring, M.-L. Hansmann, and R. Küppers. 2013. “Role of |
|
| 238 | +Early <span class="nocase">B-cell</span> Factor 1 EBF1 in Hodgkin |
|
| 239 | +Lymphoma.” *Leukemia* 27 3: 671–79. |
|
| 240 | +<https://doi.org/10.1038/leu.2012.280>. |
|
| 241 | + |
|
| 242 | +</div> |
|
| 243 | + |
|
| 244 | +<div id="ref-burkhardtClinicalRelevanceMolecular2022b" |
|
| 245 | +class="csl-entry"> |
|
| 246 | + |
|
| 247 | +Burkhardt, Birgit, Ulf Michgehl, Jonas Rohde, Tabea Erdmann, Philipp |
|
| 248 | +Berning, Katrin Reutter, Marius Rohde, et al. 2022. “Clinical Relevance |
|
| 249 | +of Molecular Characteristics in Burkitt Lymphoma Differs According to |
|
| 250 | +Age.” *Nature Communications* 13 1: 3881. |
|
| 251 | +<https://doi.org/10.1038/s41467-022-31355-8>. |
|
| 252 | + |
|
| 253 | +</div> |
|
| 254 | + |
|
| 255 | +<div id="ref-chapuyMolecularSubtypesDiffuse2018b" class="csl-entry"> |
|
| 256 | + |
|
| 257 | +Chapuy, Bjoern, Chip Stewart, Andrew J. Dunford, Jaegil Kim, Atanas |
|
| 258 | +Kamburov, Robert A. Redd, Mike S. Lawrence, et al. 2018. “Molecular |
|
| 259 | +Subtypes of Diffuse Large B Cell Lymphoma Are Associated with Distinct |
|
| 260 | +Pathogenic Mechanisms and Outcomes.” *Nature Medicine* 24 5: 679–90. |
|
| 261 | +<https://doi.org/10.1038/s41591-018-0016-8>. |
|
| 262 | + |
|
| 263 | +</div> |
|
| 264 | + |
|
| 265 | +<div id="ref-grandeGenomewideDiscoverySomatic2019" class="csl-entry"> |
|
| 266 | + |
|
| 267 | +Grande, Bruno M., Daniela S. Gerhard, Aixiang Jiang, Nicholas B. Griner, |
|
| 268 | +Jeremy S. Abramson, Thomas B. Alexander, Hilary Allen, et al. 2019. |
|
| 269 | +“Genome-Wide Discovery of Somatic Coding and Noncoding Mutations in |
|
| 270 | +Pediatric Endemic and Sporadic Burkitt Lymphoma.” *Blood* 133 12: |
|
| 271 | +1313–24. <https://doi.org/10.1182/blood-2018-09-871418>. |
|
| 272 | + |
|
| 273 | +</div> |
|
| 274 | + |
|
| 275 | +<div id="ref-hubschmannMutationalMechanismsShaping2021b" |
|
| 276 | +class="csl-entry"> |
|
| 277 | + |
|
| 278 | +Hübschmann, Daniel, Kortine Kleinheinz, Rabea Wagener, Stephan H. |
|
| 279 | +Bernhart, Cristina López, Umut H. Toprak, Stephanie Sungalee, et al. |
|
| 280 | +2021. “Mutational Mechanisms Shaping the Coding and Noncoding Genome of |
|
| 281 | +Germinal Center Derived <span class="nocase">B-cell</span> Lymphomas.” |
|
| 282 | +*Leukemia* 35 7: 2002–16. |
|
| 283 | +<https://doi.org/10.1038/s41375-021-01251-z>. |
|
| 284 | + |
|
| 285 | +</div> |
|
| 286 | + |
|
| 287 | +<div id="ref-johnstonCmycHypermutationBurkitt1992" class="csl-entry"> |
|
| 288 | + |
|
| 289 | +Johnston, J. M., and W. L. Carroll. 1992. “C-Myc Hypermutation in |
