ABI3BP.md
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-# [ABI3BP]
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+# ABI3BP
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-## Mutation tier
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+## Relevance tier by entity
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|Entity|Tier|Description |
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|:------:|:----:|-----------------------------------------|
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|DLBCL |2 |relevance in DLBCL not firmly established|
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-## Mutation incidence
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+
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+## Mutation incidence in large patient cohorts (GAMBL reanalysis)
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|Entity|source |frequency (%)|
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|:------:|:--------------:|:-------------:|
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|DLBCL |Reddy cohort |1.80 |
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|DLBCL |Chapuy cohort |2.99 |
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-## Mutation pattern
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+## Mutation pattern and selective pressure estimates
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|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)|
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|:------:|:----:|:---------------------:|:----------------:|:----------------:|