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MYC.md
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| 1 | -# [MYC] |
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| 1 | +MYC is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) affected by aberrant somatic hypermutation in B-cell lymphomas, which complicates the interpretation of mutations at this locus. |
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| 2 | 2 | |
| 3 | 3 | ## Mutation tier |
| 4 | 4 | |
| 5 | 5 | |Entity|Tier|Description | |
| 6 | 6 | |:------:|:----:|--------------------------------------| |
| 7 | -|BL |1 |high-confidence BL gene | |
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| 8 | -|DLBCL |1 |high-confidence DLBCL gene | |
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| 9 | -|FL |2 |relevance in FL not firmly established| |
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| 7 | +|BL |1-a |high-confidence BL gene | |
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| 8 | +|DLBCL |1-a |high-confidence DLBCL gene | |
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| 9 | +|FL |2-a |relevance of missense mutations in FL not firmly established| |
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| 10 | + |
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| 10 | 11 | ## Mutation incidence |
| 11 | 12 | |
| 12 | 13 | |Entity|source |frequency (%)| |