bdb732c26b0e377abf25ef4342ec4885aaf71650
DLBCL_genes.md
| ... | ... | @@ -16,30 +16,30 @@ link-citations: true |
| 16 | 16 | |Gene|Tier| First DLBCL evidence | Other entities | |
| 17 | 17 | |:-:|:-:|:--|:-| |
| 18 | 18 | |[ACTB](ACTB)|1|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@wienandGenomicAnalysesFlowsorted2019b]| |
| 19 | -|[ACTG1](ACTG1)|1|[Hubschmann et al](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@deschGenotypingCirculatingTumor2020; @spinaGeneticsNodalMarginal2016b]| |
|
| 20 | -|[ARID1A](ARID1A)|1|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@loveGeneticLandscapeMutations2012; @wienandGenomicAnalysesFlowsorted2019b; @krysiakRecurrentSomaticMutations2017b; @rossiCodingGenomeSplenic2012c]| |
|
| 19 | +|[ACTG1](ACTG1)|1|[Hubschmann et al](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@spinaGeneticsNodalMarginal2016b; @deschGenotypingCirculatingTumor2020]| |
|
| 20 | +|[ARID1A](ARID1A)|1|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@rossiCodingGenomeSplenic2012c; @wienandGenomicAnalysesFlowsorted2019b; @krysiakRecurrentSomaticMutations2017b; @loveGeneticLandscapeMutations2012]| |
|
| 21 | 21 | |[ATM](ATM)|1|[Reddy et al](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@beaLandscapeSomaticMutations2013; @braggioGenomicAnalysisMarginal2012]| |
| 22 | -|[B2M](B2M)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@pararajalingamCodingNoncodingDrivers2020; @reichelFlowSortingExome2015a]| |
|
| 23 | -|[BCL10](BCL10)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@spinaGeneticsNodalMarginal2016b; @russler-germainMutationsAssociatedProgression2023b]| |
|
| 22 | +|[B2M](B2M)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@reichelFlowSortingExome2015a; @pararajalingamCodingNoncodingDrivers2020]| |
|
| 23 | +|[BCL10](BCL10)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@russler-germainMutationsAssociatedProgression2023b; @spinaGeneticsNodalMarginal2016b]| |
|
| 24 | 24 | |[BCL2](BCL2)|1|[Tanaka et al](papers/tanakaFrequentIncidenceSomatic1992)[@tanakaFrequentIncidenceSomatic1992]|[@sarkozyMutationalLandscapeGray2021a; @burkhardtClinicalRelevanceMolecular2022b; @morinFrequentMutationHistonemodifying2011]| |
| 25 | 25 | |[BCL6](BCL6)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@loveGeneticLandscapeMutations2012]| |
| 26 | -|[BCL7A](BCL7A)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@krysiakRecurrentSomaticMutations2017b; @grandeGenomewideDiscoverySomatic2019; @reichelFlowSortingExome2015a]| |
|
| 26 | +|[BCL7A](BCL7A)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@krysiakRecurrentSomaticMutations2017b; @reichelFlowSortingExome2015a; @grandeGenomewideDiscoverySomatic2019]| |
|
| 27 | 27 | |[BIRC6](BIRC6)|1|[Reddy et al](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@sarkozyMutationalLandscapeGray2021a]| |
| 28 | 28 | |[BRAF](BRAF)|1|[Tiacci et al](papers/tiacciBRAFMutationsHairycell2011a)[@tiacciBRAFMutationsHairycell2011a]|[@loveGeneticLandscapeMutations2012]| |
| 29 | -|[BTG1](BTG1)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@sarkozyMutationalLandscapeGray2021a; @burkhardtClinicalRelevanceMolecular2022b]| |
|
| 29 | +|[BTG1](BTG1)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@burkhardtClinicalRelevanceMolecular2022b; @sarkozyMutationalLandscapeGray2021a]| |
|
| 30 | 30 | |[BTG2](BTG2)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@loveGeneticLandscapeMutations2012]| |
| 31 | 31 | |[BTK](BTK)|1|[Albuquerque et al](papers/albuquerqueEnhancingKnowledgeDiscovery2017a)[@albuquerqueEnhancingKnowledgeDiscovery2017a]|[@krysiakRecurrentSomaticMutations2017b]| |
