NOTCH1.md
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|Entity|Tier|Description |
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|:------:|:----:|--------------------------------------|
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|![MZL](images/icons/MZL_tier1.png)|1|high-confidence MZL gene|
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-|![BL](images/icons/BL_tier2.png) |2 |relevance in BL is unlikely|
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+|![BL](images/icons/BL_tier2.png) |2-F |Failed QC|
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|![DLBCL](images/icons/DLBCL_tier1.png) |1 |high-confidence DLBCL gene |
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|![MCL](images/icons/MCL_tier1.png) |1 |high-confidence MCL gene |
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@@ -77,6 +77,16 @@ View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/N
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**Rating**
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★ ☆ ☆ ☆ ☆
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+## All Mutations
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+
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+### BL<sup>3</sup>
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+
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+[1061](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Love/1061_reports.html)
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+[1096](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Love/1096_reports.html)
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+[324](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Love/324_reports.html)
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+[508](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Love/508_reports.html)
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+[513](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Love/513_reports.html)
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+
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## References
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1. Pasqualucci L, Trifonov V, Fabbri G, Ma J, Rossi D, Chiarenza A, Wells VA, Grunn A, Messina M, Elliot O, Chan J, Bhagat G, Chadburn A, Gaidano G, Mullighan CG, Rabadan R, Dalla-Favera R. Analysis of the coding genome of diffuse large B-cell lymphoma. Nat Genet. 2011 Jul 31;43(9):830–837. PMCID: PMC3297422
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2. Rossi D, Trifonov V, Fangazio M, Bruscaggin A, Rasi S, Spina V, Monti S, Vaisitti T, Arruga F, Famà R, Ciardullo C, Greco M, Cresta S, Piranda D, Holmes A, Fabbri G, Messina M, Rinaldi A, Wang J, Agostinelli C, Piccaluga PP, Lucioni M, Tabbò F, Serra R, Franceschetti S, Deambrogi C, Daniele G, Gattei V, Marasca R, Facchetti F, Arcaini L, Inghirami G, Bertoni F, Pileri SA, Deaglio S, Foà R, Dalla-Favera R, Pasqualucci L, Rabadan R, Gaidano G. The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development. J Exp Med. 2012 Aug 27;209(9):1537–1551. PMCID: PMC3428941