abfc1406eb5801b1010b5208f7bb76df89739567
CREBBP.md
| ... | ... | @@ -2,6 +2,8 @@ |
| 2 | 2 | bibliography: 'morinlab.bib' |
| 3 | 3 | csl: 'NLM.csl' |
| 4 | 4 | link-citations: true |
| 5 | +nocite: | |
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| 6 | + @parryWholeExomeSequencing2013, @dunsCharacterizationDLBCLPMBL2021, @pasqualucciInactivatingMutationsAcetyltransferase2011, @loveGeneticLandscapeMutations2012 |
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| 5 | 7 | --- |
| 6 | 8 | |
| 7 | 9 | [[_TOC_]] |
| ... | ... | @@ -19,13 +21,7 @@ Mutations in CREBBP and EP300 affect a common pathway and have been described as |
| 19 | 21 | |
| 20 | 22 | ## Relevance tier by entity |
| 21 | 23 | |
| 22 | -|Entity|Tier|Description | |
|
| 23 | -|:------:|:----:|--------------------------------------| |
|
| 24 | -||2|relevance in MZL not firmly established[@parryWholeExomeSequencing2013] | |
|
| 25 | -||1|high-confidence PMBL/cHL/GZL gene[@dunsCharacterizationDLBCLPMBL2021] | |
|
| 26 | -| |1 |high-confidence DLBCL gene supported by functional data[@pasqualucciInactivatingMutationsAcetyltransferase2011] | |
|
| 27 | -| |1 |high-confidence FL gene supported by functional data[@pasqualucciInactivatingMutationsAcetyltransferase2011] | |
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| 28 | -| |2 |association with BL is tenuous[@loveGeneticLandscapeMutations2012]| |
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| 24 | +[[include:table1_CREBBP.md]] |
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| 29 | 25 | |
| 30 | 26 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 31 | 27 |
table1_CCT6B.md
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| 1 | +|Entity|Tier|Description | |
|
| 2 | +|:----:|:----:|------------------------------| |
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| 3 | +|[BL]((images/icons/BL_tier3.png)) | 3 | Mutations are unlikely to be relevant to XXX| |