Changes in 8864697: reorg

				Template.md
			
          @@ -1,62 +0,0 @@

          ----

          -bibliography: 'morinlab.bib'

          -csl: 'NLM.csl'

          -link-citations: true

          -nocite: |

          -  @balSuperenhancerHypermutationAlters2022, @tanakaFrequentIncidenceSomatic1992, @sarkozyMutationalLandscapeGray2021, @burkhardtClinicalRelevanceMolecular2022

          ----

          -

          -

          -[[_TOC_]]

          -

          -## Overview

          -

          -## Relevance tier by entity

          -

          -*test*

          -

          -[[include:Template_Relevance.md]]

          -

          -## Warnings

          -

          -*may not exist*

          -

          -## Mutation incidence from meta-analysis

          -*sub headings per file here unless there is just one*

          -

          -### DLBCL

          -[[include:tables/DLBCL_BCL2.md]]

          -

          -### FL

          -[[include:tables/FL_BCL2.md]]

          -

          -### BL

          -[[include:tables/BL_BCL2.md]]

          -

          -## Mutation pattern and selective pressure estimates

          -

          -[[include:tables/dnds_BCL2.md]]

          -

          -## aSHM regions

          -

          -*section will only exist for certain genes*

          -

          -|chr_name|hg19_start|hg19_end|region|regulatory_comment|

          -|:--------:|:----------:|:--------:|:--------:|:------------------:|

          -|chr6    |90981034  |91016134|[TSS](https://genome.ucsc.edu/s/rdmorin/GAMBL%20hg19?position=chr6%3A90981034%2D91016134)|NA|

          -

          -## Hotspots

          -

          -*section will only exist for certain genes*

          -

          -[[include:Template_Browser.md]]

          -

          -## Expression

          -

          -![](images/gene_expression/ZNF296_by_pathology.svg)

          -

          -[[include:Template_History.md]]

          -

          -## References

          -

          -

				Template_Browser.md
			
          @@ -1,11 +0,0 @@

          -## Browse mutations

          -

          -### Protein

          -View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/BCL2_protein.html)  or [hg38](https://morinlab.github.io/LLMPP/GAMBL/BCL2_protein_hg38.html)

          -

          -![](images/proteinpaint/BCL2_NM_000633.svg)

          -

          -### Genome

          -View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/BCL2.html)  or [hg38](https://morinlab.github.io/LLMPP/GAMBL/BCL2_hg38.html)

          -

          -![](images/proteinpaint/BCL2.svg)

				Template_Expression.md
			
          @@ -1,2 +0,0 @@

          -## Expression

          -![](images/gene_expression/BCL2_by_pathology.svg)

				Template_History.md
			
          @@ -1,11 +0,0 @@

          -## History

          -

          -```mermaid

          -%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%

          -timeline

          -    title Publication timing

          -      1992-01-01 : Tanaka : DLBCL

          -      2011-07-27 : Morin : FL

          -      2021-04-01 : Sarkozy : PMBL

          -      2022-07-06 : Burkhardt : BL

          -```

          \ No newline at end of file

				Template_Hotspots.md
			
          @@ -1,14 +0,0 @@

          -## Hotspots

          -

          -| Chromosome |Coordinate (hg19) | ref>alt | HGVSp | 

          - | :---:| :---: | :--: | :---: |

          -| chr18 | 60985854 | T>C | M16V |

          -| chr18 | 60985854 | T>A | M16L |

          -| chr18 | 60985853 | A>T | M16K |

          -| chr18 | 60985852 | C>T | M16I |

          -| chr18 | 60985849 | C>G | K17N |

          -| chr18 | 60985842 | G>A | H20Y |

          -| chr18 | 60985840 | A>C | H20Q |

          -| chr18 | 60985838 | T>G | Y21S |

          -| chr18 | 60985835 | T>C | K22R |

          -| chr18 | 60985834 | CT>TC | K22R |

				Template_Overview.md
			
          @@ -1,5 +0,0 @@

          -## Overview

          -

          -BCL2 mutations are frequently found in DLBCL, particularly in the germinal center B-cell (GCB) subtype, and are often located in the flexible loop domain and outside the BCL2-homology domains. 

