ba039f0df0ee6104fa2143acd4ddf36d100e5e73
.gitignore
| ... | ... | @@ -1 +1,2 @@ |
| 1 | 1 | *DS_Store |
| 2 | +._* |
ABL2.md
| ... | ... | @@ -14,6 +14,7 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### FL |
|
| 17 | 18 | [[include:tables/FL_ABL2.md]] |
| 18 | 19 | |
| 19 | 20 | ## Mutation pattern and selective pressure estimates |
ACTB.md
| ... | ... | @@ -21,7 +21,10 @@ ACTB is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_ACTB.md]] |
| 26 | + |
|
| 27 | +### FL |
|
| 25 | 28 | [[include:tables/FL_ACTB.md]] |
| 26 | 29 | |
| 27 | 30 | ## Mutation pattern and selective pressure estimates |
ACTG1.md
| ... | ... | @@ -23,7 +23,10 @@ The function of mutations in ACTB and ACTG1 have not yet been determined.[@witje |
| 23 | 23 | |
| 24 | 24 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 25 | |
| 26 | +### DLBCL |
|
| 26 | 27 | [[include:tables/DLBCL_ACTG1.md]] |
| 28 | + |
|
| 29 | +### FL |
|
| 27 | 30 | [[include:tables/FL_ACTG1.md]] |
| 28 | 31 | |
| 29 | 32 | ## Mutation pattern and selective pressure estimates |
ADNP.md
| ... | ... | @@ -14,6 +14,7 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### BL |
|
| 17 | 18 | [[include:tables/BL_ADNP.md]] |
| 18 | 19 | |
| 19 | 20 | ## Mutation pattern and selective pressure estimates |
AFAP1L2.md
| ... | ... | @@ -18,6 +18,7 @@ nocite: | |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_AFAP1L2.md]] |
| 22 | 23 | |
| 23 | 24 | ## Mutation pattern and selective pressure estimates |
AICDA.md
| ... | ... | @@ -14,6 +14,7 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### DLBCL |
|
| 17 | 18 | [[include:tables/DLBCL_AICDA.md]] |
| 18 | 19 | |
| 19 | 20 | ## Mutation pattern and selective pressure estimates |
ALPK2.md
| ... | ... | @@ -20,6 +20,7 @@ nocite: | |
| 20 | 20 | |
| 21 | 21 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 22 | 22 | |
| 23 | +### BL |
|
| 23 | 24 | [[include:tables/BL_ALPK2.md]] |
| 24 | 25 | |
| 25 | 26 | ## Mutation pattern and selective pressure estimates |
ATM.md
| ... | ... | @@ -23,6 +23,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 23 | 23 | |
| 24 | 24 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 25 | |
| 26 | +### DLBCL |
|
| 26 | 27 | [[include:tables/DLBCL_ATM.md]] |
| 27 | 28 | |
| 28 | 29 | ## Mutation pattern and selective pressure estimates |
ATP6AP1.md
| ... | ... | @@ -14,6 +14,7 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### FL |
|
| 17 | 18 | [[include:tables/FL_ATP6AP1.md]] |
| 18 | 19 | |
| 19 | 20 | ## Mutation pattern and selective pressure estimates |
ATP6V1B2.md
| ... | ... | @@ -18,6 +18,7 @@ Driver mutations affecting this gene in FL have been experimentally demonstrated |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### FL |
|
| 21 | 22 | [[include:tables/FL_ATP6V1B2.md]] |
| 22 | 23 | |
| 23 | 24 | ## Mutation pattern and selective pressure estimates |
B2M.md
| ... | ... | @@ -24,7 +24,10 @@ B2M mutations in B-cell lymphomas, particularly in DLBCL and PMBCL, lead to redu |
| 24 | 24 | |
| 25 | 25 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 26 | 26 | |
| 27 | +### DLBCL |
|
| 27 | 28 | [[include:tables/DLBCL_B2M.md]] |
| 29 | + |
|
| 30 | +### FL |
|
| 28 | 31 | [[include:tables/FL_B2M.md]] |
| 29 | 32 | |
| 30 | 33 | ## Mutation pattern and selective pressure estimates |
BACH2.md
| ... | ... | @@ -22,6 +22,7 @@ Driver mutations affecting this gene in BL have been experimentally demonstrated |
| 22 | 22 | |
| 23 | 23 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 24 | 24 | |
| 25 | +### BL |
|
| 25 | 26 | [[include:tables/BL_BACH2.md]] |
| 26 | 27 | |
| 27 | 28 | ## Mutation pattern and selective pressure estimates |
BCL10.md
| ... | ... | @@ -26,7 +26,10 @@ BCL10 missense mutations in the CARD domain and truncating mutations have distin |
| 26 | 26 | |
| 27 | 27 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 28 | 28 | |
| 29 | +### DLBCL |
|
| 29 | 30 | [[include:tables/DLBCL_BCL10.md]] |
| 31 | + |
|
| 32 | +### FL |
|
| 30 | 33 | [[include:tables/FL_BCL10.md]] |
| 31 | 34 | |
| 32 | 35 |
BIRC6.md
| ... | ... | @@ -19,7 +19,10 @@ BIRC6, as a negative regulator of non-canonical NF-κB signaling, is implicated |
| 19 | 19 | |
| 20 | 20 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 21 | 21 | |
| 22 | +### DLBCL |
|
| 22 | 23 | [[include:tables/DLBCL_BIRC6.md]] |
| 24 | + |
|
| 25 | +### FL |
|
| 23 | 26 | [[include:tables/FL_BIRC6.md]] |
| 24 | 27 | |
| 25 | 28 | ## Mutation pattern and selective pressure estimates |
BMP7.md
| ... | ... | @@ -14,6 +14,7 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### BL |
|
| 17 | 18 | [[include:tables/BL_BMP7.md]] |
| 18 | 19 | |
| 19 | 20 | ## Mutation pattern and selective pressure estimates |
BRAF.md
| ... | ... | @@ -30,6 +30,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 30 | 30 | |
| 31 | 31 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 32 | 32 | |
| 33 | +### DLBCL |
|
| 33 | 34 | [[include:tables/DLBCL_BRAF.md]] |
| 34 | 35 | |
| 35 | 36 | ## Mutation pattern and selective pressure estimates |
BTG2.md
| ... | ... | @@ -25,7 +25,10 @@ BTG2 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) |
| 25 | 25 | |
| 26 | 26 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 27 | 27 | |
| 28 | +### DLBCL |
|
| 28 | 29 | [[include:tables/DLBCL_BTG2.md]] |
| 30 | + |
|
| 31 | +### FL |
|
| 29 | 32 | [[include:tables/FL_BTG2.md]] |
| 30 | 33 | |
| 31 | 34 | ## Mutation pattern and selective pressure estimates |
BTK.md
| ... | ... | @@ -19,7 +19,10 @@ Driver mutations affecting this gene in FL/DLBCL have been experimentally demons |
| 19 | 19 | |
| 20 | 20 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 21 | 21 | |
| 22 | +### DLBCL |
|
| 22 | 23 | [[include:tables/DLBCL_BTK.md]] |
| 24 | + |
|
| 25 | +### FL |
|
| 23 | 26 | [[include:tables/FL_BTK.md]] |
| 24 | 27 | |
| 25 | 28 | ## Mutation pattern and selective pressure estimates |
CCND3.md
| ... | ... | @@ -21,8 +21,13 @@ Somatic mutations in CCND3 often stabilize the Cyclin D3 protein by altering the |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_CCND3.md]] |