|
| 290 | +Burkitt’s Lymphoma.” *Leukemia & Lymphoma* 8 6: 431–39. |
|
| 291 | +<https://doi.org/10.3109/10428199209051025>. |
|
| 292 | + |
|
| 293 | +</div> |
|
| 294 | + |
|
| 295 | +<div id="ref-khodabakhshiRecurrentTargetsAberrant2012" |
|
| 296 | +class="csl-entry"> |
|
| 297 | + |
|
| 298 | +Khodabakhshi, Alireza Hadj, Ryan D. Morin, Anthony P. Fejes, Andrew J. |
|
| 299 | +Mungall, Karen L. Mungall, Madison Bolger-Munro, Nathalie A. Johnson, et |
|
| 300 | +al. 2012. “Recurrent Targets of Aberrant Somatic Hypermutation in |
|
| 301 | +Lymphoma.” *Oncotarget* 3 11: 1308–19. |
|
| 302 | +<https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717795/>. |
|
| 303 | + |
|
| 304 | +</div> |
|
| 305 | + |
|
| 306 | +<div id="ref-krysiakRecurrentSomaticMutations2017b" class="csl-entry"> |
|
| 307 | + |
|
| 308 | +Krysiak, Kilannin, Felicia Gomez, Brian S. White, Matthew Matlock, |
|
| 309 | +Christopher A. Miller, Lee Trani, Catrina C. Fronick, et al. 2017. |
|
| 310 | +“Recurrent Somatic Mutations Affecting <span |
|
| 311 | +class="nocase">B-cell</span> Receptor Signaling Pathway Genes in |
|
| 312 | +Follicular Lymphoma.” *Blood* 129 4: 473–83. |
|
| 313 | +<https://doi.org/10.1182/blood-2016-07-729954>. |
|
| 314 | + |
|
| 315 | +</div> |
|
| 316 | + |
|
| 317 | +<div id="ref-kwanhianMicroRNA142Mutated202012b" class="csl-entry"> |
|
| 318 | + |
|
| 319 | +Kwanhian, Wiyada, Dido Lenze, Julia Alles, Natalie Motsch, Stephanie |
|
| 320 | +Barth, Celina Döll, Jochen Imig, et al. 2012. “MicroRNA-142 Is Mutated |
|
| 321 | +in about 20% of Diffuse Large <span class="nocase">B-cell</span> |
|
| 322 | +Lymphoma.” *Cancer Medicine* 1 2: 141–55. |
|
| 323 | +<https://doi.org/10.1002/cam4.29>. |
|
| 324 | + |
|
| 325 | +</div> |
|
| 326 | + |
|
| 327 | +<div id="ref-lenzOncogenicCARD11Mutations2008" class="csl-entry"> |
|
| 328 | + |
|
| 329 | +Lenz, Georg, R Eric Davis, Vu N Ngo, Lloyd Lam, Thaddeus C George, |
|
| 330 | +George W Wright, Sandeep S Dave, et al. 2008. “Oncogenic CARD11 |
|
| 331 | +Mutations in Human Diffuse Large B Cell Lymphoma.” *Science* 319 5870: |
|
| 332 | +1676–79. |
|
| 333 | + |
|
| 334 | +</div> |
|
| 335 | + |
|
| 336 | +<div id="ref-lohrDiscoveryPrioritizationSomatic2012a" class="csl-entry"> |
|
| 337 | + |
|
| 338 | +Lohr, Jens G., Petar Stojanov, Michael S. Lawrence, Daniel Auclair, |
|
| 339 | +Bjoern Chapuy, Carrie Sougnez, Peter Cruz-Gordillo, et al. 2012. |
|
| 340 | +“Discovery and Prioritization of Somatic Mutations in Diffuse Large |
|
| 341 | +<span class="nocase">B-cell</span> Lymphoma DLBCL by Whole-Exome |