          -These mutations are caused by the somatic hypermutation process. The presence of these mutations are strongly correlated with the presence of a translocation between BCL2 and one of the immunoglobulin loci.

          -Although missense mutations may not be under positive selective pressure in the context of lymphomagenesis, some of these mutations may interfere with the function of BCL2 antagonists.

				Template_Relevance.md
			
          @@ -1,9 +0,0 @@

          -

          -# Test

          -

          -|Entity|Tier|Description                           |

          -|:------:|:----:|--------------------------------------|

          -|![DLBCL](images/icons/tables/DLBCL_tier1.png) |[1](DLBCL_genes#tier-1-dlbcl-genes)|high-confidence DLBCL gene    |

          -|![FL](images/icons/tables/FL_tier1.png)    |1   |high-confidence FL gene|

          -|![PMBL](images/icons/PMtables/BL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established|

          -|![BL](images/icons/tables/BL_tier2.png)    |[2](BL_genes#tier-2-bl-genes)   |relevance in BL not firmly established|

				Template_aSHM.md
			
          @@ -1,6 +0,0 @@

          -## aSHM regions

          -

          -|chr_name|hg19_start|hg19_end|region                                                                                       |regulatory_comment|

          -|:--------:|:----------:|:--------:|:---------------------------------------------------------------------------------------------:|:------------------:|

          -|chr18   |60796984  |60814103|[intron](https://genome.ucsc.edu/s/rdmorin/GAMBL%20hg19?position=chr18%3A60796984%2D60814103)|strong_enhancer   |

          -|chr18   |60982728  |60988342|[TSS](https://genome.ucsc.edu/s/rdmorin/GAMBL%20hg19?position=chr18%3A60982728%2D60988342)   |active_promoter   |

				templates/Template.md
			
          @@ -0,0 +1,62 @@

          +---

          +bibliography: 'morinlab.bib'

          +csl: 'NLM.csl'

          +link-citations: true

          +nocite: |

          +  @balSuperenhancerHypermutationAlters2022, @tanakaFrequentIncidenceSomatic1992, @sarkozyMutationalLandscapeGray2021, @burkhardtClinicalRelevanceMolecular2022

          +---

          +

          +

          +[[_TOC_]]

          +

          +## Overview

          +

          +## Relevance tier by entity

          +

          +*test*

          +

          +[[include:Template_Relevance.md]]

          +

          +## Warnings

          +

          +*may not exist*

          +

          +## Mutation incidence from meta-analysis

          +*sub headings per file here unless there is just one*

          +

          +### DLBCL

          +[[include:tables/DLBCL_BCL2.md]]

          +

          +### FL

          +[[include:tables/FL_BCL2.md]]

          +

          +### BL

          +[[include:tables/BL_BCL2.md]]

          +

          +## Mutation pattern and selective pressure estimates

          +

          +[[include:tables/dnds_BCL2.md]]

          +

          +## aSHM regions

          +

          +*section will only exist for certain genes*

          +

          +|chr_name|hg19_start|hg19_end|region|regulatory_comment|

          +|:--------:|:----------:|:--------:|:--------:|:------------------:|

          +|chr6    |90981034  |91016134|[TSS](https://genome.ucsc.edu/s/rdmorin/GAMBL%20hg19?position=chr6%3A90981034%2D91016134)|NA|

          +

          +## Hotspots

          +

          +*section will only exist for certain genes*

          +

          +[[include:Template_Browser.md]]

          +

          +## Expression

          +

          +![](images/gene_expression/ZNF296_by_pathology.svg)

          +

          +[[include:Template_History.md]]

          +

          +## References

          +

          +

				templates/Template_Browser.md
			
          @@ -0,0 +1,11 @@

          +## Browse mutations

          +

          +### Protein

          +View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/BCL2_protein.html)  or [hg38](https://morinlab.github.io/LLMPP/GAMBL/BCL2_protein_hg38.html)

          +

          +![](images/proteinpaint/BCL2_NM_000633.svg)

