b324f46a7caa6460534483ad60252cace5110eff
MYC.md
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| 1 | +--- |
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| 2 | +bibliography: 'morinlab.bib' |
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| 3 | +csl: 'NLM.csl' |
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| 4 | +link-citations: true |
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| 5 | +--- |
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| 1 | 6 | # MYC |
| 2 | 7 | |
| 3 | 8 | ## Overview |
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| 18 | 23 | |
| 19 | 24 | |Entity|Tier|Description | |
| 20 | 25 | |:------:|:----:|--------------------------------------| |
| 21 | -||2|relevance in PMBL/cHL/GZL not firmly established| |
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| 22 | -||2|relevance in MZL not firmly established| |
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| 23 | -| |1-a | aSHM target and high-confidence BL gene | |
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| 24 | -| |1-a | aSHM target and high-confidence DLBCL gene | |
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| 26 | +||2|relevance in PMBL/cHL/GZL not firmly established[@dunsCharacterizationDLBCLPMBL2021b]| |
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| 27 | +||2|relevance in MZL not firmly established[@jalladesExomeSequencingIdentifies2017]| |
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| 28 | +| |1-a | aSHM target and high-confidence BL gene [@johnstonCmycHypermutationBurkitt1992]| |
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| 29 | +| |1-a | aSHM target and high-confidence DLBCL gene [@pasqualucciHypermutationMultipleProtooncogenes2001a]| |
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| 25 | 30 | | |2-a | aSHM target; Although recurrent, the relevance of mutations in FL is tenuous | |
| 26 | 31 | |
| 27 | 32 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |