cd60cf6ba15f6632fbaa7abfb09aeece32a35cda
ACAD9.md
| ... | ... | @@ -27,11 +27,7 @@ Due to [minimal support](ACAD9#representative-mutation) in the original primary |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |No |No |2.358 |0 | |
|
| 33 | -|DLBCL |No |No |0.000 |0 | |
|
| 34 | -|FL |No |No |5.352 |0 | |
|
| 30 | +[[include:dnds_ACAD9.md]] |
|
| 35 | 31 | |
| 36 | 32 | |
| 37 | 33 |
ACE.md
| ... | ... | @@ -29,11 +29,7 @@ Due to [minimal support](ACE#representative-mutation) in the original primary da |
| 29 | 29 | |
| 30 | 30 | ## Mutation pattern and selective pressure estimates |
| 31 | 31 | |
| 32 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 33 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 34 | -|BL |No |No |3.943 |0 | |
|
| 35 | -|DLBCL |No |No |0.545 |0 | |
|
| 36 | -|FL |No |No |1.256 |0 | |
|
| 32 | +[[include:dnds_ACE.md]] |
|
| 37 | 33 | |
| 38 | 34 | |
| 39 | 35 |
ADAMTS1.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL in 2021 by Hübschmann et a |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |1.907 |0.000 | |
|
| 31 | -|DLBCL |No |No |0.524 |7.778 | |
|
| 32 | -|FL |No |No |0.000 |0.000 | |
|
| 28 | +[[include:dnds_ADAMTS1.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
ADAMTS5.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |No |1.451 |5.235 | |
|
| 26 | -|DLBCL |No |No |3.276 |0.000 | |
|
| 27 | -|FL |No |No |2.666 |0.000 | |
|
| 23 | +[[include:dnds_ADAMTS5.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/ADAMTS5_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/ADAMTS5_protein_hg38.html) |
ADNP.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |1.200 |17.917 | |
|
| 28 | -|DLBCL |No |No |1.866 | 0.000 | |
|
| 29 | -|FL |No |No |2.254 | 0.000 | |
|
| 25 | +[[include:dnds_ADNP.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
AGO4.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |1.183 | 0.000 | |
|
| 28 | -|DLBCL |No |No |0.000 |11.202 | |
|
| 29 | -|FL |No |No |0.000 | 0.000 | |
|
| 25 | +[[include:dnds_AGO4.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
AICDA.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |Yes |No |2.589 |0 | |
|
| 29 | -|DLBCL |Yes |No |2.652 |0 | |
|
| 30 | -|FL |Yes |No |4.955 |0 | |
|
| 26 | +[[include:dnds_AICDA.md]] |
|
| 31 | 27 | |
| 32 | 28 | ## aSHM regions |
| 33 | 29 |
ALPK2.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |1.951 |0 | |
|
| 30 | -|DLBCL |No |No |0.000 |0 | |
|
| 31 | -|FL |No |No |1.538 |0 | |
|
| 27 | +[[include:dnds_ALPK2.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
ANK2.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |No |1.169 |1.1 | |
|
| 26 | -|DLBCL |No |No |0.393 |0.0 | |
|
| 27 | -|FL |No |No |0.340 |0.0 | |
|
| 23 | +[[include:dnds_ANK2.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 |
ANKRD12.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL in 2021 by Hübschmann et a |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |1.649 |0.000 | |
|
| 31 | -|DLBCL |No |No |0.885 |4.832 | |
|
| 32 | -|FL |No |No |0.000 |0.000 | |
|
| 28 | +[[include:dnds_ANKRD12.md]] |
|
| 33 | 29 | |
| 34 | 30 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/ANKRD12_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/ANKRD12_protein_hg38.html) |
| 35 | 31 |
ANKRD17.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |2.047 |8.897 | |
|
| 29 | -|DLBCL |No |No |1.492 |4.437 | |
|
| 30 | -|FL |No |No |0.000 |0.000 | |
|
| 26 | +[[include:dnds_ANKRD17.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/ANKRD17_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/ANKRD17_protein_hg38.html) |
ARHGEF1.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |2.954 |0.000 | |
|
| 28 | -|DLBCL |No |No |2.662 |9.372 | |
|
| 29 | -|FL |No |No |3.865 |0.000 | |
|
| 25 | +[[include:dnds_ARHGEF1.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
ARID1B.md
| ... | ... | @@ -29,11 +29,7 @@ link-citations: true |
| 29 | 29 | |
| 30 | 30 | ## Mutation pattern and selective pressure estimates |
| 31 | 31 | |
| 32 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 33 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 34 | -|BL |No |No |0.659 | 4.236 | |
|
| 35 | -|DLBCL |No |No |0.969 |13.782 | |
|
| 36 | -|FL |No |No |0.747 |11.009 | |
|
| 32 | +[[include:dnds_ARID1B.md]] |
|
| 37 | 33 | |
| 38 | 34 | |
| 39 | 35 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/ARID1B_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/ARID1B_protein_hg38.html) |
ARID5B.md
| ... | ... | @@ -27,11 +27,7 @@ link-citations: true |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |No |No |0.378 |0 | |
|
| 33 | -|DLBCL |No |No |2.263 |0 | |
|
| 34 | -|FL |No |No |0.000 |0 | |
|
| 30 | +[[include:dnds_ARID5B.md]] |
|
| 35 | 31 | |
| 36 | 32 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/ARID5B_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/ARID5B_protein_hg38.html) |
| 37 | 33 |
ATP2C2.md
| ... | ... | @@ -28,11 +28,7 @@ Due to [minimal support](ATP2C2#representative-mutation) in the original primary |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |No |No |0.473 |0 | |
|
| 34 | -|DLBCL |No |No |0.000 |0 | |
|
| 35 | -|FL |No |No |3.759 |0 | |
|
| 31 | +[[include:dnds_ATP2C2.md]] |
|
| 36 | 32 | |
| 37 | 33 | |
| 38 | 34 |
ATP6V1A.md
| ... | ... | @@ -22,11 +22,7 @@ Mutations in this gene were first described in DLBCL in 2021 by Hübschmann et a |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |1.321 |0 | |
|
| 28 | -|DLBCL |No |No |7.648 |0 | |
|
| 29 | -|FL |No |No |8.783 |0 | |
|
| 25 | +[[include:dnds_ATP6V1A.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 | ## ATP6V1A Hotspots |
ATR.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.<sup |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |0.459 |0.000 | |
|
| 31 | -|DLBCL |No |No |1.146 |3.261 | |
|
| 32 | -|FL |No |No |0.000 |0.000 | |
|
| 28 | +[[include:dnds_ATR.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/ATR_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/ATR_protein_hg38.html) |
BCL11A.md
| ... | ... | @@ -28,11 +28,7 @@ BCL11A (B-cell lymphoma/leukemia 11A) is a transcription factor involved in the |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |Yes |No |4.455 | 0.000 | |
|
| 34 | -|DLBCL |Yes |Yes |5.279 |69.578 | |
|
| 35 | -|FL |Yes |No |1.180 | 0.000 | |
|
| 31 | +[[include:dnds_BCL11A.md]] |
|
| 36 | 32 | |
| 37 | 33 | ## aSHM regions |
| 38 | 34 |
BCR.md
| ... | ... | @@ -28,11 +28,7 @@ BCR (Breakpoint Cluster Region Protein) is one of [a number of genes](https://gi |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |Yes |No |2.733 |2.641 | |
|
| 34 | -|DLBCL |Yes |No |1.249 |3.642 | |
|
| 35 | -|FL |Yes |No |7.439 |0.000 | |
|
| 31 | +[[include:dnds_BCR.md]] |
|
| 36 | 32 | |
| 37 | 33 | ## aSHM regions |
| 38 | 34 |
BIRC3.md
| ... | ... | @@ -27,11 +27,7 @@ link-citations: true |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |Yes |No |0.000 |0 | |
|
| 33 | -|DLBCL |Yes |No |1.404 |0 | |
|
| 34 | -|FL |Yes |No |2.427 |0 | |
|
| 30 | +[[include:dnds_BIRC3.md]] |
|
| 35 | 31 | |
| 36 | 32 | ## aSHM regions |
| 37 | 33 |
BRD4.md
| ... | ... | @@ -28,11 +28,7 @@ Due to [minimal support](BRD4#representative-mutation) in the original primary d |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |No |No |0.342 |0 | |
|
| 34 | -|DLBCL |No |No |0.000 |0 | |
|
| 35 | -|FL |No |No |0.000 |0 | |
|
| 31 | +[[include:dnds_BRD4.md]] |
|
| 36 | 32 | |
| 37 | 33 | |
| 38 | 34 |
BRINP3.md
| ... | ... | @@ -28,11 +28,7 @@ Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.<sup |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |No |No |4.218 |0.00 | |
|
| 34 | -|DLBCL |No |No |1.138 |0.00 | |
|
| 35 | -|FL |No |No |1.586 |6.33 | |
|
| 31 | +[[include:dnds_BRINP3.md]] |
|
| 36 | 32 | |
| 37 | 33 | |
| 38 | 34 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/BRINP3_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/BRINP3_protein_hg38.html) |
BTBD3.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL in 2013[@zhangGeneticHetero |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |5.604 |0 | |
|
| 31 | -|DLBCL |No |No |0.722 |0 | |
|
| 32 | -|FL |No |No |2.655 |0 | |
|
| 28 | +[[include:dnds_BTBD3.md]] |
|
| 33 | 29 | |
| 34 | 30 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/BTBD3_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/BTBD3_protein_hg38.html) |
| 35 | 31 |
CAD.md
| ... | ... | @@ -28,11 +28,7 @@ Due to [minimal support](CAD#representative-mutation) in the original primary da |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |No |No |0.965 |0 | |
|
| 34 | -|DLBCL |No |No |1.949 |0 | |
|
| 35 | -|FL |No |No |0.000 |0 | |
|
| 31 | +[[include:dnds_CAD.md]] |
|
| 36 | 32 | |
| 37 | 33 | |
| 38 | 34 |
CADPS2.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL in 2021 by Hübschmann et a |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |0.311 |2.676 | |
|
| 31 | -|DLBCL |No |No |1.217 |1.199 | |
|
| 32 | -|FL |No |No |0.921 |0.000 | |
|
| 28 | +[[include:dnds_CADPS2.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/CADPS2_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/CADPS2_protein_hg38.html) |
CASP8.md
| ... | ... | @@ -28,11 +28,7 @@ Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.<sup |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |No |No |12.972 |0 | |
|
| 34 | -|DLBCL |No |No | 6.371 |0 | |
|
| 35 | -|FL |No |No | 8.788 |0 | |
|
| 31 | +[[include:dnds_CASP8.md]] |
|
| 36 | 32 | |
| 37 | 33 | |
| 38 | 34 |
CBLB.md
| ... | ... | @@ -28,11 +28,7 @@ Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.<sup |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |No |No |0.956 |0 | |
|
| 34 | -|DLBCL |No |No |2.519 |0 | |
|
| 35 | -|FL |No |No |0.000 |0 | |
|
| 31 | +[[include:dnds_CBLB.md]] |
|
| 36 | 32 | |
| 37 | 33 | |
| 38 | 34 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/CBLB_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/CBLB_protein_hg38.html) |
CCL4.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |0.000 |0 | |
|
| 30 | -|DLBCL |No |No |3.891 |0 | |
|
| 31 | -|FL |No |No |0.000 |0 | |
|
| 27 | +[[include:dnds_CCL4.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
CCNF.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |2.194 |0 | |
|
| 28 | -|DLBCL |No |No |1.303 |0 | |
|
| 29 | -|FL |No |No |0.000 |0 | |
|
| 25 | +[[include:dnds_CCNF.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/CCNF_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/CCNF_protein_hg38.html) |
CCT6B.md
| ... | ... | @@ -29,11 +29,7 @@ Due to [minimal support](CCT6B#representative-mutations) in the original primary |