|
| 342 | +Sequencing.” *Proceedings of the National Academy of Sciences of the |
|
| 343 | +United States of America* 109 10: 3879–84. |
|
| 344 | +<https://doi.org/10.1073/pnas.1121343109>. |
|
| 345 | + |
|
| 346 | +</div> |
|
| 347 | + |
|
| 348 | +<div id="ref-loveGeneticLandscapeMutations2012" class="csl-entry"> |
|
| 349 | + |
|
| 350 | +Love, Cassandra, Zhen Sun, Dereje Jima, Guojie Li, Jenny Zhang, Rodney |
|
| 351 | +Miles, Kristy L. Richards, et al. 2012. “The Genetic Landscape of |
|
| 352 | +Mutations in Burkitt Lymphoma.” *Nature Genetics* 44 12: 1321–25. |
|
| 353 | +<https://doi.org/10.1038/ng.2468>. |
|
| 354 | + |
|
| 355 | +</div> |
|
| 356 | + |
|
| 357 | +<div id="ref-morinSomaticMutationsAltering2010a" class="csl-entry"> |
|
| 358 | + |
|
| 359 | +Morin, Ryan D., Nathalie A. Johnson, Tesa M. Severson, Andrew J. |
|
| 360 | +Mungall, Jianghong An, Rodrigo Goya, Jessica E. Paul, et al. 2010. |
|
| 361 | +“Somatic Mutations Altering EZH2 Tyr641 in Follicular and Diffuse |
|
| 362 | +Large <span class="nocase">B-cell</span> Lymphomas of Germinal-Center |
|
| 363 | +Origin.” *Nature Genetics* 42 2: 181–85. |
|
| 364 | +<https://doi.org/10.1038/ng.518>. |
|
| 365 | + |
|
| 366 | +</div> |
|
| 367 | + |
|
| 368 | +<div id="ref-morinFrequentMutationHistonemodifying2011" |
|
| 369 | +class="csl-entry"> |
|
| 370 | + |
|
| 371 | +Morin, Ryan D., Maria Mendez-Lago, Andrew J. Mungall, Rodrigo Goya, |
|
| 372 | +Karen L. Mungall, Richard D. Corbett, Nathalie A. Johnson, et al. 2011. |
|
| 373 | +“Frequent Mutation of Histone-Modifying Genes in Non-Hodgkin Lymphoma.” |
|
| 374 | +*Nature* 476 7360: 298–303. <https://doi.org/10.1038/nature10351>. |
|
| 375 | + |
|
| 376 | +</div> |
|
| 377 | + |
|
| 378 | +<div id="ref-morinMutationalStructuralAnalysis2013" class="csl-entry"> |
|
| 379 | + |
|
| 380 | +Morin, Ryan D., Karen Mungall, Erin Pleasance, Andrew J. Mungall, |
|
| 381 | +Rodrigo Goya, Ryan D. Huff, David W. Scott, et al. 2013. “Mutational and |
|
| 382 | +Structural Analysis of Diffuse Large <span class="nocase">B-cell</span> |
|
| 383 | +Lymphoma Using Whole-Genome Sequencing.” *Blood* 122 7: 1256–65. |
|
| 384 | +<https://doi.org/10.1182/blood-2013-02-483727>. |
|
| 385 | + |
|
| 386 | +</div> |
|
| 387 | + |
|
| 388 | +<div id="ref-muppidiLossSignalingGa132014b" class="csl-entry"> |
|
| 389 | + |
|
| 390 | +Muppidi, J., R. Schmitz, Jesse A. Green, Jesse A. Green, Wenming Xiao, |
|
| 391 | +Adrien B. Larsen, S. Braun, et al. 2014. “Loss of Signaling via Gα13 in |
|
| 392 | +Germinal Center B Cell-Derived Lymphoma.” *Nature* 516: 254–58. |
|