| 32 | -|[CARD11](CARD11)|1|[Lenz et al](papers/lenzOncogenicCARD11Mutations2008)[@lenzOncogenicCARD11Mutations2008]|[@yanBCRTLRSignaling2012a; @morinFrequentMutationHistonemodifying2011; @wuGeneticHeterogeneityPrimary2016]| |
|
| 33 | -|[CCND3](CCND3)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@jalladesExomeSequencingIdentifies2017; @richterRecurrentMutationID32012a; @deschGenotypingCirculatingTumor2020]| |
|
| 32 | +|[CARD11](CARD11)|1|[Lenz et al](papers/lenzOncogenicCARD11Mutations2008)[@lenzOncogenicCARD11Mutations2008]|[@morinFrequentMutationHistonemodifying2011; @yanBCRTLRSignaling2012a; @wuGeneticHeterogeneityPrimary2016]| |
|
| 33 | +|[CCND3](CCND3)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@richterRecurrentMutationID32012a; @deschGenotypingCirculatingTumor2020; @jalladesExomeSequencingIdentifies2017]| |
|
| 34 | 34 | |[CD58](CD58)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@schneiderAlterationsCD58Gene2015a]| |
| 35 | 35 | |[CD70](CD70)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@russler-germainMutationsAssociatedProgression2023b]| |
| 36 | 36 | |[CD79B](CD79B)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019]| |
| 37 | -|[CD83](CD83)|1|[Morin et al](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@russler-germainMutationsAssociatedProgression2023b; @paneaWholeGenomeLandscape2019; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 37 | +|[CD83](CD83)|1|[Morin et al](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@russler-germainMutationsAssociatedProgression2023b; @dunsCharacterizationDLBCLPMBL2021b; @paneaWholeGenomeLandscape2019]| |
|
| 38 | 38 | |[CDKN2A](CDKN2A)|1|[Morin et al](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@spinaGeneticsNodalMarginal2016b; @grandeGenomewideDiscoverySomatic2019]| |
| 39 | -|[CREBBP](CREBBP)|1|[Pasqualucci et al](papers/pasqualucciInactivatingMutationsAcetyltransferase2011a)[@pasqualucciInactivatingMutationsAcetyltransferase2011a]|[@parryWholeExomeSequencing2013; @loveGeneticLandscapeMutations2012; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 39 | +|[CREBBP](CREBBP)|1|[Pasqualucci et al](papers/pasqualucciInactivatingMutationsAcetyltransferase2011a)[@pasqualucciInactivatingMutationsAcetyltransferase2011a]|[@parryWholeExomeSequencing2013; @dunsCharacterizationDLBCLPMBL2021b; @loveGeneticLandscapeMutations2012]| |
|
| 40 | 40 | |[CXCR4](CXCR4)|1|[Khodabakhshi et al](papers/khodabakhshiRecurrentTargetsAberrant2012)[@khodabakhshiRecurrentTargetsAberrant2012]|[@krysiakRecurrentSomaticMutations2017b; @paneaWholeGenomeLandscape2019]| |
| 41 | 41 | |[CXCR5](CXCR5)|1|[Schmitz et al](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|[@mottokIntegrativeGenomicAnalysis2019b]| |
| 42 | -|[DDX3X](DDX3X)|1|[Reddy et al](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@mottokIntegrativeGenomicAnalysis2019b; @schmitzBurkittLymphomaPathogenesis2012]| |
|
| 42 | +|[DDX3X](DDX3X)|1|[Reddy et al](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@schmitzBurkittLymphomaPathogenesis2012; @mottokIntegrativeGenomicAnalysis2019b]| |
|
| 43 | 43 | |[DTX1](DTX1)|1|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@loveGeneticLandscapeMutations2012; @gomezUltraDeepSequencingReveals2023; @rossiCodingGenomeSplenic2012c]| |
| 44 | 44 | |[DUSP2](DUSP2)|1|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@dunsCharacterizationDLBCLPMBL2021b]| |
| 45 | 45 | |[EBF1](EBF1)|1|[Bohle et al](papers/bohleRoleEarlyBcell2013)[@bohleRoleEarlyBcell2013]|[@thomasGeneticSubgroupsInform2023; @reichelFlowSortingExome2015a]| |
| ... | ... | @@ -52,14 +52,14 @@ link-citations: true |
| 52 | 52 | |[FBXO11](FBXO11)|1|[Hubschmann et al](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@parryWholeExomeSequencing2013; @richterRecurrentMutationID32012a]| |
| 53 | 53 | |[FBXW7](FBXW7)|1|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|| |
| 54 | 54 | |[FOXO1](FOXO1)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@dunsCharacterizationDLBCLPMBL2021b; @schmitzBurkittLymphomaPathogenesis2012]| |
| 55 | -|[GNA13](GNA13)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@loveGeneticLandscapeMutations2012; @reichelFlowSortingExome2015a]| |
|
| 55 | +|[GNA13](GNA13)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@reichelFlowSortingExome2015a; @loveGeneticLandscapeMutations2012]| |
|
| 56 | 56 | |[GNAI2](GNAI2)|1|[Morin et al](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@grandeGenomewideDiscoverySomatic2019]| |
| 57 | 57 | |[GRB2](GRB2)|1|[Pasqualucci et al](papers/pasqualucciAnalysisCodingGenome2011)[@pasqualucciAnalysisCodingGenome2011]|| |
| 58 | 58 | |[GRHPR](GRHPR)|1|[Arthur et al](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
| 59 | -|[HIST1H1B](HIST1H1B)|1|[Chapuy et al](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|[@sarkozyMutationalLandscapeGray2021a; @krysiakRecurrentSomaticMutations2017b]| |
|
| 59 | +|[HIST1H1B](HIST1H1B)|1|[Chapuy et al](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|[@krysiakRecurrentSomaticMutations2017b; @sarkozyMutationalLandscapeGray2021a]| |
|
| 60 | 60 | |[HIST1H1C](HIST1H1C)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019]| |
| 61 | -|[HIST1H1D](HIST1H1D)|1|[Morin et al](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@krysiakRecurrentSomaticMutations2017b; @jalladesExomeSequencingIdentifies2017]| |
|
| 62 | -|[HIST1H1E](HIST1H1E)|1|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@reichelFlowSortingExome2015a; @grandeGenomewideDiscoverySomatic2019; @krysiakRecurrentSomaticMutations2017b]| |
|
| 61 | +|[HIST1H1D](HIST1H1D)|1|[Morin et al](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@jalladesExomeSequencingIdentifies2017; @krysiakRecurrentSomaticMutations2017b]| |
|
| 62 | +|[HIST1H1E](HIST1H1E)|1|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@krysiakRecurrentSomaticMutations2017b; @reichelFlowSortingExome2015a; @grandeGenomewideDiscoverySomatic2019]| |
|
| 63 | 63 | |[HIST1H2AC](HIST1H2AC)|1|[Morin et al](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@krysiakRecurrentSomaticMutations2017b]| |
| 64 | 64 | |[HIST1H2AM](HIST1H2AM)|1|[Chapuy et al](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|[@krysiakRecurrentSomaticMutations2017b; @paneaWholeGenomeLandscape2019]| |
| 65 | 65 | |[HIST1H2BC](HIST1H2BC)|1|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@krysiakRecurrentSomaticMutations2017b; @mottokIntegrativeGenomicAnalysis2019b]| |
| ... | ... | @@ -75,14 +75,14 @@ link-citations: true |
| 75 | 75 | |[IKZF3](IKZF3)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019]| |
| 76 | 76 | |[IL4R](IL4R)|1|[Duns et al](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|[@viganoSomaticIL4RMutations2018b]| |
| 77 | 77 | |[IRF4](IRF4)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@mottokIntegrativeGenomicAnalysis2019b]| |
| 78 | -|[IRF8](IRF8)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@mottokIntegrativeGenomicAnalysis2019b; @paneaWholeGenomeLandscape2019]| |
|
| 78 | +|[IRF8](IRF8)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019; @mottokIntegrativeGenomicAnalysis2019b]| |
|
| 79 | 79 | |[ITPKB](ITPKB)|1|[Schmitz et al](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|[@reichelFlowSortingExome2015a]| |
| 80 | 80 | |[JUNB](JUNB)|1|[Reddy et al](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@mottokIntegrativeGenomicAnalysis2019b]| |
| 81 | 81 | |[KLF2](KLF2)|1|[Pasqualucci et al](papers/pasqualucciAnalysisCodingGenome2011)[@pasqualucciAnalysisCodingGenome2011]|[@jalladesExomeSequencingIdentifies2017; @deschGenotypingCirculatingTumor2020]| |
| 82 | 82 | |[KLHL14](KLHL14)|1|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|| |
| 83 | 83 | |[KLHL6](KLHL6)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@ganapathiGeneticLandscapeDural2016]| |
| 84 | -|[KMT2C](KMT2C)|1|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@sarkozyMutationalLandscapeGray2021a; @zhangGenomicLandscapeMantle2014; @zhouSporadicEndemicBurkitt2019]| |
|
| 85 | -|[KMT2D](KMT2D)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@beaLandscapeSomaticMutations2013; @grandeGenomewideDiscoverySomatic2019; @rossiCodingGenomeSplenic2012c; @deschGenotypingCirculatingTumor2020]| |
|
| 84 | +|[KMT2C](KMT2C)|1|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@zhouSporadicEndemicBurkitt2019; @sarkozyMutationalLandscapeGray2021a; @zhangGenomicLandscapeMantle2014]| |
|
| 85 | +|[KMT2D](KMT2D)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@deschGenotypingCirculatingTumor2020; @rossiCodingGenomeSplenic2012c; @beaLandscapeSomaticMutations2013; @grandeGenomewideDiscoverySomatic2019]| |
|
| 86 | 86 | |[KRAS](KRAS)|1|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
| 87 | 87 | |[LCOR](LCOR)|1|[Arthur et al](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
| 88 | 88 | |[LRRN3](LRRN3)|1|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@sarkozyMutationalLandscapeGray2021a]| |
| ... | ... | @@ -93,17 +93,17 @@ link-citations: true |
| 93 | 93 | |[MPEG1](MPEG1)|1|[Morin et al](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
| 94 | 94 | |[MS4A1](MS4A1)|1|[Rushton et al](papers/rushtonGeneticEvolutionaryPatterns2020)[@rushtonGeneticEvolutionaryPatterns2020]|[@mottokIntegrativeGenomicAnalysis2019b]| |
| 95 | 95 | |[MTOR](MTOR)|1|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@paneaWholeGenomeLandscape2019]| |
| 96 | -|[MYC](MYC)|1|[Pasqualucci et al](papers/pasqualucciHypermutationMultipleProtooncogenes2001a)[@pasqualucciHypermutationMultipleProtooncogenes2001a]|[@dunsCharacterizationDLBCLPMBL2021b; @jalladesExomeSequencingIdentifies2017; @johnstonCmycHypermutationBurkitt1992]| |
|
| 96 | +|[MYC](MYC)|1|[Pasqualucci et al](papers/pasqualucciHypermutationMultipleProtooncogenes2001a)[@pasqualucciHypermutationMultipleProtooncogenes2001a]|[@jalladesExomeSequencingIdentifies2017; @johnstonCmycHypermutationBurkitt1992; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 97 | 97 | |[MYD88](MYD88)|1|[Ngo et al](papers/ngoOncogenicallyActiveMYD882011a)[@ngoOncogenicallyActiveMYD882011a]|[@yanBCRTLRSignaling2012a]| |
| 98 | 98 | |[NFKBIA](NFKBIA)|1|[Lake et al](papers/lakeMutationsNFKBIAEncoding2009)[@lakeMutationsNFKBIAEncoding2009]|[@russler-germainMutationsAssociatedProgression2023b; @wienandGenomicAnalysesFlowsorted2019b]| |
| 99 | -|[NFKBIE](NFKBIE)|1|[Morin et al](papers/morinGeneticLandscapesRelapsed2016)[@morinGeneticLandscapesRelapsed2016]|[@mansouriFrequentNFKBIEDeletions2016; @pararajalingamCodingNoncodingDrivers2020]| |
|
| 99 | +|[NFKBIE](NFKBIE)|1|[Morin et al](papers/morinGeneticLandscapesRelapsed2016)[@morinGeneticLandscapesRelapsed2016]|[@pararajalingamCodingNoncodingDrivers2020; @mansouriFrequentNFKBIEDeletions2016]| |
|
| 100 | 100 | |[NFKBIZ](NFKBIZ)|1|[Morin et al](papers/morinGeneticLandscapesRelapsed2016)[@morinGeneticLandscapesRelapsed2016]|| |
| 101 | 101 | |[NOL9](NOL9)|1|[Schmitz et al](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|[@spinaGeneticsNodalMarginal2016b]| |
