c8bd4db89c04da9328d97274294d18e2638d3a31
HLA-A.md
| ... | ... | @@ -26,15 +26,15 @@ timeline |
| 26 | 26 | |
| 27 | 27 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 28 | 28 | |
| 29 | -|Entity|source |frequency (%)| |
|
| 30 | -|:------:|:---------------------:|:-------------:| |
|
| 31 | -|DLBCL |GAMBL genomes | 7.46 | |
|
| 32 | -|DLBCL |Schmitz cohort |11.06 | |
|
| 33 | -|DLBCL |Reddy cohort | 0.20 | |
|
| 34 | -|DLBCL |Chapuy cohort | 8.97 | |
|
| 35 | -|BL |GAMBL genomes+capture| 1.39 | |
|
| 36 | -|BL |Thomas cohort | 1.30 | |
|
| 37 | -|BL |Panea cohort | NA | |
|
| 29 | +|Entity |Samples/Cohort |Incidence estimate (95% CI) | |
|
| 30 | +|:------|:-------------------|:---------------------------| |
|
| 31 | +|DLBCL |GAMBL without Reddy |0.0985 [0.0808,0.1163] | |
|
| 32 | +|DLBCL |GAMBL best Reddy |0.0112 [0.0062,0.0162] | |
|
| 33 | +|DLBCL |BC |0.0987 [0.0595,0.1378] | |
|
| 34 | +|DLBCL |Dana-Farber |0.0924 [0.0598,0.125] | |
|
| 35 | +|DLBCL |NCI |0.1106 [0.0823,0.139] | |
|
| 36 | +|DLBCL |Reddy |0.0037 [0,0.0089] | |
|
| 37 | +|DLBCL |DLBCL_ICGC |0.0706 [0.0161,0.125] | |
|
| 38 | 38 | |
| 39 | 39 | ## Mutation pattern and selective pressure estimates |
| 40 | 40 |