ITPKB.md
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-# [ITPKB]
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+ITPKB is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) affected by aberrant somatic hypermutation in B-cell lymphomas, which complicates the interpretation of mutations at this locus.
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## Mutation tier
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|Entity|Tier|Description |
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|:------:|:----:|--------------------------|
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-|DLBCL |1 |high-confidence DLBCL gene|
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-|FL |1 |high-confidence FL gene |
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+|DLBCL |1-a |high-confidence DLBCL gene, hypermutated|
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+|FL |1-a |high-confidence FL gene, hypermutated |
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## Mutation incidence
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|Entity|source |frequency (%)|