ddf458ad12dc55696030b08c12cab5455ca20d40
BL_genes.md
| ... | ... | @@ -15,197 +15,194 @@ link-citations: true |
| 15 | 15 | |
| 16 | 16 | |Gene|Tier| First BL evidence | Other entities | |
| 17 | 17 | |:-:|:-:|:-|:-| |
| 18 | -|[ARID1A](ARID1A)|1|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@wienandGenomicAnalysesFlowsorted2019b; @krysiakRecurrentSomaticMutations2017b; @zhangGeneticHeterogeneityDiffuse2013; @rossiCodingGenomeSplenic2012c]| |
|
| 19 | -|[BCL7A](BCL7A)|1, aSHM|[Study Page](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@krysiakRecurrentSomaticMutations2017b; @reichelFlowSortingExome2015a; @arthurGenomewideDiscoverySomatic2018]| |
|
| 20 | -|[BMP7](BMP7)|1|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 21 | -|[CCND3](CCND3)|1|[Study Page](papers/richterRecurrentMutationID32012a)[@richterRecurrentMutationID32012a]|[@deschGenotypingCirculatingTumor2020; @morinFrequentMutationHistonemodifying2011; @jalladesExomeSequencingIdentifies2017]| |
|
| 22 | -|[CHD8](CHD8)|1|[Study Page](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 23 | -|[DDX3X](DDX3X)|1|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|[@schmitzGeneticsPathogenesisDiffuse2018a; @mottokIntegrativeGenomicAnalysis2019b]| |
|
| 24 | -|[EIF4A1](EIF4A1)|1|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 25 | -|[EPPK1](EPPK1)|1|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 26 | -|[FBXO11](FBXO11)|1|[Study Page](papers/richterRecurrentMutationID32012a)[@richterRecurrentMutationID32012a]|[@parryWholeExomeSequencing2013; @hubschmannMutationalMechanismsShaping2021b]| |
|
| 27 | -|[FOXO1](FOXO1)|1|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|[@dunsCharacterizationDLBCLPMBL2021b; @morinFrequentMutationHistonemodifying2011]| |
|
| 28 | -|[GNA13](GNA13)|1|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@morinFrequentMutationHistonemodifying2011; @reichelFlowSortingExome2015a]| |
|
| 29 | -|[GNAI2](GNAI2)|1|[Study Page](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@morinMutationalStructuralAnalysis2013]| |
|
| 30 | -|[HNRNPU](HNRNPU)|1, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 31 | -|[ID3](ID3)|1|[Study Page](papers/richterRecurrentMutationID32012a)[@richterRecurrentMutationID32012a]|[@schmitzBurkittLymphomaPathogenesis2012; @spinaGeneticsNodalMarginal2016b]| |
|
| 32 | -|[KMT2D](KMT2D)|1|[Study Page](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@morinFrequentMutationHistonemodifying2011; @deschGenotypingCirculatingTumor2020; @beaLandscapeSomaticMutations2013; @rossiCodingGenomeSplenic2012c]| |
|
| 33 | -|[MYC](MYC)|1, aSHM|[Study Page](papers/johnstonCmycHypermutationBurkitt1992)[@johnstonCmycHypermutationBurkitt1992]|[@pasqualucciHypermutationMultipleProtooncogenes2001a; @jalladesExomeSequencingIdentifies2017; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 34 | -|[P2RY8](P2RY8)|1|[Study Page](papers/muppidiLossSignalingGa132014b)[@muppidiLossSignalingGa132014b]|[@lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 35 | -|[PHF6](PHF6)|1|[Study Page](papers/thomasGeneticSubgroupsInform2023)[@thomasGeneticSubgroupsInform2023]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 36 | -|[PTEN](PTEN)|1|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 37 | -|[RFX7](RFX7)|1|[Study Page](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|| |
|
| 38 | -|[RHOA](RHOA)|1|[Study Page](papers/richterRecurrentMutationID32012a)[@richterRecurrentMutationID32012a]|| |
|
| 39 | -|[SIN3A](SIN3A)|1|[Study Page](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@rossiCodingGenomeSplenic2012c]| |
|
| 40 | -|[SMARCA4](SMARCA4)|1|[Study Page](papers/richterRecurrentMutationID32012a)[@richterRecurrentMutationID32012a]|[@lohrDiscoveryPrioritizationSomatic2012a; @krysiakRecurrentSomaticMutations2017b; @nadeuGenomicEpigenomicInsights2020b]| |
|
| 41 | -|[TCF3](TCF3)|1|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 42 | -|[TCL1A](TCL1A)|1, aSHM|[Study Page](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|| |
|
| 43 | -|[TFAP4](TFAP4)|1|[Study Page](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|| |
|
| 44 | -|[TP53](TP53)|1|[Study Page](papers/wildaInactivationARFMDM2p53Pathway2004)[@wildaInactivationARFMDM2p53Pathway2004]|[@lohrDiscoveryPrioritizationSomatic2012a; @morinFrequentMutationHistonemodifying2011; @beaLandscapeSomaticMutations2013; @tiacciPervasiveMutationsJAKSTAT2018b; @rossiCodingGenomeSplenic2012c]| |
|
| 45 | -|[USP7](USP7)|1|[Study Page](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|| |
|
| 46 | -|[WNK1](WNK1)|1|[Study Page](papers/thomasGeneticSubgroupsInform2023)[@thomasGeneticSubgroupsInform2023]|[@jalladesExomeSequencingIdentifies2017; @hubschmannMutationalMechanismsShaping2021b]| |
|
| 18 | +|[ARID1A](ARID1A)|1|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@zhangGeneticHeterogeneityDiffuse2013; @rossiCodingGenomeSplenic2012c; @wienandGenomicAnalysesFlowsorted2019b; @krysiakRecurrentSomaticMutations2017b]| |
|
| 19 | +|[BCL7A](BCL7A)|1, aSHM|[Study Overview](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@krysiakRecurrentSomaticMutations2017b; @arthurGenomewideDiscoverySomatic2018; @reichelFlowSortingExome2015a]| |
|
| 20 | +|[BMP7](BMP7)|1|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 21 | +|[CCND3](CCND3)|1|[Study Overview](papers/richterRecurrentMutationID32012a)[@richterRecurrentMutationID32012a]|[@morinFrequentMutationHistonemodifying2011; @deschGenotypingCirculatingTumor2020; @jalladesExomeSequencingIdentifies2017]| |
|
| 22 | +|[CHD8](CHD8)|1|[Study Overview](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 23 | +|[DDX3X](DDX3X)|1|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|[@schmitzGeneticsPathogenesisDiffuse2018a; @mottokIntegrativeGenomicAnalysis2019b]| |
|
| 24 | +|[EIF4A1](EIF4A1)|1|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 25 | +|[EPPK1](EPPK1)|1|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 26 | +|[FBXO11](FBXO11)|1|[Study Overview](papers/richterRecurrentMutationID32012a)[@richterRecurrentMutationID32012a]|[@parryWholeExomeSequencing2013; @hubschmannMutationalMechanismsShaping2021b]| |
|
| 27 | +|[FOXO1](FOXO1)|1|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|[@morinFrequentMutationHistonemodifying2011; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 28 | +|[GNA13](GNA13)|1|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@reichelFlowSortingExome2015a; @morinFrequentMutationHistonemodifying2011]| |
|
| 29 | +|[GNAI2](GNAI2)|1|[Study Overview](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@morinMutationalStructuralAnalysis2013]| |
|
| 30 | +|[HNRNPU](HNRNPU)|1, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 31 | +|[ID3](ID3)|1|[Study Overview](papers/richterRecurrentMutationID32012a)[@richterRecurrentMutationID32012a]|[@schmitzBurkittLymphomaPathogenesis2012; @spinaGeneticsNodalMarginal2016b]| |
|
| 32 | +|[KMT2D](KMT2D)|1|[Study Overview](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@deschGenotypingCirculatingTumor2020; @morinFrequentMutationHistonemodifying2011; @rossiCodingGenomeSplenic2012c; @beaLandscapeSomaticMutations2013]| |
|
| 33 | +|[MYC](MYC)|1, aSHM|[Study Overview](papers/johnstonCmycHypermutationBurkitt1992)[@johnstonCmycHypermutationBurkitt1992]|[@jalladesExomeSequencingIdentifies2017; @dunsCharacterizationDLBCLPMBL2021b; @pasqualucciHypermutationMultipleProtooncogenes2001a]| |
|
| 34 | +|[P2RY8](P2RY8)|1|[Study Overview](papers/muppidiLossSignalingGa132014b)[@muppidiLossSignalingGa132014b]|[@lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 35 | +|[PHF6](PHF6)|1|[Study Overview](papers/thomasGeneticSubgroupsInform2023)[@thomasGeneticSubgroupsInform2023]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 36 | +|[PTEN](PTEN)|1|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 37 | +|[RFX7](RFX7)|1|[Study Overview](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|| |
|
| 38 | +|[RHOA](RHOA)|1|[Study Overview](papers/richterRecurrentMutationID32012a)[@richterRecurrentMutationID32012a]|| |
|
| 39 | +|[SIN3A](SIN3A)|1|[Study Overview](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@rossiCodingGenomeSplenic2012c]| |
|
| 40 | +|[SMARCA4](SMARCA4)|1|[Study Overview](papers/richterRecurrentMutationID32012a)[@richterRecurrentMutationID32012a]|[@lohrDiscoveryPrioritizationSomatic2012a; @nadeuGenomicEpigenomicInsights2020b; @krysiakRecurrentSomaticMutations2017b]| |
|
| 41 | +|[TCF3](TCF3)|1|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 42 | +|[TCL1A](TCL1A)|1, aSHM|[Study Overview](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|| |
|
| 43 | +|[TFAP4](TFAP4)|1|[Study Overview](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|| |
|
| 44 | +|[TP53](TP53)|1|[Study Overview](papers/wildaInactivationARFMDM2p53Pathway2004)[@wildaInactivationARFMDM2p53Pathway2004]|[@lohrDiscoveryPrioritizationSomatic2012a; @beaLandscapeSomaticMutations2013; @tiacciPervasiveMutationsJAKSTAT2018b; @morinFrequentMutationHistonemodifying2011; @rossiCodingGenomeSplenic2012c]| |
|
| 45 | +|[USP7](USP7)|1|[Study Overview](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|| |
|
| 46 | +|[WNK1](WNK1)|1|[Study Overview](papers/thomasGeneticSubgroupsInform2023)[@thomasGeneticSubgroupsInform2023]|[@jalladesExomeSequencingIdentifies2017; @hubschmannMutationalMechanismsShaping2021b]| |
|
| 47 | 47 | |
| 48 | 48 | ## Tier 2 BL genes |
| 49 | 49 | |
| 50 | -### *155 total* |
|
| 50 | +### *152 total* |
|
| 51 | 51 | |
| 52 | 52 | |Gene|Tier| First BL evidence | Other entities | |
| 53 | 53 | |:-:|:-:|:-|:-| |
| 54 | -|[ACAD9](ACAD9)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 55 | -|[ACE](ACE)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 56 | -|[ADAMTS5](ADAMTS5)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 57 | -|[ADNP](ADNP)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 58 | -|[AGO4](AGO4)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 59 | -|[ALPK2](ALPK2)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 60 | -|[ARHGEF1](ARHGEF1)|2|[Study Page](papers/muppidiLossSignalingGa132014b)[@muppidiLossSignalingGa132014b]|| |
|
| 61 | -|[ATP2C2](ATP2C2)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 62 | -|[BACH2](BACH2)|2, aSHM|[Study Page](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|| |
|
| 63 | -|[BCL2](BCL2)|2, aSHM|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|[@morinFrequentMutationHistonemodifying2011; @sarkozyMutationalLandscapeGray2021a; @tanakaFrequentIncidenceSomatic1992]| |
|
| 64 | -|[BCL6](BCL6)|2, aSHM|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 65 | -|[BRAF](BRAF)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@tiacciBRAFMutationsHairycell2011a]| |
|
| 66 | -|[BRD4](BRD4)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 67 | -|[BTG1](BTG1)|2, aSHM|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|[@morinFrequentMutationHistonemodifying2011; @sarkozyMutationalLandscapeGray2021a]| |
|
| 68 | -|[BTG2](BTG2)|2, aSHM|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 69 | -|[C16orf48](C16orf48)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 70 | -|[C6orf27](C6orf27)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 71 | -|[CAD](CAD)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 72 | -|[CARD11](CARD11)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@lenzOncogenicCARD11Mutations2008; @morinFrequentMutationHistonemodifying2011; @yanBCRTLRSignaling2012a; @wuGeneticHeterogeneityPrimary2016]| |
|
| 73 | -|[CARD4](CARD4)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 74 | -|[CCNF](CCNF)|2|[Study Page](papers/abateDistinctViralMutational2015a)[@abateDistinctViralMutational2015a]|| |
|
| 75 | -|[CCT6B](CCT6B)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 76 | -|[CD79A](CD79A)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|[@rossiCodingGenomeSplenic2012c]| |
|
| 77 | -|[CD79B](CD79B)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 78 | -|[CD83](CD83)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@dunsCharacterizationDLBCLPMBL2021b; @morinMutationalStructuralAnalysis2013; @russler-germainMutationsAssociatedProgression2023b]| |
|
| 79 | -|[CDC73](CDC73)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 80 | -|[CDH17](CDH17)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 81 | -|[CDKN2A](CDKN2A)|2|[Study Page](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@morinMutationalStructuralAnalysis2013; @spinaGeneticsNodalMarginal2016b]| |
|
| 82 | -|[CDKN2C](CDKN2C)|2|[Study Page](papers/thomasGeneticSubgroupsInform2023)[@thomasGeneticSubgroupsInform2023]|| |
|
| 83 | -|[CHD4](CHD4)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 84 | -|[COL4A2](COL4A2)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 85 | -|[CPXM2](CPXM2)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 86 | -|[CREBBP](CREBBP)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@dunsCharacterizationDLBCLPMBL2021b; @parryWholeExomeSequencing2013; @pasqualucciInactivatingMutationsAcetyltransferase2011a]| |
|
| 87 | -|[CTCF](CTCF)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 88 | -|[CXCR4](CXCR4)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@krysiakRecurrentSomaticMutations2017b; @khodabakhshiRecurrentTargetsAberrant2012]| |
|
| 89 | -|[CYB5D1](CYB5D1)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 90 | -|[CYP4F22](CYP4F22)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 91 | -|[DHCR7](DHCR7)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 92 | -|[DLGAP1](DLGAP1)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 93 | -|[DNMT1](DNMT1)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 94 | -|[DTX1](DTX1)|2, aSHM|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@rossiCodingGenomeSplenic2012c; @schmitzGeneticsPathogenesisDiffuse2018a; @gomezUltraDeepSequencingReveals2023]| |
|
| 95 | -|[E2F2](E2F2)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 96 | -|[EBF1](EBF1)|2, aSHM|[Study Page](papers/thomasGeneticSubgroupsInform2023)[@thomasGeneticSubgroupsInform2023]|[@bohleRoleEarlyBcell2013; @reichelFlowSortingExome2015a]| |
|
| 97 | -|[EDNRB](EDNRB)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 98 | -|[EHD1](EHD1)|2|[Study Page](papers/thomasGeneticSubgroupsInform2023)[@thomasGeneticSubgroupsInform2023]|| |
|
| 99 | -|[EIF2C4](EIF2C4)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 100 | -|[ELP2](ELP2)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 101 | -|[EML2](EML2)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 102 | -|[ENTPD3](ENTPD3)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 103 | -|[EP300](EP300)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@rossiCodingGenomeSplenic2012c; @pasqualucciInactivatingMutationsAcetyltransferase2011a]| |
|
| 104 | -|[EPHB2](EPHB2)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 105 | -|[ERAP1](ERAP1)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 106 | -|[ETS1](ETS1)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 107 | -|[EXOSC6](EXOSC6)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 108 | -|[EZH2](EZH2)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@mottokIntegrativeGenomicAnalysis2019b; @morinSomaticMutationsAltering2010a]| |
|
| 109 | -|[FAM129B](FAM129B)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 110 | -|[FGFR3](FGFR3)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 111 | -|[FLYWCH1](FLYWCH1)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 112 | -|[FTCD](FTCD)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 113 | -|[FZD3](FZD3)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 114 | -|[GGTLA4](GGTLA4)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 115 | -|[GRB2](GRB2)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@pasqualucciAnalysisCodingGenome2011]| |
|
| 116 | -|[GRIK5](GRIK5)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 117 | -|[GTSE1](GTSE1)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 118 | -|[HIST1H1C](HIST1H1C)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 119 | -|[HIST1H1E](HIST1H1E)|2, aSHM|[Study Page](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@lohrDiscoveryPrioritizationSomatic2012a; @reichelFlowSortingExome2015a; @krysiakRecurrentSomaticMutations2017b]| |
|
| 120 | -|[HIST1H2AG](HIST1H2AG)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@morinMutationalStructuralAnalysis2013; @rossiCodingGenomeSplenic2012c; @krysiakRecurrentSomaticMutations2017b]| |
|
| 121 | -|[HIST1H2AM](HIST1H2AM)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@krysiakRecurrentSomaticMutations2017b]| |
|
| 122 | -|[HIST1H2BK](HIST1H2BK)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@rossiCodingGenomeSplenic2012c]| |
|
| 123 | -|[HIST1H3D](HIST1H3D)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 124 | -|[HIST1H3H](HIST1H3H)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 125 | -|[HIST1H3I](HIST1H3I)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@krysiakRecurrentSomaticMutations2017b]| |
|
| 126 | -|[HIST1H3J](HIST1H3J)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 127 | -|[HIST1H4J](HIST1H4J)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@mottokIntegrativeGenomicAnalysis2019b]| |
|
| 128 | -|[HLA-A](HLA-A)|2||[@lohrDiscoveryPrioritizationSomatic2012a; @deschGenotypingCirculatingTumor2020]| |
|
| 129 | -|[HLA-B](HLA-B)|2||[@wienandGenomicAnalysesFlowsorted2019b; @lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 130 | -|[HLA-DMB](HLA-DMB)|2||| |
|
| 131 | -|[HLA-DQB1](HLA-DQB1)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 132 | -|[ICK](ICK)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 133 | -|[IGLL5](IGLL5)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@deschGenotypingCirculatingTumor2020; @russler-germainMutationsAssociatedProgression2023b]| |
|
| 134 | -|[IKZF3](IKZF3)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@morinMutationalStructuralAnalysis2013]| |
|
| 135 | -|[IRF8](IRF8)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@mottokIntegrativeGenomicAnalysis2019b; @morinFrequentMutationHistonemodifying2011]| |
|
| 136 | -|[ITPR3](ITPR3)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@tiacciPervasiveMutationsJAKSTAT2018b]| |
|
| 137 | -|[KANK2](KANK2)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 138 | -|[KCNK10](KCNK10)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 139 | -|[KIFC3](KIFC3)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 140 | -|[KLHL26](KLHL26)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 141 | -|[KLHL6](KLHL6)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@morinFrequentMutationHistonemodifying2011; @ganapathiGeneticLandscapeDural2016]| |
|
| 142 | -|[KMT2C](KMT2C)|2|[Study Page](papers/zhouSporadicEndemicBurkitt2019)[@zhouSporadicEndemicBurkitt2019]|[@sarkozyMutationalLandscapeGray2021a; @zhangGeneticHeterogeneityDiffuse2013; @zhangGenomicLandscapeMantle2014]| |
|
| 143 | -|[LTB](LTB)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@deschGenotypingCirculatingTumor2020; @chapuyMolecularSubtypesDiffuse2018b]| |
|
| 144 | -|[MAP3K6](MAP3K6)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 145 | -|[MCL1](MCL1)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@dunsCharacterizationDLBCLPMBL2021b; @reddyGeneticFunctionalDrivers2017]| |
|
| 146 | -|[MIR142](MIR142)|2, aSHM|[Study Page](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@kwanhianMicroRNA142Mutated202012b]| |
|
| 147 | -|[MKI67](MKI67)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|[@russler-germainMutationsAssociatedProgression2023b]| |
|
| 148 | -|[MME](MME)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 149 | -|[MTOR](MTOR)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@zhangGeneticHeterogeneityDiffuse2013]| |
|
| 150 | -|[MYH10](MYH10)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 151 | -|[MYO18A](MYO18A)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 152 | -|[NBEAL1](NBEAL1)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 153 | -|[NCOR2](NCOR2)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|[@sarkozyMutationalLandscapeGray2021a; @spinaGeneticsNodalMarginal2016b]| |
|
| 154 | -|[NOA1](NOA1)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 155 | -|[NOTCH1](NOTCH1)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@pasqualucciAnalysisCodingGenome2011; @beaLandscapeSomaticMutations2013; @rossiCodingGenomeSplenic2012c]| |
|
| 156 | -|[NOTCH2](NOTCH2)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@troenNOTCH2MutationsMarginal2008; @beaLandscapeSomaticMutations2013; @rossiCodingGenomeSplenic2012c]| |
|
| 157 | -|[NRXN2](NRXN2)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 158 | -|[P2RY2](P2RY2)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 159 | -|[PABPC4L](PABPC4L)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 160 | -|[PC](PC)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 161 | -|[PCBP1](PCBP1)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 162 | -|[PCDHA11](PCDHA11)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 163 | -|[PDCD11](PDCD11)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 164 | -|[PDZRN3](PDZRN3)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 165 | -|[PIK3R1](PIK3R1)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@zhangGeneticHeterogeneityDiffuse2013]| |
|
| 166 | -|[PIM1](PIM1)|2, aSHM|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|[@pasqualucciHypermutationMultipleProtooncogenes2001a; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 167 | -|[PLCG2](PLCG2)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 168 | -|[POLRMT](POLRMT)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 169 | -|[POR](POR)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 170 | -|[PPP6R2](PPP6R2)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 171 | -|[PREX1](PREX1)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 172 | -|[PRSS22](PRSS22)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 173 | -|[PTPRN](PTPRN)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 174 | -|[PXDNL](PXDNL)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 175 | -|[RAC2](RAC2)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@hubschmannMutationalMechanismsShaping2021b]| |
|
| 176 | -|[RANBP6](RANBP6)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 177 | -|[RBP3](RBP3)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 178 | -|[RET](RET)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 179 | -|[REV3L](REV3L)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 180 | -|[RNF144B](RNF144B)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 181 | -|[RPL10](RPL10)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 182 | -|[S1PR2](S1PR2)|2, aSHM|[Study Page](papers/muppidiLossSignalingGa132014b)[@muppidiLossSignalingGa132014b]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 183 | -|[SAL3](SAL3)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 184 | -|[SALL3](SALL3)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@zhangGenomicLandscapeMantle2014]| |
|
| 185 | -|[SAPS2](SAPS2)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 186 | -|[SBF1](SBF1)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 187 | -|[SF3B1](SF3B1)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 188 | -|[SHANK1](SHANK1)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 189 | -|[SLC29A2](SLC29A2)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 190 | -|[SNTB2](SNTB2)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 191 | -|[SYNGAP1](SYNGAP1)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 192 | -|[TBC1D9B](TBC1D9B)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 193 | -|[TET2](TET2)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@albuquerqueEnhancingKnowledgeDiscovery2017a]| |
|
| 194 | -|[TIGD6](TIGD6)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 195 | -|[TOP2A](TOP2A)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 196 | -|[TPST2](TPST2)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 197 | -|[TTN](TTN)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 198 | -|[VWA7](VWA7)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 199 | -|[WDR7](WDR7)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 200 | -|[WDR90](WDR90)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 201 | -|[WHAMM](WHAMM)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 202 | -|[WNK2](WNK2)|2|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 203 | -|[YY1AP1](YY1AP1)|2|[Study Page](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 204 | -|[ZAN](ZAN)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 205 | -|[ZBTB7A](ZBTB7A)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 206 | -|[ZFP36L1](ZFP36L1)|2, aSHM|[Study Page](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@morinFrequentMutationHistonemodifying2011; @reichelFlowSortingExome2015a]| |
|
| 207 | -|[ZNF229](ZNF229)|2|[Study Page](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 208 | -|[ZNF85](ZNF85)|2|[Study Page](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 54 | +|[ACAD9](ACAD9)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 55 | +|[ACE](ACE)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 56 | +|[ADAMTS5](ADAMTS5)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 57 | +|[ADNP](ADNP)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 58 | +|[AGO4](AGO4)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 59 | +|[ALPK2](ALPK2)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 60 | +|[ARHGEF1](ARHGEF1)|2|[Study Overview](papers/muppidiLossSignalingGa132014b)[@muppidiLossSignalingGa132014b]|| |
|
| 61 | +|[ATP2C2](ATP2C2)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 62 | +|[BACH2](BACH2)|2, aSHM|[Study Overview](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|| |
|
| 63 | +|[BCL2](BCL2)|2, aSHM|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|[@sarkozyMutationalLandscapeGray2021a; @morinFrequentMutationHistonemodifying2011; @tanakaFrequentIncidenceSomatic1992]| |
|
| 64 | +|[BCL6](BCL6)|2, aSHM|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 65 | +|[BRAF](BRAF)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@tiacciBRAFMutationsHairycell2011a]| |
|
| 66 | +|[BRD4](BRD4)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 67 | +|[BTG1](BTG1)|2, aSHM|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|[@sarkozyMutationalLandscapeGray2021a; @morinFrequentMutationHistonemodifying2011]| |
|
| 68 | +|[BTG2](BTG2)|2, aSHM|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 69 | +|[C16orf48](C16orf48)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 70 | +|[C6orf27](C6orf27)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 71 | +|[CAD](CAD)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 72 | +|[CARD11](CARD11)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@lenzOncogenicCARD11Mutations2008; @morinFrequentMutationHistonemodifying2011; @wuGeneticHeterogeneityPrimary2016; @yanBCRTLRSignaling2012a]| |
|
| 73 | +|[CARD4](CARD4)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 74 | +|[CCNF](CCNF)|2|[Study Overview](papers/abateDistinctViralMutational2015a)[@abateDistinctViralMutational2015a]|| |
|
| 75 | +|[CCT6B](CCT6B)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 76 | +|[CD79A](CD79A)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|[@rossiCodingGenomeSplenic2012c]| |
|
| 77 | +|[CD79B](CD79B)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 78 | +|[CD83](CD83)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@russler-germainMutationsAssociatedProgression2023b; @morinMutationalStructuralAnalysis2013; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 79 | +|[CDC73](CDC73)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 80 | +|[CDH17](CDH17)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 81 | +|[CDKN2A](CDKN2A)|2|[Study Overview](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@morinMutationalStructuralAnalysis2013; @spinaGeneticsNodalMarginal2016b]| |
|
| 82 | +|[CDKN2C](CDKN2C)|2|[Study Overview](papers/thomasGeneticSubgroupsInform2023)[@thomasGeneticSubgroupsInform2023]|| |
|
| 83 | +|[CHD4](CHD4)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 84 | +|[COL4A2](COL4A2)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 85 | +|[CPXM2](CPXM2)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 86 | +|[CREBBP](CREBBP)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@parryWholeExomeSequencing2013; @dunsCharacterizationDLBCLPMBL2021b; @pasqualucciInactivatingMutationsAcetyltransferase2011a]| |
|
| 87 | +|[CTCF](CTCF)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 88 | +|[CXCR4](CXCR4)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@khodabakhshiRecurrentTargetsAberrant2012; @krysiakRecurrentSomaticMutations2017b]| |
|
| 89 | +|[CYB5D1](CYB5D1)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 90 | +|[CYP4F22](CYP4F22)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 91 | +|[DHCR7](DHCR7)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 92 | +|[DLGAP1](DLGAP1)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 93 | +|[DNMT1](DNMT1)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 94 | +|[DTX1](DTX1)|2, aSHM|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@rossiCodingGenomeSplenic2012c; @schmitzGeneticsPathogenesisDiffuse2018a; @gomezUltraDeepSequencingReveals2023]| |
|
| 95 | +|[E2F2](E2F2)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 96 | +|[EBF1](EBF1)|2, aSHM|[Study Overview](papers/thomasGeneticSubgroupsInform2023)[@thomasGeneticSubgroupsInform2023]|[@reichelFlowSortingExome2015a; @bohleRoleEarlyBcell2013]| |
|
| 97 | +|[EDNRB](EDNRB)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 98 | +|[EHD1](EHD1)|2|[Study Overview](papers/thomasGeneticSubgroupsInform2023)[@thomasGeneticSubgroupsInform2023]|| |
|
| 99 | +|[EIF2C4](EIF2C4)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 100 | +|[ELP2](ELP2)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 101 | +|[EML2](EML2)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 102 | +|[ENTPD3](ENTPD3)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 103 | +|[EP300](EP300)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@rossiCodingGenomeSplenic2012c; @pasqualucciInactivatingMutationsAcetyltransferase2011a]| |
|
| 104 | +|[EPHB2](EPHB2)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 105 | +|[ERAP1](ERAP1)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 106 | +|[ETS1](ETS1)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 107 | +|[EXOSC6](EXOSC6)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 108 | +|[EZH2](EZH2)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@morinSomaticMutationsAltering2010a; @mottokIntegrativeGenomicAnalysis2019b]| |
|
| 109 | +|[FAM129B](FAM129B)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 110 | +|[FGFR3](FGFR3)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 111 | +|[FLYWCH1](FLYWCH1)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 112 | +|[FTCD](FTCD)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 113 | +|[FZD3](FZD3)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 114 | +|[GGTLA4](GGTLA4)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 115 | +|[GRB2](GRB2)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@pasqualucciAnalysisCodingGenome2011]| |