| 102 | -|[NOTCH1](NOTCH1)|1|[Pasqualucci et al](papers/pasqualucciAnalysisCodingGenome2011)[@pasqualucciAnalysisCodingGenome2011]|[@loveGeneticLandscapeMutations2012; @beaLandscapeSomaticMutations2013; @rossiCodingGenomeSplenic2012c]| |
|
| 103 | -|[NOTCH2](NOTCH2)|1|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@rossiCodingGenomeSplenic2012c; @beaLandscapeSomaticMutations2013]| |
|
| 102 | +|[NOTCH1](NOTCH1)|1|[Pasqualucci et al](papers/pasqualucciAnalysisCodingGenome2011)[@pasqualucciAnalysisCodingGenome2011]|[@beaLandscapeSomaticMutations2013; @loveGeneticLandscapeMutations2012; @rossiCodingGenomeSplenic2012c]| |
|
| 103 | +|[NOTCH2](NOTCH2)|1|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@beaLandscapeSomaticMutations2013; @rossiCodingGenomeSplenic2012c]| |
|
| 104 | 104 | |[OSBPL10](OSBPL10)|1|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|| |
| 105 | 105 | |[P2RY8](P2RY8)|1|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@muppidiLossSignalingGa132014b]| |
| 106 | -|[PIM1](PIM1)|1|[Pasqualucci et al](papers/pasqualucciHypermutationMultipleProtooncogenes2001a)[@pasqualucciHypermutationMultipleProtooncogenes2001a]|[@burkhardtClinicalRelevanceMolecular2022b; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 106 | +|[PIM1](PIM1)|1|[Pasqualucci et al](papers/pasqualucciHypermutationMultipleProtooncogenes2001a)[@pasqualucciHypermutationMultipleProtooncogenes2001a]|[@dunsCharacterizationDLBCLPMBL2021b; @burkhardtClinicalRelevanceMolecular2022b]| |
|
| 107 | 107 | |[PIM2](PIM2)|1|[Arthur et al](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|[@reichelFlowSortingExome2015a]| |
| 108 | 108 | |[POU2AF1](POU2AF1)|1|[Chapuy et al](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|[@krysiakRecurrentSomaticMutations2017b]| |
| 109 | 109 | |[POU2F2](POU2F2)|1|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@krysiakRecurrentSomaticMutations2017b]| |
| ... | ... | @@ -121,18 +121,18 @@ link-citations: true |
| 121 | 121 | |[SIN3A](SIN3A)|1|[Chapuy et al](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|[@rossiCodingGenomeSplenic2012c; @grandeGenomewideDiscoverySomatic2019]| |
| 122 | 122 | |[SMARCA4](SMARCA4)|1|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@richterRecurrentMutationID32012a; @krysiakRecurrentSomaticMutations2017b; @nadeuGenomicEpigenomicInsights2020b]| |
| 123 | 123 | |[SOCS1](SOCS1)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@wenigerMutationsTumorSuppressor2006a]| |
| 124 | -|[SPEN](SPEN)|1|[Albuquerque et al](papers/albuquerqueEnhancingKnowledgeDiscovery2017a)[@albuquerqueEnhancingKnowledgeDiscovery2017a]|[@rossiCodingGenomeSplenic2012c; @sarkozyMutationalLandscapeGray2021a]| |
|
| 124 | +|[SPEN](SPEN)|1|[Albuquerque et al](papers/albuquerqueEnhancingKnowledgeDiscovery2017a)[@albuquerqueEnhancingKnowledgeDiscovery2017a]|[@sarkozyMutationalLandscapeGray2021a; @rossiCodingGenomeSplenic2012c]| |
|
| 125 | 125 | |[STAT3](STAT3)|1|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
| 126 | 126 | |[STAT6](STAT6)|1|[Yildiz et al](papers/yildizActivatingSTAT6Mutations2015c)[@yildizActivatingSTAT6Mutations2015c]|[@ritzRecurrentMutationsSTAT62009a]| |
| 127 | 127 | |[TAF1](TAF1)|1|[Morin et al](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@spinaGeneticsNodalMarginal2016b]| |
| 128 | 128 | |[TBL1XR1](TBL1XR1)|1|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@rossiCodingGenomeSplenic2012c]| |
| 129 | 129 | |[TET2](TET2)|1|[Albuquerque et al](papers/albuquerqueEnhancingKnowledgeDiscovery2017a)[@albuquerqueEnhancingKnowledgeDiscovery2017a]|[@thomasGeneticSubgroupsInform2023]| |
| 130 | 130 | |[TMEM30A](TMEM30A)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|| |
| 131 | -|[TMSB4X](TMSB4X)|1|[Albuquerque et al](papers/albuquerqueEnhancingKnowledgeDiscovery2017a)[@albuquerqueEnhancingKnowledgeDiscovery2017a]|| |
