c0ee1e6489bee0c6c12750cf6b0c187488430530
STAT6.md
| ... | ... | @@ -5,6 +5,8 @@ link-citations: true |
| 5 | 5 | --- |
| 6 | 6 | # STAT6 |
| 7 | 7 | |
| 8 | +[[_TOC_]] |
|
| 9 | + |
|
| 8 | 10 | ## Overview |
| 9 | 11 | The STAT6 gene, which encodes a transcription factor involved in the JAK-STAT signaling pathway, plays a significant role in the pathogenesis of various lymphomas, including diffuse large B-cell lymphoma (DLBCL). Below is a summary of the common mutations in the STAT6 gene identified in DLBCL. Mutations in the DNA binding domain of STAT6 are common in PMBCL and more rare in DLBCL. |
| 10 | 12 |