|
| 116 | +|[GRIK5](GRIK5)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 117 | +|[GTSE1](GTSE1)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 118 | +|[HIST1H1C](HIST1H1C)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 119 | +|[HIST1H1E](HIST1H1E)|2, aSHM|[Study Overview](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@krysiakRecurrentSomaticMutations2017b; @reichelFlowSortingExome2015a; @lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 120 | +|[HIST1H2AG](HIST1H2AG)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@rossiCodingGenomeSplenic2012c; @morinMutationalStructuralAnalysis2013; @krysiakRecurrentSomaticMutations2017b]| |
|
| 121 | +|[HIST1H2AM](HIST1H2AM)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@krysiakRecurrentSomaticMutations2017b]| |
|
| 122 | +|[HIST1H2BK](HIST1H2BK)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@rossiCodingGenomeSplenic2012c]| |
|
| 123 | +|[HIST1H3D](HIST1H3D)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 124 | +|[HIST1H3H](HIST1H3H)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 125 | +|[HIST1H3I](HIST1H3I)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@krysiakRecurrentSomaticMutations2017b]| |
|
| 126 | +|[HIST1H3J](HIST1H3J)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 127 | +|[HIST1H4J](HIST1H4J)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@mottokIntegrativeGenomicAnalysis2019b]| |
|
| 128 | +|[HLA-DQB1](HLA-DQB1)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 129 | +|[ICK](ICK)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 130 | +|[IGLL5](IGLL5)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@deschGenotypingCirculatingTumor2020; @russler-germainMutationsAssociatedProgression2023b]| |
|
| 131 | +|[IKZF3](IKZF3)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@morinMutationalStructuralAnalysis2013]| |
|
| 132 | +|[IRF8](IRF8)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@mottokIntegrativeGenomicAnalysis2019b; @morinFrequentMutationHistonemodifying2011]| |
|
| 133 | +|[ITPR3](ITPR3)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@tiacciPervasiveMutationsJAKSTAT2018b]| |
|
| 134 | +|[KANK2](KANK2)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 135 | +|[KCNK10](KCNK10)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 136 | +|[KIFC3](KIFC3)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 137 | +|[KLHL26](KLHL26)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 138 | +|[KLHL6](KLHL6)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@ganapathiGeneticLandscapeDural2016; @morinFrequentMutationHistonemodifying2011]| |
|
| 139 | +|[KMT2C](KMT2C)|2|[Study Overview](papers/zhouSporadicEndemicBurkitt2019)[@zhouSporadicEndemicBurkitt2019]|[@sarkozyMutationalLandscapeGray2021a; @zhangGeneticHeterogeneityDiffuse2013; @zhangGenomicLandscapeMantle2014]| |
|
| 140 | +|[LTB](LTB)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@chapuyMolecularSubtypesDiffuse2018b; @deschGenotypingCirculatingTumor2020]| |
|
| 141 | +|[MAP3K6](MAP3K6)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 142 | +|[MCL1](MCL1)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@dunsCharacterizationDLBCLPMBL2021b; @reddyGeneticFunctionalDrivers2017]| |
|
| 143 | +|[MIR142](MIR142)|2, aSHM|[Study Overview](papers/grandeGenomewideDiscoverySomatic2019)[@grandeGenomewideDiscoverySomatic2019]|[@kwanhianMicroRNA142Mutated202012b]| |
|
| 144 | +|[MKI67](MKI67)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|[@russler-germainMutationsAssociatedProgression2023b]| |
|
| 145 | +|[MME](MME)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 146 | +|[MTOR](MTOR)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@zhangGeneticHeterogeneityDiffuse2013]| |
|
| 147 | +|[MYH10](MYH10)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 148 | +|[MYO18A](MYO18A)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 149 | +|[NBEAL1](NBEAL1)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 150 | +|[NCOR2](NCOR2)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|[@spinaGeneticsNodalMarginal2016b; @sarkozyMutationalLandscapeGray2021a]| |
|
| 151 | +|[NOA1](NOA1)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 152 | +|[NOTCH1](NOTCH1)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@pasqualucciAnalysisCodingGenome2011; @beaLandscapeSomaticMutations2013; @rossiCodingGenomeSplenic2012c]| |
|
| 153 | +|[NOTCH2](NOTCH2)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@rossiCodingGenomeSplenic2012c; @beaLandscapeSomaticMutations2013; @troenNOTCH2MutationsMarginal2008]| |
|
| 154 | +|[NRXN2](NRXN2)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 155 | +|[P2RY2](P2RY2)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 156 | +|[PABPC4L](PABPC4L)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 157 | +|[PC](PC)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 158 | +|[PCBP1](PCBP1)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 159 | +|[PCDHA11](PCDHA11)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 160 | +|[PDCD11](PDCD11)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 161 | +|[PDZRN3](PDZRN3)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 162 | +|[PIK3R1](PIK3R1)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@zhangGeneticHeterogeneityDiffuse2013]| |
|
| 163 | +|[PIM1](PIM1)|2, aSHM|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|[@dunsCharacterizationDLBCLPMBL2021b; @pasqualucciHypermutationMultipleProtooncogenes2001a]| |
|
| 164 | +|[PLCG2](PLCG2)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 165 | +|[POLRMT](POLRMT)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 166 | +|[POR](POR)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 167 | +|[PPP6R2](PPP6R2)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 168 | +|[PREX1](PREX1)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 169 | +|[PRSS22](PRSS22)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 170 | +|[PTPRN](PTPRN)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 171 | +|[PXDNL](PXDNL)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 172 | +|[RAC2](RAC2)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@hubschmannMutationalMechanismsShaping2021b]| |
|
| 173 | +|[RANBP6](RANBP6)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 174 | +|[RBP3](RBP3)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 175 | +|[RET](RET)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 176 | +|[REV3L](REV3L)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 177 | +|[RNF144B](RNF144B)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 178 | +|[RPL10](RPL10)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 179 | +|[S1PR2](S1PR2)|2, aSHM|[Study Overview](papers/muppidiLossSignalingGa132014b)[@muppidiLossSignalingGa132014b]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 180 | +|[SAL3](SAL3)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 181 | +|[SALL3](SALL3)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|[@zhangGenomicLandscapeMantle2014]| |
|
| 182 | +|[SAPS2](SAPS2)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 183 | +|[SBF1](SBF1)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 184 | +|[SF3B1](SF3B1)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 185 | +|[SHANK1](SHANK1)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 186 | +|[SLC29A2](SLC29A2)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 187 | +|[SNTB2](SNTB2)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 188 | +|[SYNGAP1](SYNGAP1)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 189 | +|[TBC1D9B](TBC1D9B)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 190 | +|[TET2](TET2)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@albuquerqueEnhancingKnowledgeDiscovery2017a]| |
|
| 191 | +|[TIGD6](TIGD6)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 192 | +|[TOP2A](TOP2A)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 193 | +|[TPST2](TPST2)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 194 | +|[TTN](TTN)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 195 | +|[VWA7](VWA7)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 196 | +|[WDR7](WDR7)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 197 | +|[WDR90](WDR90)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 198 | +|[WHAMM](WHAMM)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 199 | +|[WNK2](WNK2)|2|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|| |
|
| 200 | +|[YY1AP1](YY1AP1)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|| |
|
| 201 | +|[ZAN](ZAN)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 202 | +|[ZBTB7A](ZBTB7A)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 203 | +|[ZFP36L1](ZFP36L1)|2, aSHM|[Study Overview](papers/paneaWholeGenomeLandscape2019)[@paneaWholeGenomeLandscape2019]|[@morinFrequentMutationHistonemodifying2011; @reichelFlowSortingExome2015a]| |
|
| 204 | +|[ZNF229](ZNF229)|2|[Study Overview](papers/loveGeneticLandscapeMutations2012)[@loveGeneticLandscapeMutations2012]|| |
|
| 205 | +|[ZNF85](ZNF85)|2|[Study Overview](papers/burkhardtClinicalRelevanceMolecular2022b)[@burkhardtClinicalRelevanceMolecular2022b]|| |
|
| 209 | 206 | |
| 210 | 207 | |
| 211 | 208 | # References |
DLBCL_genes.md
| ... | ... | @@ -11,340 +11,358 @@ link-citations: true |
| 11 | 11 | |
| 12 | 12 | ## Tier 1 DLBCL genes |
| 13 | 13 | |
| 14 | -### *129 total* |
|
| 14 | +### *127 total* |
|
| 15 | 15 | |
| 16 | 16 | |Gene|Tier| First DLBCL evidence | Other entities | |
| 17 | 17 | |:-:|:-:|:-|:-| |
| 18 | -|[ACTB](ACTB)|1, aSHM|[@lohrDiscoveryPrioritizationSomatic2012a]|[@wienandGenomicAnalysesFlowsorted2019b]| |
|
| 19 | -|[ACTG1](ACTG1)|1, aSHM|[@hubschmannMutationalMechanismsShaping2021b]|[@deschGenotypingCirculatingTumor2020; @spinaGeneticsNodalMarginal2016b]| |
|
| 20 | -|[ARID1A](ARID1A)|1|[@zhangGeneticHeterogeneityDiffuse2013]|[@wienandGenomicAnalysesFlowsorted2019b; @rossiCodingGenomeSplenic2012c; @loveGeneticLandscapeMutations2012; @krysiakRecurrentSomaticMutations2017b]| |
|
| 21 | -|[ATM](ATM)|1|[@reddyGeneticFunctionalDrivers2017]|[@braggioGenomicAnalysisMarginal2012; @beaLandscapeSomaticMutations2013]| |
|
| 22 | -|[B2M](B2M)|1|[@morinFrequentMutationHistonemodifying2011]|[@pararajalingamCodingNoncodingDrivers2020; @reichelFlowSortingExome2015a]| |
|
| 23 | -|[BCL10](BCL10)|1|[@morinFrequentMutationHistonemodifying2011]|[@spinaGeneticsNodalMarginal2016b; @russler-germainMutationsAssociatedProgression2023b]| |
|
| 24 | -|[BCL2](BCL2)|1, aSHM|[@tanakaFrequentIncidenceSomatic1992]|[@sarkozyMutationalLandscapeGray2021a; @burkhardtClinicalRelevanceMolecular2022b; @morinFrequentMutationHistonemodifying2011]| |
|
| 25 | -|[BCL6](BCL6)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@loveGeneticLandscapeMutations2012]| |
|
| 26 | -|[BCL7A](BCL7A)|1, aSHM|[@arthurGenomewideDiscoverySomatic2018]|[@krysiakRecurrentSomaticMutations2017b; @grandeGenomewideDiscoverySomatic2019; @reichelFlowSortingExome2015a]| |
|
| 27 | -|[BIRC6](BIRC6)|1|[@reddyGeneticFunctionalDrivers2017]|[@sarkozyMutationalLandscapeGray2021a]| |
|
| 28 | -|[BRAF](BRAF)|1|[@tiacciBRAFMutationsHairycell2011a]|[@loveGeneticLandscapeMutations2012]| |
|
| 29 | -|[BTG1](BTG1)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@sarkozyMutationalLandscapeGray2021a; @burkhardtClinicalRelevanceMolecular2022b]| |
|
| 30 | -|[BTG2](BTG2)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@loveGeneticLandscapeMutations2012]| |
|
| 31 | -|[BTK](BTK)|1|[@albuquerqueEnhancingKnowledgeDiscovery2017a]|[@krysiakRecurrentSomaticMutations2017b]| |
|
| 32 | -|[CARD11](CARD11)|1|[@lenzOncogenicCARD11Mutations2008]|[@yanBCRTLRSignaling2012a; @wuGeneticHeterogeneityPrimary2016; @morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]| |
|
| 33 | -|[CASP8](CASP8)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 34 | -|[CCND3](CCND3)|1|[@morinFrequentMutationHistonemodifying2011]|[@deschGenotypingCirculatingTumor2020; @jalladesExomeSequencingIdentifies2017; @richterRecurrentMutationID32012a]| |
|
| 35 | -|[CD58](CD58)|1|[@morinFrequentMutationHistonemodifying2011]|[@schneiderAlterationsCD58Gene2015a]| |
|
| 36 | -|[CD70](CD70)|1|[@morinFrequentMutationHistonemodifying2011]|[@russler-germainMutationsAssociatedProgression2023b]| |
|
| 37 | -|[CD79B](CD79B)|1|[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019]| |
|
| 38 | -|[CD83](CD83)|1, aSHM|[@morinMutationalStructuralAnalysis2013]|[@russler-germainMutationsAssociatedProgression2023b; @paneaWholeGenomeLandscape2019; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 39 | -|[CDKN2A](CDKN2A)|1|[@morinMutationalStructuralAnalysis2013]|[@grandeGenomewideDiscoverySomatic2019; @spinaGeneticsNodalMarginal2016b]| |
|
| 40 | -|[CIITA](CIITA)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@mottokGenomicAlterationsCIITA2015b]| |
|
| 41 | -|[CREBBP](CREBBP)|1|[@pasqualucciInactivatingMutationsAcetyltransferase2011a]|[@loveGeneticLandscapeMutations2012; @parryWholeExomeSequencing2013; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 42 | -|[CXCR4](CXCR4)|1, aSHM|[@khodabakhshiRecurrentTargetsAberrant2012]|[@paneaWholeGenomeLandscape2019; @krysiakRecurrentSomaticMutations2017b]| |
|
| 43 | -|[CXCR5](CXCR5)|1|[@schmitzGeneticsPathogenesisDiffuse2018a]|[@mottokIntegrativeGenomicAnalysis2019b]| |
|
| 44 | -|[DDX3X](DDX3X)|1|[@schmitzGeneticsPathogenesisDiffuse2018a]|[@mottokIntegrativeGenomicAnalysis2019b; @schmitzBurkittLymphomaPathogenesis2012]| |
|
| 45 | -|[DTX1](DTX1)|1, aSHM|[@schmitzGeneticsPathogenesisDiffuse2018a]|[@paneaWholeGenomeLandscape2019; @rossiCodingGenomeSplenic2012c; @gomezUltraDeepSequencingReveals2023]| |
|
| 46 | -|[DUSP2](DUSP2)|1, aSHM|[@morinMutationalStructuralAnalysis2013]|[@dunsCharacterizationDLBCLPMBL2021b]| |
|
| 47 | -|[EBF1](EBF1)|1, aSHM|[@bohleRoleEarlyBcell2013]|[@thomasGeneticSubgroupsInform2023; @reichelFlowSortingExome2015a]| |
|
| 48 | -|[EEF1A1](EEF1A1)|1|[@hubschmannMutationalMechanismsShaping2021b]|[@reichelFlowSortingExome2015a]| |
|
| 49 | -|[EP300](EP300)|1|[@pasqualucciInactivatingMutationsAcetyltransferase2011a]|[@rossiCodingGenomeSplenic2012c; @paneaWholeGenomeLandscape2019]| |
|
| 50 | -|[ETS1](ETS1)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019]| |
|
| 51 | -|[ETV6](ETV6)|1, aSHM|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 52 | -|[EZH2](EZH2)|1|[@morinSomaticMutationsAltering2010a]|[@loveGeneticLandscapeMutations2012; @mottokIntegrativeGenomicAnalysis2019b]| |
|
| 53 | -|[FAS](FAS)|1|[@schollMutationsRegionFAS2007]|[@spinaGeneticsNodalMarginal2016b]| |
|
| 54 | -|[FBXO11](FBXO11)|1|[@hubschmannMutationalMechanismsShaping2021b]|[@richterRecurrentMutationID32012a; @parryWholeExomeSequencing2013]| |
|
| 55 | -|[FBXW7](FBXW7)|1|[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 56 | -|[FOXO1](FOXO1)|1|[@morinFrequentMutationHistonemodifying2011]|[@schmitzBurkittLymphomaPathogenesis2012; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 57 | -|[GNA13](GNA13)|1|[@morinFrequentMutationHistonemodifying2011]|[@reichelFlowSortingExome2015a; @loveGeneticLandscapeMutations2012]| |
|
| 58 | -|[GNAI2](GNAI2)|1|[@morinMutationalStructuralAnalysis2013]|[@grandeGenomewideDiscoverySomatic2019]| |
|
| 59 | -|[GRB2](GRB2)|1|[@pasqualucciAnalysisCodingGenome2011]|[@paneaWholeGenomeLandscape2019]| |
|
