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BCOR.md
| ... | ... | @@ -20,24 +20,15 @@ BCOR acts as a co-repressor of BCL6, and mutations in BCOR could impair its bind |
| 20 | 20 | |
| 21 | 21 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 22 | 22 | |
| 23 | -|Entity|source |frequency (%)| |
|
| 24 | -|:------:|:--------------:|:-------------:| |
|
| 25 | -|DLBCL |GAMBL genomes |3.82 | |
|
| 26 | -|DLBCL |Schmitz cohort|7.66 | |
|
| 27 | -|DLBCL |Reddy cohort |2.50 | |
|
| 28 | -|DLBCL |Chapuy cohort |2.56 | |
|
| 29 | -|MCL |GAMBL genomes |3.79 | |
|
| 30 | - |
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| 31 | -## Mutation pattern and selective pressure estimates |
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| 32 | - |
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| 33 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 34 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 35 | -|BL |No |No |1.341 |0 | |
|
| 36 | -|DLBCL |No |No |2.471 |0 | |
|
| 37 | -|FL |No |No |1.743 |0 | |
|
| 23 | +### DLBCL |
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| 24 | +[[include:tables/DLBCL_BCOR]] |
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| 38 | 25 | |
| 26 | +### MCL |
|
| 27 | +[[include:tables/MCL_BCOR]] |
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| 39 | 28 | |
| 29 | +## Mutation pattern and selective pressure estimates |
|
| 40 | 30 | |
| 31 | +[[include:tables/dnds_BCOR]] |
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| 41 | 32 | |
| 42 | 33 | ## BCOR Hotspots |
| 43 | 34 |