          +

          +### Genome

          +View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/BCL2.html)  or [hg38](https://morinlab.github.io/LLMPP/GAMBL/BCL2_hg38.html)

          +

          +![](images/proteinpaint/BCL2.svg)

				templates/Template_Expression.md
			
          @@ -0,0 +1,2 @@

          +## Expression

          +![](images/gene_expression/BCL2_by_pathology.svg)

				templates/Template_History.md
			
          @@ -0,0 +1,11 @@

          +## History

          +

          +```mermaid

          +%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%

          +timeline

          +    title Publication timing

          +      1992-01-01 : Tanaka : DLBCL

          +      2011-07-27 : Morin : FL

          +      2021-04-01 : Sarkozy : PMBL

          +      2022-07-06 : Burkhardt : BL

          +```

          \ No newline at end of file

				templates/Template_Hotspots.md
			
          @@ -0,0 +1,14 @@

          +## Hotspots

          +

          +| Chromosome |Coordinate (hg19) | ref>alt | HGVSp | 

          + | :---:| :---: | :--: | :---: |

          +| chr18 | 60985854 | T>C | M16V |

          +| chr18 | 60985854 | T>A | M16L |

          +| chr18 | 60985853 | A>T | M16K |

          +| chr18 | 60985852 | C>T | M16I |

          +| chr18 | 60985849 | C>G | K17N |

          +| chr18 | 60985842 | G>A | H20Y |

          +| chr18 | 60985840 | A>C | H20Q |

          +| chr18 | 60985838 | T>G | Y21S |

          +| chr18 | 60985835 | T>C | K22R |

          +| chr18 | 60985834 | CT>TC | K22R |

				templates/Template_Overview.md
			
          @@ -0,0 +1,5 @@

          +## Overview

          +

          +BCL2 mutations are frequently found in DLBCL, particularly in the germinal center B-cell (GCB) subtype, and are often located in the flexible loop domain and outside the BCL2-homology domains. 

          +These mutations are caused by the somatic hypermutation process. The presence of these mutations are strongly correlated with the presence of a translocation between BCL2 and one of the immunoglobulin loci.

          +Although missense mutations may not be under positive selective pressure in the context of lymphomagenesis, some of these mutations may interfere with the function of BCL2 antagonists.

				templates/Template_Relevance.md
			
          @@ -0,0 +1,9 @@

          +

          +# Test

          +

          +|Entity|Tier|Description                           |

          +|:------:|:----:|--------------------------------------|

          +|![DLBCL](images/icons/tables/DLBCL_tier1.png) |[1](DLBCL_genes#tier-1-dlbcl-genes)|high-confidence DLBCL gene    |

          +|![FL](images/icons/tables/FL_tier1.png)    |1   |high-confidence FL gene|

          +|![PMBL](images/icons/PMtables/BL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established|

          +|![BL](images/icons/tables/BL_tier2.png)    |[2](BL_genes#tier-2-bl-genes)   |relevance in BL not firmly established|

				templates/Template_aSHM.md
			
          @@ -0,0 +1,6 @@

          +## aSHM regions

          +

          +|chr_name|hg19_start|hg19_end|region                                                                                       |regulatory_comment|

          +|:--------:|:----------:|:--------:|:---------------------------------------------------------------------------------------------:|:------------------:|

          +|chr18   |60796984  |60814103|[intron](https://genome.ucsc.edu/s/rdmorin/GAMBL%20hg19?position=chr18%3A60796984%2D60814103)|strong_enhancer   |

          +|chr18   |60982728  |60988342|[TSS](https://genome.ucsc.edu/s/rdmorin/GAMBL%20hg19?position=chr18%3A60982728%2D60988342)   |active_promoter   |