| 60 | -|[GRHPR](GRHPR)|1, aSHM|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 61 | -|[HIST1H1B](HIST1H1B)|1, aSHM|[@chapuyMolecularSubtypesDiffuse2018b]|[@sarkozyMutationalLandscapeGray2021a; @krysiakRecurrentSomaticMutations2017b]| |
|
| 62 | -|[HIST1H1C](HIST1H1C)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019]| |
|
| 63 | -|[HIST1H1D](HIST1H1D)|1, aSHM|[@morinMutationalStructuralAnalysis2013]|[@jalladesExomeSequencingIdentifies2017; @krysiakRecurrentSomaticMutations2017b]| |
|
| 64 | -|[HIST1H1E](HIST1H1E)|1, aSHM|[@morinMutationalStructuralAnalysis2013]|[@grandeGenomewideDiscoverySomatic2019; @krysiakRecurrentSomaticMutations2017b; @reichelFlowSortingExome2015a]| |
|
| 65 | -|[HIST1H2AC](HIST1H2AC)|1, aSHM|[@morinMutationalStructuralAnalysis2013]|[@krysiakRecurrentSomaticMutations2017b]| |
|
| 18 | +|[ACTB](ACTB)|1, aSHM|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@wienandGenomicAnalysesFlowsorted2019b]| |
|
| 19 | +|[ACTG1](ACTG1)|1, aSHM|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@deschGenotypingCirculatingTumor2020; @spinaGeneticsNodalMarginal2016b]| |
|
| 20 | +|[ARID1A](ARID1A)|1|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@wienandGenomicAnalysesFlowsorted2019b; @loveGeneticLandscapeMutations2012; @rossiCodingGenomeSplenic2012c; @krysiakRecurrentSomaticMutations2017b]| |
|
| 21 | +|[ATM](ATM)|1|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@braggioGenomicAnalysisMarginal2012; @beaLandscapeSomaticMutations2013]| |
|
| 22 | +|[B2M](B2M)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@reichelFlowSortingExome2015a; @pararajalingamCodingNoncodingDrivers2020]| |
|
| 23 | +|[BCL10](BCL10)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@spinaGeneticsNodalMarginal2016b; @russler-germainMutationsAssociatedProgression2023b]| |
|
| 24 | +|[BCL2](BCL2)|1, aSHM|[Study Overview](papers/tanakaFrequentIncidenceSomatic1992)[@tanakaFrequentIncidenceSomatic1992]|[@burkhardtClinicalRelevanceMolecular2022b; @sarkozyMutationalLandscapeGray2021a; @morinFrequentMutationHistonemodifying2011]| |
|
| 25 | +|[BCL6](BCL6)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@loveGeneticLandscapeMutations2012]| |
|
| 26 | +|[BCL7A](BCL7A)|1, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|[@grandeGenomewideDiscoverySomatic2019; @reichelFlowSortingExome2015a; @krysiakRecurrentSomaticMutations2017b]| |
|
| 27 | +|[BIRC6](BIRC6)|1|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@sarkozyMutationalLandscapeGray2021a]| |
|
| 28 | +|[BRAF](BRAF)|1|[Study Overview](papers/tiacciBRAFMutationsHairycell2011a)[@tiacciBRAFMutationsHairycell2011a]|[@loveGeneticLandscapeMutations2012]| |
|
| 29 | +|[BTG1](BTG1)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@burkhardtClinicalRelevanceMolecular2022b; @sarkozyMutationalLandscapeGray2021a]| |
|
| 30 | +|[BTG2](BTG2)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@loveGeneticLandscapeMutations2012]| |
|
| 31 | +|[BTK](BTK)|1|[Study Overview](papers/albuquerqueEnhancingKnowledgeDiscovery2017a)[@albuquerqueEnhancingKnowledgeDiscovery2017a]|[@krysiakRecurrentSomaticMutations2017b]| |
|
| 32 | +|[CARD11](CARD11)|1|[Study Overview](papers/lenzOncogenicCARD11Mutations2008)[@lenzOncogenicCARD11Mutations2008]|[@wuGeneticHeterogeneityPrimary2016; @yanBCRTLRSignaling2012a; @paneaWholeGenomeLandscape2019; @morinFrequentMutationHistonemodifying2011]| |
|
| 33 | +|[CCND3](CCND3)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@deschGenotypingCirculatingTumor2020; @richterRecurrentMutationID32012a; @jalladesExomeSequencingIdentifies2017]| |
|
| 34 | +|[CD58](CD58)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@schneiderAlterationsCD58Gene2015a]| |
|
| 35 | +|[CD70](CD70)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@russler-germainMutationsAssociatedProgression2023b]| |
|
| 36 | +|[CD79B](CD79B)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019]| |
|
| 37 | +|[CD83](CD83)|1, aSHM|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@dunsCharacterizationDLBCLPMBL2021b; @paneaWholeGenomeLandscape2019; @russler-germainMutationsAssociatedProgression2023b]| |
|
| 38 | +|[CDKN2A](CDKN2A)|1|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@spinaGeneticsNodalMarginal2016b; @grandeGenomewideDiscoverySomatic2019]| |
|
| 39 | +|[CREBBP](CREBBP)|1|[Study Overview](papers/pasqualucciInactivatingMutationsAcetyltransferase2011a)[@pasqualucciInactivatingMutationsAcetyltransferase2011a]|[@loveGeneticLandscapeMutations2012; @dunsCharacterizationDLBCLPMBL2021b; @parryWholeExomeSequencing2013]| |
|
| 40 | +|[CXCR4](CXCR4)|1, aSHM|[Study Overview](papers/khodabakhshiRecurrentTargetsAberrant2012)[@khodabakhshiRecurrentTargetsAberrant2012]|[@krysiakRecurrentSomaticMutations2017b; @paneaWholeGenomeLandscape2019]| |
|
| 41 | +|[CXCR5](CXCR5)|1|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|[@mottokIntegrativeGenomicAnalysis2019b]| |
|
| 42 | +|[DDX3X](DDX3X)|1|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|[@schmitzBurkittLymphomaPathogenesis2012; @mottokIntegrativeGenomicAnalysis2019b]| |
|
| 43 | +|[DTX1](DTX1)|1, aSHM|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|[@rossiCodingGenomeSplenic2012c; @loveGeneticLandscapeMutations2012; @gomezUltraDeepSequencingReveals2023]| |
|
| 44 | +|[DUSP2](DUSP2)|1, aSHM|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@dunsCharacterizationDLBCLPMBL2021b]| |
|
| 45 | +|[EBF1](EBF1)|1, aSHM|[Study Overview](papers/bohleRoleEarlyBcell2013)[@bohleRoleEarlyBcell2013]|[@reichelFlowSortingExome2015a; @thomasGeneticSubgroupsInform2023]| |
|
| 46 | +|[EEF1A1](EEF1A1)|1|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@reichelFlowSortingExome2015a]| |
|
| 47 | +|[EP300](EP300)|1|[Study Overview](papers/pasqualucciInactivatingMutationsAcetyltransferase2011a)[@pasqualucciInactivatingMutationsAcetyltransferase2011a]|[@rossiCodingGenomeSplenic2012c; @paneaWholeGenomeLandscape2019]| |
|
| 48 | +|[ETS1](ETS1)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019]| |
|
| 49 | +|[ETV6](ETV6)|1, aSHM|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 50 | +|[EZH2](EZH2)|1|[Study Overview](papers/morinSomaticMutationsAltering2010a)[@morinSomaticMutationsAltering2010a]|[@loveGeneticLandscapeMutations2012; @mottokIntegrativeGenomicAnalysis2019b]| |
|
| 51 | +|[FAS](FAS)|1|[Study Overview](papers/schollMutationsRegionFAS2007)[@schollMutationsRegionFAS2007]|[@spinaGeneticsNodalMarginal2016b]| |
|
| 52 | +|[FBXO11](FBXO11)|1|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@parryWholeExomeSequencing2013; @richterRecurrentMutationID32012a]| |
|
| 53 | +|[FBXW7](FBXW7)|1|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 54 | +|[FOXO1](FOXO1)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@schmitzBurkittLymphomaPathogenesis2012; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 55 | +|[GNA13](GNA13)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@loveGeneticLandscapeMutations2012; @reichelFlowSortingExome2015a]| |
|
| 56 | +|[GNAI2](GNAI2)|1|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@grandeGenomewideDiscoverySomatic2019]| |
|
| 57 | +|[GRB2](GRB2)|1|[Study Overview](papers/pasqualucciAnalysisCodingGenome2011)[@pasqualucciAnalysisCodingGenome2011]|[@paneaWholeGenomeLandscape2019]| |
|
| 58 | +|[GRHPR](GRHPR)|1, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 59 | +|[HIST1H1B](HIST1H1B)|1, aSHM|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|[@krysiakRecurrentSomaticMutations2017b; @sarkozyMutationalLandscapeGray2021a]| |
|
| 60 | +|[HIST1H1C](HIST1H1C)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019]| |
|
| 61 | +|[HIST1H1D](HIST1H1D)|1, aSHM|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@krysiakRecurrentSomaticMutations2017b; @jalladesExomeSequencingIdentifies2017]| |
|
| 62 | +|[HIST1H1E](HIST1H1E)|1, aSHM|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@reichelFlowSortingExome2015a; @krysiakRecurrentSomaticMutations2017b; @grandeGenomewideDiscoverySomatic2019]| |
|
| 63 | +|[HIST1H2AC](HIST1H2AC)|1, aSHM|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@krysiakRecurrentSomaticMutations2017b]| |
|
| 66 | 64 | |[HIST1H2AM](HIST1H2AM)|1, aSHM||[@paneaWholeGenomeLandscape2019; @krysiakRecurrentSomaticMutations2017b]| |
| 67 | -|[HIST1H2BC](HIST1H2BC)|1, aSHM|[@reddyGeneticFunctionalDrivers2017]|[@krysiakRecurrentSomaticMutations2017b; @mottokIntegrativeGenomicAnalysis2019b]| |
|
| 68 | -|[HIST1H2BK](HIST1H2BK)|1, aSHM||[@paneaWholeGenomeLandscape2019; @rossiCodingGenomeSplenic2012c]| |
|
| 69 | -|[HIST1H3B](HIST1H3B)|1, aSHM|[@zhangGeneticHeterogeneityDiffuse2013]|[@reichelFlowSortingExome2015a]| |
|
| 70 | -|[HIST2H2BE](HIST2H2BE)|1, aSHM|[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 71 | -|[HLA-A](HLA-A)|1||[@deschGenotypingCirculatingTumor2020]| |
|
| 72 | -|[HLA-B](HLA-B)|1||[@wienandGenomicAnalysesFlowsorted2019b]| |
|
| 65 | +|[HIST1H2BC](HIST1H2BC)|1, aSHM|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@krysiakRecurrentSomaticMutations2017b; @mottokIntegrativeGenomicAnalysis2019b]| |
|
| 66 | +|[HIST1H2BK](HIST1H2BK)|1, aSHM||[@rossiCodingGenomeSplenic2012c; @paneaWholeGenomeLandscape2019]| |
|
| 67 | +|[HIST1H3B](HIST1H3B)|1, aSHM|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@reichelFlowSortingExome2015a]| |
|
| 68 | +|[HIST2H2BE](HIST2H2BE)|1, aSHM|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 69 | +|[HLA-A](HLA-A)|1|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@deschGenotypingCirculatingTumor2020]| |
|
| 70 | +|[HLA-B](HLA-B)|1|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@wienandGenomicAnalysesFlowsorted2019b]| |
|
| 73 | 71 | |[HLA-C](HLA-C)|1||[@gomezUltraDeepSequencingReveals2023]| |
| 74 | 72 | |[HLA-DMB](HLA-DMB)|1||| |
| 75 | -|[HNRNPU](HNRNPU)|1, aSHM|[@reddyGeneticFunctionalDrivers2017]|[@paneaWholeGenomeLandscape2019]| |
|
| 73 | +|[HNRNPU](HNRNPU)|1, aSHM|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@paneaWholeGenomeLandscape2019]| |
|
| 76 | 74 | |[HVCN1](HVCN1)|1||[@krysiakRecurrentSomaticMutations2017b]| |
| 77 | -|[IKZF3](IKZF3)|1|[@morinMutationalStructuralAnalysis2013]|[@paneaWholeGenomeLandscape2019]| |
|
| 78 | -|[IL4R](IL4R)|1, aSHM|[@dunsCharacterizationDLBCLPMBL2021b]|[@viganoSomaticIL4RMutations2018b]| |
|
| 79 | -|[IRF4](IRF4)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@mottokIntegrativeGenomicAnalysis2019b]| |
|
| 80 | -|[IRF8](IRF8)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019; @mottokIntegrativeGenomicAnalysis2019b]| |
|
| 81 | -|[ITPKB](ITPKB)|1, aSHM|[@schmitzGeneticsPathogenesisDiffuse2018a]|[@reichelFlowSortingExome2015a]| |
|
| 82 | -|[KLF2](KLF2)|1, aSHM|[@pasqualucciAnalysisCodingGenome2011]|[@jalladesExomeSequencingIdentifies2017; @deschGenotypingCirculatingTumor2020]| |
|
| 83 | -|[KLHL14](KLHL14)|1|[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 84 | -|[KLHL6](KLHL6)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@ganapathiGeneticLandscapeDural2016; @paneaWholeGenomeLandscape2019]| |
|
| 85 | -|[KMT2C](KMT2C)|1|[@zhangGeneticHeterogeneityDiffuse2013]|[@sarkozyMutationalLandscapeGray2021a; @zhouSporadicEndemicBurkitt2019; @zhangGenomicLandscapeMantle2014]| |
|
| 86 | -|[KMT2D](KMT2D)|1|[@morinFrequentMutationHistonemodifying2011]|[@grandeGenomewideDiscoverySomatic2019; @rossiCodingGenomeSplenic2012c; @beaLandscapeSomaticMutations2013; @deschGenotypingCirculatingTumor2020]| |
|
| 87 | -|[KRAS](KRAS)|1|[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 88 | -|[LCOR](LCOR)|1|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 89 | -|[LTB](LTB)|1, aSHM|[@chapuyMolecularSubtypesDiffuse2018b]|[@paneaWholeGenomeLandscape2019; @deschGenotypingCirculatingTumor2020]| |
|
| 90 | -|[MEF2B](MEF2B)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@beaLandscapeSomaticMutations2013]| |
|
| 91 | -|[MEF2C](MEF2C)|1, aSHM|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 92 | -|[MGA](MGA)|1|[@zhangGeneticHeterogeneityDiffuse2013]|[@jalladesExomeSequencingIdentifies2017]| |
|
| 93 | -|[MPEG1](MPEG1)|1|[@morinMutationalStructuralAnalysis2013]|| |
|
| 94 | -|[MS4A1](MS4A1)|1, aSHM|[@rushtonGeneticEvolutionaryPatterns2020]|[@mottokIntegrativeGenomicAnalysis2019b]| |
|
| 95 | -|[MTOR](MTOR)|1|[@zhangGeneticHeterogeneityDiffuse2013]|[@paneaWholeGenomeLandscape2019]| |
|
| 96 | -|[MYC](MYC)|1, aSHM|[@pasqualucciHypermutationMultipleProtooncogenes2001a]|[@jalladesExomeSequencingIdentifies2017; @johnstonCmycHypermutationBurkitt1992; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 97 | -|[MYD88](MYD88)|1|[@ngoOncogenicallyActiveMYD882011a]|[@yanBCRTLRSignaling2012a]| |
|
| 98 | -|[NFKBIA](NFKBIA)|1|[@lakeMutationsNFKBIAEncoding2009]|[@russler-germainMutationsAssociatedProgression2023b; @wienandGenomicAnalysesFlowsorted2019b]| |
|
| 99 | -|[NFKBIE](NFKBIE)|1|[@morinGeneticLandscapesRelapsed2016]|[@pararajalingamCodingNoncodingDrivers2020; @mansouriFrequentNFKBIEDeletions2016]| |
|
| 100 | -|[NFKBIZ](NFKBIZ)|1, noncoding|[@morinGeneticLandscapesRelapsed2016]|| |
|
| 101 | -|[NOL9](NOL9)|1, aSHM|[@schmitzGeneticsPathogenesisDiffuse2018a]|[@spinaGeneticsNodalMarginal2016b]| |
|
| 102 | -|[NOTCH1](NOTCH1)|1|[@pasqualucciAnalysisCodingGenome2011]|[@loveGeneticLandscapeMutations2012; @rossiCodingGenomeSplenic2012c; @beaLandscapeSomaticMutations2013]| |
|
| 103 | -|[NOTCH2](NOTCH2)|1|[@troenNOTCH2MutationsMarginal2008]|[@rossiCodingGenomeSplenic2012c; @beaLandscapeSomaticMutations2013; @paneaWholeGenomeLandscape2019]| |
|
| 104 | -|[OSBPL10](OSBPL10)|1, aSHM|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 105 | -|[P2RY8](P2RY8)|1|[@lohrDiscoveryPrioritizationSomatic2012a]|[@muppidiLossSignalingGa132014b]| |
|
| 106 | -|[PIM1](PIM1)|1, aSHM|[@pasqualucciHypermutationMultipleProtooncogenes2001a]|[@burkhardtClinicalRelevanceMolecular2022b; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 107 | -|[PIM2](PIM2)|1, aSHM|[@arthurGenomewideDiscoverySomatic2018]|[@reichelFlowSortingExome2015a]| |
|
| 75 | +|[IKZF3](IKZF3)|1|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@paneaWholeGenomeLandscape2019]| |
|
| 76 | +|[IL4R](IL4R)|1, aSHM|[Study Overview](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|[@viganoSomaticIL4RMutations2018b]| |
|
| 77 | +|[IRF4](IRF4)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@mottokIntegrativeGenomicAnalysis2019b]| |
|
| 78 | +|[IRF8](IRF8)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@mottokIntegrativeGenomicAnalysis2019b; @paneaWholeGenomeLandscape2019]| |
|
| 79 | +|[ITPKB](ITPKB)|1, aSHM|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|[@reichelFlowSortingExome2015a]| |
|
| 80 | +|[KLF2](KLF2)|1, aSHM|[Study Overview](papers/pasqualucciAnalysisCodingGenome2011)[@pasqualucciAnalysisCodingGenome2011]|[@deschGenotypingCirculatingTumor2020; @jalladesExomeSequencingIdentifies2017]| |
|
| 81 | +|[KLHL14](KLHL14)|1|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 82 | +|[KLHL6](KLHL6)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@ganapathiGeneticLandscapeDural2016; @paneaWholeGenomeLandscape2019]| |
|
| 83 | +|[KMT2C](KMT2C)|1|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@sarkozyMutationalLandscapeGray2021a; @zhangGenomicLandscapeMantle2014; @zhouSporadicEndemicBurkitt2019]| |
|
| 84 | +|[KMT2D](KMT2D)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@beaLandscapeSomaticMutations2013; @grandeGenomewideDiscoverySomatic2019; @deschGenotypingCirculatingTumor2020; @rossiCodingGenomeSplenic2012c]| |
|
| 85 | +|[KRAS](KRAS)|1|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 86 | +|[LCOR](LCOR)|1|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 87 | +|[LTB](LTB)|1, aSHM|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|[@deschGenotypingCirculatingTumor2020; @paneaWholeGenomeLandscape2019]| |