| 26 | + |
|
| 27 | +### FL |
|
| 25 | 28 | [[include:tables/FL_CCND3.md]] |
| 29 | + |
|
| 30 | +### BL |
|
| 26 | 31 | [[include:tables/BL_CCND3.md]] |
| 27 | 32 | |
| 28 | 33 | ## Mutation pattern and selective pressure estimates |
CD58.md
| ... | ... | @@ -23,6 +23,7 @@ This is often accompanied by mutations in the β2-Microglobulin gene, which furt |
| 23 | 23 | |
| 24 | 24 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 25 | |
| 26 | +### DLBCL |
|
| 26 | 27 | [[include:tables/DLBCL_CD58.md]] |
| 27 | 28 | |
| 28 | 29 | ## Mutation pattern and selective pressure estimates |
CD70.md
| ... | ... | @@ -26,7 +26,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 26 | 26 | |
| 27 | 27 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 28 | 28 | |
| 29 | +### DLBCL |
|
| 29 | 30 | [[include:tables/DLBCL_CD70.md]] |
| 31 | + |
|
| 32 | +### FL |
|
| 30 | 33 | [[include:tables/FL_CD70.md]] |
| 31 | 34 | |
| 32 | 35 | ## Mutation pattern and selective pressure estimates |
CD74.md
| ... | ... | @@ -14,6 +14,7 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### DLBCL |
|
| 17 | 18 | [[include:tables/DLBCL_CD74.md]] |
| 18 | 19 | |
| 19 | 20 | ## Mutation pattern and selective pressure estimates |
CD83.md
| ... | ... | @@ -23,7 +23,10 @@ Mutations in this gene were first described in DLBCL in 2013 by Morin et al[@mor |
| 23 | 23 | |
| 24 | 24 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 25 | |
| 26 | +### DLBCL |
|
| 26 | 27 | [[include:tables/DLBCL_CD83.md]] |
| 28 | + |
|
| 29 | +### FL |
|
| 27 | 30 | [[include:tables/FL_CD83.md]] |
| 28 | 31 | |
| 29 | 32 | ## Mutation pattern and selective pressure estimates |
CDKN2A.md
| ... | ... | @@ -21,6 +21,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_CDKN2A.md]] |
| 25 | 26 | |
| 26 | 27 | ## Mutation pattern and selective pressure estimates |
CHD8.md
| ... | ... | @@ -18,7 +18,10 @@ nocite: | |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_CHD8.md]] |
| 23 | + |
|
| 24 | +### BL |
|
| 22 | 25 | [[include:tables/BL_CHD8.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
CIITA.md
| ... | ... | @@ -21,7 +21,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_CIITA.md]] |
| 26 | + |
|
| 27 | +### FL |
|
| 25 | 28 | [[include:tables/FL_CIITA.md]] |
| 26 | 29 | |
| 27 | 30 | ## Mutation pattern and selective pressure estimates |
CREBBP.md
| ... | ... | @@ -25,8 +25,13 @@ Mutations in CREBBP and EP300 affect a common pathway and have been described as |
| 25 | 25 | |
| 26 | 26 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 27 | 27 | |
| 28 | +### DLBCL |
|
| 28 | 29 | [[include:tables/DLBCL_CREBBP.md]] |
| 30 | + |
|
| 31 | +### FL |
|
| 29 | 32 | [[include:tables/FL_CREBBP.md]] |
| 33 | + |
|
| 34 | +### BL |
|
| 30 | 35 | [[include:tables/BL_CREBBP.md]] |
| 31 | 36 | |
| 32 | 37 | ## Mutation pattern and selective pressure estimates |
CTSS.md
| ... | ... | @@ -19,7 +19,10 @@ Driver mutations affecting this gene in FL have been experimentally demonstrated |
| 19 | 19 | |
| 20 | 20 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 21 | 21 | |
| 22 | +### DLBCL |
|
| 22 | 23 | [[include:tables/DLBCL_CTSS.md]] |
| 24 | + |
|
| 25 | +### FL |
|
| 23 | 26 | [[include:tables/FL_CTSS.md]] |
| 24 | 27 | |
| 25 | 28 | ## Mutation pattern and selective pressure estimates |
CXCR4.md
| ... | ... | @@ -25,7 +25,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 25 | 25 | |
| 26 | 26 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 27 | 27 | |
| 28 | +### DLBCL |
|
| 28 | 29 | [[include:tables/DLBCL_CXCR4.md]] |
| 30 | + |
|
| 31 | +### FL |
|
| 29 | 32 | [[include:tables/FL_CXCR4.md]] |
| 30 | 33 | |
| 31 | 34 | ## Mutation pattern and selective pressure estimates |
DDX3X.md
| ... | ... | @@ -22,8 +22,13 @@ Driver mutations affecting this gene in DLBCL/BL have been experimentally demons |
| 22 | 22 | |
| 23 | 23 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 24 | 24 | |
| 25 | +### DLBCL |
|
| 25 | 26 | [[include:tables/DLBCL_DDX3X.md]] |
| 27 | + |
|
| 28 | +### FL |
|
| 26 | 29 | [[include:tables/FL_DDX3X.md]] |
| 30 | + |
|
| 31 | +### BL |
|
| 27 | 32 | [[include:tables/BL_DDX3X.md]] |
| 28 | 33 | |
| 29 | 34 | ## Mutation pattern and selective pressure estimates |
DTX1.md
| ... | ... | @@ -18,7 +18,10 @@ Mutations in the DTX1 gene, which encodes the E3 ubiquitin ligase Deltex 1, have |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_DTX1.md]] |
| 23 | + |
|
| 24 | +### FL |
|
| 22 | 25 | [[include:tables/FL_DTX1.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
DUSP2.md
| ... | ... | @@ -23,7 +23,10 @@ The mutation pattern in DLBCL implies the preferential accumulation of *inactiva |
| 23 | 23 | |
| 24 | 24 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 25 | |
| 26 | +### DLBCL |
|
| 26 | 27 | [[include:tables/DLBCL_DUSP2.md]] |
| 28 | + |
|
| 29 | +### FL |
|
| 27 | 30 | [[include:tables/FL_DUSP2.md]] |
| 28 | 31 | |
| 29 | 32 | ## Mutation pattern and selective pressure estimates |
EBF1.md
| ... | ... | @@ -23,7 +23,10 @@ Driver mutations affecting this gene in DLBCL/FL have been experimentally demons |
| 23 | 23 | |
| 24 | 24 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 25 | |
| 26 | +### DLBCL |
|
| 26 | 27 | [[include:tables/DLBCL_EBF1.md]] |
| 28 | + |
|
| 29 | +### FL |
|
| 27 | 30 | [[include:tables/FL_EBF1.md]] |
| 28 | 31 | |
| 29 | 32 | ## Mutation pattern and selective pressure estimates |
EEF1A1.md
| ... | ... | @@ -18,7 +18,10 @@ This gene has some recurrent sites of mutations (hot spots). The mutation patter |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_EEF1A1.md]] |
| 23 | + |
|
| 24 | +### FL |
|
| 22 | 25 | [[include:tables/FL_EEF1A1.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
EP300.md
| ... | ... | @@ -22,7 +22,10 @@ Studies using genome-wide CRISPR-Cas9 screens have identified synthetic lethal i |
| 22 | 22 | |
| 23 | 23 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 24 | 24 | |
| 25 | +### DLBCL |
|
| 25 | 26 | [[include:tables/DLBCL_EP300.md]] |
| 27 | + |
|
| 28 | +### FL |
|
| 26 | 29 | [[include:tables/FL_EP300.md]] |
| 27 | 30 | |
| 28 | 31 | ## Mutation pattern and selective pressure estimates |
EPHB2.md
| ... | ... | @@ -23,6 +23,7 @@ nocite: | |
| 23 | 23 | |
| 24 | 24 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 25 | |
| 26 | +### BL |
|
| 26 | 27 | [[include:tables/BL_EPHB2.md]] |
| 27 | 28 | |
| 28 | 29 | ## Mutation pattern and selective pressure estimates |
ETS1.md
| ... | ... | @@ -26,7 +26,10 @@ The mutation pattern in DLBCL implies the preferential accumulation of *inactiva |
| 26 | 26 | |
| 27 | 27 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 28 | 28 | |
| 29 | +### DLBCL |
|
| 29 | 30 | [[include:tables/DLBCL_ETS1.md]] |
| 31 | + |
|
| 32 | +### FL |
|
| 30 | 33 | [[include:tables/FL_ETS1.md]] |
| 31 | 34 | |
| 32 | 35 | ## Mutation pattern and selective pressure estimates |
ETV6.md
| ... | ... | @@ -26,6 +26,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 26 | 26 | |
| 27 | 27 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 28 | 28 | |
| 29 | +### DLBCL |
|
| 29 | 30 | [[include:tables/DLBCL_ETV6.md]] |
| 30 | 31 | |
| 31 | 32 | ## Mutation pattern and selective pressure estimates |
EZH2.md
| ... | ... | @@ -28,7 +28,10 @@ Combination therapies including EZH2 inhibitors are also under exploration for D |
| 28 | 28 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 29 | 29 | |
| 30 | 30 | |
| 31 | +### DLBCL |
|
| 31 | 32 | [[include:tables/DLBCL_EZH2.md]] |
| 33 | + |
|
| 34 | +### FL |
|
| 32 | 35 | [[include:tables/FL_EZH2.md]] |
| 33 | 36 | |
| 34 | 37 | ## Mutation pattern and selective pressure estimates |
FAS.md
| ... | ... | @@ -25,7 +25,10 @@ Driver mutations affecting this gene in FL/DLBCL have been experimentally demons |
| 25 | 25 | |
| 26 | 26 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 27 | 27 | |
| 28 | +### DLBCL |
|
| 28 | 29 | [[include:tables/DLBCL_FAS.md]] |
| 30 | + |
|
| 31 | +### FL |
|
| 29 | 32 | [[include:tables/FL_FAS.md]] |
| 30 | 33 | |
| 31 | 34 | ## Mutation pattern and selective pressure estimates |
FBXO11.md
| ... | ... | @@ -23,7 +23,10 @@ Driver mutations affecting this gene in DLBCL/BL have been experimentally demons |
| 23 | 23 | |
| 24 | 24 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 25 | |
| 26 | +### DLBCL |
|
| 26 | 27 | [[include:tables/DLBCL_FBXO11.md]] |
| 28 | + |
|
| 29 | +### BL |
|
| 27 | 30 | [[include:tables/BL_FBXO11.md]] |
| 28 | 31 | |
| 29 | 32 | ## Mutation pattern and selective pressure estimates |
FBXW7.md
| ... | ... | @@ -24,6 +24,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 24 | 24 | |
| 25 | 25 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 26 | 26 | |
| 27 | +### DLBCL |
|
| 27 | 28 | [[include:tables/DLBCL_FBXW7.md]] |
| 28 | 29 | |
| 29 | 30 | ## Mutation pattern and selective pressure estimates |
FOXO1.md
| ... | ... | @@ -21,8 +21,13 @@ Driver mutations affecting this gene in FL/DLBCL/BL have been experimentally dem |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_FOXO1.md]] |
| 26 | + |
|
| 27 | +### FL |
|
| 25 | 28 | [[include:tables/FL_FOXO1.md]] |
| 29 | + |
|
| 30 | +### BL |
|
| 26 | 31 | [[include:tables/BL_FOXO1.md]] |
| 27 | 32 | |
| 28 | 33 | ## Mutation pattern and selective pressure estimates |
GNA13.md
| ... | ... | @@ -22,8 +22,13 @@ Driver mutations affecting this gene in BL/FL/DLBCL have been experimentally dem |
| 22 | 22 | |
| 23 | 23 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 24 | 24 | |
| 25 | +### DLBCL |
|
| 25 | 26 | [[include:tables/DLBCL_GNA13.md]] |
| 27 | + |
|
| 28 | +### FL |
|
| 26 | 29 | [[include:tables/FL_GNA13.md]] |
| 30 | + |
|
| 31 | +### BL |
|
| 27 | 32 | [[include:tables/BL_GNA13.md]] |
| 28 | 33 | |
| 29 | 34 | ## Mutation pattern and selective pressure estimates |
GNAI2.md
| ... | ... | @@ -23,8 +23,13 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 23 | 23 | |
| 24 | 24 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 25 | |
| 26 | +### DLBCL |
|
| 26 | 27 | [[include:tables/DLBCL_GNAI2.md]] |
| 28 | + |
|
| 29 | +### FL |
|
| 27 | 30 | [[include:tables/FL_GNAI2.md]] |
| 31 | + |
|
| 32 | +### BL |
|
| 28 | 33 | [[include:tables/BL_GNAI2.md]] |
| 29 | 34 | |
| 30 | 35 | ## Mutation pattern and selective pressure estimates |
GRB2.md
| ... | ... | @@ -20,6 +20,7 @@ Further research is needed to elucidate its specific role in DLBCL. |
| 20 | 20 | |
| 21 | 21 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 22 | 22 | |
| 23 | +### DLBCL |
|
| 23 | 24 | [[include:tables/DLBCL_GRB2.md]] |
| 24 | 25 | |
| 25 | 26 | ## Mutation pattern and selective pressure estimates |
GRHPR.md
| ... | ... | @@ -17,6 +17,7 @@ GRHPR is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) |
| 17 | 17 | |
| 18 | 18 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 19 | 19 | |
| 20 | +### DLBCL |
|
| 20 | 21 | [[include:tables/DLBCL_GRHPR.md]] |
| 21 | 22 | |
| 22 | 23 | ## Mutation pattern and selective pressure estimates |
HIST1H1E.md
| ... | ... | @@ -21,8 +21,13 @@ Mutations in this gene were first described in DLBCL in 2013 by Morin et al.[@mo |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_HIST1H1E.md]] |
| 26 | + |
|
| 27 | +### FL |
|
| 25 | 28 | [[include:tables/FL_HIST1H1E.md]] |
| 29 | + |
|
| 30 | +### BL |
|
| 26 | 31 | [[include:tables/BL_HIST1H1E.md]] |
| 27 | 32 | |
| 28 | 33 | ## Mutation pattern and selective pressure estimates |
HLA-A.md
| ... | ... | @@ -22,6 +22,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 22 | 22 | |
| 23 | 23 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 24 | 24 | |
| 25 | +### DLBCL |
|
| 25 | 26 | [[include:tables/DLBCL_HLA-A.md]] |
| 26 | 27 | |
| 27 | 28 | ## Mutation pattern and selective pressure estimates |
HLA-B.md
| ... | ... | @@ -22,7 +22,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 22 | 22 | |
| 23 | 23 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 24 | 24 | |
| 25 | +### DLBCL |
|
| 25 | 26 | [[include:tables/DLBCL_HLA-B.md]] |
| 27 | + |
|
| 28 | +### FL |
|
| 26 | 29 | [[include:tables/FL_HLA-B.md]] |
| 27 | 30 | |
| 28 | 31 | ## Mutation pattern and selective pressure estimates |
HLA-C.md
| ... | ... | @@ -23,6 +23,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 23 | 23 | |
| 24 | 24 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 25 | |
| 26 | +### DLBCL |
|
| 26 | 27 | [[include:tables/DLBCL_HLA-C.md]] |
| 27 | 28 | |
| 28 | 29 | ## Mutation pattern and selective pressure estimates |
HLA-DMB.md
| ... | ... | @@ -19,6 +19,7 @@ Mutations in this gene were first described in DLBCL by [Hübschmann et al](pape |
| 19 | 19 | |
| 20 | 20 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 21 | 21 | |
| 22 | +### DLBCL |
|
| 22 | 23 | [[include:tables/DLBCL_HLA-DMB.md]] |
| 23 | 24 | |
| 24 | 25 | ## Mutation pattern and selective pressure estimates |
HVCN1.md
| ... | ... | @@ -17,7 +17,10 @@ HVCN1, a voltage-gated proton channel, has been identified as recurrently mutate |
| 17 | 17 | |
| 18 | 18 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 19 | 19 | |
| 20 | +### DLBCL |
|
| 20 | 21 | [[include:tables/DLBCL_HVCN1.md]] |
| 22 | + |
|
| 23 | +### FL |
|
| 21 | 24 | [[include:tables/FL_HVCN1.md]] |
| 22 | 25 | |
| 23 | 26 | ## Mutation pattern and selective pressure estimates |
Home.md
| ... | ... | @@ -43,7 +43,7 @@ To get started, select one of the gene lists from the table below then select th |
| 43 | 43 | |
| 44 | 44 | ## History |
| 45 | 45 | |
| 46 | -### DLBCL, FL and BL |
|
| 46 | +### DLBCL, FL and BL studies |
|
| 47 | 47 | |
| 48 | 48 | ```mermaid |
| 49 | 49 | --- |
| ... | ... | @@ -168,7 +168,7 @@ BL RNA-seq, Schmitz 2012, 19 |
| 168 | 168 | ``` |
| 169 | 169 | |
| 170 | 170 | |
| 171 | -### History of lymphoma genes in rare entities |
|
| 171 | +### MCL, MZL and PMBL |
|
| 172 | 172 | |
| 173 | 173 | ```mermaid |
| 174 | 174 | --- |
| ... | ... | @@ -294,7 +294,7 @@ PMBL panel, Desch 2020, 10 |
| 294 | 294 | |
| 295 | 295 | **Tier 3** - Tier 3 is reserved for genes that were once nominated as a driver but have since been retired due to a lack of support in the original study nominating them. |
| 296 | 296 | |
| 297 | -For more details, visit (this page)(Supplemental_Methods_and_Results) |
|
| 297 | +For more details, visit [this page](Supplemental_Methods_and_Results) |
|
| 298 | 298 | |
| 299 | 299 | ## Other resources available for each gene |
| 300 | 300 |
ID3.md
| ... | ... | @@ -19,7 +19,10 @@ The existence of mutations in DLBCL were described in 2012 by Schmitz et al[@sch |
| 19 | 19 | |
| 20 | 20 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 21 | 21 | |
| 22 | +### DLBCL |
|
| 22 | 23 | [[include:tables/DLBCL_ID3.md]] |
| 24 | + |
|
| 25 | +### BL |
|
| 23 | 26 | [[include:tables/BL_ID3.md]] |
| 24 | 27 | |
| 25 | 28 | ## Mutation pattern and selective pressure estimates |
IKZF3.md
| ... | ... | @@ -21,7 +21,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_IKZF3.md]] |
| 26 | + |
|
| 27 | +### BL |
|
| 25 | 28 | [[include:tables/BL_IKZF3.md]] |
| 26 | 29 | |
| 27 | 30 | ## Mutation pattern and selective pressure estimates |
IL4R.md
| ... | ... | @@ -21,6 +21,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_IL4R.md]] |
| 25 | 26 | |
| 26 | 27 | ## Mutation pattern and selective pressure estimates |
IRF4.md
| ... | ... | @@ -20,7 +20,10 @@ There are a few mutation hotspots in this gene. The functional role of mutations |
| 20 | 20 | |
| 21 | 21 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 22 | 22 | |
| 23 | +### DLBCL |
|
| 23 | 24 | [[include:tables/DLBCL_IRF4.md]] |
| 25 | + |
|
| 26 | +### FL |
|
| 24 | 27 | [[include:tables/FL_IRF4.md]] |
| 25 | 28 | |
| 26 | 29 | ## Mutation pattern and selective pressure estimates |
IRF8.md
| ... | ... | @@ -25,8 +25,13 @@ Driver mutations affecting this gene in DLBCL/FL have been experimentally demons |
| 25 | 25 | |
| 26 | 26 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 27 | 27 | |
| 28 | +### DLBCL |
|
| 28 | 29 | [[include:tables/DLBCL_IRF8.md]] |
| 30 | + |
|
| 31 | +### FL |
|
| 29 | 32 | [[include:tables/FL_IRF8.md]] |
| 33 | + |
|
| 34 | +### BL |
|
| 30 | 35 | [[include:tables/BL_IRF8.md]] |
| 31 | 36 | |
| 32 | 37 | ## Mutation pattern and selective pressure estimates |
ITPKB.md
| ... | ... | @@ -21,7 +21,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_ITPKB.md]] |
| 26 | + |
|
| 27 | +### FL |
|
| 25 | 28 | [[include:tables/FL_ITPKB.md]] |
| 26 | 29 | |
| 27 | 30 | ## Mutation pattern and selective pressure estimates |
JUNB.md
| ... | ... | @@ -25,6 +25,7 @@ Mutations in this gene were reported to be inflated in the original results acco |
| 25 | 25 | |
| 26 | 26 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 27 | 27 | |
| 28 | +### DLBCL |
|
| 28 | 29 | [[include:tables/DLBCL_JUNB.md]] |
| 29 | 30 | |
| 30 | 31 |
KLF2.md
| ... | ... | @@ -20,7 +20,10 @@ Contradictory to this, the mutation pattern in DLBCL implies selective pressure |
| 20 | 20 | |
| 21 | 21 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 22 | 22 | |
| 23 | +### DLBCL |
|
| 23 | 24 | [[include:tables/DLBCL_KLF2.md]] |
| 25 | + |
|
| 26 | +### FL |
|
| 24 | 27 | [[include:tables/FL_KLF2.md]] |
| 25 | 28 | |
| 26 | 29 | ## Mutation pattern and selective pressure estimates |
KLHL14.md
| ... | ... | @@ -21,6 +21,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_KLHL14.md]] |
| 25 | 26 | |
| 26 | 27 | ## Mutation pattern and selective pressure estimates |
KLHL6.md
| ... | ... | @@ -22,7 +22,10 @@ Driver mutations affecting this gene in DLBCL/FL have been experimentally demons |
| 22 | 22 | |
| 23 | 23 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 24 | 24 | |
| 25 | +### DLBCL |
|
| 25 | 26 | [[include:tables/DLBCL_KLHL6.md]] |
| 27 | + |
|
| 28 | +### FL |
|
| 26 | 29 | [[include:tables/FL_KLHL6.md]] |
| 27 | 30 | |
| 28 | 31 | ## Mutation pattern and selective pressure estimates |
KMT2C.md