| 393 | +<https://doi.org/10.1038/nature13765>. |
|
| 394 | + |
|
| 395 | +</div> |
|
| 396 | + |
|
| 397 | +<div id="ref-paneaWholeGenomeLandscape2019" class="csl-entry"> |
|
| 398 | + |
|
| 399 | +Panea, R., C. Love, Jennifer R. Shingleton, Anupama Reddy, J. Bailey, A. |
|
| 400 | +Moormann, J. Otieno, et al. 2019. “The Whole Genome Landscape of Burkitt |
|
| 401 | +Lymphoma Subtypes.” *Blood*. <https://doi.org/10.1182/blood.2019001880>. |
|
| 402 | + |
|
| 403 | +</div> |
|
| 404 | + |
|
| 405 | +<div id="ref-pasqualucciInactivatingMutationsAcetyltransferase2011a" |
|
| 406 | +class="csl-entry"> |
|
| 407 | + |
|
| 408 | +Pasqualucci, Laura, David Dominguez-Sola, Annalisa Chiarenza, Giulia |
|
| 409 | +Fabbri, Adina Grunn, Vladimir Trifonov, Lawryn H. Kasper, et al. 2011. |
|
| 410 | +“Inactivating Mutations of Acetyltransferase Genes in <span |
|
| 411 | +class="nocase">B-cell</span> Lymphoma.” *Nature* 471 7337: 189–95. |
|
| 412 | +<https://doi.org/10.1038/nature09730>. |
|
| 413 | + |
|
| 414 | +</div> |
|
| 415 | + |
|
| 416 | +<div id="ref-pasqualucciAnalysisCodingGenome2011" class="csl-entry"> |
|
| 417 | + |
|
| 418 | +Pasqualucci, Laura, Vladimir Trifonov, Giulia Fabbri, Jing Ma, Davide |
|
| 419 | +Rossi, Annalisa Chiarenza, Victoria A. Wells, et al. 2011. “Analysis of |
|
| 420 | +the Coding Genome of Diffuse Large <span class="nocase">B-cell</span> |
|
| 421 | +Lymphoma.” *Nature Genetics* 43 9: 830–37. |
|
| 422 | +<https://doi.org/10.1038/ng.892>. |
|
| 423 | + |
|
| 424 | +</div> |
|
| 425 | + |
|
| 426 | +<div id="ref-pasqualucciHypermutationMultipleProtooncogenes2001a" |
|
| 427 | +class="csl-entry"> |
|
| 428 | + |
|
| 429 | +Pasqualucci, L., P. Neumeister, T. Goossens, G. Nanjangud, R. S. |
|
| 430 | +Chaganti, R. Küppers, and R. Dalla-Favera. 2001. “Hypermutation of |
|
| 431 | +Multiple Proto-Oncogenes in <span class="nocase">B-cell</span> Diffuse |
|
| 432 | +Large-Cell Lymphomas.” *Nature* 412 6844: 341–46. |
|
| 433 | +<https://doi.org/10.1038/35085588>. |
|
| 434 | + |
|
| 435 | +</div> |
|
| 436 | + |
|
| 437 | +<div id="ref-reddyGeneticFunctionalDrivers2017" class="csl-entry"> |
|
| 438 | + |
|
| 439 | +Reddy, Anupama, Jenny Zhang, Nicholas S Davis, Andrea B Moffitt, |
|
| 440 | +Cassandra L Love, Alexander Waldrop, Sirpa Leppa, et al. 2017. “Genetic |
|
| 441 | +and Functional Drivers of Diffuse Large B Cell Lymphoma.” *Cell* 171 |
|
| 442 | +2: 481–494.e15. |
|
| 443 | + |
|
| 444 | +</div> |
|
| 445 | + |
|
| 446 | +<div id="ref-richterRecurrentMutationID32012a" class="csl-entry"> |
|
| 447 | + |
|
| 448 | +Richter, Julia, Matthias Schlesner, Steve Hoffmann, Markus Kreuz, Ellen |
