Changes in d8cef14: updates

				ABI3BP.md
			
          @@ -0,0 +1,36 @@

          +# [ABI3BP]

          +

          +## Mutation tier

          +

          +|Entity|Tier|Description                              |

          +|:------:|:----:|-----------------------------------------|

          +|DLBCL |2   |relevance in DLBCL not firmly established|

          +## Mutation incidence

          +

          +|Entity|source        |frequency (%)|

          +|:------:|:--------------:|:-------------:|

          +|DLBCL |GAMBL genomes |3.44         |

          +|DLBCL |Schmitz cohort|2.34         |

          +|DLBCL |Reddy cohort  |1.80         |

          +|DLBCL |Chapuy cohort |2.99         |

          +

          +## Mutation pattern

          +

          +|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)|

          +|:------:|:----:|:---------------------:|:----------------:|:----------------:|

          +|BL    |No  |No                   |2.366           |2.365           |

          +|DLBCL |No  |No                   |1.625           |0.000           |

          +|FL    |No  |No                   |2.009           |0.000           |

          +

          +

          +> [!NOTE]

          +> First described in DLBCL in 2013 by [Morin RD](https://pubmed.ncbi.nlm.nih.gov/23699601)

          +

          +

          +View coding variants in ProteinPaint [hg19](https://www.bcgsc.ca/downloads/morinlab/GAMBL/test/genes/ABI3BP_protein.html)  or [hg38](https://www.bcgsc.ca/downloads/morinlab/GAMBL/test/genes/ABI3BP_protein_hg38.html)

          +

          +![image](images/proteinpaint/ABI3BP_NM_015429.svg)

          +

          +View all variants in GenomePaint [hg19](https://www.bcgsc.ca/downloads/morinlab/GAMBL/test/genes/ABI3BP.html)  or [hg38](https://www.bcgsc.ca/downloads/morinlab/GAMBL/test/genes/ABI3BP_hg38.html)

          +

          +![image](images/proteinpaint/ABI3BP.svg)

				ADAMTS1.md
			
          @@ -10,9 +10,9 @@

           |Entity|source        |frequency (%)|

           |:------:|:--------------:|:-------------:|

           |DLBCL |GAMBL genomes |1.91         |

          -|DLBCL |Schmitz cohort|  NA         |

          -|DLBCL |Reddy cohort  |  NA         |

          -|DLBCL |Chapuy cohort |  NA         |

          +|DLBCL |Schmitz cohort|3.40         |

          +|DLBCL |Reddy cohort  |1.70         |

          +|DLBCL |Chapuy cohort |2.56         |

           ## Mutation pattern

          @@ -24,6 +24,9 @@

           > [!NOTE]

          +> First described in DLBCL in 2021 by [Hübschmann D](https://pubmed.ncbi.nlm.nih.gov/33953289)

          +

          +

           View coding variants in ProteinPaint [hg19](https://www.bcgsc.ca/downloads/morinlab/GAMBL/test/genes/ADAMTS1_protein.html)  or [hg38](https://www.bcgsc.ca/downloads/morinlab/GAMBL/test/genes/ADAMTS1_protein_hg38.html)

           ![image](images/proteinpaint/ADAMTS1_NM_006988.svg)

...	...	@@ -0,0 +1,36 @@
	1	+# [ABI3BP]
	2	+
	3	+## Mutation tier
	4	+
	5	+\|Entity\|Tier\|Description \|
	6	+\|:------:\|:----:\|-----------------------------------------\|
	7	+\|DLBCL \|2 \|relevance in DLBCL not firmly established\|
	8	+## Mutation incidence
	9	+
	10	+\|Entity\|source \|frequency (%)\|
	11	+\|:------:\|:--------------:\|:-------------:\|
	12	+\|DLBCL \|GAMBL genomes \|3.44 \|
	13	+\|DLBCL \|Schmitz cohort\|2.34 \|
	14	+\|DLBCL \|Reddy cohort \|1.80 \|
	15	+\|DLBCL \|Chapuy cohort \|2.99 \|
	16	+
	17	+## Mutation pattern
	18	+
	19	+\|Entity\|aSHM\|Significant selection\|dN/dS (missense)\|dN/dS (nonsense)\|
	20	+\|:------:\|:----:\|:---------------------:\|:----------------:\|:----------------:\|
	21	+\|BL \|No \|No \|2.366 \|2.365 \|
	22	+\|DLBCL \|No \|No \|1.625 \|0.000 \|
	23	+\|FL \|No \|No \|2.009 \|0.000 \|
	24	+
	25	+
	26	+> [!NOTE]
	27	+> First described in DLBCL in 2013 by [Morin RD](https://pubmed.ncbi.nlm.nih.gov/23699601)
	28	+
	29	+
	30	+View coding variants in ProteinPaint [hg19](https://www.bcgsc.ca/downloads/morinlab/GAMBL/test/genes/ABI3BP_protein.html) or [hg38](https://www.bcgsc.ca/downloads/morinlab/GAMBL/test/genes/ABI3BP_protein_hg38.html)
	31	+
	32	+![image](images/proteinpaint/ABI3BP_NM_015429.svg)
	33	+
	34	+View all variants in GenomePaint [hg19](https://www.bcgsc.ca/downloads/morinlab/GAMBL/test/genes/ABI3BP.html) or [hg38](https://www.bcgsc.ca/downloads/morinlab/GAMBL/test/genes/ABI3BP_hg38.html)
	35	+
	36	+![image](images/proteinpaint/ABI3BP.svg)

...	...	@@ -10,9 +10,9 @@
10	10	\|Entity\|source \|frequency (%)\|
11	11	\|:------:\|:--------------:\|:-------------:\|
12	12	\|DLBCL \|GAMBL genomes \|1.91 \|
13		-\|DLBCL \|Schmitz cohort\| NA \|
14		-\|DLBCL \|Reddy cohort \| NA \|
15		-\|DLBCL \|Chapuy cohort \| NA \|
	13	+\|DLBCL \|Schmitz cohort\|3.40 \|
	14	+\|DLBCL \|Reddy cohort \|1.70 \|
	15	+\|DLBCL \|Chapuy cohort \|2.56 \|
16	16
17	17	## Mutation pattern
18	18
...	...	@@ -24,6 +24,9 @@
24	24
25	25
26	26	> [!NOTE]
	27	+> First described in DLBCL in 2021 by [Hübschmann D](https://pubmed.ncbi.nlm.nih.gov/33953289)
	28	+
	29	+
27	30	View coding variants in ProteinPaint [hg19](https://www.bcgsc.ca/downloads/morinlab/GAMBL/test/genes/ADAMTS1_protein.html) or [hg38](https://www.bcgsc.ca/downloads/morinlab/GAMBL/test/genes/ADAMTS1_protein_hg38.html)
28	31
29	32	![image](images/proteinpaint/ADAMTS1_NM_006988.svg)