ARID1B.md
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# ARID1B
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+<<Warn("The variants reported in this gene in DLBCL failed QC")>>
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+
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## History
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-Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.<sup>1</sup>
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```mermaid
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%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
GNAS.md
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# GNAS
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+<<Warn("The variants reported in this gene in DLBCL failed QC")>>
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+
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## History
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```mermaid
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%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
LIN54.md
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# LIN54
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+<<Warn("The variants reported in this gene in DLBCL failed QC")>>
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+
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## History
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```mermaid
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%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
MAP4K4.md
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# MAP4K4
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+<<Warn("The variants reported in this gene in DLBCL failed QC")>>
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+
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## History
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```mermaid
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%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
MCL1.md
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# MCL1
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+<<Warn("The variants reported in this gene in DLBCL failed QC")>>
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+
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## Overview
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MCL1 (Myeloid Cell Leukemia 1) is a member of the BCL2 family of proteins that play a critical role in inhibiting apoptosis. It is frequently overexpressed and sometimes mutated in DLBCL.<sup>1,2</sup> Recurrent chromosomal gains and amplifications of the MCL1 locus occur are frequent in ABC-DLBCLs.<sup>1</sup> MCL1 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) affected by aberrant somatic hypermutation in B-cell lymphomas, which complicates the interpretation of mutations at this locus.
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MSH2.md
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# MSH2
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+<<Warn("The variants reported in this gene in DLBCL failed QC")>>
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+
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## History
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```mermaid
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%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
MYB.md
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# MYB
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+<<Warn("The variants reported in this gene in DLBCL failed QC")>>
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+
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## History
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```mermaid
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%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
NCOR1.md
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# NCOR1
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+<<Warn("The variants reported in this gene in DLBCL failed QC")>>
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+
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## History
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```mermaid
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%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
NFKB2.md
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# NFKB2
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+<<Warn("The variants reported in this gene in DLBCL failed QC")>>
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+
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## History
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```mermaid
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%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
PHF6.md
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# PHF6
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+<<Warn("The variants reported in this gene in DLBCL failed QC")>>
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+
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## History
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```mermaid
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%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
PIK3CD.md
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# PIK3CD
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+<<Warn("The variants reported in this gene in DLBCL failed QC")>>
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+
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## History
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```mermaid
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%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
PTPRK.md
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# PTPRK
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+<<Warn("The variants reported in this gene in DLBCL failed QC")>>
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+
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## History
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```mermaid
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%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
ZFAT.md
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# ZFAT
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+<<Warn("The variants reported in this gene in DLBCL failed QC")>>
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+
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## History
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```mermaid
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%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%