|
| 449 | +Leich, Birgit Burkhardt, Maciej Rosolowski, et al. 2012. “Recurrent |
|
| 450 | +Mutation of the ID3 Gene in Burkitt Lymphoma Identified by Integrated |
|
| 451 | +Genome, Exome and Transcriptome Sequencing.” *Nature Genetics* 44 12: |
|
| 452 | +1316–20. <https://doi.org/10.1038/ng.2469>. |
|
| 453 | + |
|
| 454 | +</div> |
|
| 455 | + |
|
| 456 | +<div id="ref-russler-germainMutationsAssociatedProgression2023b" |
|
| 457 | +class="csl-entry"> |
|
| 458 | + |
|
| 459 | +Russler-Germain, David A., Kilannin Krysiak, Cody A. Ramirez, Matthew |
|
| 460 | +Mosior, Marcus P. Watkins, Felicia Gomez, Zachary L. Skidmore, et al. |
|
| 461 | +2023. “Mutations Associated with Progression in Follicular Lymphoma |
|
| 462 | +Predict Inferior Outcomes at Diagnosis: Alliance A151303.” *Blood |
|
| 463 | +Advances* 7: 5524–39. |
|
| 464 | +<https://doi.org/10.1182/bloodadvances.2023010779>. |
|
| 465 | + |
|
| 466 | +</div> |
|
| 467 | + |
|
| 468 | +<div id="ref-schmitzGeneticsPathogenesisDiffuse2018a" class="csl-entry"> |
|
| 469 | + |
|
| 470 | +Schmitz, Roland, George W. Wright, Da Wei Huang, Calvin A. Johnson, |
|
| 471 | +James D. Phelan, James Q. Wang, Sandrine Roulland, et al. 2018. |
|
| 472 | +“Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma.” *The New |
|
| 473 | +England Journal of Medicine* 378 15: 1396–1407. |
|
| 474 | +<https://doi.org/10.1056/NEJMoa1801445>. |
|
| 475 | + |
|
| 476 | +</div> |
|
| 477 | + |
|
| 478 | +<div id="ref-schmitzBurkittLymphomaPathogenesis2012" class="csl-entry"> |
|
| 479 | + |
|
| 480 | +Schmitz, Roland, Ryan M. Young, Michele Ceribelli, Sameer Jhavar, |
|
| 481 | +Wenming Xiao, Meili Zhang, George Wright, et al. 2012. “Burkitt Lymphoma |
|
| 482 | +Pathogenesis and Therapeutic Targets from Structural and Functional |
|
| 483 | +Genomics.” *Nature* 490 7418: 116–20. |
|
| 484 | +<https://doi.org/10.1038/nature11378>. |
|
| 485 | + |
|
| 486 | +</div> |
|
| 487 | + |
|
| 488 | +<div id="ref-tanakaFrequentIncidenceSomatic1992" class="csl-entry"> |
|
| 489 | + |
|
| 490 | +Tanaka, S., D. C. Louie, J. A. Kant, and J. C. Reed. 1992. “Frequent |
|
| 491 | +Incidence of Somatic Mutations in Translocated BCL2 Oncogenes of |
|
| 492 | +Non-Hodgkin’s Lymphomas.” *Blood* 79 1: 229–37. |
|
| 493 | + |
|
| 494 | +</div> |
|
| 495 | + |
|
| 496 | +<div id="ref-thomasGeneticSubgroupsInform2023" class="csl-entry"> |
|
| 497 | + |
|
| 498 | +Thomas, Nicole, Kostiantyn Dreval, Daniela S. Gerhard, Laura K. Hilton, |
|
| 499 | +Jeremy S. Abramson, Richard F. Ambinder, Stefan Barta, et al. 2023. |
|
