☰

Updated B2M (markdown)

rdmorin committed 2024-05-19 09:03:29 -0700 commit 9044bf1b878bcda7f68645ea38064e15325b41a6

				B2M.md
			
          @@ -1,4 +1,5 @@

          -# [B2M]

          +

          +The B2M (β2-microglobulin) gene plays a crucial role in the function of the major histocompatibility complex (MHC) class I molecules, which are essential for immune system recognition of infected or malignant cells. B2M mutations in B-cell lymphomas, particularly in DLBCL and PMBCL, lead to reduced MHC class I expression, enabling tumor cells to evade immune detection and destruction by cytotoxic T cells. 

           ## Mutation tier

...	...	@@ -1,4 +1,5 @@
1		-# [B2M]
	1	+
	2	+The B2M (β2-microglobulin) gene plays a crucial role in the function of the major histocompatibility complex (MHC) class I molecules, which are essential for immune system recognition of infected or malignant cells. B2M mutations in B-cell lymphomas, particularly in DLBCL and PMBCL, lead to reduced MHC class I expression, enabling tumor cells to evade immune detection and destruction by cytotoxic T cells.
2	3
3	4	## Mutation tier
4	5