| ... | ... | @@ -18,7 +18,10 @@ This gene has been reported to be recurrently mutated in DLBCL. The rate of muta |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_KMT2C.md]] |
| 23 | + |
|
| 24 | +### BL |
|
| 22 | 25 | [[include:tables/BL_KMT2C.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
KMT2D.md
| ... | ... | @@ -27,8 +27,13 @@ Driver mutations affecting this gene in BL/DLBCL/FL have been experimentally dem |
| 27 | 27 | |
| 28 | 28 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 29 | 29 | |
| 30 | +### DLBCL |
|
| 30 | 31 | [[include:tables/DLBCL_KMT2D.md]] |
| 32 | + |
|
| 33 | +### FL |
|
| 31 | 34 | [[include:tables/FL_KMT2D.md]] |
| 35 | + |
|
| 36 | +### BL |
|
| 32 | 37 | [[include:tables/BL_KMT2D.md]] |
| 33 | 38 | |
| 34 | 39 | ## Mutation pattern and selective pressure estimates |
KRAS.md
| ... | ... | @@ -21,6 +21,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_KRAS.md]] |
| 25 | 26 | |
| 26 | 27 | ## Mutation pattern and selective pressure estimates |
LRRN3.md
| ... | ... | @@ -14,6 +14,7 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### DLBCL |
|
| 17 | 18 | [[include:tables/DLBCL_LRRN3.md]] |
| 18 | 19 | |
| 19 | 20 | ## Mutation pattern and selective pressure estimates |
LTB.md
| ... | ... | @@ -17,8 +17,13 @@ LTB (Lymphotoxin Beta) is a member of the tumor necrosis factor (TNF) superfamil |
| 17 | 17 | |
| 18 | 18 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 19 | 19 | |
| 20 | +### DLBCL |
|
| 20 | 21 | [[include:tables/DLBCL_LTB.md]] |
| 22 | + |
|
| 23 | +### FL |
|
| 21 | 24 | [[include:tables/FL_LTB.md]] |
| 25 | + |
|
| 26 | +### BL |
|
| 22 | 27 | [[include:tables/BL_LTB.md]] |
| 23 | 28 | |
| 24 | 29 | ## Mutation pattern and selective pressure estimates |
MAP2K1.md
| ... | ... | @@ -18,7 +18,10 @@ Driver mutations affecting this gene in FL have been experimentally demonstrated |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_MAP2K1.md]] |
| 23 | + |
|
| 24 | +### FL |
|
| 22 | 25 | [[include:tables/FL_MAP2K1.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
MEF2B.md
| ... | ... | @@ -21,7 +21,10 @@ Thus far, there is limited information about the consequence of MEF2B mutations |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_MEF2B.md]] |
| 26 | + |
|
| 27 | +### FL |
|
| 25 | 28 | [[include:tables/FL_MEF2B.md]] |
| 26 | 29 | |
| 27 | 30 | ## Mutation pattern and selective pressure estimates |
MEF2C.md
| ... | ... | @@ -19,7 +19,10 @@ Mutations in this gene were first described in DLBCL by [Arthur et al](papers/ar |
| 19 | 19 | |
| 20 | 20 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 21 | 21 | |
| 22 | +### DLBCL |
|
| 22 | 23 | [[include:tables/DLBCL_MEF2C.md]] |
| 24 | + |
|
| 25 | +### DLBCL |
|
| 23 | 26 | [[include:tables/DLBCL_MEF2C.md]] |
| 24 | 27 | |
| 25 | 28 |
MGA.md
| ... | ... | @@ -21,6 +21,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_MGA.md]] |
| 25 | 26 | |
| 26 | 27 | ## Mutation pattern and selective pressure estimates |
MPEG1.md
| ... | ... | @@ -17,6 +17,7 @@ Mutations in MPEG1 have been described in DLBCL[@morinMutationalStructuralAnalys |
| 17 | 17 | |
| 18 | 18 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 19 | 19 | |
| 20 | +### DLBCL |
|
| 20 | 21 | [[include:tables/DLBCL_MPEG1.md]] |
| 21 | 22 | |
| 22 | 23 | ## Mutation pattern and selective pressure estimates |
MS4A1.md
| ... | ... | @@ -24,6 +24,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 24 | 24 | |
| 25 | 25 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 26 | 26 | |
| 27 | +### DLBCL |
|
| 27 | 28 | [[include:tables/DLBCL_MS4A1.md]] |
| 28 | 29 | |
| 29 | 30 | ## Mutation pattern and selective pressure estimates |
MTOR.md
| ... | ... | @@ -28,7 +28,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 28 | 28 | |
| 29 | 29 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 30 | 30 | |
| 31 | +### DLBCL |
|
| 31 | 32 | [[include:tables/DLBCL_MTOR.md]] |
| 33 | + |
|
| 34 | +### BL |
|
| 32 | 35 | [[include:tables/BL_MTOR.md]] |
| 33 | 36 | |
| 34 | 37 | ## Mutation pattern and selective pressure estimates |
MYC.md
| ... | ... | @@ -21,8 +21,13 @@ Driver mutations affecting this gene in DLBCL/FL/BL have been experimentally dem |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_MYC.md]] |
| 26 | + |
|
| 27 | +### FL |
|
| 25 | 28 | [[include:tables/FL_MYC.md]] |
| 29 | + |
|
| 30 | +### BL |
|
| 26 | 31 | [[include:tables/BL_MYC.md]] |
| 27 | 32 | |
| 28 | 33 | ## Mutation pattern and selective pressure estimates |
MYD88.md
| ... | ... | @@ -18,7 +18,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_MYD88.md]] |
| 23 | + |
|
| 24 | +### FL |
|
| 22 | 25 | [[include:tables/FL_MYD88.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
NFKBIA.md
| ... | ... | @@ -21,7 +21,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_NFKBIA.md]] |
| 26 | + |
|
| 27 | +### FL |
|
| 25 | 28 | [[include:tables/FL_NFKBIA.md]] |
| 26 | 29 | |
| 27 | 30 | ## Mutation pattern and selective pressure estimates |
NFKBIE.md
| ... | ... | @@ -23,6 +23,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 23 | 23 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 24 | 24 | |
| 25 | 25 | |
| 26 | +### DLBCL |
|
| 26 | 27 | [[include:tables/DLBCL_NFKBIE.md]] |
| 27 | 28 | |
| 28 | 29 | ## Mutation pattern and selective pressure estimates |
NFKBIZ.md
| ... | ... | @@ -21,6 +21,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_NFKBIZ.md]] |
| 25 | 26 | |
| 26 | 27 | ## Mutation pattern and selective pressure estimates |
NOL9.md
| ... | ... | @@ -14,6 +14,7 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### DLBCL |
|
| 17 | 18 | [[include:tables/DLBCL_NOL9.md]] |
| 18 | 19 | |
| 19 | 20 | ## Mutation pattern and selective pressure estimates |
NOTCH1.md
| ... | ... | @@ -27,7 +27,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 27 | 27 | |
| 28 | 28 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 29 | 29 | |
| 30 | +### DLBCL |
|
| 30 | 31 | [[include:tables/DLBCL_NOTCH1.md]] |
| 32 | + |
|
| 33 | +### BL |
|
| 31 | 34 | [[include:tables/BL_NOTCH1.md]] |
| 32 | 35 | |