| 29 | 29 | |
| 30 | 30 | ## Mutation pattern and selective pressure estimates |
| 31 | 31 | |
| 32 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 33 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 34 | -|BL |No |No |1.893 |0 | |
|
| 35 | -|DLBCL |No |No |0.000 |0 | |
|
| 36 | -|FL |No |No |0.000 |0 | |
|
| 32 | +[[include:dnds_CCT6B.md]] |
|
| 37 | 33 | |
| 38 | 34 | |
| 39 | 35 |
CD22.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.<sup |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |4.287 |0 | |
|
| 31 | -|DLBCL |No |No |1.951 |0 | |
|
| 32 | -|FL |No |No |0.000 |0 | |
|
| 28 | +[[include:dnds_CD22.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/CD22_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/CD22_protein_hg38.html) |
CD274.md
| ... | ... | @@ -27,11 +27,7 @@ Although rare, mutations have the potential to impact PD-L1 expression and could |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |No |No |5.538 | 0.000 | |
|
| 33 | -|DLBCL |No |No |2.633 |49.045 | |
|
| 34 | -|FL |No |No |4.631 |42.709 | |
|
| 30 | +[[include:dnds_CD274.md]] |
|
| 35 | 31 | |
| 36 | 32 | |
| 37 | 33 |
CD36.md
| ... | ... | @@ -25,11 +25,7 @@ CD36 is a transmembrane glycoprotein involved in fatty acid metabolism, glucose |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |4.616 |0.000 | |
|
| 31 | -|DLBCL |No |No |0.822 |7.247 | |
|
| 32 | -|FL |No |No |1.559 |0.000 | |
|
| 28 | +[[include:dnds_CD36.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
CD44.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |Yes |No |0.00 |0 | |
|
| 30 | -|DLBCL |Yes |No |2.09 |0 | |
|
| 31 | -|FL |Yes |No |0.00 |0 | |
|
| 27 | +[[include:dnds_CD44.md]] |
|
| 32 | 28 | |
| 33 | 29 | ## aSHM regions |
| 34 | 30 |
CD74.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |Yes |No | 0.000 | 0.000 | |
|
| 29 | -|DLBCL |Yes |No | 7.870 |13.428 | |
|
| 30 | -|FL |Yes |No |15.844 |34.375 | |
|
| 26 | +[[include:dnds_CD74.md]] |
|
| 31 | 27 | |
| 32 | 28 | ## aSHM regions |
| 33 | 29 |
CD79A.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |0.000 | 0.000 | |
|
| 30 | -|DLBCL |No |No |1.810 |16.146 | |
|
| 31 | -|FL |No |No |3.676 |33.801 | |
|
| 27 | +[[include:dnds_CD79A.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
CDC73.md
| ... | ... | @@ -31,11 +31,7 @@ Mutations in this gene were first described in BL in 2012 by Love et al<sup>1</s |
| 31 | 31 | |
| 32 | 32 | ## Mutation pattern and selective pressure estimates |
| 33 | 33 | |
| 34 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 35 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 36 | -|BL |No |No |3.951 |0 | |
|
| 37 | -|DLBCL |No |No |1.702 |0 | |
|
| 38 | -|FL |No |No |3.603 |0 | |
|
| 34 | +[[include:dnds_CDC73.md]] |
|
| 39 | 35 | |
| 40 | 36 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/CDC73_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/CDC73_protein_hg38.html) |
| 41 | 37 |
CDH17.md
| ... | ... | @@ -28,11 +28,7 @@ Due to [minimal support](CDH17#representative-mutations) in the original primary |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |No |No |0.000 |0.000 | |
|
| 34 | -|DLBCL |No |No |0.635 |6.343 | |
|
| 35 | -|FL |No |No |0.000 |0.000 | |
|
| 31 | +[[include:dnds_CDH17.md]] |
|
| 36 | 32 | |
| 37 | 33 | |
| 38 | 34 |
CDH8.md
| ... | ... | @@ -21,11 +21,7 @@ link-citations: true |
| 21 | 21 | |
| 22 | 22 | ## Mutation pattern and selective pressure estimates |
| 23 | 23 | |
| 24 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 25 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 26 | -|BL |No |No |2.176 |0.00 | |
|
| 27 | -|DLBCL |No |No |0.926 |3.68 | |
|
| 28 | -|FL |No |No |0.000 |0.00 | |
|
| 24 | +[[include:dnds_CDH8.md]] |
|
| 29 | 25 | |
| 30 | 26 | |
| 31 | 27 |
CDH9.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |0.920 |0 | |
|
| 30 | -|DLBCL |No |No |2.641 |0 | |
|
| 31 | -|FL |No |No |0.774 |0 | |
|
| 27 | +[[include:dnds_CDH9.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
CDKN2C.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |16.525 |50.872 | |
|
| 28 | -|DLBCL |No |No | 3.474 | 0.000 | |
|
| 29 | -|FL |No |No | 0.000 | 0.000 | |
|
| 25 | +[[include:dnds_CDKN2C.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
CHD1.md
| ... | ... | @@ -27,11 +27,7 @@ Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.<sup |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |No |No |0.674 |2.751 | |
|
| 33 | -|DLBCL |No |No |1.993 |4.965 | |
|
| 34 | -|FL |No |No |0.000 |0.000 | |
|
| 30 | +[[include:dnds_CHD1.md]] |
|
| 35 | 31 | |
| 36 | 32 | |
| 37 | 33 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/CHD1_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/CHD1_protein_hg38.html) |
CHD4.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |1.781 |0 | |
|
| 28 | -|DLBCL |No |No |3.513 |0 | |
|
| 29 | -|FL |No |No |1.815 |0 | |
|
| 25 | +[[include:dnds_CHD4.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
CHST2.md
| ... | ... | @@ -27,11 +27,7 @@ Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.<sup |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |No |No |0.786 |0 | |
|
| 33 | -|DLBCL |No |No |0.000 |0 | |
|
| 34 | -|FL |No |No |0.000 |0 | |
|
| 30 | +[[include:dnds_CHST2.md]] |
|
| 35 | 31 | |
| 36 | 32 | |
| 37 | 33 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/CHST2_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/CHST2_protein_hg38.html) |
CILP.md
| ... | ... | @@ -21,11 +21,7 @@ link-citations: true |
| 21 | 21 | |
| 22 | 22 | ## Mutation pattern and selective pressure estimates |
| 23 | 23 | |
| 24 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 25 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 26 | -|BL |No |No |0.915 |0 | |
|
| 27 | -|DLBCL |No |No |0.460 |0 | |
|
| 28 | -|FL |No |No |0.000 |0 | |
|
| 24 | +[[include:dnds_CILP.md]] |
|
| 29 | 25 | |
| 30 | 26 | |
| 31 | 27 |
CNOT2.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL in 2021 by Hübschmann et a |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |1.053 | 0.000 | |
|
| 31 | -|DLBCL |No |No |5.016 |12.509 | |
|
| 32 | -|FL |No |No |0.000 |23.991 | |
|
| 28 | +[[include:dnds_CNOT2.md]] |
|
| 33 | 29 | |
| 34 | 30 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/CNOT2_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/CNOT2_protein_hg38.html) |
| 35 | 31 |
CNTNAP5.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL in 2013 by Morin et al.<sup |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |1.357 |0.000 | |
|
| 31 | -|DLBCL |No |No |1.375 |2.662 | |
|
| 32 | -|FL |No |No |2.893 |0.000 | |
|
| 28 | +[[include:dnds_CNTNAP5.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/CNTNAP5_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/CNTNAP5_protein_hg38.html) |
COL4A2.md
| ... | ... | @@ -29,11 +29,7 @@ Due to [minimal support](COL4A2#representative-mutations) in the original primar |
| 29 | 29 | |
| 30 | 30 | ## Mutation pattern and selective pressure estimates |
| 31 | 31 | |
| 32 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 33 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 34 | -|BL |No |No |0.564 |0 | |
|
| 35 | -|DLBCL |No |No |1.209 |0 | |
|
| 36 | -|FL |No |No |1.043 |0 | |
|
| 32 | +[[include:dnds_COL4A2.md]] |
|
| 37 | 33 | |
| 38 | 34 | |
| 39 | 35 |
COQ7.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |2.304 |0 | |
|
| 30 | -|DLBCL |No |No |2.025 |0 | |
|
| 31 | -|FL |No |No |0.000 |0 | |
|
| 27 | +[[include:dnds_COQ7.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
CPNE8.md
| ... | ... | @@ -22,11 +22,7 @@ Mutations in this gene were first described in FL in 2021 by Hübschmann et al.< |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.932 | 0.000 | |
|
| 28 | -|DLBCL |No |No |2.398 | 0.000 | |
|
| 29 | -|FL |No |No |1.808 |12.601 | |
|
| 25 | +[[include:dnds_CPNE8.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
CPXM2.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |1.570 |0 | |
|
| 29 | -|DLBCL |No |No |0.000 |0 | |
|
| 30 | -|FL |No |No |1.307 |0 | |
|
| 26 | +[[include:dnds_CPXM2.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
CRIP1.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |0.000 |0 | |
|
| 30 | -|DLBCL |No |No |4.617 |0 | |
|
| 31 | -|FL |No |No |0.000 |0 | |
|
| 27 | +[[include:dnds_CRIP1.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
CTCF.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |5.383 |0 | |
|
| 31 | -|DLBCL |No |No |4.542 |0 | |
|
| 32 | -|FL |No |No |0.000 |0 | |
|
| 28 | +[[include:dnds_CTCF.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
CXCR5.md
| ... | ... | @@ -28,11 +28,7 @@ CXCR5 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |Yes |No |2.351 | 0.000 | |
|
| 34 | -|DLBCL |Yes |No |1.785 | 0.000 | |
|
| 35 | -|FL |Yes |No |2.934 |76.955 | |
|
| 31 | +[[include:dnds_CXCR5.md]] |
|
| 36 | 32 | |
| 37 | 33 | ## aSHM regions |
| 38 | 34 |
CYB5D1.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |0 |0 | |
|
| 31 | -|DLBCL |No |No |0 |0 | |
|
| 32 | -|FL |No |No |0 |0 | |
|
| 28 | +[[include:dnds_CYB5D1.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
CYP2A6.md
| ... | ... | @@ -21,11 +21,7 @@ link-citations: true |
| 21 | 21 | |
| 22 | 22 | ## Mutation pattern and selective pressure estimates |
| 23 | 23 | |
| 24 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 25 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 26 | -|BL |No |No |1.079 |0 | |
|
| 27 | -|DLBCL |No |No |0.000 |0 | |
|
| 28 | -|FL |No |No |0.000 |0 | |
|
| 24 | +[[include:dnds_CYP2A6.md]] |
|
| 29 | 25 | |
| 30 | 26 | |
| 31 | 27 |
CYP4F22.md
| ... | ... | @@ -29,11 +29,7 @@ Due to [minimal support](CYP4F22#representative-mutation) in the original primar |
| 29 | 29 | |
| 30 | 30 | ## Mutation pattern and selective pressure estimates |
| 31 | 31 | |
| 32 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 33 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 34 | -|BL |No |No |1.467 |9.614 | |
|
| 35 | -|DLBCL |No |No |1.320 |0.000 | |
|
| 36 | -|FL |No |No |0.000 |0.000 | |
|
| 32 | +[[include:dnds_CYP4F22.md]] |
|
| 37 | 33 | |
| 38 | 34 | |
| 39 | 35 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/CYP4F22_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/CYP4F22_protein_hg38.html) |
DAZAP1.md
| ... | ... | @@ -28,11 +28,7 @@ This gene has some recurrent sites of mutations (hot spots). The mutation patter |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |No |No |0 | 0.000 | |
|
| 34 | -|DLBCL |No |No |0 |35.642 | |
|
| 35 | -|FL |No |No |0 |53.351 | |
|