...	...	@@ -1,62 +0,0 @@
1		----
2		-bibliography: 'morinlab.bib'
3		-csl: 'NLM.csl'
4		-link-citations: true
5		-nocite: \|
6		- @balSuperenhancerHypermutationAlters2022, @tanakaFrequentIncidenceSomatic1992, @sarkozyMutationalLandscapeGray2021, @burkhardtClinicalRelevanceMolecular2022
7		----
8		-
9		-
10		-[[_TOC_]]
11		-
12		-## Overview
13		-
14		-## Relevance tier by entity
15		-
16		-test
17		-
18		-[[include:Template_Relevance.md]]
19		-
20		-## Warnings
21		-
22		-may not exist
23		-
24		-## Mutation incidence from meta-analysis
25		-sub headings per file here unless there is just one
26		-
27		-### DLBCL
28		-[[include:tables/DLBCL_BCL2.md]]
29		-
30		-### FL
31		-[[include:tables/FL_BCL2.md]]
32		-
33		-### BL
34		-[[include:tables/BL_BCL2.md]]
35		-
36		-## Mutation pattern and selective pressure estimates
37		-
38		-[[include:tables/dnds_BCL2.md]]
39		-
40		-## aSHM regions
41		-
42		-section will only exist for certain genes
43		-
44		-\|chr_name\|hg19_start\|hg19_end\|region\|regulatory_comment\|
45		-\|:--------:\|:----------:\|:--------:\|:--------:\|:------------------:\|
46		-\|chr6 \|90981034 \|91016134\|[TSS](https://genome.ucsc.edu/s/rdmorin/GAMBL%20hg19?position=chr6%3A90981034%2D91016134)\|NA\|
47		-
48		-## Hotspots
49		-
50		-section will only exist for certain genes
51		-
52		-[[include:Template_Browser.md]]
53		-
54		-## Expression
55		-
56		-![](images/gene_expression/ZNF296_by_pathology.svg)
57		-
58		-[[include:Template_History.md]]
59		-
60		-## References
61		-
62		-

...	...	@@ -1,11 +0,0 @@
1		-## Browse mutations
2		-
3		-### Protein
4		-View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/BCL2_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/BCL2_protein_hg38.html)
5		-
6		-![](images/proteinpaint/BCL2_NM_000633.svg)
7		-
8		-### Genome
9		-View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/BCL2.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/BCL2_hg38.html)
10		-
11		-![](images/proteinpaint/BCL2.svg)

...	...	@@ -1,2 +0,0 @@
1		-## Expression
2		-![](images/gene_expression/BCL2_by_pathology.svg)

...	...	@@ -1,11 +0,0 @@
1		-## History
2		-
3		-```mermaid
4		-%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
5		-timeline
6		- title Publication timing
7		- 1992-01-01 : Tanaka : DLBCL
8		- 2011-07-27 : Morin : FL
9		- 2021-04-01 : Sarkozy : PMBL
10		- 2022-07-06 : Burkhardt : BL
11		-```
...	...	\ No newline at end of file

...	...	@@ -1,14 +0,0 @@
1		-## Hotspots
2		-
3		-\| Chromosome \|Coordinate (hg19) \| ref>alt \| HGVSp \|
4		- \| :---:\| :---: \| :--: \| :---: \|
5		-\| chr18 \| 60985854 \| T>C \| M16V \|
6		-\| chr18 \| 60985854 \| T>A \| M16L \|
7		-\| chr18 \| 60985853 \| A>T \| M16K \|
8		-\| chr18 \| 60985852 \| C>T \| M16I \|
9		-\| chr18 \| 60985849 \| C>G \| K17N \|
10		-\| chr18 \| 60985842 \| G>A \| H20Y \|
11		-\| chr18 \| 60985840 \| A>C \| H20Q \|
12		-\| chr18 \| 60985838 \| T>G \| Y21S \|
13		-\| chr18 \| 60985835 \| T>C \| K22R \|
14		-\| chr18 \| 60985834 \| CT>TC \| K22R \|

...	...	@@ -1,5 +0,0 @@
1		-## Overview
2		-
3		-BCL2 mutations are frequently found in DLBCL, particularly in the germinal center B-cell (GCB) subtype, and are often located in the flexible loop domain and outside the BCL2-homology domains.
4		-These mutations are caused by the somatic hypermutation process. The presence of these mutations are strongly correlated with the presence of a translocation between BCL2 and one of the immunoglobulin loci.
5		-Although missense mutations may not be under positive selective pressure in the context of lymphomagenesis, some of these mutations may interfere with the function of BCL2 antagonists.

