d0c449ae43ce116f5e76180f0140869858333fbe
GRB2.md
| ... | ... | @@ -12,7 +12,6 @@ Further research is needed to elucidate its specific role in DLBCL. |
| 12 | 12 | timeline |
| 13 | 13 | title Publication timing |
| 14 | 14 | 2011-07-31 : Pasqualucci : DLBCL |
| 15 | - 2019-09-26 : Panea : BL |
|
| 16 | 15 | ``` |
| 17 | 16 | |
| 18 | 17 | ## Relevance tier by entity |
| ... | ... | @@ -20,7 +19,6 @@ timeline |
| 20 | 19 | |Entity|Tier|Description | |
| 21 | 20 | |:------:|:----:|--------------------------------------| |
| 22 | 21 | | |1 |high-confidence DLBCL gene | |
| 23 | -| |2 |relevance in BL seems unlikely| |
|
| 24 | 22 | |
| 25 | 23 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 26 | 24 | |
| ... | ... | @@ -30,9 +28,6 @@ timeline |
| 30 | 28 | |DLBCL |Schmitz cohort |2.77 | |
| 31 | 29 | |DLBCL |Reddy cohort |1.50 | |
| 32 | 30 | |DLBCL |Chapuy cohort |2.99 | |
| 33 | -|BL |GAMBL genomes+capture|0.46 | |
|
| 34 | -|BL |Thomas cohort |0.40 | |
|
| 35 | -|BL |Panea cohort |1.00 | |
|
| 36 | 31 | |
| 37 | 32 | ## Mutation pattern and selective pressure estimates |
| 38 | 33 | |
| ... | ... | @@ -40,8 +35,6 @@ timeline |
| 40 | 35 | |:------:|:----:|:---------------------:|:----------------:|:----------------:| |
| 41 | 36 | |DLBCL |No |Yes |33.029 |168.982 | |
| 42 | 37 | |FL |No |No | 8.575 | 0.000 | |
| 43 | -|BL |No |No | 7.253 | 0.000 | |
|
| 44 | - |
|
| 45 | 38 | |
| 46 | 39 | |
| 47 | 40 | |
| ... | ... | @@ -61,4 +54,3 @@ View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/G |
| 61 | 54 | |
| 62 | 55 | ## References |
| 63 | 56 | 1. Pasqualucci L, Trifonov V, Fabbri G, Ma J, Rossi D, Chiarenza A, Wells VA, Grunn A, Messina M, Elliot O, Chan J, Bhagat G, Chadburn A, Gaidano G, Mullighan CG, Rabadan R, Dalla-Favera R. Analysis of the coding genome of diffuse large B-cell lymphoma. Nat Genet. 2011 Jul 31;43(9):830–837. PMCID: PMC3297422 |
| 64 | -2. Panea R, Love C, Shingleton JR, Reddy A, Bailey J, Moormann A, Otieno J, Ong’echa J, Oduor C, Schroêder K, Masalu N, Chao N, Agajanian M, Major M, Fedoriw Y, Richards K, Rymkiewicz G, Miles R, Alobeid B, Bhagat G, Flowers C, Ondrejka S, Hsi E, Choi W, Au-Yeung R, Hartmann W, Lenz G, Meyerson H, Lin YY, Zhuang Y, Luftig M, Waldrop A, Dave T, Thakkar D, Sahay H, Li G, Palus B, Seshadri V, Kim S, Gascoyne R, Levy S, Mukhopadhyay M, Dunson D, Dave S. The whole genome landscape of Burkitt lymphoma subtypes. Blood. 2019; |
papers/paneaWholeGenomeLandscape2019.md
| ... | ... | @@ -52,7 +52,6 @@ All other BL studies, BL Tier 2, 111 |
| 52 | 52 | |[DTX1](../DTX1)|2 | ★ ☆ ☆ ☆ ☆| |
| 53 | 53 | |[ETS1](../ETS1)|2 | ★ ☆ ☆ ☆ ☆| |
| 54 | 54 | |[FZD3](../FZD3)|2 | ★ ☆ ☆ ☆ ☆| |
| 55 | -|[GRB2](../GRB2)|2 | ☆ ☆ ☆ ☆ ☆| |
|
| 56 | 55 | |[HIST1H1C](../HIST1H1C)|2 | ☆ ☆ ☆ ☆ ☆| |
| 57 | 56 | |[HIST1H2AG](../HIST1H2AG)|2 | ☆ ☆ ☆ ☆ ☆| |
| 58 | 57 | |[HIST1H2AM](../HIST1H2AM)|2 | ☆ ☆ ☆ ☆ ☆| |
papers/paneaWholeGenomeLandscape2019.pdf
papers/paneaWholeGenomeLandscape2019_tmp.html
| ... | ... | @@ -486,11 +486,6 @@ All other BL studies, BL Tier 2, 111 |
| 486 | 486 | <td style="text-align:center">★ ☆ ☆ ☆ ☆</td> |
| 487 | 487 | </tr> |
| 488 | 488 | <tr> |
| 489 | -<td style="text-align:left"><a href="../GRB2">GRB2</a></td> |
|
| 490 | -<td style="text-align:center">2</td> |
|
| 491 | -<td style="text-align:center">☆ ☆ ☆ ☆ ☆</td> |
|
| 492 | -</tr> |
|
| 493 | -<tr> |
|
| 494 | 489 | <td style="text-align:left"><a href="../HIST1H1C">HIST1H1C</a></td> |
| 495 | 490 | <td style="text-align:center">2</td> |
| 496 | 491 | <td style="text-align:center">☆ ☆ ☆ ☆ ☆</td> |