|
| 131 | +|[TMSB4X](TMSB4X)|1|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 132 | 132 | |[TNFAIP3](TNFAIP3)|1|[Compagno et al](papers/compagnoMutationsMultipleGenes2009a)[@compagnoMutationsMultipleGenes2009a]|[@schmitzTNFAIP3A20Tumor2009a; @rossiAlterationBIRC3Multiple2011a]| |
| 133 | -|[TNFRSF14](TNFRSF14)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@cheungAcquiredTNFRSF14Mutations2010a; @spinaGeneticsNodalMarginal2016b]| |
|
| 133 | +|[TNFRSF14](TNFRSF14)|1|[Morin et al](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@spinaGeneticsNodalMarginal2016b; @cheungAcquiredTNFRSF14Mutations2010a]| |
|
| 134 | 134 | |[TOX](TOX)|1|[Reddy et al](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
| 135 | -|[TP53](TP53)|1|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@beaLandscapeSomaticMutations2013; @morinFrequentMutationHistonemodifying2011; @tiacciPervasiveMutationsJAKSTAT2018b; @wildaInactivationARFMDM2p53Pathway2004; @rossiCodingGenomeSplenic2012c]| |
|
| 135 | +|[TP53](TP53)|1|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@beaLandscapeSomaticMutations2013; @wildaInactivationARFMDM2p53Pathway2004; @morinFrequentMutationHistonemodifying2011; @tiacciPervasiveMutationsJAKSTAT2018b; @rossiCodingGenomeSplenic2012c]| |
|
| 136 | 136 | |[UBE2A](UBE2A)|1|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@reichelFlowSortingExome2015a]| |
| 137 | 137 | |[WEE1](WEE1)|1|[Schmitz et al](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|[@reichelFlowSortingExome2015a]| |
| 138 | 138 | |[XPO1](XPO1)|1|[Mareschal et al](papers/mareschalWholeExomeSequencing2016)[@mareschalWholeExomeSequencing2016]|[@jardinRecurrentMutationsExportin2016a]| |
| ... | ... | @@ -158,7 +158,7 @@ link-citations: true |
| 158 | 158 | |[BCL11A](BCL11A)|2|[Chapuy et al](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
| 159 | 159 | |[BCOR](BCOR)|2||[@jalladesExomeSequencingIdentifies2017; @nadeuGenomicEpigenomicInsights2020b]| |
| 160 | 160 | |[BCR](BCR)|2|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
| 161 | -|[BIRC3](BIRC3)|2|[Arthur et al](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|[@beaLandscapeSomaticMutations2013; @dunsCharacterizationDLBCLPMBL2021b; @rossiAlterationBIRC3Multiple2011a]| |
|
| 161 | +|[BIRC3](BIRC3)|2|[Arthur et al](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|[@rossiAlterationBIRC3Multiple2011a; @beaLandscapeSomaticMutations2013; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 162 | 162 | |[BLK](BLK)|2||| |
| 163 | 163 | |[BRINP3](BRINP3)|2|[Reddy et al](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
| 164 | 164 | |[BTBD3](BTBD3)|2|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|| |
| ... | ... | @@ -213,8 +213,8 @@ link-citations: true |
| 213 | 213 | |[HNRNPH1](HNRNPH1)|2|[Pararajalingam et al](papers/pararajalingamCodingNoncodingDrivers2020)[@pararajalingamCodingNoncodingDrivers2020]|| |
| 214 | 214 | |[ID3](ID3)|2|[Schmitz et al](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|[@richterRecurrentMutationID32012a; @spinaGeneticsNodalMarginal2016b]| |
| 215 | 215 | |[IFNGR1](IFNGR1)|2|[Morin et al](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
| 216 | -|[IGLL5](IGLL5)|2|[Chapuy et al](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|[@deschGenotypingCirculatingTumor2020; @russler-germainMutationsAssociatedProgression2023b; @paneaWholeGenomeLandscape2019]| |
|
| 217 | -|[IKBKB](IKBKB)|2|[Reddy et al](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@rossiAlterationBIRC3Multiple2011a; @wienandGenomicAnalysesFlowsorted2019b]| |
|
