898ded7c11580466963dea374edb8e92f97da64c
HVCN1.md
| ... | ... | @@ -25,16 +25,8 @@ timeline |
| 25 | 25 | |
| 26 | 26 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 27 | 27 | |
| 28 | -|Entity|source |frequency (%)| |
|
| 29 | -|:------:|:---------------------:|:-------------:| |
|
| 30 | -|DLBCL |GAMBL genomes |3.06 | |
|
| 31 | -|DLBCL |Schmitz cohort |1.91 | |
|
| 32 | -|DLBCL |Reddy cohort |2.30 | |
|
| 33 | -|DLBCL |Chapuy cohort |3.42 | |
|
| 34 | -|FL |GAMBL genomes |6.47 | |
|
| 35 | -|BL |GAMBL genomes+capture|0.92 | |
|
| 36 | -|BL |Thomas cohort |0.80 | |
|
| 37 | -|BL |Panea cohort |2.00 | |
|
| 28 | +[[include:DLBCL_HVCN1.md]] |
|
| 29 | +[[include:FL_HVCN1.md]] |
|
| 38 | 30 | |
| 39 | 31 | ## Mutation pattern and selective pressure estimates |
| 40 | 32 |
IKZF3.md
| ... | ... | @@ -21,20 +21,13 @@ timeline |
| 21 | 21 | |
| 22 | 22 | |Entity|Tier|Description | |
| 23 | 23 | |:------:|:----:|--------------------------------------| |
| 24 | -| |2-a | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@paneaWholeGenomeLandscape2019]| |
|
| 25 | -| |1-a | aSHM target and high-confidence DLBCL gene [@morinMutationalStructuralAnalysis2013]| |
|
| 24 | +| |2 | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@paneaWholeGenomeLandscape2019]| |
|
| 25 | +| |1 | aSHM target and high-confidence DLBCL gene [@morinMutationalStructuralAnalysis2013]| |
|
| 26 | 26 | |
| 27 | 27 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 28 | 28 | |
| 29 | -|Entity|source |frequency (%)| |
|
| 30 | -|:------:|:---------------------:|:-------------:| |
|
| 31 | -|BL |GAMBL genomes+capture|1.62 | |
|
| 32 | -|BL |Thomas cohort |0.80 | |
|
| 33 | -|BL |Panea cohort |3.00 | |
|
| 34 | -|DLBCL |GAMBL genomes |4.78 | |
|
| 35 | -|DLBCL |Schmitz cohort |4.47 | |
|
| 36 | -|DLBCL |Reddy cohort |3.90 | |
|
| 37 | -|DLBCL |Chapuy cohort |4.27 | |
|
| 29 | +[[include:DLBCL_IKZF3.md]] |
|
| 30 | +[[include:BL_IKZF3.md]] |
|
| 38 | 31 | |
| 39 | 32 | ## Mutation pattern and selective pressure estimates |
| 40 | 33 |
IL4R.md
| ... | ... | @@ -26,12 +26,7 @@ timeline |
| 26 | 26 | |
| 27 | 27 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 28 | 28 | |
| 29 | -|Entity|source |frequency (%)| |
|
| 30 | -|:------:|:--------------:|:-------------:| |
|
| 31 | -|DLBCL |GAMBL genomes |2.68 | |
|
| 32 | -|DLBCL |Schmitz cohort|2.13 | |
|
| 33 | -|DLBCL |Reddy cohort |2.50 | |
|
| 34 | -|DLBCL |Chapuy cohort |3.85 | |
|
| 29 | +[[include:DLBCL_IL4R.md]] |
|
| 35 | 30 | |
| 36 | 31 | ## Mutation pattern and selective pressure estimates |
| 37 | 32 | |
| ... | ... | @@ -69,4 +64,4 @@ View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/I |
| 69 | 64 | <!-- DLBCL: dunsCharacterizationDLBCLPMBL2021b --> |
| 70 | 65 | <!-- PMBL: viganoSomaticIL4RMutations2018b --> |
| 71 | 66 | |
| 72 | -## References |
|
| ... | ... | \ No newline at end of file |
| 0 | +## References |