| 33 | 36 | ## Mutation pattern and selective pressure estimates |
NOTCH2.md
| ... | ... | @@ -20,6 +20,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 20 | 20 | |
| 21 | 21 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 22 | 22 | |
| 23 | +### DLBCL |
|
| 23 | 24 | [[include:tables/DLBCL_NOTCH2.md]] |
| 24 | 25 | |
| 25 | 26 | ## Mutation pattern and selective pressure estimates |
OSBPL10.md
| ... | ... | @@ -17,6 +17,7 @@ OSBPL10 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ash |
| 17 | 17 | |
| 18 | 18 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 19 | 19 | |
| 20 | +### DLBCL |
|
| 20 | 21 | [[include:tables/DLBCL_OSBPL10.md]] |
| 21 | 22 | |
| 22 | 23 | ## Mutation pattern and selective pressure estimates |
P2RY8.md
| ... | ... | @@ -23,7 +23,10 @@ Driver mutations affecting this gene in BL/DLBCL have been experimentally demons |
| 23 | 23 | |
| 24 | 24 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 25 | |
| 26 | +### DLBCL |
|
| 26 | 27 | [[include:tables/DLBCL_P2RY8.md]] |
| 28 | + |
|
| 29 | +### BL |
|
| 27 | 30 | [[include:tables/BL_P2RY8.md]] |
| 28 | 31 | |
| 29 | 32 | ## Mutation pattern and selective pressure estimates |
PCBP1.md
| ... | ... | @@ -15,7 +15,10 @@ nocite: | |
| 15 | 15 | |
| 16 | 16 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 17 | 17 | |
| 18 | +### DLBCL |
|
| 18 | 19 | [[include:tables/DLBCL_PCBP1.md]] |
| 20 | + |
|
| 21 | +### BL |
|
| 19 | 22 | [[include:tables/BL_PCBP1.md]] |
| 20 | 23 | |
| 21 | 24 | ## Mutation pattern and selective pressure estimates |
PHF6.md
| ... | ... | @@ -15,7 +15,10 @@ nocite: | |
| 15 | 15 | |
| 16 | 16 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 17 | 17 | |
| 18 | +### DLBCL |
|
| 18 | 19 | [[include:tables/DLBCL_PHF6.md]] |
| 20 | + |
|
| 21 | +### BL |
|
| 19 | 22 | [[include:tables/BL_PHF6.md]] |
| 20 | 23 | |
| 21 | 24 | ## Mutation pattern and selective pressure estimates |
PIM1.md
| ... | ... | @@ -25,8 +25,13 @@ Driver mutations affecting this gene in FL/DLBCL have been experimentally demons |
| 25 | 25 | |
| 26 | 26 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 27 | 27 | |
| 28 | +### DLBCL |
|
| 28 | 29 | [[include:tables/DLBCL_PIM1.md]] |
| 30 | + |
|
| 31 | +### FL |
|
| 29 | 32 | [[include:tables/FL_PIM1.md]] |
| 33 | + |
|
| 34 | +### BL |
|
| 30 | 35 | [[include:tables/BL_PIM1.md]] |
| 31 | 36 | |
| 32 | 37 | ## Mutation pattern and selective pressure estimates |
PIM2.md
| ... | ... | @@ -18,6 +18,7 @@ PIM2 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_PIM2.md]] |
| 22 | 23 | |
| 23 | 24 | ## Mutation pattern and selective pressure estimates |
POU2AF1.md
| ... | ... | @@ -22,7 +22,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 22 | 22 | |
| 23 | 23 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 24 | 24 | |
| 25 | +### DLBCL |
|
| 25 | 26 | [[include:tables/DLBCL_POU2AF1.md]] |
| 27 | + |
|
| 28 | +### FL |
|
| 26 | 29 | [[include:tables/FL_POU2AF1.md]] |
| 27 | 30 | |
| 28 | 31 | ## Mutation pattern and selective pressure estimates |
POU2F2.md
| ... | ... | @@ -18,7 +18,10 @@ Driver mutations affecting this gene in FL/DLBCL have been experimentally demons |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_POU2F2.md]] |
| 23 | + |
|
| 24 | +### FL |
|
| 22 | 25 | [[include:tables/FL_POU2F2.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
PRDM1.md
| ... | ... | @@ -18,7 +18,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_PRDM1.md]] |
| 23 | + |
|
| 24 | +### BL |
|
| 22 | 25 | [[include:tables/BL_PRDM1.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
PTEN.md
| ... | ... | @@ -18,7 +18,10 @@ Driver mutations affecting this gene in BL/DLBCL have been experimentally demons |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_PTEN.md]] |
| 23 | + |
|
| 24 | +### BL |
|
| 22 | 25 | [[include:tables/BL_PTEN.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
PTPN6.md
| ... | ... | @@ -18,6 +18,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_PTPN6.md]] |
| 22 | 23 | |
| 23 | 24 | ## Mutation pattern and selective pressure estimates |
RB1.md
| ... | ... | @@ -19,6 +19,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 19 | 19 | |
| 20 | 20 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 21 | 21 | |
| 22 | +### DLBCL |
|
| 22 | 23 | [[include:tables/DLBCL_RB1.md]] |
| 23 | 24 | |
| 24 | 25 | ## Mutation pattern and selective pressure estimates |
RFX7.md
| ... | ... | @@ -22,7 +22,10 @@ Driver mutations affecting this gene in DLBCL/BL have been experimentally demons |
| 22 | 22 | |
| 23 | 23 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 24 | 24 | |
| 25 | +### DLBCL |
|
| 25 | 26 | [[include:tables/DLBCL_RFX7.md]] |
| 27 | + |
|
| 28 | +### BL |
|
| 26 | 29 | [[include:tables/BL_RFX7.md]] |
| 27 | 30 | |
| 28 | 31 | ## Mutation pattern and selective pressure estimates |
RHOA.md
| ... | ... | @@ -18,7 +18,10 @@ Driver mutations affecting this gene in DLBCL/BL have been experimentally demons |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_RHOA.md]] |
| 23 | + |
|
| 24 | +### BL |
|
| 22 | 25 | [[include:tables/BL_RHOA.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
RRAGC.md
| ... | ... | @@ -18,7 +18,10 @@ Driver mutations affecting this gene in DLBCL/FL have been experimentally demons |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_RRAGC.md]] |
| 23 | + |
|
| 24 | +### FL |
|
| 22 | 25 | [[include:tables/FL_RRAGC.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
S1PR2.md
| ... | ... | @@ -21,8 +21,13 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 21 | 21 | |
| 22 | 22 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 23 | 23 | |
| 24 | +### DLBCL |
|
| 24 | 25 | [[include:tables/DLBCL_S1PR2.md]] |
| 26 | + |
|
| 27 | +### FL |
|
| 25 | 28 | [[include:tables/FL_S1PR2.md]] |
| 29 | + |
|
| 30 | +### BL |
|
| 26 | 31 | [[include:tables/BL_S1PR2.md]] |
| 27 | 32 | |
| 28 | 33 | ## Mutation pattern and selective pressure estimates |
SETD1B.md
| ... | ... | @@ -10,7 +10,7 @@ nocite: | |
| 10 | 10 | |