...	...	@@ -1,9 +0,0 @@
1		-
2		-# Test
3		-
4		-\|Entity\|Tier\|Description \|
5		-\|:------:\|:----:\|--------------------------------------\|
6		-\|![DLBCL](images/icons/tables/DLBCL_tier1.png) \|[1](DLBCL_genes#tier-1-dlbcl-genes)\|high-confidence DLBCL gene \|
7		-\|![FL](images/icons/tables/FL_tier1.png) \|1 \|high-confidence FL gene\|
8		-\|![PMBL](images/icons/PMtables/BL_tier2.png)\|2\|relevance in PMBL/cHL/GZL not firmly established\|
9		-\|![BL](images/icons/tables/BL_tier2.png) \|[2](BL_genes#tier-2-bl-genes) \|relevance in BL not firmly established\|

...	...	@@ -1,6 +0,0 @@
1		-## aSHM regions
2		-
3		-\|chr_name\|hg19_start\|hg19_end\|region \|regulatory_comment\|
4		-\|:--------:\|:----------:\|:--------:\|:---------------------------------------------------------------------------------------------:\|:------------------:\|
5		-\|chr18 \|60796984 \|60814103\|[intron](https://genome.ucsc.edu/s/rdmorin/GAMBL%20hg19?position=chr18%3A60796984%2D60814103)\|strong_enhancer \|
6		-\|chr18 \|60982728 \|60988342\|[TSS](https://genome.ucsc.edu/s/rdmorin/GAMBL%20hg19?position=chr18%3A60982728%2D60988342) \|active_promoter \|

...	...	@@ -0,0 +1,62 @@
	1	+---
	2	+bibliography: 'morinlab.bib'
	3	+csl: 'NLM.csl'
	4	+link-citations: true
	5	+nocite: \|
	6	+ @balSuperenhancerHypermutationAlters2022, @tanakaFrequentIncidenceSomatic1992, @sarkozyMutationalLandscapeGray2021, @burkhardtClinicalRelevanceMolecular2022
	7	+---
	8	+
	9	+
	10	+[[_TOC_]]
	11	+
	12	+## Overview
	13	+
	14	+## Relevance tier by entity
	15	+
	16	+test
	17	+
	18	+[[include:Template_Relevance.md]]
	19	+
	20	+## Warnings
	21	+
	22	+may not exist
	23	+
	24	+## Mutation incidence from meta-analysis
	25	+sub headings per file here unless there is just one
	26	+
	27	+### DLBCL
	28	+[[include:tables/DLBCL_BCL2.md]]
	29	+
	30	+### FL
	31	+[[include:tables/FL_BCL2.md]]
	32	+
	33	+### BL
	34	+[[include:tables/BL_BCL2.md]]
	35	+
	36	+## Mutation pattern and selective pressure estimates
	37	+
	38	+[[include:tables/dnds_BCL2.md]]
	39	+
	40	+## aSHM regions
	41	+
	42	+section will only exist for certain genes
	43	+
	44	+\|chr_name\|hg19_start\|hg19_end\|region\|regulatory_comment\|
	45	+\|:--------:\|:----------:\|:--------:\|:--------:\|:------------------:\|
	46	+\|chr6 \|90981034 \|91016134\|[TSS](https://genome.ucsc.edu/s/rdmorin/GAMBL%20hg19?position=chr6%3A90981034%2D91016134)\|NA\|
	47	+
	48	+## Hotspots
	49	+
	50	+section will only exist for certain genes
	51	+
	52	+[[include:Template_Browser.md]]
	53	+
	54	+## Expression
	55	+
	56	+![](images/gene_expression/ZNF296_by_pathology.svg)
	57	+
	58	+[[include:Template_History.md]]
	59	+
	60	+## References
	61	+
	62	+