| 31 | +[[include:dnds_DAZAP1.md]] |
|
| 36 | 32 | |
| 37 | 33 | |
| 38 | 34 | ## DAZAP1 Hotspots |
DCAF6.md
| ... | ... | @@ -27,11 +27,7 @@ Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.<sup |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |No |No |0.969 |0 | |
|
| 33 | -|DLBCL |No |No |3.355 |0 | |
|
| 34 | -|FL |No |No |0.000 |0 | |
|
| 30 | +[[include:dnds_DCAF6.md]] |
|
| 35 | 31 | |
| 36 | 32 | |
| 37 | 33 |
DDX10.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |1.927 |0.000 | |
|
| 30 | -|DLBCL |No |No |0.000 |7.884 | |
|
| 31 | -|FL |No |No |0.000 |0.000 | |
|
| 27 | +[[include:dnds_DDX10.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
DHX15.md
| ... | ... | @@ -22,11 +22,7 @@ Mutations in this gene were first described in FL in 2021 by Hübschmann et al.< |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.721 | 0.000 | |
|
| 28 | -|DLBCL |No |No |0.742 | 0.000 | |
|
| 29 | -|FL |No |No |2.763 |23.133 | |
|
| 25 | +[[include:dnds_DHX15.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
DHX16.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL in 2021 by Hübschmann et a |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |0.298 | 0.00 | |
|
| 31 | -|DLBCL |No |No |2.652 |11.87 | |
|
| 32 | -|FL |No |No |3.825 | 0.00 | |
|
| 28 | +[[include:dnds_DHX16.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
DICER1.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0.609 |0 | |
|
| 32 | -|DLBCL |No |No |0.818 |0 | |
|
| 33 | -|FL |No |No |2.448 |0 | |
|
| 29 | +[[include:dnds_DICER1.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
DLGAP1.md
| ... | ... | @@ -29,11 +29,7 @@ Due to [minimal support](DLGAP1#representative-mutation) in the original primary |
| 29 | 29 | |
| 30 | 30 | ## Mutation pattern and selective pressure estimates |
| 31 | 31 | |
| 32 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 33 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 34 | -|BL |No |No |1.501 |0 | |
|
| 35 | -|DLBCL |No |No |1.143 |0 | |
|
| 36 | -|FL |No |No |0.682 |0 | |
|
| 32 | +[[include:dnds_DLGAP1.md]] |
|
| 37 | 33 | |
| 38 | 34 | |
| 39 | 35 |
DNAH5.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |1.484 |1.096 | |
|
| 30 | -|DLBCL |No |No |1.720 |0.000 | |
|
| 31 | -|FL |No |No |1.327 |0.000 | |
|
| 27 | +[[include:dnds_DNAH5.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
DNM2.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschma |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No | 1.878 |7.821 | |
|
| 31 | -|DLBCL |No |No | 4.605 |0.000 | |
|
| 32 | -|FL |No |No |10.522 |0.000 | |
|
| 28 | +[[include:dnds_DNM2.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 | ## DNM2 Hotspots |
DNMT1.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |0.947 |0.000 | |
|
| 31 | -|DLBCL |No |No |0.000 |6.494 | |
|
| 32 | -|FL |No |No |2.053 |0.000 | |
|
| 28 | +[[include:dnds_DNMT1.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
DNMT3A.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0 |0 | |
|
| 32 | -|DLBCL |No |No |0 |0 | |
|
| 33 | -|FL |No |No |0 |0 | |
|
| 29 | +[[include:dnds_DNMT3A.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
DOCK1.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |0.528 |0 | |
|
| 30 | -|DLBCL |No |No |1.001 |0 | |
|
| 31 | -|FL |No |No |1.838 |0 | |
|
| 27 | +[[include:dnds_DOCK1.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
DSG4.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |1.456 |4.388 | |
|
| 30 | -|DLBCL |No |No |1.561 |3.392 | |
|
| 31 | -|FL |No |No |1.374 |0.000 | |
|
| 27 | +[[include:dnds_DSG4.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
E2F2.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |7.419 |25.977 | |
|
| 29 | -|DLBCL |No |No |0.000 | 0.000 | |
|
| 30 | -|FL |No |No |0.000 | 0.000 | |
|
| 26 | +[[include:dnds_E2F2.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
EDNRB.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |3.877 | 0.000 | |
|
| 29 | -|DLBCL |No |No |0.482 | 0.000 | |
|
| 30 | -|FL |No |No |2.521 |28.057 | |
|
| 26 | +[[include:dnds_EDNRB.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
EHD1.md
| ... | ... | @@ -21,11 +21,7 @@ link-citations: true |
| 21 | 21 | |
| 22 | 22 | ## Mutation pattern and selective pressure estimates |
| 23 | 23 | |
| 24 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 25 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 26 | -|BL |No |No |0.000 | 0.000 | |
|
| 27 | -|DLBCL |No |No |2.422 |16.476 | |
|
| 28 | -|FL |No |No |2.540 | 0.000 | |
|
| 24 | +[[include:dnds_EHD1.md]] |
|
| 29 | 25 | |
| 30 | 26 | |
| 31 | 27 |
EIF2AK3.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |2.775 |12.366 | |
|
| 28 | -|DLBCL |No |No |1.884 |18.647 | |
|
| 29 | -|FL |No |No |9.265 |22.931 | |
|
| 25 | +[[include:dnds_EIF2AK3.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
EIF4A1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |8.506 |0 | |
|
| 29 | -|DLBCL |No |No |2.745 |0 | |
|
| 30 | -|FL |No |No |0.000 |0 | |
|
| 26 | +[[include:dnds_EIF4A1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/EIF4A1_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/EIF4A1_protein_hg38.html) |
EML2.md
| ... | ... | @@ -27,11 +27,7 @@ Due to [minimal support](EML2#representative-mutation) in the original primary d |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |No |No |0.000 |0 | |
|
| 33 | -|DLBCL |No |No |0.000 |0 | |
|
| 34 | -|FL |No |No |3.717 |0 | |
|
| 30 | +[[include:dnds_EML2.md]] |
|
| 35 | 31 | |
| 36 | 32 | |
| 37 | 33 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/EML2_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/EML2_protein_hg38.html) |
ENTPD3.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |2.892 |16.794 | |
|
| 31 | -|DLBCL |No |No |1.331 | 0.000 | |
|
| 32 | -|FL |No |No |0.000 | 0.000 | |
|
| 28 | +[[include:dnds_ENTPD3.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
EPHB2.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0.886 |0 | |
|
| 32 | -|DLBCL |No |No |0.586 |0 | |
|
| 33 | -|FL |No |No |0.000 |0 | |
|
| 29 | +[[include:dnds_EPHB2.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
EPPK1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |1.066 |0.0 | |
|
| 29 | -|DLBCL |No |No |1.164 |7.7 | |
|
| 30 | -|FL |No |No |2.802 |0.0 | |
|
| 26 | +[[include:dnds_EPPK1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 | ## EPPK1 Hotspots |
ERAP1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |3.083 |0 | |
|
| 29 | -|DLBCL |No |No |0.000 |0 | |
|
| 30 | -|FL |No |No |0.000 |0 | |
|
| 26 | +[[include:dnds_ERAP1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
EXOSC6.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0 |0 | |
|
| 28 | -|DLBCL |No |No |0 |0 | |
|
| 29 | -|FL |No |No |0 |0 | |
|
| 25 | +[[include:dnds_EXOSC6.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
FAT4.md
| ... | ... | @@ -27,11 +27,7 @@ link-citations: true |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |No |No |0.000 |0.000 | |
|
| 33 | -|DLBCL |No |No |1.682 |4.189 | |
|
| 34 | -|FL |No |No |0.000 |0.000 | |
|
| 30 | +[[include:dnds_FAT4.md]] |
|
| 35 | 31 | |
| 36 | 32 | |
| 37 | 33 |
FBXW7.md
| ... | ... | @@ -24,11 +24,7 @@ In leukemias, FBXW7 mutations enhance the activity of leukemia-initiating cells |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |3.846 | 0.000 | |
|
| 30 | -|DLBCL |No |No |2.734 |10.734 | |
|
| 31 | -|FL |No |No |2.987 |22.593 | |
|
| 27 | +[[include:dnds_FBXW7.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
FGFR3.md
| ... | ... | @@ -28,11 +28,7 @@ Due to [minimal support](FGFR3#representative-mutation) in the original primary |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |No |No |1.974 |0 | |
|
| 34 | -|DLBCL |No |No |1.140 |0 | |
|
| 35 | -|FL |No |No |0.000 |0 | |
|
| 31 | +[[include:dnds_FGFR3.md]] |
|
| 36 | 32 | |
| 37 | 33 | |
| 38 | 34 |
FLYWCH1.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0 |13.882 | |
|
| 28 | -|DLBCL |No |No |0 | 0.000 | |
|
| 29 | -|FL |No |No |0 | 0.000 | |
|
| 25 | +[[include:dnds_FLYWCH1.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
FNDC1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |1.313 |4.152 | |
|
| 29 | -|DLBCL |No |No |0.315 |0.000 | |
|
| 30 | -|FL |No |No |0.000 |0.000 | |
|
| 26 | +[[include:dnds_FNDC1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
FOXC1.md
| ... | ... | @@ -25,11 +25,7 @@ FOXC1 is a transcription factor that regulates genes involved in cell growth, di |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |0.000 |0 | |
|
| 31 | -|DLBCL |No |No |0.824 |0 | |
|
| 32 | -|FL |No |No |1.906 |0 | |
|
| 28 | +[[include:dnds_FOXC1.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
FOXP1.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |Yes |No |1.218 | 9.469 | |
|
| 30 | -|DLBCL |Yes |No |7.387 |17.777 | |
|
| 31 | -|FL |Yes |No |0.000 | 0.000 | |
|
| 27 | +[[include:dnds_FOXP1.md]] |
|
| 32 | 28 | |
| 33 | 29 | ## aSHM regions |
| 34 | 30 |
FTCD.md
| ... | ... | @@ -31,11 +31,7 @@ Due to [minimal support](FTCD#representative-mutation) in the original primary d |
| 31 | 31 | |
| 32 | 32 | ## Mutation pattern and selective pressure estimates |
| 33 | 33 | |
| 34 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 35 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 36 | -|BL |No |No |3.359 |0 | |
|
| 37 | -|DLBCL |No |No |0.000 |0 | |
|
| 38 | -|FL |No |No |0.000 |0 | |
|
| 34 | +[[include:dnds_FTCD.md]] |
|
| 39 | 35 | |
| 40 | 36 | |
| 41 | 37 |
FUBP1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.886 | 6.918 | |
|
| 29 | -|DLBCL |No |No |0.000 | 9.093 | |
|
| 30 | -|FL |No |No |7.430 |26.002 | |
|
| 26 | +[[include:dnds_FUBP1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
FUT5.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.000 |0 | |
|
| 29 | -|DLBCL |No |No |3.328 |0 | |
|
| 30 | -|FL |No |No |0.000 |0 | |
|
| 26 | +[[include:dnds_FUT5.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
FZD3.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0.000 |0 | |
|
| 32 | -|DLBCL |No |No |0.000 |0 | |
|
| 33 | -|FL |No |No |1.522 |0 | |
|
| 29 | +[[include:dnds_FZD3.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
FZR1.md
| ... | ... | @@ -22,11 +22,7 @@ Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschma |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No | 1.365 |0 | |
|
| 28 | -|DLBCL |No |No | 4.444 |0 | |
|
| 29 | -|FL |No |No |12.412 |0 | |
|
| 25 | +[[include:dnds_FZR1.md]] |
|
| 30 | 26 | |
| 31 | 27 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/FZR1_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/FZR1_protein_hg38.html) |
| 32 | 28 |
GABRA2.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.000 |8.135 | |
|
| 29 | -|DLBCL |No |No |0.502 |0.000 | |
|
| 30 | -|FL |No |No |1.493 |0.000 | |
|
| 26 | +[[include:dnds_GABRA2.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
GAK.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL in 2021 by Hübschmann et a |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |3.849 |0.000 | |
|
| 31 | -|DLBCL |No |No |0.798 |9.151 | |
|
| 32 | -|FL |No |No |0.000 |0.000 | |
|
| 28 | +[[include:dnds_GAK.md]] |
|
| 33 | 29 | |
| 34 | 30 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/GAK_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/GAK_protein_hg38.html) |
| 35 | 31 |
GBP7.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |No |0.582 |0 | |
|
| 26 | -|DLBCL |No |No |0.000 |0 | |
|
| 27 | -|FL |No |No |0.000 |0 | |
|
| 23 | +[[include:dnds_GBP7.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 |
GNAS.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |3.064 |13.8 | |
|
| 31 | -|DLBCL |No |No |0.967 | 0.0 | |
|
| 32 | -|FL |No |No |1.581 | 0.0 | |
|
| 28 | +[[include:dnds_GNAS.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
GOLGA5.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |2.362 |0 | |
|
| 29 | -|DLBCL |No |No |0.000 |0 | |
|
| 30 | -|FL |No |No |3.693 |0 | |
|
| 26 | +[[include:dnds_GOLGA5.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
GPC5.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |1.380 |0 | |
|
| 29 | -|DLBCL |No |No |0.000 |0 | |
|
| 30 | -|FL |No |No |1.144 |0 | |
|
| 26 | +[[include:dnds_GPC5.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
GRIK5.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |1.060 |0 | |
|
| 30 | -|DLBCL |No |No |2.412 |0 | |
|
| 31 | -|FL |No |No |1.801 |0 | |
|
| 27 | +[[include:dnds_GRIK5.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
GRM6.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |No |1.95 |0 | |
|
| 26 | -|DLBCL |No |No |1.43 |0 | |
|
| 27 | -|FL |No |No |0.00 |0 | |
|
| 23 | +[[include:dnds_GRM6.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 |
GTSE1.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |2.224 |0 | |
|
| 28 | -|DLBCL |No |No |0.000 |0 | |
|
| 29 | -|FL |No |No |0.000 |0 | |
|
| 25 | +[[include:dnds_GTSE1.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
HDAC7.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |2.610 |0 | |
|
| 29 | -|DLBCL |No |No |1.696 |0 | |
|
| 30 | -|FL |No |No |6.314 |0 | |
|
| 26 | +[[include:dnds_HDAC7.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
HEPH.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |No |0.000 |0 | |
|
| 26 | -|DLBCL |No |No |0.876 |0 | |
|
| 27 | -|FL |No |No |0.000 |0 | |
|
| 23 | +[[include:dnds_HEPH.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 |
HLA-DMA.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene are relatively rare in DLBCL overall. |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |3.255 | 0.000 | |
|
| 31 | -|DLBCL |No |No |3.359 |38.853 | |
|
| 32 | -|FL |No |No |0.000 |76.864 | |
|
| 28 | +[[include:dnds_HLA-DMA.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
HLA-DQA1.md
| ... | ... | @@ -26,11 +26,7 @@ Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschma |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0 |0 | |
|
| 32 | -|DLBCL |No |No |0 |0 | |
|
| 33 | -|FL |No |No |0 |0 | |
|
| 29 | +[[include:dnds_HLA-DQA1.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
HLA-DQB1.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0 |0 | |
|
| 28 | -|DLBCL |No |No |0 |0 | |
|
| 29 | -|FL |No |No |0 |0 | |
|
| 25 | +[[include:dnds_HLA-DQB1.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
HNF1B.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.000 |0 | |
|
| 29 | -|DLBCL |No |No |0.000 |0 | |
|
| 30 | -|FL |No |No |2.652 |0 | |
|
| 26 | +[[include:dnds_HNF1B.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
HNRNPH1.md
| ... | ... | @@ -31,11 +31,7 @@ The common HNRNPH1 mutations cause deregulated splicing and increased expression |
| 31 | 31 | |
| 32 | 32 | ## Mutation pattern and selective pressure estimates |
| 33 | 33 | |
| 34 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 35 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 36 | -|BL |No |No |1.573 | 0.000 | |
|
| 37 | -|DLBCL |No |No |2.337 |10.139 | |
|
| 38 | -|FL |No |No |0.000 | 0.000 | |
|
| 34 | +[[include:dnds_HNRNPH1.md]] |
|
| 39 | 35 | |
| 40 | 36 | ## HNRNPH1 Hotspots |
| 41 | 37 |
HRAS.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0 |0 | |
|
| 32 | -|DLBCL |No |No |0 |0 | |
|
| 33 | -|FL |No |No |0 |0 | |
|
| 29 | +[[include:dnds_HRAS.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
IER2.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |2.695 |0 | |
|
| 29 | -|DLBCL |No |No |0.319 |0 | |
|
| 30 | -|FL |No |No |0.000 |0 | |
|
| 26 | +[[include:dnds_IER2.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 | ## IER2 Expression |
IFNGR1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |2.008 |0 | |
|
| 29 | -|DLBCL |No |No |0.000 |0 | |
|
| 30 | -|FL |No |No |0.000 |0 | |
|
| 26 | +[[include:dnds_IFNGR1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
IGLL5.md
| ... | ... | @@ -30,11 +30,7 @@ link-citations: true |
| 30 | 30 | |
| 31 | 31 | ## Mutation pattern and selective pressure estimates |
| 32 | 32 | |
| 33 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 34 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 35 | -|BL |Yes |Yes |7.850 |3.210 | |
|
| 36 | -|DLBCL |Yes |Yes |3.376 |5.315 | |
|
| 37 | -|FL |Yes |Yes |4.830 |9.846 | |
|
| 33 | +[[include:dnds_IGLL5.md]] |
|
| 38 | 34 | |
| 39 | 35 | ## aSHM regions |
| 40 | 36 |
IKBKB.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |4.726 |0 | |
|
| 31 | -|DLBCL |No |No |1.593 |0 | |
|
| 32 | -|FL |No |No |3.189 |0 | |
|
| 28 | +[[include:dnds_IKBKB.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
IKBKE.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschma |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |1.102 |0 | |
|
| 31 | -|DLBCL |No |No |3.279 |0 | |
|
| 32 | -|FL |No |No |0.000 |0 | |
|
| 28 | +[[include:dnds_IKBKE.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
IL16.md
| ... | ... | @@ -26,11 +26,7 @@ The IL16 gene, which encodes a pro-inflammatory cytokine, plays a role in immune |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0.941 |0 | |
|
| 32 | -|DLBCL |No |No |1.966 |0 | |
|
| 33 | -|FL |No |No |0.000 |0 | |
|
| 29 | +[[include:dnds_IL16.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
IL6.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.000 |0 | |
|
| 29 | -|DLBCL |No |No |4.532 |0 | |
|
| 30 | -|FL |No |No |0.000 |0 | |
|
| 26 | +[[include:dnds_IL6.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
INO80.md
| ... | ... | @@ -26,11 +26,7 @@ Mutations in this gene were first described in DLBCL in 2013[@zhangGeneticHetero |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |1.227 |0.000 | |
|
| 32 | -|DLBCL |No |No |2.156 |5.706 | |
|
| 33 | -|FL |No |No |0.000 |0.000 | |
|
| 29 | +[[include:dnds_INO80.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
IRF1.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschma |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |Yes |No |2.409 | 0.000 | |
|
| 31 | -|DLBCL |Yes |No |2.468 |39.294 | |
|
| 32 | -|FL |Yes |No |6.465 | 0.000 | |
|
| 28 | +[[include:dnds_IRF1.md]] |
|
| 33 | 29 | |
| 34 | 30 | ## aSHM regions |
| 35 | 31 |
ITPR3.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |0.546 |0 | |
|
| 31 | -|DLBCL |No |No |1.349 |0 | |
|
| 32 | -|FL |No |No |1.332 |0 | |
|
| 28 | +[[include:dnds_ITPR3.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
JAK1.md
| ... | ... | @@ -27,11 +27,7 @@ Mutations in this gene were first described in DLBCL in 2013[@zhangGeneticHetero |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |No |No |1.067 |0 | |
|
| 33 | -|DLBCL |No |No |4.294 |0 | |
|
| 34 | -|FL |No |No |0.000 |0 | |
|
| 30 | +[[include:dnds_JAK1.md]] |
|
| 35 | 31 | |
| 36 | 32 | |
| 37 | 33 |
JAK3.md
| ... | ... | @@ -26,11 +26,7 @@ Mutations in this gene were first described in DLBCL in 2013[@zhangGeneticHetero |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |1.034 |0 | |
|
| 32 | -|DLBCL |No |No |0.000 |0 | |
|
| 33 | -|FL |No |No |0.000 |0 | |
|
| 29 | +[[include:dnds_JAK3.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
JUP.md
| ... | ... | @@ -22,11 +22,7 @@ Mutations in this gene were first described in FL in 2021 by Hübschmann et al.< |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |1.441 |8.462 | |
|
| 28 | -|DLBCL |No |No |4.770 |0.000 | |
|
| 29 | -|FL |No |No |8.023 |0.000 | |
|
| 25 | +[[include:dnds_JUP.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/JUP_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/JUP_protein_hg38.html) |
KCMF1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.000 |0 | |
|
| 29 | -|DLBCL |No |No |0.000 |0 | |
|
| 30 | -|FL |No |No |6.003 |0 | |
|
| 26 | +[[include:dnds_KCMF1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
KCNK10.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |1.406 |0 | |
|
| 32 | -|DLBCL |No |No |0.632 |0 | |
|
| 33 | -|FL |No |No |0.000 |0 | |
|
| 29 | +[[include:dnds_KCNK10.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
KIFC3.md
| ... | ... | @@ -26,11 +26,7 @@ Due to [minimal support](KIFC3#representative-mutations) in the original primary |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |1.012 |5.98 | |
|
| 32 | -|DLBCL |No |No |0.000 |0.00 | |
|
| 33 | -|FL |No |No |2.064 |0.00 | |
|
| 29 | +[[include:dnds_KIFC3.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
KIR3DL1.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |No |0 | 0.000 | |
|
| 26 | -|DLBCL |No |No |0 |25.433 | |
|
| 27 | -|FL |No |No |0 | 0.000 | |
|
| 23 | +[[include:dnds_KIR3DL1.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 |
KLHL21.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |Yes |No |0.000 |0 | |
|
| 29 | -|DLBCL |Yes |No |1.741 |0 | |
|
| 30 | -|FL |Yes |No |0.000 |0 | |
|
| 26 | +[[include:dnds_KLHL21.md]] |
|
| 31 | 27 | |
| 32 | 28 | ## aSHM regions |
| 33 | 29 |
KLHL26.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.487 |0 | |
|
| 28 | -|DLBCL |No |No |2.471 |0 | |
|
| 29 | -|FL |No |No |0.000 |0 | |
|
| 25 | +[[include:dnds_KLHL26.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
LAMA5.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.000 |0.000 | |
|
| 29 | -|DLBCL |No |No |2.765 |4.134 | |
|
| 30 | -|FL |No |No |0.000 |0.000 | |
|
| 26 | +[[include:dnds_LAMA5.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
LAPTM5.md
| ... | ... | @@ -27,11 +27,7 @@ Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschma |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |Yes |No | 0.000 |34.096 | |
|
| 33 | -|DLBCL |Yes |No | 4.311 |46.640 | |
|
| 34 | -|FL |Yes |Yes |15.566 |93.829 | |
|
| 30 | +[[include:dnds_LAPTM5.md]] |
|
| 35 | 31 | |
| 36 | 32 | ## aSHM regions |
| 37 | 33 |
LCOR.md
| ... | ... | @@ -29,11 +29,7 @@ LCOR (Ligand Dependent Nuclear Receptor Corepressor) is involved in the regulati |
| 29 | 29 | |
| 30 | 30 | ## Mutation pattern and selective pressure estimates |
| 31 | 31 | |
| 32 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 33 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 34 | -|BL |No |No |0 |0 | |
|
| 35 | -|DLBCL |No |No |0 |0 | |
|
| 36 | -|FL |No |No |0 |0 | |
|
| 32 | +[[include:dnds_LCOR.md]] |
|
| 37 | 33 | |
| 38 | 34 | |
| 39 | 35 |
LIN54.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |0.770 | 7.752 | |
|
| 31 | -|DLBCL |No |No |1.385 |26.297 | |
|
| 32 | -|FL |No |No |0.000 | 0.000 | |
|
| 28 | +[[include:dnds_LIN54.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
LPP.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |Yes |No |0 |0 | |
|
| 30 | -|DLBCL |Yes |No |0 |0 | |
|
| 31 | -|FL |Yes |No |0 |0 | |
|
| 27 | +[[include:dnds_LPP.md]] |
|
| 32 | 28 | |
| 33 | 29 | ## aSHM regions |
| 34 | 30 |
LRP12.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL in 2021 by Hübschmann et a |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |1.217 |7.902 | |
|
| 31 | -|DLBCL |No |No |2.242 |0.000 | |
|
| 32 | -|FL |No |No |1.384 |0.000 | |
|
| 28 | +[[include:dnds_LRP12.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
LYN.md
| ... | ... | @@ -25,11 +25,7 @@ LYN mutations have been reported in DLBCL but the rate is relatively rare in mos |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No | 1.641 | 0.000 | |
|
| 31 | -|DLBCL |No |No |10.031 |17.456 | |
|
| 32 | -|FL |No |No | 0.000 | 0.000 | |
|
| 28 | +[[include:dnds_LYN.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
MAGEC1.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |Yes |26.895 |0.000 | |
|
| 26 | -|DLBCL |No |No | 1.032 |4.703 | |
|
| 27 | -|FL |No |No | 0.000 |0.000 | |
|
| 23 | +[[include:dnds_MAGEC1.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 |
MAGT1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |2.329 | 0.000 | |
|
| 29 | -|DLBCL |No |No |0.000 |57.832 | |
|
| 30 | -|FL |No |No |0.000 | 0.000 | |
|
| 26 | +[[include:dnds_MAGT1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
MAP3K6.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |1.004 |0 | |
|
| 30 | -|DLBCL |No |No |0.442 |0 | |
|
| 31 | -|FL |No |No |1.344 |0 | |
|
| 27 | +[[include:dnds_MAP3K6.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
MAP4K4.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |1.518 |0.000 | |
|
| 31 | -|DLBCL |No |No |4.689 |6.978 | |
|
| 32 | -|FL |No |No |0.000 |0.000 | |
|
| 28 | +[[include:dnds_MAP4K4.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
MAP7D1.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |No |0.000 |0 | |
|
| 26 | -|DLBCL |No |No |1.034 |0 | |
|
| 27 | -|FL |No |No |0.000 |0 | |
|
| 23 | +[[include:dnds_MAP7D1.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 |
MARK1.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0.923 |0 | |
|
| 32 | -|DLBCL |No |No |0.000 |0 | |
|
| 33 | -|FL |No |No |2.768 |0 | |
|
| 29 | +[[include:dnds_MARK1.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
MCL1.md
| ... | ... | @@ -33,11 +33,7 @@ MCL1 is one of [a number of genes](https://github.com/morinlab/LLMPP/wiki/ashm) |
| 33 | 33 | |
| 34 | 34 | ## Mutation pattern and selective pressure estimates |
| 35 | 35 | |
| 36 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 37 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 38 | -|BL |Yes |No |5.101 |0.000 | |
|
| 39 | -|DLBCL |Yes |No |0.427 |2.401 | |
|
| 40 | -|FL |Yes |No |0.000 |0.000 | |
|
| 36 | +[[include:dnds_MCL1.md]] |
|
| 41 | 37 | |
| 42 | 38 | ## aSHM regions |
| 43 | 39 |
MECOM.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |1.490 |0 | |
|
| 29 | -|DLBCL |No |No |1.131 |0 | |
|
| 30 | -|FL |No |No |0.000 |0 | |
|
| 26 | +[[include:dnds_MECOM.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
MET.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |1.327 |0 | |
|
| 29 | -|DLBCL |No |No |1.141 |0 | |
|
| 30 | -|FL |No |No |0.000 |0 | |
|
| 26 | +[[include:dnds_MET.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
MKI67.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |1.547 |0 | |
|
| 30 | -|DLBCL |No |No |1.029 |0 | |
|
| 31 | -|FL |No |No |0.987 |0 | |
|
| 27 | +[[include:dnds_MKI67.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
MME.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0.702 |0 | |
|
| 32 | -|DLBCL |No |No |1.177 |0 | |
|
| 33 | -|FL |No |No |0.000 |0 | |
|
| 29 | +[[include:dnds_MME.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
MPDZ.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |2.932 |8.789 | |
|
| 30 | -|DLBCL |No |No |0.632 |1.772 | |
|
| 31 | -|FL |No |No |2.769 |0.000 | |
|
| 27 | +[[include:dnds_MPDZ.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
MS4A1.md
| ... | ... | @@ -25,11 +25,7 @@ In relapsed DLBCLs, MS4A1 is sometimes mutated and these mutations have been sho |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |Yes |No |2.434 |29.43 | |
|
| 31 | -|DLBCL |Yes |No |0.000 | 0.00 | |
|
| 32 | -|FL |Yes |No |0.000 | 0.00 | |
|
| 28 | +[[include:dnds_MS4A1.md]] |
|
| 33 | 29 | |
| 34 | 30 | ## aSHM regions |
| 35 | 31 |
MSH2.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |0.680 |0 | |
|
| 31 | -|DLBCL |No |No |2.838 |0 | |
|
| 32 | -|FL |No |No |3.261 |0 | |
|
| 28 | +[[include:dnds_MSH2.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
MSH6.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |3.383 |0 | |
|
| 29 | -|DLBCL |No |No |3.213 |0 | |
|
| 30 | -|FL |No |No |0.000 |0 | |
|
| 26 | +[[include:dnds_MSH6.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
MYB.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |2.555 |0 | |
|
| 32 | -|DLBCL |No |No |0.000 |0 | |
|
| 33 | -|FL |No |No |2.377 |0 | |
|
| 29 | +[[include:dnds_MYB.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
MYBPC2.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |1.437 |6.011 | |
|
| 29 | -|DLBCL |No |No |0.653 |0.000 | |
|
| 30 | -|FL |No |No |4.460 |0.000 | |
|
| 26 | +[[include:dnds_MYBPC2.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
MYCBP2.md
| ... | ... | @@ -22,11 +22,7 @@ Mutations in this gene were first described in FL in 2021 by Hübschmann et al.< |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.120 |1.153 | |
|
| 28 | -|DLBCL |No |No |0.941 |0.000 | |
|
| 29 | -|FL |No |No |0.850 |7.277 | |
|
| 25 | +[[include:dnds_MYCBP2.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/MYCBP2_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/MYCBP2_protein_hg38.html) |
MYH10.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |1.026 |0 | |
|
| 30 | -|DLBCL |No |No |2.598 |0 | |
|
| 31 | -|FL |No |No |1.997 |0 | |
|
| 27 | +[[include:dnds_MYH10.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
MYO18A.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |2.248 |0 | |
|
| 28 | -|DLBCL |No |No |0.412 |0 | |
|
| 29 | -|FL |No |No |2.227 |0 | |
|
| 25 | +[[include:dnds_MYO18A.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
MYOM2.md
| ... | ... | @@ -26,11 +26,7 @@ The prevalence of MYOM2 mutations in DLBCL varies across studies. The role of th |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |2.021 | 0.000 | |
|
| 32 | -|DLBCL |No |No |0.893 | 2.648 | |
|
| 33 | -|FL |No |No |0.649 |12.057 | |
|
| 29 | +[[include:dnds_MYOM2.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
NANOG.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0 |0 | |
|
| 29 | -|DLBCL |No |No |0 |0 | |
|
| 30 | -|FL |No |No |0 |0 | |
|
| 26 | +[[include:dnds_NANOG.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
NAV1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.719 |0 | |
|
| 29 | -|DLBCL |No |No |0.532 |0 | |
|
| 30 | -|FL |No |No |1.343 |0 | |
|
| 26 | +[[include:dnds_NAV1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
NBEAL1.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |1.484 |0.000 | |
|
| 28 | -|DLBCL |No |No |0.765 |2.824 | |
|
| 29 | -|FL |No |No |0.863 |0.000 | |
|
| 25 | +[[include:dnds_NBEAL1.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
NCOR1.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |0.496 |2.331 | |
|
| 31 | -|DLBCL |No |No |0.935 |4.098 | |
|
| 32 | -|FL |No |No |1.147 |0.000 | |
|
| 28 | +[[include:dnds_NCOR1.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
NCOR2.md
| ... | ... | @@ -32,11 +32,7 @@ Mutations in this gene are relatively rare in DLBCL overall but show a pattern o |
| 32 | 32 | |
| 33 | 33 | ## Mutation pattern and selective pressure estimates |
| 34 | 34 | |
| 35 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 36 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 37 | -|BL |No |No |0.551 |0.000 | |
|
| 38 | -|DLBCL |No |No |1.376 |4.613 | |
|
| 39 | -|FL |No |No |0.985 |0.000 | |
|
| 35 | +[[include:dnds_NCOR2.md]] |
|
| 40 | 36 | |
| 41 | 37 | |
| 42 | 38 |
NF1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |1.485 |0.000 | |
|
| 29 | -|DLBCL |No |No |1.135 |2.469 | |
|
| 30 | -|FL |No |No |0.000 |0.000 | |
|
| 26 | +[[include:dnds_NF1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
NFKB2.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |1.937 |0.00 | |
|
| 32 | -|DLBCL |No |No |0.861 |8.02 | |
|
| 33 | -|FL |No |No |2.873 |0.00 | |
|
| 29 | +[[include:dnds_NFKB2.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
NLRP5.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |1.110 |2.507 | |
|
| 29 | -|DLBCL |No |No |1.256 |0.000 | |
|
| 30 | -|FL |No |No |3.057 |0.000 | |
|
| 26 | +[[include:dnds_NLRP5.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
NLRP8.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |2.456 |7.316 | |
|
| 30 | -|DLBCL |No |No |2.731 |0.000 | |
|
| 31 | -|FL |No |No |0.000 |0.000 | |
|
| 27 | +[[include:dnds_NLRP8.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/NLRP8_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/NLRP8_protein_hg38.html) |
NOA1.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.647 |0 | |
|
| 28 | -|DLBCL |No |No |0.000 |0 | |
|
| 29 | -|FL |No |No |0.000 |0 | |
|
| 25 | +[[include:dnds_NOA1.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/NOA1_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/NOA1_protein_hg38.html) |
NRXN2.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |1.039 |0 | |
|
| 30 | -|DLBCL |No |No |1.624 |0 | |
|
| 31 | -|FL |No |No |0.000 |0 | |
|
| 27 | +[[include:dnds_NRXN2.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/NRXN2_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/NRXN2_protein_hg38.html) |
OR8H2.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |No |1.795 |0 | |
|
| 26 | -|DLBCL |No |No |0.000 |0 | |
|
| 27 | -|FL |No |No |7.647 |0 | |
|
| 23 | +[[include:dnds_OR8H2.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 |
P2RX5.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |Yes |No |2.368 |12.182 | |
|
| 29 | -|DLBCL |Yes |No |4.647 |21.997 | |
|
| 30 | -|FL |Yes |No |0.000 | 0.000 | |
|
| 26 | +[[include:dnds_P2RX5.md]] |
|
| 31 | 27 | |
| 32 | 28 | ## aSHM regions |
| 33 | 29 |
P2RY2.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.862 |0 | |
|
| 28 | -|DLBCL |No |No |0.000 |0 | |
|
| 29 | -|FL |No |No |0.000 |0 | |
|
| 25 | +[[include:dnds_P2RY2.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
PABPC4L.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |2.776 |0 | |
|
| 32 | -|DLBCL |No |No |2.948 |0 | |
|
| 33 | -|FL |No |No |0.000 |0 | |
|
| 29 | +[[include:dnds_PABPC4L.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
PAPOLG.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.000 |0 | |
|
| 29 | -|DLBCL |No |No |1.554 |0 | |
|
| 30 | -|FL |No |No |4.497 |0 | |
|
| 26 | +[[include:dnds_PAPOLG.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
PASK.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |3.029 |0 | |
|
| 29 | -|DLBCL |No |No |0.681 |0 | |
|
| 30 | -|FL |No |No |1.504 |0 | |
|
| 26 | +[[include:dnds_PASK.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
PAX5.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |Yes |No | 6.750 |0 | |
|
| 29 | -|DLBCL |Yes |Yes |14.089 |0 | |
|
| 30 | -|FL |Yes |No |10.963 |0 | |
|
| 26 | +[[include:dnds_PAX5.md]] |
|
| 31 | 27 | |
| 32 | 28 | ## aSHM regions |
| 33 | 29 |
PC.md
| ... | ... | @@ -25,11 +25,7 @@ Due to [minimal support](PC#representative-mutations) in the original primary da |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |2.187 | 0.000 | |
|
| 31 | -|DLBCL |No |No |0.000 |10.914 | |
|
| 32 | -|FL |No |No |0.000 |27.654 | |
|
| 28 | +[[include:dnds_PC.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/PC_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/PC_protein_hg38.html) |
PCDHA11.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |1.171 |0 | |
|
| 32 | -|DLBCL |No |No |0.000 |0 | |
|
| 33 | -|FL |No |No |0.784 |0 | |
|
| 29 | +[[include:dnds_PCDHA11.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
PCDHB11.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |2.106 | 0.000 | |
|
| 29 | -|DLBCL |No |No |0.848 |11.264 | |
|
| 30 | -|FL |No |No |1.816 | 0.000 | |
|
| 26 | +[[include:dnds_PCDHB11.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/PCDHB11_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/PCDHB11_protein_hg38.html) |
PCLO.md
| ... | ... | @@ -27,11 +27,7 @@ link-citations: true |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |No |No |0.000 |0.000 | |
|
| 33 | -|DLBCL |No |No |1.223 |0.389 | |
|
| 34 | -|FL |No |No |0.000 |0.000 | |
|
| 30 | +[[include:dnds_PCLO.md]] |
|
| 35 | 31 | |
| 36 | 32 | |
| 37 | 33 | ## PCLO Hotspots |
PDCD11.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |4.985 |0 | |
|
| 28 | -|DLBCL |No |No |2.400 |0 | |
|
| 29 | -|FL |No |No |0.000 |0 | |
|
| 25 | +[[include:dnds_PDCD11.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
PDE4DIP.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |1.344 |1.032 | |
|
| 29 | -|DLBCL |No |No |1.467 |5.897 | |
|
| 30 | -|FL |No |No |2.010 |7.866 | |
|
| 26 | +[[include:dnds_PDE4DIP.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/PDE4DIP_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/PDE4DIP_protein_hg38.html) |
PDS5B.md
| ... | ... | @@ -27,11 +27,7 @@ link-citations: true |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |No |No |1.009 |2.705 | |
|
| 33 | -|DLBCL |No |No |1.333 |6.726 | |
|
| 34 | -|FL |No |No |0.000 |9.065 | |
|
| 30 | +[[include:dnds_PDS5B.md]] |
|
| 35 | 31 | |
| 36 | 32 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/PDS5B_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/PDS5B_protein_hg38.html) |
| 37 | 33 |
PDZRN3.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |1.623 |0 | |
|
| 32 | -|DLBCL |No |No |0.461 |0 | |
|
| 33 | -|FL |No |No |0.935 |0 | |
|
| 29 | +[[include:dnds_PDZRN3.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
PIK3CD.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |4.941 |0 | |
|
| 29 | -|DLBCL |No |No |4.970 |0 | |
|
| 30 | -|FL |No |No |5.721 |0 | |
|
| 26 | +[[include:dnds_PIK3CD.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
PIK3R1.md
| ... | ... | @@ -34,11 +34,7 @@ Mutations in this gene were first described in DLBCL in 2013[@zhangGeneticHetero |
| 34 | 34 | |
| 35 | 35 | ## Mutation pattern and selective pressure estimates |
| 36 | 36 | |
| 37 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 38 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 39 | -|BL |No |No |3.917 | 0.000 | |
|
| 40 | -|DLBCL |No |No |2.158 |16.154 | |
|
| 41 | -|FL |No |No |0.000 |14.389 | |
|
| 37 | +[[include:dnds_PIK3R1.md]] |
|
| 42 | 38 | |
| 43 | 39 | |
| 44 | 40 |
PKD1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.596 |1.458 | |
|
| 29 | -|DLBCL |No |No |0.325 |0.000 | |
|
| 30 | -|FL |No |No |1.705 |0.000 | |
|
| 26 | +[[include:dnds_PKD1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
PLCG2.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.800 | 0.000 | |
|
| 28 | -|DLBCL |No |No |2.213 |14.094 | |
|
| 29 | -|FL |No |No |1.491 | 0.000 | |
|
| 25 | +[[include:dnds_PLCG2.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
PNPO.md
| ... | ... | @@ -25,11 +25,7 @@ Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschma |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |2.503 |0 | |
|
| 31 | -|DLBCL |No |No |4.698 |0 | |
|
| 32 | -|FL |No |No |0.000 |0 | |
|
| 28 | +[[include:dnds_PNPO.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/PNPO_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/PNPO_protein_hg38.html) |
POGZ.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0 |0 | |
|
| 29 | -|DLBCL |No |No |0 |0 | |
|
| 30 | -|FL |No |No |0 |0 | |
|
| 26 | +[[include:dnds_POGZ.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
POLRMT.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |0.969 |0 | |
|
| 30 | -|DLBCL |No |No |0.000 |0 | |
|
| 31 | -|FL |No |No |0.000 |0 | |
|
| 27 | +[[include:dnds_POLRMT.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/POLRMT_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/POLRMT_protein_hg38.html) |
POR.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |2.005 |0 | |
|
| 30 | -|DLBCL |No |No |1.464 |0 | |
|
| 31 | -|FL |No |No |0.000 |0 | |
|
| 27 | +[[include:dnds_POR.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
PPP4C.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |No | 2.143 |25.647 | |
|
| 26 | -|DLBCL |No |No | 6.715 | 0.000 | |
|
| 27 | -|FL |No |No |43.394 | 0.000 | |
|
| 23 | +[[include:dnds_PPP4C.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 | ## PPP4C Hotspots |
PPP6R2.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |1.193 |0 | |
|
| 28 | -|DLBCL |No |No |0.000 |0 | |
|
| 29 | -|FL |No |No |0.000 |0 | |
|
| 25 | +[[include:dnds_PPP6R2.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
PREX1.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.633 | 4.023 | |
|
| 28 | -|DLBCL |No |No |0.722 | 4.039 | |
|
| 29 | -|FL |No |No |1.695 |10.067 | |
|
| 25 | +[[include:dnds_PREX1.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
PRKCB.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.000 |0 | |
|
| 29 | -|DLBCL |No |No |3.889 |0 | |
|
| 30 | -|FL |No |No |1.828 |0 | |
|
| 26 | +[[include:dnds_PRKCB.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
PRKDC.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0.571 |0.939 | |
|
| 32 | -|DLBCL |No |No |1.076 |0.000 | |
|
| 33 | -|FL |No |No |0.000 |7.794 | |
|
| 29 | +[[include:dnds_PRKDC.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
PRPS1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.000 |0 | |
|
| 29 | -|DLBCL |No |No |3.078 |0 | |
|
| 30 | -|FL |No |No |0.000 |0 | |
|
| 26 | +[[include:dnds_PRPS1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
PRSS22.md
| ... | ... | @@ -28,11 +28,7 @@ Due to [minimal support](PRSS22#representative-mutation) in the original primary |
| 28 | 28 | |
| 29 | 29 | ## Mutation pattern and selective pressure estimates |
| 30 | 30 | |
| 31 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 32 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 33 | -|BL |No |No |2.023 |0 | |
|
| 34 | -|DLBCL |No |No |2.370 |0 | |
|
| 35 | -|FL |No |No |0.000 |0 | |
|
| 31 | +[[include:dnds_PRSS22.md]] |
|
| 36 | 32 | |
| 37 | 33 | |
| 38 | 34 |
PTPN23.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.502 |0 | |
|
| 29 | -|DLBCL |No |No |0.736 |0 | |
|
| 30 | -|FL |No |No |0.000 |0 | |
|
| 26 | +[[include:dnds_PTPN23.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
PTPRD.md
| ... | ... | @@ -27,11 +27,7 @@ link-citations: true |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |No |No |1.905 |0.000 | |
|
| 33 | -|DLBCL |No |No |0.969 |0.000 | |
|
| 34 | -|FL |No |No |1.549 |3.769 | |
|
| 30 | +[[include:dnds_PTPRD.md]] |
|
| 35 | 31 | |
| 36 | 32 | |
| 37 | 33 |
PTPRK.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |2.146 |0.000 | |
|
| 31 | -|DLBCL |No |No |1.555 |1.797 | |
|
| 32 | -|FL |No |No |1.875 |5.021 | |
|
| 28 | +[[include:dnds_PTPRK.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
PTPRN.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |0 |0 | |
|
| 30 | -|DLBCL |No |No |0 |0 | |
|
| 31 | -|FL |No |No |0 |0 | |
|
| 27 | +[[include:dnds_PTPRN.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
PXDNL.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |1.255 |0 | |
|
| 32 | -|DLBCL |No |No |1.924 |0 | |
|
| 33 | -|FL |No |No |1.165 |0 | |
|
| 29 | +[[include:dnds_PXDNL.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
PZP.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |No |0.936 |0 | |
|
| 26 | -|DLBCL |No |No |0.273 |0 | |