| 500 | +“Genetic Subgroups Inform on Pathobiology in Adult and Pediatric Burkitt |
|
| 501 | +Lymphoma.” *Blood* 141 8: 904–16. |
|
| 502 | +<https://doi.org/10.1182/blood.2022016534>. |
|
| 503 | + |
|
| 504 | +</div> |
|
| 505 | + |
|
| 506 | +<div id="ref-tiacciBRAFMutationsHairycell2011a" class="csl-entry"> |
|
| 507 | + |
|
| 508 | +Tiacci, Enrico, Vladimir Trifonov, Gianluca Schiavoni, Antony Holmes, |
|
| 509 | +Wolfgang Kern, Maria Paola Martelli, Alessandra Pucciarini, et al. 2011. |
|
| 510 | +“BRAF Mutations in Hairy-Cell Leukemia.” *The New England Journal of |
|
| 511 | +Medicine* 364 24: 2305–15. <https://doi.org/10.1056/NEJMoa1014209>. |
|
| 512 | + |
|
| 513 | +</div> |
|
| 514 | + |
|
| 515 | +<div id="ref-troenNOTCH2MutationsMarginal2008" class="csl-entry"> |
|
| 516 | + |
|
| 517 | +Trøen, Gunhild, Iwona Wlodarska, Abdirashid Warsame, Silvia Hernández |
|
| 518 | +Llodrà, Christiane De Wolf-Peeters, and Jan Delabie. 2008. “NOTCH2 |
|
| 519 | +Mutations in Marginal Zone Lymphoma.” *Haematologica* 93 7: 1107–9. |
|
| 520 | +<https://doi.org/10.3324/haematol.11635>. |
|
| 521 | + |
|
| 522 | +</div> |
|
| 523 | + |
|
| 524 | +<div id="ref-wildaInactivationARFMDM2p53Pathway2004" class="csl-entry"> |
|
| 525 | + |
|
| 526 | +Wilda, M., J. Bruch, L. Harder, D. Rawer, A. Reiter, A. Borkhardt, and |
|
| 527 | +W. Woessmann. 2004. “Inactivation of the <span |
|
| 528 | +class="nocase">ARF-MDM-2-p53</span> Pathway in Sporadic Burkitt’s |
|
| 529 | +Lymphoma in Children.” *Leukemia* 18 3: 584–88. |
|
| 530 | +<https://doi.org/10.1038/sj.leu.2403254>. |
|
| 531 | + |
|
| 532 | +</div> |
|
| 533 | + |
|
| 534 | +<div id="ref-zhangGeneticHeterogeneityDiffuse2013" class="csl-entry"> |
|
| 535 | + |
|
| 536 | +Zhang, Jenny, Vladimir Grubor, Cassandra L Love, Anjishnu Banerjee, |
|
| 537 | +Kristy L Richards, Piotr A Mieczkowski, Cherie Dunphy, et al. 2013. |
|
| 538 | +“Genetic Heterogeneity of Diffuse Large <span |
|
| 539 | +class="nocase">B-cell</span> Lymphoma.” January. |
|
| 540 | + |
|
| 541 | +</div> |
|
| 542 | + |
|
| 543 | +<div id="ref-zhouSporadicEndemicBurkitt2019" class="csl-entry"> |
|
| 544 | + |
|
| 545 | +Zhou, Peixun, Alex E. Blain, Alexander M. Newman, Masood Zaka, George |
|
| 546 | +Chagaluka, Filbert R. Adlar, Ugonna T. Offor, et al. 2019. “Sporadic and |
|
| 547 | +Endemic Burkitt Lymphoma Have Frequent FOXO1 Mutations but Distinct |
|
| 548 | +Hotspots in the AKT Recognition Motif.” *Blood Advances* 3 14: |
|
| 549 | +2118–27. <https://doi.org/10.1182/bloodadvances.2018029546>. |
|
| 550 | + |
|
| 551 | +</div> |
|
| 552 | + |
|
| 553 | +</div> |