900448155a9946dfbc856e11535dd9454fc4da0f
CXCR4.md
| ... | ... | @@ -12,6 +12,7 @@ CXCR4 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) |
| 12 | 12 | ## History |
| 13 | 13 | Mutations in this gene were first described in DLBCL in 2012 by Khodabakhshi et al,<sup>1</sup> in FL in 2021 by Hübschmann et al<sup>2</sup> and in BL in 2019 by Panea et al.<sup>3</sup> |
| 14 | 14 | |
| 15 | +<<Warn("The variants reported in this gene in BL failed QC")>> |
|
| 15 | 16 | |
| 16 | 17 | ```mermaid |
| 17 | 18 | %%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%% |
HIST1H3I.md
| ... | ... | @@ -5,6 +5,8 @@ link-citations: true |
| 5 | 5 | --- |
| 6 | 6 | # HIST1H3I |
| 7 | 7 | |
| 8 | +<<Warn("The variants reported in this gene in BL failed QC")>> |
|
| 9 | + |
|
| 8 | 10 | ## History |
| 9 | 11 | ```mermaid |
| 10 | 12 | %%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%% |
PTEN.md
| ... | ... | @@ -1,3 +1,8 @@ |
| 1 | +--- |
|
| 2 | +bibliography: 'morinlab.bib' |
|
| 3 | +csl: 'NLM.csl' |
|
| 4 | +link-citations: true |
|
| 5 | +--- |
|
| 1 | 6 | # PTEN |
| 2 | 7 | |
| 3 | 8 | ## History |
| ... | ... | @@ -12,7 +17,7 @@ timeline |
| 12 | 17 | |
| 13 | 18 | |Entity|Tier|Description | |
| 14 | 19 | |:------:|:----:|--------------------------| |
| 15 | -| |1 |high-confidence BL gene | |
|
| 20 | +| |1 |high-confidence BL gene [@loveGeneticLandscapeMutations2012]| |
|
| 16 | 21 | | |1 |high-confidence DLBCL gene| |
| 17 | 22 | |
| 18 | 23 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| ... | ... | @@ -51,4 +56,4 @@ View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/P |
| 51 | 56 | <!-- BL: loveGeneticLandscapeMutations2012 --> |
| 52 | 57 | |
| 53 | 58 | ## References |
| 54 | -1. Love C, Sun Z, Jima D, Li G, Zhang J, Miles R, Richards KL, Dunphy CH, Choi WWL, Srivastava G, Lugar PL, Rizzieri DA, Lagoo AS, Bernal-Mizrachi L, Mann KP, Flowers CR, Naresh KN, Evens AM, Chadburn A, Gordon LI, Czader MB, Gill JI, Hsi ED, Greenough A, Moffitt AB, McKinney M, Banerjee A, Grubor V, Levy S, Dunson DB, Dave SS. The genetic landscape of mutations in Burkitt lymphoma. Nat Genet. 2012 Dec;44(12):1321–1325. PMCID: PMC3674561 |
|
| 59 | + |