|
| 88 | +|[MEF2B](MEF2B)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@beaLandscapeSomaticMutations2013]| |
|
| 89 | +|[MEF2C](MEF2C)|1, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 90 | +|[MGA](MGA)|1|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@jalladesExomeSequencingIdentifies2017]| |
|
| 91 | +|[MPEG1](MPEG1)|1|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 92 | +|[MS4A1](MS4A1)|1, aSHM|[Study Overview](papers/rushtonGeneticEvolutionaryPatterns2020)[@rushtonGeneticEvolutionaryPatterns2020]|[@mottokIntegrativeGenomicAnalysis2019b]| |
|
| 93 | +|[MTOR](MTOR)|1|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@paneaWholeGenomeLandscape2019]| |
|
| 94 | +|[MYC](MYC)|1, aSHM|[Study Overview](papers/pasqualucciHypermutationMultipleProtooncogenes2001a)[@pasqualucciHypermutationMultipleProtooncogenes2001a]|[@dunsCharacterizationDLBCLPMBL2021b; @jalladesExomeSequencingIdentifies2017; @johnstonCmycHypermutationBurkitt1992]| |
|
| 95 | +|[MYD88](MYD88)|1|[Study Overview](papers/ngoOncogenicallyActiveMYD882011a)[@ngoOncogenicallyActiveMYD882011a]|[@yanBCRTLRSignaling2012a]| |
|
| 96 | +|[NFKBIA](NFKBIA)|1|[Study Overview](papers/lakeMutationsNFKBIAEncoding2009)[@lakeMutationsNFKBIAEncoding2009]|[@wienandGenomicAnalysesFlowsorted2019b; @russler-germainMutationsAssociatedProgression2023b]| |
|
| 97 | +|[NFKBIE](NFKBIE)|1|[Study Overview](papers/morinGeneticLandscapesRelapsed2016)[@morinGeneticLandscapesRelapsed2016]|[@pararajalingamCodingNoncodingDrivers2020; @mansouriFrequentNFKBIEDeletions2016]| |
|
| 98 | +|[NFKBIZ](NFKBIZ)|1, noncoding|[Study Overview](papers/morinGeneticLandscapesRelapsed2016)[@morinGeneticLandscapesRelapsed2016]|| |
|
| 99 | +|[NOL9](NOL9)|1, aSHM|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|[@spinaGeneticsNodalMarginal2016b]| |
|
| 100 | +|[NOTCH1](NOTCH1)|1|[Study Overview](papers/pasqualucciAnalysisCodingGenome2011)[@pasqualucciAnalysisCodingGenome2011]|[@loveGeneticLandscapeMutations2012; @rossiCodingGenomeSplenic2012c; @beaLandscapeSomaticMutations2013]| |
|
| 101 | +|[NOTCH2](NOTCH2)|1|[Study Overview](papers/troenNOTCH2MutationsMarginal2008)[@troenNOTCH2MutationsMarginal2008]|[@beaLandscapeSomaticMutations2013; @rossiCodingGenomeSplenic2012c; @paneaWholeGenomeLandscape2019]| |
|
| 102 | +|[OSBPL10](OSBPL10)|1, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 103 | +|[P2RY8](P2RY8)|1|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@muppidiLossSignalingGa132014b]| |
|
| 104 | +|[PIM1](PIM1)|1, aSHM|[Study Overview](papers/pasqualucciHypermutationMultipleProtooncogenes2001a)[@pasqualucciHypermutationMultipleProtooncogenes2001a]|[@dunsCharacterizationDLBCLPMBL2021b; @burkhardtClinicalRelevanceMolecular2022b]| |
|
| 105 | +|[PIM2](PIM2)|1, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|[@reichelFlowSortingExome2015a]| |
|
| 108 | 106 | |[POU2AF1](POU2AF1)|1, aSHM||[@krysiakRecurrentSomaticMutations2017b]| |
| 109 | -|[POU2F2](POU2F2)|1|[@zhangGeneticHeterogeneityDiffuse2013]|[@krysiakRecurrentSomaticMutations2017b]| |
|
| 110 | -|[PRDM1](PRDM1)|1|[@pasqualucciInactivationPRDM1BLIMP12006a]|| |
|
| 107 | +|[POU2F2](POU2F2)|1|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@krysiakRecurrentSomaticMutations2017b]| |
|
| 108 | +|[PRDM1](PRDM1)|1|[Study Overview](papers/pasqualucciInactivationPRDM1BLIMP12006a)[@pasqualucciInactivationPRDM1BLIMP12006a]|| |
|
| 111 | 109 | |[PTEN](PTEN)|1||[@loveGeneticLandscapeMutations2012]| |
| 112 | 110 | |[PTPRD](PTPRD)|1||[@spinaGeneticsNodalMarginal2016b]| |
| 113 | -|[RB1](RB1)|1|[@morinMutationalStructuralAnalysis2013]|[@zhangGenomicLandscapeMantle2014]| |
|
| 111 | +|[RB1](RB1)|1|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@zhangGenomicLandscapeMantle2014]| |
|
| 114 | 112 | |[RFX7](RFX7)|1||[@grandeGenomewideDiscoverySomatic2019]| |
| 115 | 113 | |[RHOA](RHOA)|1||[@richterRecurrentMutationID32012a]| |
| 116 | -|[RRAGC](RRAGC)|1|[@okosunRecurrentMTORC1activatingRRAGC2016a]|| |
|
| 117 | -|[S1PR2](S1PR2)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@muppidiLossSignalingGa132014b]| |
|
| 118 | -|[SETD1B](SETD1B)|1|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 114 | +|[RRAGC](RRAGC)|1|[Study Overview](papers/okosunRecurrentMTORC1activatingRRAGC2016a)[@okosunRecurrentMTORC1activatingRRAGC2016a]|| |
|
| 115 | +|[S1PR2](S1PR2)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@muppidiLossSignalingGa132014b]| |
|
| 116 | +|[SETD1B](SETD1B)|1|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 119 | 117 | |[SF3B1](SF3B1)|1||[@loveGeneticLandscapeMutations2012]| |
| 120 | -|[SGK1](SGK1)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@dunsCharacterizationDLBCLPMBL2021b]| |
|
| 121 | -|[SIN3A](SIN3A)|1||[@grandeGenomewideDiscoverySomatic2019; @rossiCodingGenomeSplenic2012c]| |
|
| 122 | -|[SMARCA4](SMARCA4)|1|[@zhangGeneticHeterogeneityDiffuse2013]|[@nadeuGenomicEpigenomicInsights2020b; @krysiakRecurrentSomaticMutations2017b; @richterRecurrentMutationID32012a]| |
|
| 123 | -|[SOCS1](SOCS1)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@wenigerMutationsTumorSuppressor2006a]| |
|
| 124 | -|[SPEN](SPEN)|1|[@rossiCodingGenomeSplenic2012c]|[@sarkozyMutationalLandscapeGray2021a]| |
|
| 125 | -|[STAT3](STAT3)|1|[@ohgamiSTAT3MutationsAre2014]|| |
|
| 126 | -|[STAT6](STAT6)|1|[@yildizActivatingSTAT6Mutations2015c]|[@ritzRecurrentMutationsSTAT62009a]| |
|
| 127 | -|[TAF1](TAF1)|1|[@morinMutationalStructuralAnalysis2013]|[@spinaGeneticsNodalMarginal2016b]| |
|
| 128 | -|[TBL1XR1](TBL1XR1)|1|[@mareschalWholeExomeSequencing2016]|[@rossiCodingGenomeSplenic2012c]| |
|
| 129 | -|[TET2](TET2)|1|[@albuquerqueEnhancingKnowledgeDiscovery2017a]|[@paneaWholeGenomeLandscape2019]| |
|
| 130 | -|[TMEM30A](TMEM30A)|1|[@morinFrequentMutationHistonemodifying2011]|| |
|
| 131 | -|[TMSB4X](TMSB4X)|1, aSHM|[@albuquerqueEnhancingKnowledgeDiscovery2017a]|| |
|
| 132 | -|[TNFAIP3](TNFAIP3)|1|[@compagnoMutationsMultipleGenes2009a]|[@schmitzTNFAIP3A20Tumor2009a; @rossiAlterationBIRC3Multiple2011a]| |
|
| 133 | -|[TNFRSF14](TNFRSF14)|1|[@cheungAcquiredTNFRSF14Mutations2010a]|[@spinaGeneticsNodalMarginal2016b]| |
|
| 134 | -|[TOX](TOX)|1|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 135 | -|[TP53](TP53)|1||[@morinFrequentMutationHistonemodifying2011; @tiacciPervasiveMutationsJAKSTAT2018b; @rossiCodingGenomeSplenic2012c; @wildaInactivationARFMDM2p53Pathway2004; @beaLandscapeSomaticMutations2013]| |
|
| 136 | -|[TRRAP](TRRAP)|1|[@parryWholeExomeSequencing2013]|[@rossiCodingGenomeSplenic2012c]| |
|
| 137 | -|[UBE2A](UBE2A)|1|[@reddyGeneticFunctionalDrivers2017]|[@reichelFlowSortingExome2015a]| |
|
| 138 | -|[UNC5C](UNC5C)|1||| |
|
| 118 | +|[SGK1](SGK1)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@dunsCharacterizationDLBCLPMBL2021b]| |
|
| 119 | +|[SIN3A](SIN3A)|1||[@rossiCodingGenomeSplenic2012c; @grandeGenomewideDiscoverySomatic2019]| |
|
| 120 | +|[SMARCA4](SMARCA4)|1|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@richterRecurrentMutationID32012a; @krysiakRecurrentSomaticMutations2017b; @nadeuGenomicEpigenomicInsights2020b]| |
|
| 121 | +|[SOCS1](SOCS1)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@wenigerMutationsTumorSuppressor2006a]| |
|
| 122 | +|[SPEN](SPEN)|1|[Study Overview](papers/rossiCodingGenomeSplenic2012c)[@rossiCodingGenomeSplenic2012c]|[@sarkozyMutationalLandscapeGray2021a]| |
|
| 123 | +|[STAT3](STAT3)|1|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 124 | +|[STAT6](STAT6)|1|[Study Overview](papers/yildizActivatingSTAT6Mutations2015c)[@yildizActivatingSTAT6Mutations2015c]|[@ritzRecurrentMutationsSTAT62009a]| |
|
| 125 | +|[TAF1](TAF1)|1|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@spinaGeneticsNodalMarginal2016b]| |
|
| 126 | +|[TBL1XR1](TBL1XR1)|1|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@rossiCodingGenomeSplenic2012c]| |
|
| 127 | +|[TET2](TET2)|1|[Study Overview](papers/albuquerqueEnhancingKnowledgeDiscovery2017a)[@albuquerqueEnhancingKnowledgeDiscovery2017a]|[@paneaWholeGenomeLandscape2019]| |
|
| 128 | +|[TMEM30A](TMEM30A)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|| |
|
| 129 | +|[TMSB4X](TMSB4X)|1, aSHM|[Study Overview](papers/albuquerqueEnhancingKnowledgeDiscovery2017a)[@albuquerqueEnhancingKnowledgeDiscovery2017a]|| |
|
| 130 | +|[TNFAIP3](TNFAIP3)|1|[Study Overview](papers/compagnoMutationsMultipleGenes2009a)[@compagnoMutationsMultipleGenes2009a]|[@schmitzTNFAIP3A20Tumor2009a; @rossiAlterationBIRC3Multiple2011a]| |
|
| 131 | +|[TNFRSF14](TNFRSF14)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@cheungAcquiredTNFRSF14Mutations2010a; @spinaGeneticsNodalMarginal2016b]| |
|
| 132 | +|[TOX](TOX)|1|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 133 | +|[TP53](TP53)|1|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@rossiCodingGenomeSplenic2012c; @morinFrequentMutationHistonemodifying2011; @tiacciPervasiveMutationsJAKSTAT2018b; @wildaInactivationARFMDM2p53Pathway2004; @beaLandscapeSomaticMutations2013]| |
|
| 134 | +|[TRRAP](TRRAP)|1|[Study Overview](papers/parryWholeExomeSequencing2013)[@parryWholeExomeSequencing2013]|[@rossiCodingGenomeSplenic2012c]| |
|
| 135 | +|[UBE2A](UBE2A)|1|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@reichelFlowSortingExome2015a]| |
|
| 136 | +|[UNC5C](UNC5C)|1|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 139 | 137 | |[USP7](USP7)|1||[@grandeGenomewideDiscoverySomatic2019]| |
| 140 | -|[VPS13B](VPS13B)|1||| |
|
| 141 | -|[WEE1](WEE1)|1|[@schmitzGeneticsPathogenesisDiffuse2018a]|[@reichelFlowSortingExome2015a]| |
|
| 142 | -|[XPO1](XPO1)|1|[@mareschalWholeExomeSequencing2016]|[@jardinRecurrentMutationsExportin2016a]| |
|
| 143 | -|[ZC3H12A](ZC3H12A)|1|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 144 | -|[ZFP36L1](ZFP36L1)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@reichelFlowSortingExome2015a; @paneaWholeGenomeLandscape2019]| |
|
| 145 | -|[ZNF292](ZNF292)|1|[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 146 | -|[ZNF608](ZNF608)|1, aSHM|[@zhangGeneticHeterogeneityDiffuse2013]|[@krysiakRecurrentSomaticMutations2017b]| |
|
| 138 | +|[VPS13B](VPS13B)|1|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 139 | +|[WEE1](WEE1)|1|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|[@reichelFlowSortingExome2015a]| |
|
| 140 | +|[XPO1](XPO1)|1|[Study Overview](papers/mareschalWholeExomeSequencing2016)[@mareschalWholeExomeSequencing2016]|[@jardinRecurrentMutationsExportin2016a]| |
|
| 141 | +|[ZC3H12A](ZC3H12A)|1|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 142 | +|[ZFP36L1](ZFP36L1)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019; @reichelFlowSortingExome2015a]| |
|
| 143 | +|[ZNF292](ZNF292)|1|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 144 | +|[ZNF608](ZNF608)|1, aSHM|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@krysiakRecurrentSomaticMutations2017b]| |
|
| 147 | 145 | |
| 148 | 146 | ## Tier 2 DLBCL genes |
| 149 | 147 | |
| 150 | -### *194 total* |
|
| 148 | +### *215 total* |
|
| 151 | 149 | |
| 152 | 150 | |Gene|Tier| First DLBCL evidence | Other entities | |
| 153 | 151 | |:-:|:-:|:-|:-| |
| 154 | -|[ABI3BP](ABI3BP)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 155 | -|[ADAMTS1](ADAMTS1)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 156 | -|[AICDA](AICDA)|2, aSHM|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 157 | -|[ANKRD12](ANKRD12)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 158 | -|[ANKRD17](ANKRD17)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 159 | -|[ARID1B](ARID1B)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 160 | -|[ARID5B](ARID5B)|2|[@reddyGeneticFunctionalDrivers2017]|[@gomezUltraDeepSequencingReveals2023]| |
|
| 161 | -|[ATR](ATR)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 152 | +|[ABI3BP](ABI3BP)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 153 | +|[ADAMTS1](ADAMTS1)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 154 | +|[AICDA](AICDA)|2, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 155 | +|[ANKRD12](ANKRD12)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 156 | +|[ANKRD17](ANKRD17)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 157 | +|[ARID1B](ARID1B)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 158 | +|[ARID5B](ARID5B)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@gomezUltraDeepSequencingReveals2023]| |
|
| 159 | +|[ATR](ATR)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 162 | 160 | |[BCL11A](BCL11A)|2, aSHM||| |
| 163 | 161 | |[BCOR](BCOR)|2||[@nadeuGenomicEpigenomicInsights2020b; @jalladesExomeSequencingIdentifies2017]| |
| 164 | -|[BCR](BCR)|2, aSHM||| |
|
| 165 | -|[BIRC3](BIRC3)|2, aSHM|[@arthurGenomewideDiscoverySomatic2018]|[@beaLandscapeSomaticMutations2013; @rossiAlterationBIRC3Multiple2011a; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 162 | +|[BCR](BCR)|2, aSHM|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 163 | +|[BIRC3](BIRC3)|2, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|[@rossiAlterationBIRC3Multiple2011a; @dunsCharacterizationDLBCLPMBL2021b; @beaLandscapeSomaticMutations2013]| |
|
| 166 | 164 | |[BLK](BLK)|2, aSHM||| |
| 167 | -|[BRINP3](BRINP3)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 168 | -|[BTBD3](BTBD3)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 169 | -|[CADPS2](CADPS2)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 170 | -|[CBLB](CBLB)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 171 | -|[CCL4](CCL4)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 172 | -|[CD22](CD22)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 173 | -|[CD274](CD274)|2|[@morinFrequentMutationHistonemodifying2011]|| |
|
| 174 | -|[CD36](CD36)|2|[@pasqualucciAnalysisCodingGenome2011]|| |
|
| 175 | -|[CD44](CD44)|2, aSHM|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 176 | -|[CD74](CD74)|2, aSHM|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 177 | -|[CDC73](CDC73)|2|[@reddyGeneticFunctionalDrivers2017]|[@loveGeneticLandscapeMutations2012]| |
|
| 178 | -|[CDH9](CDH9)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 179 | -|[CHD1](CHD1)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 180 | -|[CHD8](CHD8)|2|[@reddyGeneticFunctionalDrivers2017]|[@grandeGenomewideDiscoverySomatic2019]| |
|
| 181 | -|[CHST2](CHST2)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 182 | -|[CNOT2](CNOT2)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 183 | -|[CNTNAP5](CNTNAP5)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 184 | -|[COQ7](COQ7)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 185 | -|[CRIP1](CRIP1)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 186 | -|[DAZAP1](DAZAP1)|2|[@pararajalingamCodingNoncodingDrivers2020]|| |
|
| 187 | -|[DCAF6](DCAF6)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 188 | -|[DDX10](DDX10)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 189 | -|[DHX16](DHX16)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 190 | -|[DICER1](DICER1)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 191 | -|[DNAH5](DNAH5)|2|[@morinMutationalStructuralAnalysis2013]|[@jalladesExomeSequencingIdentifies2017]| |
|