| 11 | 11 | ## Experimental Evidence |
| 12 | 12 | |
| 13 | -Driver mutations affecting this gene in DLBCL have been experimentally demonstrated to cause a reduction or loss of function (LOF).[@] |
|
| 13 | +Driver mutations affecting this gene in DLBCL have been experimentally demonstrated to cause a reduction or loss of function (LOF). |
|
| 14 | 14 | |
| 15 | 15 | ## Relevance tier by entity |
| 16 | 16 | |
| ... | ... | @@ -18,6 +18,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_SETD1B.md]] |
| 22 | 23 | |
| 23 | 24 | ## Mutation pattern and selective pressure estimates |
SF3B1.md
| ... | ... | @@ -23,7 +23,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 23 | 23 | |
| 24 | 24 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 25 | |
| 26 | +### DLBCL |
|
| 26 | 27 | [[include:tables/DLBCL_SF3B1.md]] |
| 28 | + |
|
| 29 | +### BL |
|
| 27 | 30 | [[include:tables/BL_SF3B1.md]] |
| 28 | 31 | |
| 29 | 32 | ## Mutation pattern and selective pressure estimates |
SGK1.md
| ... | ... | @@ -18,7 +18,10 @@ Driver mutations affecting this gene in FL/DLBCL have been experimentally demons |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_SGK1.md]] |
| 23 | + |
|
| 24 | +### FL |
|
| 22 | 25 | [[include:tables/FL_SGK1.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
SIN3A.md
| ... | ... | @@ -15,7 +15,10 @@ nocite: | |
| 15 | 15 | |
| 16 | 16 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 17 | 17 | |
| 18 | +### DLBCL |
|
| 18 | 19 | [[include:tables/DLBCL_SIN3A.md]] |
| 20 | + |
|
| 21 | +### BL |
|
| 19 | 22 | [[include:tables/BL_SIN3A.md]] |
| 20 | 23 | |
| 21 | 24 | ## Mutation pattern and selective pressure estimates |
SMARCA4.md
| ... | ... | @@ -24,8 +24,13 @@ Driver mutations affecting this gene in DLBCL/FL/BL have been experimentally dem |
| 24 | 24 | |
| 25 | 25 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 26 | 26 | |
| 27 | +### DLBCL |
|
| 27 | 28 | [[include:tables/DLBCL_SMARCA4.md]] |
| 29 | + |
|
| 30 | +### FL |
|
| 28 | 31 | [[include:tables/FL_SMARCA4.md]] |
| 32 | + |
|
| 33 | +### BL |
|
| 29 | 34 | [[include:tables/BL_SMARCA4.md]] |
| 30 | 35 | |
| 31 | 36 | ## Mutation pattern and selective pressure estimates |
SOCS1.md
| ... | ... | @@ -18,7 +18,10 @@ Driver mutations affecting this gene in FL/DLBCL have been experimentally demons |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_SOCS1.md]] |
| 23 | + |
|
| 24 | +### FL |
|
| 22 | 25 | [[include:tables/FL_SOCS1.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
SPEN.md
| ... | ... | @@ -15,6 +15,7 @@ nocite: | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | 17 | |
| 18 | +### DLBCL |
|
| 18 | 19 | [[include:tables/DLBCL_SPEN.md]] |
| 19 | 20 | |
| 20 | 21 | ## Mutation pattern and selective pressure estimates |
STAT3.md
| ... | ... | @@ -20,6 +20,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 20 | 20 | |
| 21 | 21 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 22 | 22 | |
| 23 | +### DLBCL |
|
| 23 | 24 | [[include:tables/DLBCL_STAT3.md]] |
| 24 | 25 | |
| 25 | 26 | ## Mutation pattern and selective pressure estimates |
STAT6.md
| ... | ... | @@ -23,7 +23,10 @@ Driver mutations affecting this gene in DLBCL/FL have been experimentally demons |
| 23 | 23 | |
| 24 | 24 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 25 | |
| 26 | +### DLBCL |
|
| 26 | 27 | [[include:tables/DLBCL_STAT6.md]] |
| 28 | + |
|
| 29 | +### FL |
|
| 27 | 30 | [[include:tables/FL_STAT6.md]] |
| 28 | 31 | |
| 29 | 32 | ## Mutation pattern and selective pressure estimates |
TAF1.md
| ... | ... | @@ -14,6 +14,7 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### DLBCL |
|
| 17 | 18 | [[include:tables/DLBCL_TAF1.md]] |
| 18 | 19 | |
| 19 | 20 | ## Mutation pattern and selective pressure estimates |
TBL1XR1.md
| ... | ... | @@ -18,7 +18,10 @@ Driver mutations affecting this gene in FL/DLBCL have been experimentally demons |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_TBL1XR1.md]] |
| 23 | + |
|
| 24 | +### FL |
|
| 22 | 25 | [[include:tables/FL_TBL1XR1.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
TCF3.md
| ... | ... | @@ -19,7 +19,10 @@ Driver mutations affecting this gene in BL have been experimentally demonstrated |
| 19 | 19 | |
| 20 | 20 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 21 | 21 | |
| 22 | +### DLBCL |
|
| 22 | 23 | [[include:tables/DLBCL_TCF3.md]] |
| 24 | + |
|
| 25 | +### BL |
|
| 23 | 26 | [[include:tables/BL_TCF3.md]] |
| 24 | 27 | |
| 25 | 28 | ## Mutation pattern and selective pressure estimates |
TCL1A.md
| ... | ... | @@ -15,7 +15,10 @@ nocite: | |
| 15 | 15 | |
| 16 | 16 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 17 | 17 | |
| 18 | +### DLBCL |
|
| 18 | 19 | [[include:tables/DLBCL_TCL1A.md]] |
| 20 | + |
|
| 21 | +### BL |
|
| 19 | 22 | [[include:tables/BL_TCL1A.md]] |
| 20 | 23 | |
| 21 | 24 | ## Mutation pattern and selective pressure estimates |
TET2.md
| ... | ... | @@ -19,6 +19,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 19 | 19 | |
| 20 | 20 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 21 | 21 | |
| 22 | +### DLBCL |
|
| 22 | 23 | [[include:tables/DLBCL_TET2.md]] |
| 23 | 24 | |
| 24 | 25 | ## Mutation pattern and selective pressure estimates |
TFAP4.md
| ... | ... | @@ -22,7 +22,10 @@ Driver mutations affecting this gene in BL have been experimentally demonstrated |
| 22 | 22 | |
| 23 | 23 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 24 | 24 | |
| 25 | +### DLBCL |
|
| 25 | 26 | [[include:tables/DLBCL_TFAP4.md]] |
| 27 | + |
|
| 28 | +### BL |
|
| 26 | 29 | [[include:tables/BL_TFAP4.md]] |
| 27 | 30 | |
| 28 | 31 | ## Mutation pattern and selective pressure estimates |
TMEM30A.md
| ... | ... | @@ -18,7 +18,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_TMEM30A.md]] |
| 23 | + |
|
| 24 | +### FL |
|
| 22 | 25 | [[include:tables/FL_TMEM30A.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
TMSB4X.md
| ... | ... | @@ -18,7 +18,10 @@ TMSB4X is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_TMSB4X.md]] |