| 216 | +|[IGLL5](IGLL5)|2|[Chapuy et al](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|[@russler-germainMutationsAssociatedProgression2023b; @deschGenotypingCirculatingTumor2020; @paneaWholeGenomeLandscape2019]| |
|
| 217 | +|[IKBKB](IKBKB)|2|[Reddy et al](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@wienandGenomicAnalysesFlowsorted2019b; @rossiAlterationBIRC3Multiple2011a]| |
|
| 218 | 218 | |[IKBKE](IKBKE)|2|[Hubschmann et al](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
| 219 | 219 | |[IL16](IL16)|2|[Reddy et al](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
| 220 | 220 | |[IL6](IL6)|2|[Chapuy et al](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
| ... | ... | @@ -245,7 +245,7 @@ link-citations: true |
| 245 | 245 | |[MYOM2](MYOM2)|2|[Pasqualucci et al](papers/pasqualucciAnalysisCodingGenome2011)[@pasqualucciAnalysisCodingGenome2011]|| |
| 246 | 246 | |[NAV1](NAV1)|2|[Chapuy et al](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
| 247 | 247 | |[NCOA3](NCOA3)|2||| |
| 248 | -|[NCOR2](NCOR2)|2||[@spinaGeneticsNodalMarginal2016b; @sarkozyMutationalLandscapeGray2021a; @schmitzBurkittLymphomaPathogenesis2012]| |
|
| 248 | +|[NCOR2](NCOR2)|2||[@spinaGeneticsNodalMarginal2016b; @schmitzBurkittLymphomaPathogenesis2012; @sarkozyMutationalLandscapeGray2021a]| |
|
| 249 | 249 | |[NEAT1](NEAT1)|2|[Arthur et al](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
| 250 | 250 | |[NF1](NF1)|2|[Zhang et al](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|| |
| 251 | 251 | |[NFKB1](NFKB1)|2||| |
| ... | ... | @@ -319,7 +319,7 @@ link-citations: true |
| 319 | 319 | |[UNC5D](UNC5D)|2|[Lohr et al](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
| 320 | 320 | |[USP7](USP7)|2|[Arthur et al](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|[@grandeGenomewideDiscoverySomatic2019]| |
| 321 | 321 | |[WDFY3](WDFY3)|2|[Morin et al](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
| 322 | -|[WNK1](WNK1)|2|[Hubschmann et al](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@thomasGeneticSubgroupsInform2023; @jalladesExomeSequencingIdentifies2017]| |
|
| 322 | +|[WNK1](WNK1)|2|[Hubschmann et al](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@jalladesExomeSequencingIdentifies2017; @thomasGeneticSubgroupsInform2023]| |
|
| 323 | 323 | |[XBP1](XBP1)|2||| |
| 324 | 324 | |[YY1](YY1)|2|[Reddy et al](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
| 325 | 325 | |[ZCCHC7](ZCCHC7)|2|[Arthur et al](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
TMSB4X.md
| ... | ... | @@ -14,7 +14,11 @@ TMSB4X is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm |
| 14 | 14 | %%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%% |
| 15 | 15 | timeline |
| 16 | 16 | title Publication timing |
| 17 | - 2017-05-01 : Albuquerque : DLBCL |
|
| 17 | +2013-01-01 : Zhang : DLBCL |
|
| 18 | +2017-05-01 : Albuquerque : DLBCL |
|
| 19 | +2017-10-10 : Reddy : DLBCL |
|
| 20 | +2018-04-12 : Schmitz : DLBCL |
|
| 21 | +2018-05-01 : Chapuy : DLBCL |
|
| 18 | 22 | ``` |
| 19 | 23 | |
| 20 | 24 | ## Relevance tier by entity |
| ... | ... | @@ -22,7 +26,7 @@ timeline |
| 22 | 26 | |Entity|Tier|Description | |
| 23 | 27 | |:------:|:----:|--------------------------------------| |
| 24 | 28 | ||1|high-confidence PMBL/cHL/GZL gene| |
| 25 | -| |1-a | aSHM target and high-confidence DLBCL gene [@albuquerqueEnhancingKnowledgeDiscovery2017a]| |
|
| 29 | +| |1-a | aSHM target and high-confidence DLBCL gene [@zhangGeneticHeterogeneityDiffuse2013; @albuquerqueEnhancingKnowledgeDiscovery2017a]| |
|
| 26 | 30 | | |1-a | aSHM target and high-confidence FL gene | |
| 27 | 31 | |
| 28 | 32 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |