ad6d78fcf693a0d9f641972a3675e1603151e278
HIST1H3B.md
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| 16 | 16 | |
| 17 | 17 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 18 | 18 | |
| 19 | -|Entity|source |frequency (%)| |
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| 20 | -|:------:|:--------------:|:-------------:| |
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| 21 | -|DLBCL |GAMBL genomes |2.10 | |
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| 22 | -|DLBCL |Schmitz cohort|1.70 | |
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| 23 | -|DLBCL |Reddy cohort |2.00 | |
|
| 24 | -|DLBCL |Chapuy cohort |2.14 | |
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| 25 | -|FL |GAMBL genomes |1.62 | |
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| 19 | +### DLBCL |
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| 20 | +[[include:DLBCL_HIST1H3B.md]] |
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| 26 | 21 | |
| 27 | -## Mutation pattern and selective pressure estimates |
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| 22 | +### BL |
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| 23 | +[[include:BL_HIST1H3B.md]] |
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| 24 | + |
|
| 25 | +### FL |
|
| 26 | +[[include:FL_HIST1H3B.md]] |
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| 28 | 27 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
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| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
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| 31 | -|BL |No |No |8.244 |0.000 | |
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| 32 | -|DLBCL |No |No |2.108 |9.678 | |
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| 33 | -|FL |No |No |1.637 |0.000 | |
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| 34 | 28 | |
| 29 | +## Mutation pattern and selective pressure estimates |
|
| 30 | +[[include:dnds_HIST1H3B.md]] |
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| 35 | 31 | |
| 36 | 32 | |
| 37 | 33 |