a72b560487a825d1cf0973fff724244794dfb646
ITPKB.md
| ... | ... | @@ -32,11 +32,7 @@ timeline |
| 32 | 32 | |
| 33 | 33 | ## Mutation pattern and selective pressure estimates |
| 34 | 34 | |
| 35 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 36 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 37 | -|BL |Yes |No |0.587 | 0.000 | |
|
| 38 | -|DLBCL |Yes |Yes |4.294 |15.744 | |
|
| 39 | -|FL |Yes |No |6.541 | 0.000 | |
|
| 35 | +[[include:dnds_ITPKB.md]] |
|
| 40 | 36 | |
| 41 | 37 | ## aSHM regions |
| 42 | 38 |
JUNB.md
| ... | ... | @@ -33,13 +33,7 @@ timeline |
| 33 | 33 | |
| 34 | 34 | ## Mutation pattern and selective pressure estimates |
| 35 | 35 | |
| 36 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 37 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 38 | -|BL |No |No |1.009 |0.00 | |
|
| 39 | -|DLBCL |No |No |1.285 |8.88 | |
|
| 40 | -|FL |No |No |0.000 |0.00 | |
|
| 41 | - |
|
| 42 | - |
|
| 36 | +[[include:dnds_JUNB.md]] |
|
| 43 | 37 | |
| 44 | 38 | > [!WARNING] |
| 45 | 39 | > Mutations in this gene were reported to be inflated in the original results according to [Dreval K](https://www.biorxiv.org/content/10.1101/2023.11.21.567983v1) |
KLF2.md
| ... | ... | @@ -37,11 +37,7 @@ timeline |
| 37 | 37 | |
| 38 | 38 | ## Mutation pattern and selective pressure estimates |
| 39 | 39 | |
| 40 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 41 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 42 | -|BL |Yes |No |2.274 |0 | |
|
| 43 | -|DLBCL |Yes |No |3.067 |0 | |
|
| 44 | -|FL |Yes |No |9.318 |0 | |
|
| 40 | +[[include:dnds_KLF2.md]] |
|
| 45 | 41 | |
| 46 | 42 | ## aSHM regions |
| 47 | 43 |
KLHL14.md
| ... | ... | @@ -30,14 +30,7 @@ timeline |
| 30 | 30 | |
| 31 | 31 | ## Mutation pattern and selective pressure estimates |
| 32 | 32 | |
| 33 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 34 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 35 | -|BL |No |No | 0.000 | 0.000 | |
|
| 36 | -|DLBCL |No |No | 3.154 | 2.846 | |
|
| 37 | -|FL |No |No |12.248 |24.944 | |
|
| 38 | - |
|
| 39 | - |
|
| 40 | - |
|
| 33 | +[[include:dnds_KLHL14.md]] |
|
| 41 | 34 | |
| 42 | 35 | ## KLHL14 Hotspots |
| 43 | 36 |
KLHL6.md
| ... | ... | @@ -33,11 +33,7 @@ timeline |
| 33 | 33 | |
| 34 | 34 | ## Mutation pattern and selective pressure estimates |
| 35 | 35 | |
| 36 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 37 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 38 | -|BL |Yes |No | 4.630 | 0.000 | |
|
| 39 | -|DLBCL |Yes |No | 7.379 | 6.684 | |
|
| 40 | -|FL |Yes |Yes |20.169 |55.914 | |
|
| 36 | +[[include:dnds_KLHL6.md]] |
|
| 41 | 37 | |
| 42 | 38 | ## aSHM regions |
| 43 | 39 |
KMT2C.md
| ... | ... | @@ -37,14 +37,7 @@ timeline |
| 37 | 37 | |
| 38 | 38 | ## Mutation pattern and selective pressure estimates |
| 39 | 39 | |
| 40 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 41 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 42 | -|BL |No |No |0.628 |0.000 | |
|
| 43 | -|DLBCL |No |No |1.569 |1.911 | |
|
| 44 | -|FL |No |No |0.550 |0.000 | |
|
| 45 | - |
|
| 46 | - |
|
| 47 | - |
|
| 40 | +[[include:dnds_KMT2C.md]] |
|
| 48 | 41 | |
| 49 | 42 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/KMT2C_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/KMT2C_protein_hg38.html) |
| 50 | 43 |
KRAS.md
| ... | ... | @@ -28,14 +28,7 @@ timeline |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |No |No |27.314 |0 | |
|
| 34 | -|DLBCL |No |No | 5.336 |0 | |
|
| 35 | -|FL |No |No | 9.959 |0 | |
|
| 36 | - |
|
| 37 | - |
|
| 38 | - |
|
| 31 | +[[include:dnds_KRAS.md]] |
|
| 39 | 32 | |
| 40 | 33 | ## KRAS Hotspots |
| 41 | 34 |
LRRN3.md
| ... | ... | @@ -28,14 +28,7 @@ timeline |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |No |No |2.141 |0 | |
|
| 34 | -|DLBCL |No |No |2.591 |0 | |
|
| 35 | -|FL |No |No |0.000 |0 | |
|
| 36 | - |
|
| 37 | - |
|
| 38 | - |
|
| 31 | +[[include:dnds_LRRN3.md]] |
|
| 39 | 32 | |
| 40 | 33 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/LRRN3_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/LRRN3_protein_hg38.html) |
| 41 | 34 |
LTB.md
| ... | ... | @@ -34,11 +34,7 @@ timeline |
| 34 | 34 | |
| 35 | 35 | ## Mutation pattern and selective pressure estimates |
| 36 | 36 | |
| 37 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 38 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 39 | -|DLBCL |Yes |No |2.261 |10.402 | |
|
| 40 | -|FL |Yes |No |5.259 |35.735 | |
|
| 41 | -|BL |Yes |No |4.330 | 0.000 | |
|
| 37 | +[[include:dnds_LTB.md]] |
|
| 42 | 38 | |
| 43 | 39 | ## aSHM regions |
| 44 | 40 |