b12f8c033bab266459126f1080c17fd77a596a25
HIST1H2BK.md
| ... | ... | @@ -22,23 +22,17 @@ This gene encodes the H2A protein, one of the core proteins comprising nucleosom |
| 22 | 22 | |
| 23 | 23 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 24 | 24 | |
| 25 | -|Entity|source |frequency (%)| |
|
| 26 | -|:------:|:---------------------:|:-------------:| |
|
| 27 | -|BL |GAMBL genomes+capture|5.31 | |
|
| 28 | -|BL |Thomas cohort |4.70 | |
|
| 29 | -|BL |Panea cohort |7.90 | |
|
| 30 | -|DLBCL |GAMBL genomes |4.59 | |
|
| 31 | -|DLBCL |Schmitz cohort |5.32 | |
|
| 32 | -|DLBCL |Reddy cohort |4.20 | |
|
| 33 | -|DLBCL |Chapuy cohort |5.56 | |
|
| 25 | +### DLBCL |
|
| 26 | +[[include:DLBCL_HIST1H2BK.md]] |
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| 34 | 27 | |
| 35 | -## Mutation pattern and selective pressure estimates |
|
| 28 | +### BL |
|
| 29 | +[[include:BL_HIST1H2BK.md]] |
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| 30 | + |
|
| 31 | +### FL |
|
| 32 | +[[include:FL_HIST1H2BK.md]] |
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| 36 | 33 | |
| 37 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 38 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 39 | -|BL |No |No |4.421 |0 | |
|
| 40 | -|DLBCL |No |No |1.567 |0 | |
|
| 41 | -|FL |No |No |0.760 |0 | |
|
| 34 | +## Mutation pattern and selective pressure estimates |
|
| 35 | +[[include:dnds_HIST1H2BK.md]] |
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| 42 | 36 | |
| 43 | 37 | |
| 44 | 38 |