...	...	@@ -0,0 +1,11 @@
	1	+## Browse mutations
	2	+
	3	+### Protein
	4	+View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/BCL2_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/BCL2_protein_hg38.html)
	5	+
	6	+![](images/proteinpaint/BCL2_NM_000633.svg)
	7	+
	8	+### Genome
	9	+View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/BCL2.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/BCL2_hg38.html)
	10	+
	11	+![](images/proteinpaint/BCL2.svg)

...	...	@@ -0,0 +1,2 @@
	1	+## Expression
	2	+![](images/gene_expression/BCL2_by_pathology.svg)

...	...	@@ -0,0 +1,11 @@
	1	+## History
	2	+
	3	+```mermaid
	4	+%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
	5	+timeline
	6	+ title Publication timing
	7	+ 1992-01-01 : Tanaka : DLBCL
	8	+ 2011-07-27 : Morin : FL
	9	+ 2021-04-01 : Sarkozy : PMBL
	10	+ 2022-07-06 : Burkhardt : BL
	11	+```
...	...	\ No newline at end of file

...	...	@@ -0,0 +1,14 @@
	1	+## Hotspots
	2	+
	3	+\| Chromosome \|Coordinate (hg19) \| ref>alt \| HGVSp \|
	4	+ \| :---:\| :---: \| :--: \| :---: \|
	5	+\| chr18 \| 60985854 \| T>C \| M16V \|
	6	+\| chr18 \| 60985854 \| T>A \| M16L \|
	7	+\| chr18 \| 60985853 \| A>T \| M16K \|
	8	+\| chr18 \| 60985852 \| C>T \| M16I \|
	9	+\| chr18 \| 60985849 \| C>G \| K17N \|
	10	+\| chr18 \| 60985842 \| G>A \| H20Y \|
	11	+\| chr18 \| 60985840 \| A>C \| H20Q \|
	12	+\| chr18 \| 60985838 \| T>G \| Y21S \|
	13	+\| chr18 \| 60985835 \| T>C \| K22R \|
	14	+\| chr18 \| 60985834 \| CT>TC \| K22R \|

...	...	@@ -0,0 +1,5 @@
	1	+## Overview
	2	+
	3	+BCL2 mutations are frequently found in DLBCL, particularly in the germinal center B-cell (GCB) subtype, and are often located in the flexible loop domain and outside the BCL2-homology domains.
	4	+These mutations are caused by the somatic hypermutation process. The presence of these mutations are strongly correlated with the presence of a translocation between BCL2 and one of the immunoglobulin loci.
	5	+Although missense mutations may not be under positive selective pressure in the context of lymphomagenesis, some of these mutations may interfere with the function of BCL2 antagonists.

...	...	@@ -0,0 +1,9 @@
	1	+
	2	+# Test
	3	+
	4	+\|Entity\|Tier\|Description \|
	5	+\|:------:\|:----:\|--------------------------------------\|
	6	+\|![DLBCL](images/icons/tables/DLBCL_tier1.png) \|[1](DLBCL_genes#tier-1-dlbcl-genes)\|high-confidence DLBCL gene \|
	7	+\|![FL](images/icons/tables/FL_tier1.png) \|1 \|high-confidence FL gene\|
	8	+\|![PMBL](images/icons/PMtables/BL_tier2.png)\|2\|relevance in PMBL/cHL/GZL not firmly established\|
	9	+\|![BL](images/icons/tables/BL_tier2.png) \|[2](BL_genes#tier-2-bl-genes) \|relevance in BL not firmly established\|

...	...	@@ -0,0 +1,6 @@
	1	+## aSHM regions
	2	+
	3	+\|chr_name\|hg19_start\|hg19_end\|region \|regulatory_comment\|
	4	+\|:--------:\|:----------:\|:--------:\|:---------------------------------------------------------------------------------------------:\|:------------------:\|
	5	+\|chr18 \|60796984 \|60814103\|[intron](https://genome.ucsc.edu/s/rdmorin/GAMBL%20hg19?position=chr18%3A60796984%2D60814103)\|strong_enhancer \|
	6	+\|chr18 \|60982728 \|60988342\|[TSS](https://genome.ucsc.edu/s/rdmorin/GAMBL%20hg19?position=chr18%3A60982728%2D60988342) \|active_promoter \|