| 192 | -|[DNM2](DNM2)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 193 | -|[DNMT3A](DNMT3A)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 194 | -|[DOCK1](DOCK1)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 195 | -|[DSG4](DSG4)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 165 | +|[BRINP3](BRINP3)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 166 | +|[BTBD3](BTBD3)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 167 | +|[CADPS2](CADPS2)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 168 | +|[CASP8](CASP8)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 169 | +|[CBLB](CBLB)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 170 | +|[CCL4](CCL4)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 171 | +|[CD22](CD22)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 172 | +|[CD274](CD274)|2|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|| |
|
| 173 | +|[CD36](CD36)|2|[Study Overview](papers/pasqualucciAnalysisCodingGenome2011)[@pasqualucciAnalysisCodingGenome2011]|| |
|
| 174 | +|[CD44](CD44)|2, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 175 | +|[CD74](CD74)|2, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 176 | +|[CDC73](CDC73)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@loveGeneticLandscapeMutations2012]| |
|
| 177 | +|[CDH9](CDH9)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 178 | +|[CHD1](CHD1)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 179 | +|[CHD8](CHD8)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@grandeGenomewideDiscoverySomatic2019]| |
|
| 180 | +|[CHST2](CHST2)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 181 | +|[CIITA](CIITA)|2, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@mottokGenomicAlterationsCIITA2015b]| |
|
| 182 | +|[CNOT2](CNOT2)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 183 | +|[CNTNAP5](CNTNAP5)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 184 | +|[COQ7](COQ7)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 185 | +|[CPS1](CPS1)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 186 | +|[CRIP1](CRIP1)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 187 | +|[DAZAP1](DAZAP1)|2|[Study Overview](papers/pararajalingamCodingNoncodingDrivers2020)[@pararajalingamCodingNoncodingDrivers2020]|| |
|
| 188 | +|[DCAF6](DCAF6)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 189 | +|[DDX10](DDX10)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 190 | +|[DHX16](DHX16)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 191 | +|[DICER1](DICER1)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 192 | +|[DNAH5](DNAH5)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@jalladesExomeSequencingIdentifies2017]| |
|
| 193 | +|[DNM2](DNM2)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 194 | +|[DNMT3A](DNMT3A)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 195 | +|[DOCK1](DOCK1)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 196 | +|[DSG4](DSG4)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 196 | 197 | |[EIF2AK3](EIF2AK3)|2, aSHM||| |
| 197 | 198 | |[EZR](EZR)|2, aSHM||[@deschGenotypingCirculatingTumor2020]| |
| 198 | 199 | |[FAM102A](FAM102A)|2, aSHM||| |
| 199 | -|[FAM38B](FAM38B)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 200 | +|[FAM38B](FAM38B)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 200 | 201 | |[FANK1](FANK1)|2, aSHM||| |
| 201 | -|[FAT4](FAT4)|2|[@morinMutationalStructuralAnalysis2013]|[@parryWholeExomeSequencing2013; @zhangGenomicLandscapeMantle2014]| |
|
| 202 | +|[FAT4](FAT4)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@zhangGenomicLandscapeMantle2014; @parryWholeExomeSequencing2013]| |
|
| 202 | 203 | |[FCRL3](FCRL3)|2, aSHM||| |
| 203 | 204 | |[FNBP1](FNBP1)|2, aSHM||| |
| 204 | -|[FNDC1](FNDC1)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 205 | -|[FOXC1](FOXC1)|2|[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 206 | -|[FOXP1](FOXP1)|2, aSHM|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 207 | -|[FUBP1](FUBP1)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 208 | -|[FUT5](FUT5)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 209 | -|[GABRA2](GABRA2)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 210 | -|[GAK](GAK)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 211 | -|[GNAS](GNAS)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 212 | -|[GOLGA5](GOLGA5)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 213 | -|[GPC5](GPC5)|2|[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 214 | -|[GSG2](GSG2)|2|[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 215 | -|[HDAC7](HDAC7)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 216 | -|[HIST1H2AG](HIST1H2AG)|2, aSHM|[@morinMutationalStructuralAnalysis2013]|[@rossiCodingGenomeSplenic2012c; @paneaWholeGenomeLandscape2019; @krysiakRecurrentSomaticMutations2017b]| |
|
| 205 | +|[FNDC1](FNDC1)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 206 | +|[FOXC1](FOXC1)|2|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 207 | +|[FOXP1](FOXP1)|2, aSHM|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 208 | +|[FUBP1](FUBP1)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 209 | +|[FUT5](FUT5)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 210 | +|[GABRA1](GABRA1)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 211 | +|[GABRA2](GABRA2)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 212 | +|[GAK](GAK)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 213 | +|[GNAS](GNAS)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 214 | +|[GOLGA5](GOLGA5)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 215 | +|[GPC5](GPC5)|2|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 216 | +|[GSG2](GSG2)|2|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 217 | +|[H1FOO](H1FOO)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 218 | +|[HDAC7](HDAC7)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 219 | +|[HIST1H2AG](HIST1H2AG)|2, aSHM|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@rossiCodingGenomeSplenic2012c; @krysiakRecurrentSomaticMutations2017b; @paneaWholeGenomeLandscape2019]| |
|
| 220 | +|[HIST1H2AL](HIST1H2AL)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 221 | +|[HIST1H2BO](HIST1H2BO)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 217 | 222 | |[HLA-DMA](HLA-DMA)|2||| |
| 218 | -|[HLA-DQA1](HLA-DQA1)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 219 | -|[HNF1B](HNF1B)|2|[@pasqualucciAnalysisCodingGenome2011]|| |
|
| 220 | -|[HNRNPH1](HNRNPH1)|2, noncoding|[@pararajalingamCodingNoncodingDrivers2020]|| |
|
| 221 | -|[HRAS](HRAS)|2|[@reddyGeneticFunctionalDrivers2017]|[@jalladesExomeSequencingIdentifies2017]| |
|
| 222 | -|[ID3](ID3)|2|[@schmitzBurkittLymphomaPathogenesis2012]|[@spinaGeneticsNodalMarginal2016b; @richterRecurrentMutationID32012a]| |
|
| 223 | -|[IER2](IER2)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 224 | -|[IFNGR1](IFNGR1)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 225 | -|[IGLL5](IGLL5)|2, aSHM||[@russler-germainMutationsAssociatedProgression2023b; @deschGenotypingCirculatingTumor2020; @paneaWholeGenomeLandscape2019]| |
|
| 226 | -|[IKBKB](IKBKB)|2|[@reddyGeneticFunctionalDrivers2017]|[@rossiAlterationBIRC3Multiple2011a; @wienandGenomicAnalysesFlowsorted2019b]| |
|
| 227 | -|[IKBKE](IKBKE)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 223 | +|[HLA-DQA1](HLA-DQA1)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 224 | +|[HNF1B](HNF1B)|2|[Study Overview](papers/pasqualucciAnalysisCodingGenome2011)[@pasqualucciAnalysisCodingGenome2011]|| |
|
| 225 | +|[HNRNPH1](HNRNPH1)|2, noncoding|[Study Overview](papers/pararajalingamCodingNoncodingDrivers2020)[@pararajalingamCodingNoncodingDrivers2020]|| |
|
| 226 | +|[HRAS](HRAS)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@jalladesExomeSequencingIdentifies2017]| |
|
| 227 | +|[ID3](ID3)|2|[Study Overview](papers/schmitzBurkittLymphomaPathogenesis2012)[@schmitzBurkittLymphomaPathogenesis2012]|[@spinaGeneticsNodalMarginal2016b; @richterRecurrentMutationID32012a]| |
|
| 228 | +|[IER2](IER2)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 229 | +|[IFNGR1](IFNGR1)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 230 | +|[IGLL5](IGLL5)|2, aSHM||[@deschGenotypingCirculatingTumor2020; @paneaWholeGenomeLandscape2019; @russler-germainMutationsAssociatedProgression2023b]| |
|
| 231 | +|[IKBKB](IKBKB)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@wienandGenomicAnalysesFlowsorted2019b; @rossiAlterationBIRC3Multiple2011a]| |
|
| 232 | +|[IKBKE](IKBKE)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 228 | 233 | |[IL16](IL16)|2||| |
| 229 | -|[IL6](IL6)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 230 | -|[INO80](INO80)|2|[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 231 | -|[IRF1](IRF1)|2, aSHM|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 232 | -|[JAK1](JAK1)|2|[@zhangGeneticHeterogeneityDiffuse2013]|[@mottokIntegrativeGenomicAnalysis2019b]| |
|
| 233 | -|[JAK3](JAK3)|2|[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 234 | -|[JUNB](JUNB)|2|[@reddyGeneticFunctionalDrivers2017]|[@mottokIntegrativeGenomicAnalysis2019b]| |
|
| 235 | -|[KCMF1](KCMF1)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 236 | -|[KLHL21](KLHL21)|2|[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 237 | -|[LAMA5](LAMA5)|2|[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 234 | +|[IL6](IL6)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 235 | +|[INO80](INO80)|2|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 236 | +|[IRF1](IRF1)|2, aSHM|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 237 | +|[JAK1](JAK1)|2|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@mottokIntegrativeGenomicAnalysis2019b]| |
|
| 238 | +|[JAK3](JAK3)|2|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 239 | +|[JUNB](JUNB)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@mottokIntegrativeGenomicAnalysis2019b]| |
|
| 240 | +|[KCMF1](KCMF1)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 241 | +|[KLHL21](KLHL21)|2|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 242 | +|[KRTAP5-5](KRTAP5-5)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 243 | +|[LAMA5](LAMA5)|2|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 238 | 244 | |[LAPTM5](LAPTM5)|2, aSHM||[@hubschmannMutationalMechanismsShaping2021b]| |
| 239 | -|[LIN54](LIN54)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 240 | -|[LPP](LPP)|2, aSHM|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 241 | -|[LRP12](LRP12)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 242 | -|[LRRN3](LRRN3)|2|[@morinMutationalStructuralAnalysis2013]|[@sarkozyMutationalLandscapeGray2021a]| |
|
| 243 | -|[LYN](LYN)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 244 | -|[MAGT1](MAGT1)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 245 | -|[MALAT1](MALAT1)|2, aSHM|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 246 | -|[MAP2K1](MAP2K1)|2|[@shinBRAFV600EMAP2K12015]|[@louissaintPediatrictypeNodalFollicular2016a]| |
|
| 247 | -|[MAP4K4](MAP4K4)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 248 | -|[MARK1](MARK1)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 249 | -|[MCL1](MCL1)|2|[@reddyGeneticFunctionalDrivers2017]|[@paneaWholeGenomeLandscape2019; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 250 | -|[MECOM](MECOM)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 251 | -|[MET](MET)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 252 | -|[MIR142](MIR142)|2, aSHM|[@kwanhianMicroRNA142Mutated202012b]|[@grandeGenomewideDiscoverySomatic2019]| |
|
| 245 | +|[LIN54](LIN54)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 246 | +|[LPP](LPP)|2, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 247 | +|[LRP12](LRP12)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 248 | +|[LRRN3](LRRN3)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@sarkozyMutationalLandscapeGray2021a]| |
|
| 249 | +|[LYN](LYN)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 250 | +|[MAGT1](MAGT1)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 251 | +|[MALAT1](MALAT1)|2, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 252 | +|[MAP2K1](MAP2K1)|2|[Study Overview](papers/shinBRAFV600EMAP2K12015)[@shinBRAFV600EMAP2K12015]|[@louissaintPediatrictypeNodalFollicular2016a]| |
|
| 253 | +|[MAP4K4](MAP4K4)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 254 | +|[MARK1](MARK1)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 255 | +|[MCL1](MCL1)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@paneaWholeGenomeLandscape2019; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 256 | +|[MECOM](MECOM)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 257 | +|[MET](MET)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 258 | +|[MIR142](MIR142)|2, aSHM|[Study Overview](papers/kwanhianMicroRNA142Mutated202012b)[@kwanhianMicroRNA142Mutated202012b]|[@grandeGenomewideDiscoverySomatic2019]| |
|
| 253 | 259 | |[MIR155HG](MIR155HG)|2, aSHM||| |
| 254 | -|[MPDZ](MPDZ)|2|[@morinMutationalStructuralAnalysis2013]|[@reichelFlowSortingExome2015a]| |
|
| 255 | -|[MSH2](MSH2)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 256 | -|[MSH6](MSH6)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 257 | -|[MYB](MYB)|2|[@reddyGeneticFunctionalDrivers2017]|[@deschGenotypingCirculatingTumor2020]| |
|
| 258 | -|[MYBPC2](MYBPC2)|2|[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 260 | +|[MPDZ](MPDZ)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@reichelFlowSortingExome2015a]| |
|
| 261 | +|[MSH2](MSH2)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 262 | +|[MSH6](MSH6)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 263 | +|[MYB](MYB)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@deschGenotypingCirculatingTumor2020]| |
|
| 264 | +|[MYBPC2](MYBPC2)|2|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 259 | 265 | |[MYO1E](MYO1E)|2, aSHM||| |
| 260 | -|[MYOM2](MYOM2)|2|[@pasqualucciAnalysisCodingGenome2011]|| |
|
| 261 | -|[NR2F2](N2RF2)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 262 | -|[NANOG](NANOG)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 263 | -|[NAV1](NAV1)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 266 | +|[MYOM2](MYOM2)|2|[Study Overview](papers/pasqualucciAnalysisCodingGenome2011)[@pasqualucciAnalysisCodingGenome2011]|| |
|
| 267 | +|[N2RF2](N2RF2)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 268 | +|[NANOG](NANOG)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 269 | +|[NAV1](NAV1)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 264 | 270 | |[NCOA3](NCOA3)|2, aSHM||| |
| 265 | -|[NCOR1](NCOR1)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 271 | +|[NCOR1](NCOR1)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 266 | 272 | |[NCOR2](NCOR2)|2||[@schmitzBurkittLymphomaPathogenesis2012; @spinaGeneticsNodalMarginal2016b; @sarkozyMutationalLandscapeGray2021a]| |
| 267 | -|[NEAT1](NEAT1)|2, aSHM|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 268 | -|[NF1](NF1)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 273 | +|[NEAT1](NEAT1)|2, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 274 | +|[NF1](NF1)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 269 | 275 | |[NFKB1](NFKB1)|2||| |
| 270 | -|[NFKB2](NFKB2)|2|[@reddyGeneticFunctionalDrivers2017]|[@mottokIntegrativeGenomicAnalysis2019b]| |
|
| 276 | +|[NFKB2](NFKB2)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@mottokIntegrativeGenomicAnalysis2019b]| |
|
| 271 | 277 | |[NLRC5](NLRC5)|2||| |
| 272 | -|[NLRP5](NLRP5)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 273 | -|[NLRP8](NLRP8)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 274 | -|[ODZ3](ODZ3)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 275 | -|[P2RX5](P2RX5)|2, aSHM|[@morinMutationalStructuralAnalysis2013]|| |
|