| 23 | + |
|
| 24 | +### FL |
|
| 22 | 25 | [[include:tables/FL_TMSB4X.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
TNFAIP3.md
| ... | ... | @@ -18,7 +18,10 @@ Driver mutations affecting this gene in FL/DLBCL have been experimentally demons |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_TNFAIP3.md]] |
| 23 | + |
|
| 24 | +### FL |
|
| 22 | 25 | [[include:tables/FL_TNFAIP3.md]] |
| 23 | 26 | |
| 24 | 27 | ## Mutation pattern and selective pressure estimates |
TNFRSF14.md
| ... | ... | @@ -12,7 +12,7 @@ nocite: | |
| 12 | 12 | |
| 13 | 13 | ## Experimental Evidence |
| 14 | 14 | |
| 15 | -Driver mutations affecting this gene in DLBCL have been experimentally demonstrated to cause a reduction or loss of function (LOF).[@] |
|
| 15 | +Driver mutations affecting this gene in DLBCL have been experimentally demonstrated to cause a reduction or loss of function (LOF). |
|
| 16 | 16 | |
| 17 | 17 | ## Relevance tier by entity |
| 18 | 18 | |
| ... | ... | @@ -20,7 +20,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 20 | 20 | |
| 21 | 21 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 22 | 22 | |
| 23 | +### DLBCL |
|
| 23 | 24 | [[include:tables/DLBCL_TNFRSF14.md]] |
| 25 | + |
|
| 26 | +### FL |
|
| 24 | 27 | [[include:tables/FL_TNFRSF14.md]] |
| 25 | 28 | |
| 26 | 29 | ## Mutation pattern and selective pressure estimates |
TOX.md
| ... | ... | @@ -14,6 +14,7 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### DLBCL |
|
| 17 | 18 | [[include:tables/DLBCL_TOX.md]] |
| 18 | 19 | |
| 19 | 20 | ## Mutation pattern and selective pressure estimates |
TP53.md
| ... | ... | @@ -19,8 +19,13 @@ Driver mutations affecting this gene in BL/FL/DLBCL have been experimentally dem |
| 19 | 19 | |
| 20 | 20 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 21 | 21 | |
| 22 | +### DLBCL |
|
| 22 | 23 | [[include:tables/DLBCL_TP53.md]] |
| 24 | + |
|
| 25 | +### FL |
|
| 23 | 26 | [[include:tables/FL_TP53.md]] |
| 27 | + |
|
| 28 | +### BL |
|
| 24 | 29 | [[include:tables/BL_TP53.md]] |
| 25 | 30 | |
| 26 | 31 | ## Mutation pattern and selective pressure estimates |
UBE2A.md
| ... | ... | @@ -14,6 +14,7 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### DLBCL |
|
| 17 | 18 | [[include:tables/DLBCL_UBE2A.md]] |
| 18 | 19 | |
| 19 | 20 | ## Mutation pattern and selective pressure estimates |
USP7.md
| ... | ... | @@ -14,7 +14,10 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### DLBCL |
|
| 17 | 18 | [[include:tables/DLBCL_USP7.md]] |
| 19 | + |
|
| 20 | +### BL |
|
| 18 | 21 | [[include:tables/BL_USP7.md]] |
| 19 | 22 | |
| 20 | 23 | ## Mutation pattern and selective pressure estimates |
WEE1.md
| ... | ... | @@ -17,6 +17,7 @@ WEE1 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) |
| 17 | 17 | |
| 18 | 18 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 19 | 19 | |
| 20 | +### DLBCL |
|
| 20 | 21 | [[include:tables/DLBCL_WEE1.md]] |
| 21 | 22 | |
| 22 | 23 | ## Mutation pattern and selective pressure estimates |
WNK1.md
| ... | ... | @@ -14,7 +14,10 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### DLBCL |
|
| 17 | 18 | [[include:tables/DLBCL_WNK1.md]] |
| 19 | + |
|
| 20 | +### BL |
|
| 18 | 21 | [[include:tables/BL_WNK1.md]] |
| 19 | 22 | |
| 20 | 23 | ## Mutation pattern and selective pressure estimates |
XPO1.md
| ... | ... | @@ -19,6 +19,7 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 19 | 19 | |
| 20 | 20 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 21 | 21 | |
| 22 | +### DLBCL |
|
| 22 | 23 | [[include:tables/DLBCL_XPO1.md]] |
| 23 | 24 | |
| 24 | 25 | ## Mutation pattern and selective pressure estimates |
ZC3H12A.md
| ... | ... | @@ -18,7 +18,10 @@ Driver mutations affecting this gene in DLBCL have been experimentally demonstra |
| 18 | 18 | |
| 19 | 19 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 20 | 20 | |
| 21 | +### DLBCL |
|
| 21 | 22 | [[include:tables/DLBCL_ZC3H12A.md]] |
| 23 | + |
|
| 24 | +### FL |
|
| 22 | 25 | [[include:tables/FL_ZC3H12A.md]] |
| 23 | 26 | |
| 24 | 27 |
ZCCHC7.md
| ... | ... | @@ -14,6 +14,7 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### DLBCL |
|
| 17 | 18 | [[include:tables/DLBCL_ZCCHC7.md]] |
| 18 | 19 | |
| 19 | 20 |
ZFP36L1.md
| ... | ... | @@ -17,7 +17,10 @@ ZFP36L1 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ash |
| 17 | 17 | |
| 18 | 18 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 19 | 19 | |
| 20 | +### DLBCL |
|
| 20 | 21 | [[include:tables/DLBCL_ZFP36L1.md]] |
| 22 | + |
|
| 23 | +### BL |
|
| 21 | 24 | [[include:tables/BL_ZFP36L1.md]] |
| 22 | 25 | |
| 23 | 26 | ## Mutation pattern and selective pressure estimates |
ZNF217.md
| ... | ... | @@ -14,8 +14,13 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### DLBCL |
|
| 17 | 18 | [[include:tables/DLBCL_ZNF217.md]] |
| 19 | + |
|
| 20 | +### FL |
|
| 18 | 21 | [[include:tables/FL_ZNF217.md]] |
| 22 | + |
|
| 23 | +### BL |
|
| 19 | 24 | [[include:tables/BL_ZNF217.md]] |
| 20 | 25 | |
| 21 | 26 | ## Mutation pattern and selective pressure estimates |
ZNF229.md
| ... | ... | @@ -23,6 +23,7 @@ Due to [minimal support](ZNF229#representative-mutation) in the original primary |
| 23 | 23 | |
| 24 | 24 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 25 | 25 | |
| 26 | +### BL |
|
| 26 | 27 | [[include:tables/BL_ZNF229.md]] |
| 27 | 28 | |
| 28 | 29 | ## Mutation pattern and selective pressure estimates |
ZNF292.md
| ... | ... | @@ -14,6 +14,7 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### DLBCL |
|
| 17 | 18 | [[include:tables/DLBCL_ZNF292.md]] |
| 18 | 19 | |
| 19 | 20 | ## Mutation pattern and selective pressure estimates |
ZNF608.md
| ... | ... | @@ -14,7 +14,10 @@ nocite: | |
| 14 | 14 | |
| 15 | 15 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 16 | 16 | |
| 17 | +### DLBCL |
|
| 17 | 18 | [[include:tables/DLBCL_ZNF608.md]] |
| 19 | + |
|
| 20 | +### FL |
|
| 18 | 21 | [[include:tables/FL_ZNF608.md]] |
| 19 | 22 | |
| 20 | 23 | ## Mutation pattern and selective pressure estimates |