|
| 27 | -|FL |No |No |1.723 |0 | |
|
| 23 | +[[include:dnds_PZP.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 |
RAC2.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |9.926 |0 | |
|
| 30 | -|DLBCL |No |No |6.256 |0 | |
|
| 31 | -|FL |No |No |0.000 |0 | |
|
| 27 | +[[include:dnds_RAC2.md]] |
|
| 32 | 28 | |
| 33 | 29 | ## RAC2 Hotspots |
| 34 | 30 |
RAD9A.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0 |0 | |
|
| 29 | -|DLBCL |No |No |0 |0 | |
|
| 30 | -|FL |No |No |0 |0 | |
|
| 26 | +[[include:dnds_RAD9A.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/RAD9A_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/RAD9A_protein_hg38.html) |
RANBP6.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |3.815 |0 | |
|
| 28 | -|DLBCL |No |No |0.306 |0 | |
|
| 29 | -|FL |No |No |0.000 |0 | |
|
| 25 | +[[include:dnds_RANBP6.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
RARA.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |0.000 |0 | |
|
| 31 | -|DLBCL |No |No |6.208 |0 | |
|
| 32 | -|FL |No |No |0.000 |0 | |
|
| 28 | +[[include:dnds_RARA.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
RBM6.md
| ... | ... | @@ -22,11 +22,7 @@ Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschma |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.85 |0 | |
|
| 28 | -|DLBCL |No |No |0.00 |0 | |
|
| 29 | -|FL |No |No |0.00 |0 | |
|
| 25 | +[[include:dnds_RBM6.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/RBM6_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/RBM6_protein_hg38.html) |
RBP3.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |0.00 |0 | |
|
| 30 | -|DLBCL |No |No |0.38 |0 | |
|
| 31 | -|FL |No |No |0.00 |0 | |
|
| 27 | +[[include:dnds_RBP3.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
RET.md
| ... | ... | @@ -26,11 +26,7 @@ Due to [minimal support](RET#representative-mutation) in the original primary da |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |1.901 |0 | |
|
| 32 | -|DLBCL |No |No |2.518 |0 | |
|
| 33 | -|FL |No |No |0.000 |0 | |
|
| 29 | +[[include:dnds_RET.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
REV3L.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |1.067 |0 | |
|
| 28 | -|DLBCL |No |No |0.915 |0 | |
|
| 29 | -|FL |No |No |0.731 |0 | |
|
| 25 | +[[include:dnds_REV3L.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
RFTN1.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |Yes |No |1.080 |0.000 | |
|
| 31 | -|DLBCL |Yes |No |3.636 |3.809 | |
|
| 32 | -|FL |Yes |No |2.622 |0.000 | |
|
| 28 | +[[include:dnds_RFTN1.md]] |
|
| 33 | 29 | |
| 34 | 30 | ## aSHM regions |
| 35 | 31 |
RHOH.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |Yes |No |0.000 |0 | |
|
| 28 | -|DLBCL |Yes |No |4.612 |0 | |
|
| 29 | -|FL |Yes |No |0.000 |0 | |
|
| 25 | +[[include:dnds_RHOH.md]] |
|
| 30 | 26 | |
| 31 | 27 | ## aSHM regions |
| 32 | 28 |
RNF144B.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |Yes |No |0 |0 | |
|
| 28 | -|DLBCL |Yes |No |0 |0 | |
|
| 29 | -|FL |Yes |No |0 |0 | |
|
| 25 | +[[include:dnds_RNF144B.md]] |
|
| 30 | 26 | |
| 31 | 27 | ## aSHM regions |
| 32 | 28 |
RPL10.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.00 |0 | |
|
| 28 | -|DLBCL |No |No |1.03 |0 | |
|
| 29 | -|FL |No |No |0.00 |0 | |
|
| 25 | +[[include:dnds_RPL10.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
RUNX1.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |0 |0 | |
|
| 31 | -|DLBCL |No |No |0 |0 | |
|
| 32 | -|FL |No |No |0 |0 | |
|
| 28 | +[[include:dnds_RUNX1.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
S1PR1.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |1.815 |0 | |
|
| 28 | -|DLBCL |No |No |2.579 |0 | |
|
| 29 | -|FL |No |No |0.000 |0 | |
|
| 25 | +[[include:dnds_S1PR1.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
SALL3.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |1.641 | 0.000 | |
|
| 32 | -|DLBCL |No |No |1.052 |13.148 | |
|
| 33 | -|FL |No |No |1.660 | 0.000 | |
|
| 29 | +[[include:dnds_SALL3.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
SAMD9L.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.289 |4.237 | |
|
| 29 | -|DLBCL |No |No |0.493 |0.000 | |
|
| 30 | -|FL |No |No |0.000 |0.000 | |
|
| 26 | +[[include:dnds_SAMD9L.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
SARM1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.000 |0 | |
|
| 29 | -|DLBCL |No |No |1.098 |0 | |
|
| 30 | -|FL |No |No |0.000 |0 | |
|
| 26 | +[[include:dnds_SARM1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
SBF1.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.613 | 0.000 | |
|
| 28 | -|DLBCL |No |No |2.003 |12.038 | |
|
| 29 | -|FL |No |No |1.554 |19.971 | |
|
| 25 | +[[include:dnds_SBF1.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
SEL1L3.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |Yes |No |0.665 |3.278 | |
|
| 28 | -|DLBCL |Yes |No |1.724 |0.000 | |
|
| 29 | -|FL |Yes |No |2.299 |0.000 | |
|
| 25 | +[[include:dnds_SEL1L3.md]] |
|
| 30 | 26 | |
| 31 | 27 | ## aSHM regions |
| 32 | 28 |
SERPINA9.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |Yes |No |4.866 | 0.000 | |
|
| 29 | -|DLBCL |Yes |No |1.343 |39.076 | |
|
| 30 | -|FL |Yes |No |5.716 |42.861 | |
|
| 26 | +[[include:dnds_SERPINA9.md]] |
|
| 31 | 27 | |
| 32 | 28 | ## aSHM regions |
| 33 | 29 |
SETD2.md
| ... | ... | @@ -26,11 +26,7 @@ Mutations in this gene were first described in DLBCL in 2013[@zhangGeneticHetero |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |2.730 |0 | |
|
| 32 | -|DLBCL |No |No |2.572 |0 | |
|
| 33 | -|FL |No |No |2.306 |0 | |
|
| 29 | +[[include:dnds_SETD2.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
SETD5.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |0.000 | 0.000 | |
|
| 30 | -|DLBCL |No |No |0.841 |32.108 | |
|
| 31 | -|FL |No |No |2.236 | 0.000 | |
|
| 27 | +[[include:dnds_SETD5.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
SHANK1.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |1.869 |0 | |
|
| 30 | -|DLBCL |No |No |0.895 |0 | |
|
| 31 | -|FL |No |No |2.138 |0 | |
|
| 27 | +[[include:dnds_SHANK1.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
SHROOM3.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |No |0.333 |0 | |
|
| 26 | -|DLBCL |No |No |1.125 |0 | |
|
| 27 | -|FL |No |No |0.774 |0 | |
|
| 23 | +[[include:dnds_SHROOM3.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 |
SIAH2.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |0.000 |0 | |
|
| 30 | -|DLBCL |No |No |9.796 |0 | |
|
| 31 | -|FL |No |No |4.227 |0 | |
|
| 27 | +[[include:dnds_SIAH2.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
SLC29A2.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |0 |0 | |
|
| 30 | -|DLBCL |No |No |0 |0 | |
|
| 31 | -|FL |No |No |0 |0 | |
|
| 27 | +[[include:dnds_SLC29A2.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
SLC34A2.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |3.011 |0 | |
|
| 29 | -|DLBCL |No |No |1.526 |0 | |
|
| 30 | -|FL |No |No |1.687 |0 | |
|
| 26 | +[[include:dnds_SLC34A2.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/SLC34A2_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/SLC34A2_protein_hg38.html) |
SNTB2.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0.000 |0 | |
|
| 32 | -|DLBCL |No |No |0.000 |0 | |
|
| 33 | -|FL |No |No |3.904 |0 | |
|
| 29 | +[[include:dnds_SNTB2.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/SNTB2_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/SNTB2_protein_hg38.html) |
SRRM2.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |1.604 |1.723 | |
|
| 31 | -|DLBCL |No |No |1.835 |0.000 | |
|
| 32 | -|FL |No |No |1.461 |0.000 | |
|
| 28 | +[[include:dnds_SRRM2.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
ST6GAL1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |Yes |No |4.123 | 0.000 | |
|
| 29 | -|DLBCL |Yes |Yes |2.511 |33.311 | |
|
| 30 | -|FL |Yes |No |0.000 | 0.000 | |
|
| 26 | +[[include:dnds_ST6GAL1.md]] |
|
| 31 | 27 | |
| 32 | 28 | ## aSHM regions |
| 33 | 29 |
STAB2.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |No |0.371 |1.052 | |
|
| 26 | -|DLBCL |No |No |0.781 |0.000 | |
|
| 27 | -|FL |No |No |1.912 |0.000 | |
|
| 23 | +[[include:dnds_STAB2.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 |
STAT5B.md
| ... | ... | @@ -27,11 +27,7 @@ Mutations in this gene were first described in DLBCL in 2013[@zhangGeneticHetero |
| 27 | 27 | |
| 28 | 28 | ## Mutation pattern and selective pressure estimates |
| 29 | 29 | |
| 30 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 31 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 32 | -|BL |No |No |1.137 |0 | |
|
| 33 | -|DLBCL |No |No |1.568 |0 | |
|
| 34 | -|FL |No |No |0.000 |0 | |
|
| 30 | +[[include:dnds_STAT5B.md]] |
|
| 35 | 31 | |
| 36 | 32 | |
| 37 | 33 |
SYK.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |2.281 | 0.00 | |
|
| 31 | -|DLBCL |No |No |3.818 |12.94 | |
|
| 32 | -|FL |No |No |0.000 | 0.00 | |
|
| 28 | +[[include:dnds_SYK.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
SYNGAP1.md
| ... | ... | @@ -26,11 +26,7 @@ Due to [minimal support](SYNGAP1#representative-mutation) in the original primar |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0.464 |0 | |
|
| 32 | -|DLBCL |No |No |0.650 |0 | |
|
| 33 | -|FL |No |No |0.000 |0 | |
|
| 29 | +[[include:dnds_SYNGAP1.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/SYNGAP1_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/SYNGAP1_protein_hg38.html) |
SYPL1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.00 | 0.000 | |
|
| 29 | -|DLBCL |No |No |2.65 |26.779 | |
|
| 30 | -|FL |No |No |0.00 | 0.000 | |
|
| 26 | +[[include:dnds_SYPL1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
TAP1.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |0.986 | 0.000 | |
|
| 30 | -|DLBCL |No |No |0.632 | 0.000 | |
|
| 31 | -|FL |No |No |3.142 |39.164 | |
|
| 27 | +[[include:dnds_TAP1.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
TBC1D4.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |Yes |No |0.792 |0.000 | |
|
| 29 | -|DLBCL |Yes |No |1.783 |6.266 | |
|
| 30 | -|FL |Yes |No |0.860 |0.000 | |
|
| 26 | +[[include:dnds_TBC1D4.md]] |
|
| 31 | 27 | |
| 32 | 28 | ## aSHM regions |
| 33 | 29 |
TBC1D9B.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |2.926 |0.000 | |
|
| 30 | -|DLBCL |No |No |0.871 |9.918 | |
|
| 31 | -|FL |No |No |0.000 |0.000 | |
|
| 27 | +[[include:dnds_TBC1D9B.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/TBC1D9B_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/TBC1D9B_protein_hg38.html) |