| 276 | -|[PAPOLG](PAPOLG)|2|[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 277 | -|[PASK](PASK)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 278 | -|[PAX5](PAX5)|2, aSHM|[@pasqualucciHypermutationMultipleProtooncogenes2001a]|| |
|
| 278 | +|[NLRP5](NLRP5)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 279 | +|[NLRP8](NLRP8)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 280 | +|[ODZ3](ODZ3)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 281 | +|[OR6K3](OR6K3)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 282 | +|[P2RX5](P2RX5)|2, aSHM|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 283 | +|[PAPOLG](PAPOLG)|2|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 284 | +|[PASD1](PASD1)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 285 | +|[PASK](PASK)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 286 | +|[PAX5](PAX5)|2, aSHM|[Study Overview](papers/pasqualucciHypermutationMultipleProtooncogenes2001a)[@pasqualucciHypermutationMultipleProtooncogenes2001a]|| |
|
| 279 | 287 | |[PCBP1](PCBP1)|2||[@schmitzBurkittLymphomaPathogenesis2012]| |
| 280 | -|[PCDHB11](PCDHB11)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 281 | -|[PCLO](PCLO)|2|[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 282 | -|[PDE4DIP](PDE4DIP)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 283 | -|[PDS5B](PDS5B)|2|[@morinMutationalStructuralAnalysis2013]|[@hubschmannMutationalMechanismsShaping2021b]| |
|
| 284 | -|[PHF6](PHF6)|2|[@reddyGeneticFunctionalDrivers2017]|[@thomasGeneticSubgroupsInform2023]| |
|
| 285 | -|[PIK3CD](PIK3CD)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 286 | -|[PIK3R1](PIK3R1)|2|[@zhangGeneticHeterogeneityDiffuse2013]|[@paneaWholeGenomeLandscape2019]| |
|
| 287 | -|[PKD1](PKD1)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 288 | -|[PNPO](PNPO)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 289 | -|[POGZ](POGZ)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 288 | +|[PCDHB11](PCDHB11)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 289 | +|[PCDHB6](PCDHB6)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 290 | +|[PCLO](PCLO)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 291 | +|[PDE4DIP](PDE4DIP)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 292 | +|[PDGFC](PDGFC)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 293 | +|[PDS5B](PDS5B)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@hubschmannMutationalMechanismsShaping2021b]| |
|
| 294 | +|[PHF6](PHF6)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@thomasGeneticSubgroupsInform2023]| |
|
| 295 | +|[PIK3CD](PIK3CD)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 296 | +|[PIK3R1](PIK3R1)|2|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@paneaWholeGenomeLandscape2019]| |
|
| 297 | +|[PKD1](PKD1)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 298 | +|[PNPO](PNPO)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 299 | +|[POGZ](POGZ)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 290 | 300 | |[PPP1R9B](PPP1R9B)|2||| |
| 291 | -|[PRKCB](PRKCB)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 292 | -|[PRKDC](PRKDC)|2|[@schmitzGeneticsPathogenesisDiffuse2018a]|[@hubschmannMutationalMechanismsShaping2021b]| |
|
| 293 | -|[PRPS1](PRPS1)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 301 | +|[PRKCB](PRKCB)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 302 | +|[PRKDC](PRKDC)|2|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|[@hubschmannMutationalMechanismsShaping2021b]| |
|
| 303 | +|[PRPS1](PRPS1)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 294 | 304 | |[PTMA](PTMA)|2, aSHM||| |
| 295 | 305 | |[PTPN1](PTPN1)|2, aSHM||[@gunawardanaRecurrentSomaticMutations2014c]| |
| 296 | -|[PTPN23](PTPN23)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 297 | -|[PTPN6](PTPN6)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 298 | -|[PTPRK](PTPRK)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 299 | -|[RAC2](RAC2)|2|[@hubschmannMutationalMechanismsShaping2021b]|[@paneaWholeGenomeLandscape2019]| |
|
| 300 | -|[RAD9A](RAD9A)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 301 | -|[RARA](RARA)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 306 | +|[PTPN23](PTPN23)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 307 | +|[PTPN6](PTPN6)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 308 | +|[PTPRK](PTPRK)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 309 | +|[RAC2](RAC2)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@paneaWholeGenomeLandscape2019]| |
|
| 310 | +|[RAD9A](RAD9A)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 311 | +|[RARA](RARA)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 302 | 312 | |[RCC](RCC)|2, aSHM||| |
| 303 | -|[RFTN1](RFTN1)|2, aSHM|[@arthurGenomewideDiscoverySomatic2018]|[@dunsCharacterizationDLBCLPMBL2021b]| |
|
| 313 | +|[RFTN1](RFTN1)|2, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|[@dunsCharacterizationDLBCLPMBL2021b]| |
|
| 304 | 314 | |[RFXAP](RFXAP)|2||| |
| 305 | 315 | |[RHEX](RHEX)|2, aSHM||| |
| 306 | -|[RHOH](RHOH)|2, aSHM|[@pasqualucciHypermutationMultipleProtooncogenes2001a]|| |
|
| 316 | +|[RHOH](RHOH)|2, aSHM|[Study Overview](papers/pasqualucciHypermutationMultipleProtooncogenes2001a)[@pasqualucciHypermutationMultipleProtooncogenes2001a]|| |
|
| 307 | 317 | |[RUBCNL](RUBCNL)|2, aSHM||| |
| 308 | -|[RUNX1](RUNX1)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 309 | -|[SAMD9L](SAMD9L)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 310 | -|[SARM1](SARM1)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 318 | +|[RUNX1](RUNX1)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 319 | +|[S1PR1](S1PR1)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|[@pararajalingamCodingNoncodingDrivers2020]| |
|
| 320 | +|[SAMD9L](SAMD9L)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 321 | +|[SARM1](SARM1)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 311 | 322 | |[SEL1L3](SEL1L3)|2, aSHM||| |
| 312 | 323 | |[SEPTIN9](SEPTIN9)|2, aSHM||| |
| 313 | -|[SERPINA9](SERPINA9)|2, aSHM|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 314 | -|[SETD2](SETD2)|2|[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 315 | -|[SETD5](SETD5)|2|[@reddyGeneticFunctionalDrivers2017]|[@tiacciPervasiveMutationsJAKSTAT2018b]| |
|
| 316 | -|[SIAH2](SIAH2)|2|[@hubschmannMutationalMechanismsShaping2021b]|[@reichelFlowSortingExome2015a]| |
|
| 317 | -|[SLC34A2](SLC34A2)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 318 | -|[SMEK1](SMEK1)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 319 | -|[SRRM2](SRRM2)|2|[@morinMutationalStructuralAnalysis2013]|[@russler-germainMutationsAssociatedProgression2023b]| |
|
| 320 | -|[ST6GAL1](ST6GAL1)|2, aSHM|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 321 | -|[STAT5B](STAT5B)|2|[@zhangGeneticHeterogeneityDiffuse2013]|[@tiacciPervasiveMutationsJAKSTAT2018b]| |
|
| 322 | -|[SYK](SYK)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 323 | -|[SYPL1](SYPL1)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 324 | -|[TAP1](TAP1)|2|[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 325 | -|[TBC1D4](TBC1D4)|2, aSHM|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 324 | +|[SERPINA9](SERPINA9)|2, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 325 | +|[SETD2](SETD2)|2|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 326 | +|[SETD5](SETD5)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@tiacciPervasiveMutationsJAKSTAT2018b]| |
|
| 327 | +|[SIAH2](SIAH2)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@reichelFlowSortingExome2015a]| |
|
| 328 | +|[SLC34A2](SLC34A2)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 329 | +|[SLC38A8](SLC38A8)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 330 | +|[SLITRK6](SLITRK6)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 331 | +|[SMEK1](SMEK1)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 332 | +|[SRPX](SRPX)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 333 | +|[SRRM2](SRRM2)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|[@russler-germainMutationsAssociatedProgression2023b]| |
|
| 334 | +|[ST6GAL1](ST6GAL1)|2, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 335 | +|[STAT5B](STAT5B)|2|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@tiacciPervasiveMutationsJAKSTAT2018b]| |
|
| 336 | +|[SYK](SYK)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 337 | +|[SYN2](SYN2)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 338 | +|[SYPL1](SYPL1)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 339 | +|[TAP1](TAP1)|2|[Study Overview](papers/schmitzGeneticsPathogenesisDiffuse2018a)[@schmitzGeneticsPathogenesisDiffuse2018a]|| |
|
| 340 | +|[TBC1D4](TBC1D4)|2, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 326 | 341 | |[TCL1A](TCL1A)|2, aSHM||[@grandeGenomewideDiscoverySomatic2019]| |
| 327 | -|[TGFBR2](TGFBR2)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 328 | -|[TIPARP](TIPARP)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 329 | -|[TLR2](TLR2)|2|[@chapuyMolecularSubtypesDiffuse2018b]|[@beaLandscapeSomaticMutations2013]| |
|
| 330 | -|[TRAF3](TRAF3)|2|[@pasqualucciAnalysisCodingGenome2011]|[@rossiAlterationBIRC3Multiple2011a; @ottoGeneticLesionsTRAF32012a]| |
|
| 331 | -|[TRAF6](TRAF6)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 342 | +|[TGFBR2](TGFBR2)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 343 | +|[TIPARP](TIPARP)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 344 | +|[TLR2](TLR2)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|[@beaLandscapeSomaticMutations2013]| |
|
| 345 | +|[TMSL3](TMSL3)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 346 | +|[TNF](TNF)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 347 | +|[TRAF3](TRAF3)|2|[Study Overview](papers/pasqualucciAnalysisCodingGenome2011)[@pasqualucciAnalysisCodingGenome2011]|[@rossiAlterationBIRC3Multiple2011a; @ottoGeneticLesionsTRAF32012a]| |
|
| 348 | +|[TRAF6](TRAF6)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 332 | 349 | |[TRIP12](TRIP12)|2||| |
| 333 | 350 | |[UBE2J1](UBE2J1)|2, aSHM||| |
| 334 | -|[UBR5](UBR5)|2|[@zhangGeneticHeterogeneityDiffuse2013]|[@pararajalingamCodingNoncodingDrivers2020]| |
|
| 335 | -|[UNC5B](UNC5B)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 336 | -|[UNC5D](UNC5D)|2||| |
|
| 337 | -|[WAC](WAC)|2|[@reddyGeneticFunctionalDrivers2017]|[@rossiCodingGenomeSplenic2012c]| |
|
| 338 | -|[WDFY3](WDFY3)|2|[@morinMutationalStructuralAnalysis2013]|| |
|
| 339 | -|[WNK1](WNK1)|2|[@hubschmannMutationalMechanismsShaping2021b]|[@thomasGeneticSubgroupsInform2023; @jalladesExomeSequencingIdentifies2017]| |
|
| 340 | -|[YY1](YY1)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 341 | -|[ZBTB7A](ZBTB7A)|2|[@reddyGeneticFunctionalDrivers2017]|[@burkhardtClinicalRelevanceMolecular2022b]| |
|
| 342 | -|[ZCCHC7](ZCCHC7)|2, aSHM|[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 343 | -|[ZEB2](ZEB2)|2|[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 344 | -|[ZFAT](ZFAT)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 345 | -|[ZFX](ZFX)|2|[@reddyGeneticFunctionalDrivers2017]|| |
|
| 346 | -|[ZNF217](ZNF217)|2|[@hubschmannMutationalMechanismsShaping2021b]|[@reichelFlowSortingExome2015a]| |
|
| 347 | -|[ZNF423](ZNF423)|2|[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 351 | +|[UBR5](UBR5)|2|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|[@pararajalingamCodingNoncodingDrivers2020]| |
|
| 352 | +|[UNC5B](UNC5B)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 353 | +|[UNC5D](UNC5D)|2|[Study Overview](papers/lohrDiscoveryPrioritizationSomatic2012a)[@lohrDiscoveryPrioritizationSomatic2012a]|| |
|
| 354 | +|[WAC](WAC)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@rossiCodingGenomeSplenic2012c]| |
|
| 355 | +|[WDFY3](WDFY3)|2|[Study Overview](papers/morinMutationalStructuralAnalysis2013)[@morinMutationalStructuralAnalysis2013]|| |
|
| 356 | +|[WNK1](WNK1)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@jalladesExomeSequencingIdentifies2017; @thomasGeneticSubgroupsInform2023]| |
|
| 357 | +|[XBP1](XBP1)|2, aSHM||| |
|
| 358 | +|[YY1](YY1)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 359 | +|[ZBTB7A](ZBTB7A)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|[@burkhardtClinicalRelevanceMolecular2022b]| |
|
| 360 | +|[ZCCHC7](ZCCHC7)|2, aSHM|[Study Overview](papers/arthurGenomewideDiscoverySomatic2018)[@arthurGenomewideDiscoverySomatic2018]|| |
|
| 361 | +|[ZEB2](ZEB2)|2|[Study Overview](papers/zhangGeneticHeterogeneityDiffuse2013)[@zhangGeneticHeterogeneityDiffuse2013]|| |
|
| 362 | +|[ZFAT](ZFAT)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 363 | +|[ZFX](ZFX)|2|[Study Overview](papers/reddyGeneticFunctionalDrivers2017)[@reddyGeneticFunctionalDrivers2017]|| |
|
| 364 | +|[ZNF217](ZNF217)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@reichelFlowSortingExome2015a]| |
|
| 365 | +|[ZNF423](ZNF423)|2|[Study Overview](papers/chapuyMolecularSubtypesDiffuse2018b)[@chapuyMolecularSubtypesDiffuse2018b]|| |
|
| 348 | 366 | |
| 349 | 367 | |
| 350 | 368 | # References |
FL_genes.md
| ... | ... | @@ -16,71 +16,71 @@ link-citations: true |
| 16 | 16 | |Gene|Tier| First FL evidence | Other entities | |
| 17 | 17 | |:-:|:-:|:-|:-| |
| 18 | 18 | |[ACTB](ACTB)|1, aSHM||[@lohrDiscoveryPrioritizationSomatic2012a; @wienandGenomicAnalysesFlowsorted2019b]| |
| 19 | -|[ARID1A](ARID1A)|1|[@krysiakRecurrentSomaticMutations2017b]|[@loveGeneticLandscapeMutations2012; @rossiCodingGenomeSplenic2012c; @zhangGeneticHeterogeneityDiffuse2013; @wienandGenomicAnalysesFlowsorted2019b]| |
|
| 20 | -|[ATP6AP1](ATP6AP1)|1|[@okosunRecurrentMTORC1activatingRRAGC2016a]|| |
|
| 21 | -|[ATP6V1B2](ATP6V1B2)|1|[@okosunRecurrentMTORC1activatingRRAGC2016a]|| |
|
| 22 | -|[B2M](B2M)|1|[@morinFrequentMutationHistonemodifying2011]|[@pararajalingamCodingNoncodingDrivers2020; @reichelFlowSortingExome2015a]| |
|
| 23 | -|[BCL2](BCL2)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@burkhardtClinicalRelevanceMolecular2022b; @sarkozyMutationalLandscapeGray2021a; @tanakaFrequentIncidenceSomatic1992]| |
|
| 19 | +|[ARID1A](ARID1A)|1|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@zhangGeneticHeterogeneityDiffuse2013; @loveGeneticLandscapeMutations2012; @wienandGenomicAnalysesFlowsorted2019b; @rossiCodingGenomeSplenic2012c]| |
|
| 20 | +|[ATP6AP1](ATP6AP1)|1|[Study Overview](papers/okosunRecurrentMTORC1activatingRRAGC2016a)[@okosunRecurrentMTORC1activatingRRAGC2016a]|| |
|
| 21 | +|[ATP6V1B2](ATP6V1B2)|1|[Study Overview](papers/okosunRecurrentMTORC1activatingRRAGC2016a)[@okosunRecurrentMTORC1activatingRRAGC2016a]|| |
|
| 22 | +|[B2M](B2M)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@reichelFlowSortingExome2015a; @pararajalingamCodingNoncodingDrivers2020]| |
|
| 23 | +|[BCL2](BCL2)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@sarkozyMutationalLandscapeGray2021a; @burkhardtClinicalRelevanceMolecular2022b; @tanakaFrequentIncidenceSomatic1992]| |
|
| 24 | 24 | |[BCL6](BCL6)|1, aSHM||[@morinFrequentMutationHistonemodifying2011; @loveGeneticLandscapeMutations2012]| |
| 25 | -|[BCL7A](BCL7A)|1, aSHM|[@krysiakRecurrentSomaticMutations2017b]|[@arthurGenomewideDiscoverySomatic2018; @reichelFlowSortingExome2015a; @grandeGenomewideDiscoverySomatic2019]| |
|
| 25 | +|[BCL7A](BCL7A)|1, aSHM|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@grandeGenomewideDiscoverySomatic2019; @reichelFlowSortingExome2015a; @arthurGenomewideDiscoverySomatic2018]| |
|
| 26 | 26 | |[BIRC6](BIRC6)|1||[@reddyGeneticFunctionalDrivers2017; @sarkozyMutationalLandscapeGray2021a]| |
