d88c2fedbd589c236f479c2699481d6ee5986537
ACTG1.md
| ... | ... | @@ -36,11 +36,7 @@ timeline |
| 36 | 36 | |
| 37 | 37 | ## Mutation pattern and selective pressure estimates |
| 38 | 38 | |
| 39 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 40 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 41 | -|BL |Yes |No |2.063 |8.011 | |
|
| 42 | -|DLBCL |Yes |No |2.125 |0.000 | |
|
| 43 | -|FL |Yes |No |8.128 |0.000 | |
|
| 39 | +[[include:dnds_ACTG1.md]] |
|
| 44 | 40 | |
| 45 | 41 | ## aSHM regions |
| 46 | 42 |
ATM.md
| ... | ... | @@ -33,11 +33,7 @@ Mutations in this gene were first described in MZL by Braggio et al,<sup>1</sup> |
| 33 | 33 | |
| 34 | 34 | ## Mutation pattern and selective pressure estimates |
| 35 | 35 | |
| 36 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 37 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 38 | -|BL |No |No |2.461 |0.000 | |
|
| 39 | -|DLBCL |No |No |3.529 |5.446 | |
|
| 40 | -|FL |No |No |1.679 |6.201 | |
|
| 36 | +[[include:dnds_ATM.md]] |
|
| 41 | 37 | |
| 42 | 38 | |
| 43 | 39 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/ATM_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/ATM_protein_hg38.html) |
B2M.md
| ... | ... | @@ -49,12 +49,7 @@ timeline |
| 49 | 49 | |
| 50 | 50 | ## Mutation pattern and selective pressure estimates |
| 51 | 51 | |
| 52 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 53 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 54 | -|BL |No |No | 9.379 | 56.571 | |
|
| 55 | -|DLBCL |No |Yes |60.843 |340.788 | |
|
| 56 | -|FL |No |Yes |54.190 |326.834 | |
|
| 57 | - |
|
| 52 | +[[include:dnds_B2M.md]] |
|
| 58 | 53 | |
| 59 | 54 | ## B2M Hotspots |
| 60 | 55 |
BCL10.md
| ... | ... | @@ -48,12 +48,7 @@ timeline |
| 48 | 48 | |
| 49 | 49 | ## Mutation pattern and selective pressure estimates |
| 50 | 50 | |
| 51 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 52 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 53 | -|BL |No |No | 3.224 | 0.000 | |
|
| 54 | -|DLBCL |No |Yes |13.754 |106.692 | |
|
| 55 | -|FL |No |Yes | 0.000 |223.832 | |
|
| 56 | - |
|
| 51 | +[[include:dnds_BCL10.md]] |
|
| 57 | 52 | |
| 58 | 53 | ## BCL10 Hotspots |
| 59 | 54 |
BCL2.md
| ... | ... | @@ -40,11 +40,7 @@ timeline |
| 40 | 40 | |
| 41 | 41 | ## Mutation pattern and selective pressure estimates |
| 42 | 42 | |
| 43 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 44 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 45 | -|BL |Yes |No |0.000 |0 | |
|
| 46 | -|DLBCL |Yes |Yes |2.645 |0 | |
|
| 47 | -|FL |Yes |No |1.197 |0 | |
|
| 43 | +[[include:dnds_BCL2.md]] |
|
| 48 | 44 | |
| 49 | 45 | ## aSHM regions |
| 50 | 46 |
BCL6.md
| ... | ... | @@ -40,7 +40,7 @@ timeline |
| 40 | 40 | |
| 41 | 41 | ## Mutation pattern and selective pressure estimates |
| 42 | 42 | |
| 43 | -[[include:dnds_BACH2.md]] |
|
| 43 | +[[include:dnds_BCL6.md]] |
|
| 44 | 44 | |
| 45 | 45 | ## aSHM regions |
| 46 | 46 |
BIRC6.md
| ... | ... | @@ -34,11 +34,7 @@ timeline |
| 34 | 34 | |
| 35 | 35 | ## Mutation pattern and selective pressure estimates |
| 36 | 36 | |
| 37 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 38 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 39 | -|BL |No |No |0.862 |1.339 | |
|
| 40 | -|DLBCL |No |No |1.795 |5.011 | |
|
| 41 | -|FL |No |No |2.997 |7.132 | |
|
| 37 | +[[include:dnds_BIRC6.md]] |
|
| 42 | 38 | |
| 43 | 39 | ## BIRC6 Hotspots |
| 44 | 40 |
BRAF.md
| ... | ... | @@ -36,13 +36,7 @@ timeline |
| 36 | 36 | |
| 37 | 37 | ## Mutation pattern and selective pressure estimates |
| 38 | 38 | |
| 39 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 40 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 41 | -|BL |No |No |4.754 |0 | |
|
| 42 | -|DLBCL |No |No |5.565 |0 | |
|
| 43 | -|FL |No |No |4.680 |0 | |
|
| 44 | - |
|
| 45 | - |
|
| 39 | +[[include:dnds_BRAF.md]] |
|
| 46 | 40 | |
| 47 | 41 | |
| 48 | 42 | ## BRAF Hotspots |
BTG1.md
| ... | ... | @@ -48,11 +48,7 @@ timeline |
| 48 | 48 | |
| 49 | 49 | ## Mutation pattern and selective pressure estimates |
| 50 | 50 | |
| 51 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 52 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 53 | -|BL |Yes |No |0.000 |0.000 | |
|
| 54 | -|DLBCL |Yes |No |0.498 |1.085 | |
|
| 55 | -|FL |Yes |No |4.407 |6.147 | |
|
| 51 | +[[include:dnds_BTG1.md]] |
|
| 56 | 52 | |
| 57 | 53 | ## aSHM regions |
| 58 | 54 |
BTG2.md
| ... | ... | @@ -39,11 +39,7 @@ timeline |
| 39 | 39 | |
| 40 | 40 | ## Mutation pattern and selective pressure estimates |
| 41 | 41 | |
| 42 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 43 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 44 | -|BL |Yes |No |6.152 |42.280 | |
|
| 45 | -|DLBCL |Yes |Yes |3.562 |10.265 | |
|
| 46 | -|FL |Yes |No |6.073 | 0.000 | |
|
| 42 | +[[include:dnds_BTG2.md]] |
|
| 47 | 43 | |
| 48 | 44 | ## aSHM regions |
| 49 | 45 |
BTK.md
| ... | ... | @@ -30,13 +30,7 @@ timeline |
| 30 | 30 | |
| 31 | 31 | ## Mutation pattern and selective pressure estimates |
| 32 | 32 | |
| 33 | -|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)| |
|
| 34 | -|:------:|:----:|:---------------------:|:----------------:|:----------------:| |
|
| 35 | -|BL |No |No | 0.964 | 8.202 | |
|
| 36 | -|DLBCL |No |Yes |18.082 |28.027 | |
|
| 37 | -|FL |No |Yes |39.808 |35.548 | |
|
| 38 | - |
|
| 39 | - |
|
| 33 | +[[include:dnds_BTK.md]] |
|
| 40 | 34 | |
| 41 | 35 | View coding variants in ProteinPaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/BTK_protein.html) or [hg38](https://morinlab.github.io/LLMPP/GAMBL/BTK_protein_hg38.html) |
| 42 | 36 |