TGFBR2.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.941 |0.000 | |
|
| 29 | -|DLBCL |No |No |0.599 |8.085 | |
|
| 30 | -|FL |No |No |2.530 |0.000 | |
|
| 26 | +[[include:dnds_TGFBR2.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
TIGD6.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |4.838 |0 | |
|
| 30 | -|DLBCL |No |No |0.000 |0 | |
|
| 31 | -|FL |No |No |4.007 |0 | |
|
| 27 | +[[include:dnds_TIGD6.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
TIPARP.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |1.495 |0 | |
|
| 29 | -|DLBCL |No |No |0.000 |0 | |
|
| 30 | -|FL |No |No |0.000 |0 | |
|
| 26 | +[[include:dnds_TIPARP.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
TLR2.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |1.141 |0 | |
|
| 31 | -|DLBCL |No |No |3.705 |0 | |
|
| 32 | -|FL |No |No |0.000 |0 | |
|
| 28 | +[[include:dnds_TLR2.md]] |
|
| 33 | 29 | |
| 34 | 30 | ## TLR2 Hotspots |
| 35 | 31 |
TOP2A.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |3.194 |0 | |
|
| 28 | -|DLBCL |No |No |0.774 |0 | |
|
| 29 | -|FL |No |No |0.000 |0 | |
|
| 25 | +[[include:dnds_TOP2A.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
TPP1.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |No |0.831 | 0.000 | |
|
| 26 | -|DLBCL |No |No |0.969 | 0.000 | |
|
| 27 | -|FL |No |No |9.163 |29.516 | |
|
| 23 | +[[include:dnds_TPP1.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 |
TPST2.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |0.788 |0 | |
|
| 30 | -|DLBCL |No |No |2.633 |0 | |
|
| 31 | -|FL |No |No |0.000 |0 | |
|
| 27 | +[[include:dnds_TPST2.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
TRAF3.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |0.795 |0 | |
|
| 31 | -|DLBCL |No |No |1.440 |0 | |
|
| 32 | -|FL |No |No |0.000 |0 | |
|
| 28 | +[[include:dnds_TRAF3.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
TRAF6.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.000 | 0.000 | |
|
| 29 | -|DLBCL |No |No |1.970 |61.299 | |
|
| 30 | -|FL |No |No |9.831 | 0.000 | |
|
| 26 | +[[include:dnds_TRAF6.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 | ## TRAF6 Hotspots |
TRRAP.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |0.571 |0 | |
|
| 30 | -|DLBCL |No |No |1.296 |0 | |
|
| 31 | -|FL |No |No |2.757 |0 | |
|
| 27 | +[[include:dnds_TRRAP.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
TTN.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.000 |0.000 | |
|
| 28 | -|DLBCL |No |No |0.921 |1.537 | |
|
| 29 | -|FL |No |No |0.000 |0.000 | |
|
| 25 | +[[include:dnds_TTN.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 | ## TTN Hotspots |
UBE2J1.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |Yes |No | 0.000 |22.392 | |
|
| 28 | -|DLBCL |Yes |No | 0.000 |11.415 | |
|
| 29 | -|FL |Yes |No |12.947 | 0.000 | |
|
| 25 | +[[include:dnds_UBE2J1.md]] |
|
| 30 | 26 | |
| 31 | 27 | ## aSHM regions |
| 32 | 28 |
UBR5.md
| ... | ... | @@ -29,11 +29,7 @@ Mutations in this gene were first described in DLBCL in 2013[@zhangGeneticHetero |
| 29 | 29 | |
| 30 | 30 | ## Mutation pattern and selective pressure estimates |
| 31 | 31 | |
| 32 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 33 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 34 | -|BL |No |No |0.678 |1.875 | |
|
| 35 | -|DLBCL |No |No |1.342 |5.285 | |
|
| 36 | -|FL |No |No |0.918 |6.988 | |
|
| 32 | +[[include:dnds_UBR5.md]] |
|
| 37 | 33 | |
| 38 | 34 | |
| 39 | 35 |
UNC5B.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.517 |0 | |
|
| 29 | -|DLBCL |No |No |2.632 |0 | |
|
| 30 | -|FL |No |No |4.218 |0 | |
|
| 26 | +[[include:dnds_UNC5B.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/UNC5B_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/UNC5B_protein_hg38.html) |
UNC5C.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |3.406 |0 | |
|
| 30 | -|DLBCL |No |No |1.948 |0 | |
|
| 31 | -|FL |No |No |1.266 |0 | |
|
| 27 | +[[include:dnds_UNC5C.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
UNC5D.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.954 |5.751 | |
|
| 28 | -|DLBCL |No |No |1.655 |2.419 | |
|
| 29 | -|FL |No |No |1.545 |0.000 | |
|
| 25 | +[[include:dnds_UNC5D.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
VWA7.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |1.954 |0 | |
|
| 28 | -|DLBCL |No |No |1.059 |0 | |
|
| 29 | -|FL |No |No |1.950 |0 | |
|
| 25 | +[[include:dnds_VWA7.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
WAC.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0.957 |0 | |
|
| 32 | -|DLBCL |No |No |1.590 |0 | |
|
| 33 | -|FL |No |No |0.000 |0 | |
|
| 29 | +[[include:dnds_WAC.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
WDFY3.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |2.696 |0.000 | |
|
| 29 | -|DLBCL |No |No |1.207 |3.494 | |
|
| 30 | -|FL |No |No |2.069 |0.000 | |
|
| 26 | +[[include:dnds_WDFY3.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
WDR7.md
| ... | ... | @@ -26,11 +26,7 @@ link-citations: true |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0.257 |0.000 | |
|
| 32 | -|DLBCL |No |No |0.454 |0.000 | |
|
| 33 | -|FL |No |No |1.904 |8.746 | |
|
| 29 | +[[include:dnds_WDR7.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
WDR90.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |1.227 |0 | |
|
| 28 | -|DLBCL |No |No |1.118 |0 | |
|
| 29 | -|FL |No |No |0.000 |0 | |
|
| 25 | +[[include:dnds_WDR90.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
WHAMM.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.909 | 0.000 | |
|
| 28 | -|DLBCL |No |No |0.000 |12.559 | |
|
| 29 | -|FL |No |No |0.000 | 0.000 | |
|
| 25 | +[[include:dnds_WHAMM.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
WNK2.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.309 |0 | |
|
| 28 | -|DLBCL |No |No |0.637 |0 | |
|
| 29 | -|FL |No |No |0.000 |0 | |
|
| 25 | +[[include:dnds_WNK2.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
XIRP2.md
| ... | ... | @@ -20,11 +20,7 @@ link-citations: true |
| 20 | 20 | |
| 21 | 21 | ## Mutation pattern and selective pressure estimates |
| 22 | 22 | |
| 23 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 24 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 25 | -|BL |No |No |0.000 |0.000 | |
|
| 26 | -|DLBCL |No |No |2.268 |2.044 | |
|
| 27 | -|FL |No |No |0.000 |0.000 | |
|
| 23 | +[[include:dnds_XIRP2.md]] |
|
| 28 | 24 | |
| 29 | 25 | |
| 30 | 26 |
YY1.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |6.553 | 0.000 | |
|
| 29 | -|DLBCL |No |No |3.473 |57.733 | |
|
| 30 | -|FL |No |No |3.554 |61.850 | |
|
| 26 | +[[include:dnds_YY1.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
YY1AP1.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |1.988 |14.209 | |
|
| 28 | -|DLBCL |No |No |0.000 | 0.000 | |
|
| 29 | -|FL |No |No |0.000 | 0.000 | |
|
| 25 | +[[include:dnds_YY1AP1.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |
ZBTB7A.md
| ... | ... | @@ -30,11 +30,7 @@ link-citations: true |
| 30 | 30 | |
| 31 | 31 | ## Mutation pattern and selective pressure estimates |
| 32 | 32 | |
| 33 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 34 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 35 | -|BL |No |No |4.693 |0 | |
|
| 36 | -|DLBCL |No |No |1.625 |0 | |
|
| 37 | -|FL |No |No |0.000 |0 | |
|
| 33 | +[[include:dnds_ZBTB7A.md]] |
|
| 38 | 34 | |
| 39 | 35 | |
| 40 | 36 |
ZCCHC7.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |Yes |No |2.124 |0 | |
|
| 29 | -|DLBCL |Yes |No |1.558 |0 | |
|
| 30 | -|FL |Yes |No |0.000 |0 | |
|
| 26 | +[[include:dnds_ZCCHC7.md]] |
|
| 31 | 27 | |
| 32 | 28 | ## aSHM regions |
| 33 | 29 |
ZEB2.md
| ... | ... | @@ -26,11 +26,7 @@ Mutations in this gene were first described in DLBCL in 2013[@zhangGeneticHetero |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0.000 | 0.000 | |
|
| 32 | -|DLBCL |No |Yes |1.406 |33.261 | |
|
| 33 | -|FL |No |No |2.638 | 0.000 | |
|
| 29 | +[[include:dnds_ZEB2.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
ZFAT.md
| ... | ... | @@ -25,11 +25,7 @@ link-citations: true |
| 25 | 25 | |
| 26 | 26 | ## Mutation pattern and selective pressure estimates |
| 27 | 27 | |
| 28 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 29 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 30 | -|BL |No |No |0.000 |0 | |
|
| 31 | -|DLBCL |No |No |1.873 |0 | |
|
| 32 | -|FL |No |No |0.000 |0 | |
|
| 28 | +[[include:dnds_ZFAT.md]] |
|
| 33 | 29 | |
| 34 | 30 | |
| 35 | 31 |
ZFX.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |3.677 |0 | |
|
| 29 | -|DLBCL |No |No |0.000 |0 | |
|
| 30 | -|FL |No |No |0.000 |0 | |
|
| 26 | +[[include:dnds_ZFX.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
ZNF217.md
| ... | ... | @@ -24,11 +24,7 @@ link-citations: true |
| 24 | 24 | |
| 25 | 25 | ## Mutation pattern and selective pressure estimates |
| 26 | 26 | |
| 27 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 28 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 29 | -|BL |No |No |1.310 |0 | |
|
| 30 | -|DLBCL |No |No |2.456 |0 | |
|
| 31 | -|FL |No |No |0.000 |0 | |
|
| 27 | +[[include:dnds_ZNF217.md]] |
|
| 32 | 28 | |
| 33 | 29 | |
| 34 | 30 |
ZNF229.md
| ... | ... | @@ -26,11 +26,7 @@ Due to [minimal support](ZNF229#representative-mutation) in the original primary |
| 26 | 26 | |
| 27 | 27 | ## Mutation pattern and selective pressure estimates |
| 28 | 28 | |
| 29 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 30 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 31 | -|BL |No |No |0.954 |0 | |
|
| 32 | -|DLBCL |No |No |1.346 |0 | |
|
| 33 | -|FL |No |No |0.000 |0 | |
|
| 29 | +[[include:dnds_ZNF229.md]] |
|
| 34 | 30 | |
| 35 | 31 | |
| 36 | 32 |
ZNF423.md
| ... | ... | @@ -23,11 +23,7 @@ link-citations: true |
| 23 | 23 | |
| 24 | 24 | ## Mutation pattern and selective pressure estimates |
| 25 | 25 | |
| 26 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 27 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 28 | -|BL |No |No |0.594 |0 | |
|
| 29 | -|DLBCL |No |No |1.430 |0 | |
|
| 30 | -|FL |No |No |0.836 |0 | |
|
| 26 | +[[include:dnds_ZNF423.md]] |
|
| 31 | 27 | |
| 32 | 28 | |
| 33 | 29 |
ZNF85.md
| ... | ... | @@ -22,11 +22,7 @@ link-citations: true |
| 22 | 22 | |
| 23 | 23 | ## Mutation pattern and selective pressure estimates |
| 24 | 24 | |
| 25 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 26 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 27 | -|BL |No |No |0.000 |0 | |
|
| 28 | -|DLBCL |No |No |1.446 |0 | |
|
| 29 | -|FL |No |No |0.000 |0 | |
|
| 25 | +[[include:dnds_ZNF85.md]] |
|
| 30 | 26 | |
| 31 | 27 | |
| 32 | 28 |