| 27 | -|[BTG1](BTG1)|1, aSHM||[@morinFrequentMutationHistonemodifying2011; @burkhardtClinicalRelevanceMolecular2022b; @sarkozyMutationalLandscapeGray2021a]| |
|
| 28 | -|[BTG2](BTG2)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@loveGeneticLandscapeMutations2012]| |
|
| 29 | -|[BTK](BTK)|1|[@krysiakRecurrentSomaticMutations2017b]|[@albuquerqueEnhancingKnowledgeDiscovery2017a]| |
|
| 30 | -|[CARD11](CARD11)|1|[@morinFrequentMutationHistonemodifying2011]|[@lenzOncogenicCARD11Mutations2008; @wuGeneticHeterogeneityPrimary2016; @paneaWholeGenomeLandscape2019; @yanBCRTLRSignaling2012a]| |
|
| 31 | -|[CCND3](CCND3)|1|[@morinFrequentMutationHistonemodifying2011]|[@richterRecurrentMutationID32012a; @jalladesExomeSequencingIdentifies2017; @deschGenotypingCirculatingTumor2020]| |
|
| 32 | -|[CD83](CD83)|1, aSHM|[@russler-germainMutationsAssociatedProgression2023b]|[@paneaWholeGenomeLandscape2019; @dunsCharacterizationDLBCLPMBL2021b; @morinMutationalStructuralAnalysis2013]| |
|
| 33 | -|[CREBBP](CREBBP)|1|[@pasqualucciInactivatingMutationsAcetyltransferase2011a]|[@parryWholeExomeSequencing2013; @dunsCharacterizationDLBCLPMBL2021b; @loveGeneticLandscapeMutations2012]| |
|
| 34 | -|[CTSS](CTSS)|1|[@barariaCathepsinAlterationsInduce2020c]|| |
|
| 35 | -|[DTX1](DTX1)|1, aSHM||[@schmitzGeneticsPathogenesisDiffuse2018a; @rossiCodingGenomeSplenic2012c; @gomezUltraDeepSequencingReveals2023; @paneaWholeGenomeLandscape2019]| |
|
| 36 | -|[EBF1](EBF1)|1, aSHM||[@thomasGeneticSubgroupsInform2023; @reichelFlowSortingExome2015a; @bohleRoleEarlyBcell2013]| |
|
| 37 | -|[EEF1A1](EEF1A1)|1|[@hubschmannMutationalMechanismsShaping2021b]|[@reichelFlowSortingExome2015a]| |
|
| 38 | -|[EP300](EP300)|1|[@pasqualucciInactivatingMutationsAcetyltransferase2011a]|[@rossiCodingGenomeSplenic2012c; @paneaWholeGenomeLandscape2019]| |
|
| 39 | -|[EZH2](EZH2)|1|[@morinSomaticMutationsAltering2010a]|[@mottokIntegrativeGenomicAnalysis2019b; @loveGeneticLandscapeMutations2012]| |
|
| 40 | -|[FAS](FAS)|1||[@spinaGeneticsNodalMarginal2016b; @schollMutationsRegionFAS2007]| |
|
| 41 | -|[FOXO1](FOXO1)|1|[@morinFrequentMutationHistonemodifying2011]|[@schmitzBurkittLymphomaPathogenesis2012; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 42 | -|[GNA13](GNA13)|1|[@morinFrequentMutationHistonemodifying2011]|[@reichelFlowSortingExome2015a; @loveGeneticLandscapeMutations2012]| |
|
| 27 | +|[BTG1](BTG1)|1, aSHM||[@burkhardtClinicalRelevanceMolecular2022b; @sarkozyMutationalLandscapeGray2021a; @morinFrequentMutationHistonemodifying2011]| |
|
| 28 | +|[BTG2](BTG2)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@loveGeneticLandscapeMutations2012]| |
|
| 29 | +|[BTK](BTK)|1|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@albuquerqueEnhancingKnowledgeDiscovery2017a]| |
|
| 30 | +|[CARD11](CARD11)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019; @lenzOncogenicCARD11Mutations2008; @yanBCRTLRSignaling2012a; @wuGeneticHeterogeneityPrimary2016]| |
|
| 31 | +|[CCND3](CCND3)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@deschGenotypingCirculatingTumor2020; @jalladesExomeSequencingIdentifies2017; @richterRecurrentMutationID32012a]| |
|
| 32 | +|[CD83](CD83)|1, aSHM|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|[@paneaWholeGenomeLandscape2019; @morinMutationalStructuralAnalysis2013; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 33 | +|[CREBBP](CREBBP)|1|[Study Overview](papers/pasqualucciInactivatingMutationsAcetyltransferase2011a)[@pasqualucciInactivatingMutationsAcetyltransferase2011a]|[@loveGeneticLandscapeMutations2012; @parryWholeExomeSequencing2013; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 34 | +|[CTSS](CTSS)|1|[Study Overview](papers/barariaCathepsinAlterationsInduce2020c)[@barariaCathepsinAlterationsInduce2020c]|| |
|
| 35 | +|[DTX1](DTX1)|1, aSHM||[@schmitzGeneticsPathogenesisDiffuse2018a; @rossiCodingGenomeSplenic2012c; @loveGeneticLandscapeMutations2012; @gomezUltraDeepSequencingReveals2023]| |
|
| 36 | +|[EBF1](EBF1)|1, aSHM||[@thomasGeneticSubgroupsInform2023; @bohleRoleEarlyBcell2013; @reichelFlowSortingExome2015a]| |
|
| 37 | +|[EEF1A1](EEF1A1)|1|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@reichelFlowSortingExome2015a]| |
|
| 38 | +|[EP300](EP300)|1|[Study Overview](papers/pasqualucciInactivatingMutationsAcetyltransferase2011a)[@pasqualucciInactivatingMutationsAcetyltransferase2011a]|[@paneaWholeGenomeLandscape2019; @rossiCodingGenomeSplenic2012c]| |
|
| 39 | +|[EZH2](EZH2)|1|[Study Overview](papers/morinSomaticMutationsAltering2010a)[@morinSomaticMutationsAltering2010a]|[@loveGeneticLandscapeMutations2012; @mottokIntegrativeGenomicAnalysis2019b]| |
|
| 40 | +|[FAS](FAS)|1||[@schollMutationsRegionFAS2007; @spinaGeneticsNodalMarginal2016b]| |
|
| 41 | +|[FOXO1](FOXO1)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@dunsCharacterizationDLBCLPMBL2021b; @schmitzBurkittLymphomaPathogenesis2012]| |
|
| 42 | +|[GNA13](GNA13)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@reichelFlowSortingExome2015a; @loveGeneticLandscapeMutations2012]| |
|
| 43 | 43 | |[GNAI2](GNAI2)|1||[@grandeGenomewideDiscoverySomatic2019; @morinMutationalStructuralAnalysis2013]| |
| 44 | -|[HIST1H1B](HIST1H1B)|1, aSHM|[@krysiakRecurrentSomaticMutations2017b]|[@chapuyMolecularSubtypesDiffuse2018b; @sarkozyMutationalLandscapeGray2021a]| |
|
| 45 | -|[HIST1H1C](HIST1H1C)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019]| |
|
| 46 | -|[HIST1H1D](HIST1H1D)|1, aSHM|[@krysiakRecurrentSomaticMutations2017b]|[@morinMutationalStructuralAnalysis2013; @jalladesExomeSequencingIdentifies2017]| |
|
| 47 | -|[HIST1H1E](HIST1H1E)|1, aSHM|[@krysiakRecurrentSomaticMutations2017b]|[@morinMutationalStructuralAnalysis2013; @reichelFlowSortingExome2015a; @grandeGenomewideDiscoverySomatic2019]| |
|
| 48 | -|[HIST1H2AC](HIST1H2AC)|1, aSHM|[@krysiakRecurrentSomaticMutations2017b]|[@morinMutationalStructuralAnalysis2013]| |
|
| 49 | -|[HIST1H2AG](HIST1H2AG)|1, aSHM|[@krysiakRecurrentSomaticMutations2017b]|[@morinMutationalStructuralAnalysis2013; @rossiCodingGenomeSplenic2012c; @paneaWholeGenomeLandscape2019]| |
|
| 50 | -|[HIST1H2AM](HIST1H2AM)|1, aSHM|[@krysiakRecurrentSomaticMutations2017b]|[@paneaWholeGenomeLandscape2019]| |
|
| 51 | -|[HIST1H2BC](HIST1H2BC)|1, aSHM|[@krysiakRecurrentSomaticMutations2017b]|[@mottokIntegrativeGenomicAnalysis2019b; @reddyGeneticFunctionalDrivers2017]| |
|
| 52 | -|[HIST1H2BD](HIST1H2BD)|1, aSHM|[@krysiakRecurrentSomaticMutations2017b]|| |
|
| 53 | -|[HIST1H2BG](HIST1H2BG)|1, aSHM|[@krysiakRecurrentSomaticMutations2017b]|| |
|
| 54 | -|[HIST1H3B](HIST1H3B)|1, aSHM||[@zhangGeneticHeterogeneityDiffuse2013; @reichelFlowSortingExome2015a]| |
|
| 55 | -|[HIST1H3G](HIST1H3G)|1, aSHM|[@krysiakRecurrentSomaticMutations2017b]|| |
|
| 56 | -|[HVCN1](HVCN1)|1|[@krysiakRecurrentSomaticMutations2017b]|| |
|
| 44 | +|[HIST1H1B](HIST1H1B)|1, aSHM|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@chapuyMolecularSubtypesDiffuse2018b; @sarkozyMutationalLandscapeGray2021a]| |
|
| 45 | +|[HIST1H1C](HIST1H1C)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019]| |
|
| 46 | +|[HIST1H1D](HIST1H1D)|1, aSHM|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@jalladesExomeSequencingIdentifies2017; @morinMutationalStructuralAnalysis2013]| |
|
| 47 | +|[HIST1H1E](HIST1H1E)|1, aSHM|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@reichelFlowSortingExome2015a; @grandeGenomewideDiscoverySomatic2019; @lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 48 | +|[HIST1H2AC](HIST1H2AC)|1, aSHM|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@morinMutationalStructuralAnalysis2013]| |
|
| 49 | +|[HIST1H2AG](HIST1H2AG)|1, aSHM|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@paneaWholeGenomeLandscape2019; @morinMutationalStructuralAnalysis2013; @rossiCodingGenomeSplenic2012c]| |
|
| 50 | +|[HIST1H2AM](HIST1H2AM)|1, aSHM|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@paneaWholeGenomeLandscape2019]| |
|
| 51 | +|[HIST1H2BC](HIST1H2BC)|1, aSHM|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@mottokIntegrativeGenomicAnalysis2019b; @lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 52 | +|[HIST1H2BD](HIST1H2BD)|1, aSHM|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|| |
|
| 53 | +|[HIST1H2BG](HIST1H2BG)|1, aSHM|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|| |
|
| 54 | +|[HIST1H3B](HIST1H3B)|1, aSHM||[@reichelFlowSortingExome2015a; @lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 55 | +|[HIST1H3G](HIST1H3G)|1, aSHM|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|| |
|
| 56 | +|[HVCN1](HVCN1)|1|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|| |
|
| 57 | 57 | |[IRF4](IRF4)|1, aSHM||[@mottokIntegrativeGenomicAnalysis2019b; @morinFrequentMutationHistonemodifying2011]| |
| 58 | -|[IRF8](IRF8)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@mottokIntegrativeGenomicAnalysis2019b; @paneaWholeGenomeLandscape2019]| |
|
| 58 | +|[IRF8](IRF8)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@mottokIntegrativeGenomicAnalysis2019b; @paneaWholeGenomeLandscape2019]| |
|
| 59 | 59 | |[ITPKB](ITPKB)|1, aSHM||[@reichelFlowSortingExome2015a; @schmitzGeneticsPathogenesisDiffuse2018a]| |
| 60 | -|[KLF2](KLF2)|1, aSHM||[@jalladesExomeSequencingIdentifies2017; @deschGenotypingCirculatingTumor2020; @pasqualucciAnalysisCodingGenome2011]| |
|
| 61 | -|[KLHL6](KLHL6)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@paneaWholeGenomeLandscape2019; @ganapathiGeneticLandscapeDural2016]| |
|
| 62 | -|[KMT2D](KMT2D)|1|[@morinFrequentMutationHistonemodifying2011]|[@grandeGenomewideDiscoverySomatic2019; @beaLandscapeSomaticMutations2013; @deschGenotypingCirculatingTumor2020; @rossiCodingGenomeSplenic2012c]| |
|
| 63 | -|[LTB](LTB)|1, aSHM||[@chapuyMolecularSubtypesDiffuse2018b; @deschGenotypingCirculatingTumor2020; @paneaWholeGenomeLandscape2019]| |
|
| 64 | -|[MAP2K1](MAP2K1)|1|[@louissaintPediatrictypeNodalFollicular2016a]|[@shinBRAFV600EMAP2K12015]| |
|
| 65 | -|[MEF2B](MEF2B)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@beaLandscapeSomaticMutations2013]| |
|
| 60 | +|[KLF2](KLF2)|1, aSHM||[@pasqualucciAnalysisCodingGenome2011; @jalladesExomeSequencingIdentifies2017; @deschGenotypingCirculatingTumor2020]| |
|
| 61 | +|[KLHL6](KLHL6)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@ganapathiGeneticLandscapeDural2016; @paneaWholeGenomeLandscape2019]| |
|
| 62 | +|[KMT2D](KMT2D)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@rossiCodingGenomeSplenic2012c; @deschGenotypingCirculatingTumor2020; @grandeGenomewideDiscoverySomatic2019; @beaLandscapeSomaticMutations2013]| |
|
| 63 | +|[LTB](LTB)|1, aSHM||[@paneaWholeGenomeLandscape2019; @deschGenotypingCirculatingTumor2020; @chapuyMolecularSubtypesDiffuse2018b]| |
|
| 64 | +|[MAP2K1](MAP2K1)|1|[Study Overview](papers/louissaintPediatrictypeNodalFollicular2016a)[@louissaintPediatrictypeNodalFollicular2016a]|[@shinBRAFV600EMAP2K12015]| |
|
| 65 | +|[MEF2B](MEF2B)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@beaLandscapeSomaticMutations2013]| |
|
| 66 | 66 | |[MEF2C](MEF2C)|1, aSHM||[@arthurGenomewideDiscoverySomatic2018]| |
| 67 | 67 | |[PCLO](PCLO)|1||[@lohrDiscoveryPrioritizationSomatic2012a]| |
| 68 | -|[PIM1](PIM1)|1, aSHM||[@dunsCharacterizationDLBCLPMBL2021b; @burkhardtClinicalRelevanceMolecular2022b; @pasqualucciHypermutationMultipleProtooncogenes2001a]| |
|
| 69 | -|[POU2AF1](POU2AF1)|1|[@krysiakRecurrentSomaticMutations2017b]|| |
|
| 70 | -|[POU2F2](POU2F2)|1|[@krysiakRecurrentSomaticMutations2017b]|[@zhangGeneticHeterogeneityDiffuse2013]| |
|
| 68 | +|[PIM1](PIM1)|1, aSHM||[@burkhardtClinicalRelevanceMolecular2022b; @pasqualucciHypermutationMultipleProtooncogenes2001a; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 69 | +|[POU2AF1](POU2AF1)|1|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|| |
|
| 70 | +|[POU2F2](POU2F2)|1|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 71 | 71 | |[PTPRD](PTPRD)|1||[@spinaGeneticsNodalMarginal2016b]| |
| 72 | 72 | |[RRAGC](RRAGC)|1||[@okosunRecurrentMTORC1activatingRRAGC2016a]| |
| 73 | 73 | |[S1PR2](S1PR2)|1, aSHM||[@morinFrequentMutationHistonemodifying2011; @muppidiLossSignalingGa132014b]| |
| 74 | -|[SGK1](SGK1)|1, aSHM|[@morinFrequentMutationHistonemodifying2011]|[@dunsCharacterizationDLBCLPMBL2021b]| |
|
| 75 | -|[SMARCA4](SMARCA4)|1|[@krysiakRecurrentSomaticMutations2017b]|[@richterRecurrentMutationID32012a; @zhangGeneticHeterogeneityDiffuse2013; @nadeuGenomicEpigenomicInsights2020b]| |
|
| 76 | -|[SOCS1](SOCS1)|1, aSHM||[@wenigerMutationsTumorSuppressor2006a; @morinFrequentMutationHistonemodifying2011]| |
|
| 77 | -|[STAT6](STAT6)|1|[@yildizActivatingSTAT6Mutations2015c]|[@ritzRecurrentMutationsSTAT62009a]| |
|
| 78 | -|[TBL1XR1](TBL1XR1)|1||[@rossiCodingGenomeSplenic2012c; @mareschalWholeExomeSequencing2016]| |
|
| 74 | +|[SGK1](SGK1)|1, aSHM|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@dunsCharacterizationDLBCLPMBL2021b]| |
|
| 75 | +|[SMARCA4](SMARCA4)|1|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@richterRecurrentMutationID32012a; @lohrDiscoveryPrioritizationSomatic2012a; @nadeuGenomicEpigenomicInsights2020b]| |
|
| 76 | +|[SOCS1](SOCS1)|1, aSHM||[@morinFrequentMutationHistonemodifying2011; @wenigerMutationsTumorSuppressor2006a]| |
|
| 77 | +|[STAT6](STAT6)|1|[Study Overview](papers/yildizActivatingSTAT6Mutations2015c)[@yildizActivatingSTAT6Mutations2015c]|[@ritzRecurrentMutationsSTAT62009a]| |
|
| 78 | +|[TBL1XR1](TBL1XR1)|1||[@rossiCodingGenomeSplenic2012c; @lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 79 | 79 | |[TMSB4X](TMSB4X)|1, aSHM||[@albuquerqueEnhancingKnowledgeDiscovery2017a]| |
| 80 | -|[TNFAIP3](TNFAIP3)|1||[@rossiAlterationBIRC3Multiple2011a; @compagnoMutationsMultipleGenes2009a; @schmitzTNFAIP3A20Tumor2009a]| |
|
| 81 | -|[TNFRSF14](TNFRSF14)|1|[@cheungAcquiredTNFRSF14Mutations2010a]|[@spinaGeneticsNodalMarginal2016b]| |
|
| 82 | -|[TP53](TP53)|1|[@morinFrequentMutationHistonemodifying2011]|[@wildaInactivationARFMDM2p53Pathway2004; @rossiCodingGenomeSplenic2012c; @beaLandscapeSomaticMutations2013; @tiacciPervasiveMutationsJAKSTAT2018b]| |
|
| 83 | -|[VMA21](VMA21)|1|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 80 | +|[TNFAIP3](TNFAIP3)|1||[@schmitzTNFAIP3A20Tumor2009a; @rossiAlterationBIRC3Multiple2011a; @compagnoMutationsMultipleGenes2009a]| |
|
| 81 | +|[TNFRSF14](TNFRSF14)|1|[Study Overview](papers/cheungAcquiredTNFRSF14Mutations2010a)[@cheungAcquiredTNFRSF14Mutations2010a]|[@spinaGeneticsNodalMarginal2016b; @morinFrequentMutationHistonemodifying2011]| |
|
| 82 | +|[TP53](TP53)|1|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|[@rossiCodingGenomeSplenic2012c; @tiacciPervasiveMutationsJAKSTAT2018b; @wildaInactivationARFMDM2p53Pathway2004; @beaLandscapeSomaticMutations2013; @lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 83 | +|[VMA21](VMA21)|1|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 84 | 84 | |
| 85 | 85 | ## Tier 2 FL genes |
| 86 | 86 | |
| ... | ... | @@ -88,56 +88,56 @@ link-citations: true |
| 88 | 88 | |
| 89 | 89 | |Gene|Tier| First FL evidence | Other entities | |
| 90 | 90 | |:-:|:-:|:-|:-| |
| 91 | -|[ABL2](ABL2)|2|[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 92 | -|[ACTG1](ACTG1)|2, aSHM|[@hubschmannMutationalMechanismsShaping2021b]|[@spinaGeneticsNodalMarginal2016b; @deschGenotypingCirculatingTumor2020]| |
|
| 93 | -|[ATP6V1A](ATP6V1A)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 94 | -|[BCL10](BCL10)|2|[@russler-germainMutationsAssociatedProgression2023b]|[@morinFrequentMutationHistonemodifying2011; @spinaGeneticsNodalMarginal2016b]| |
|
| 95 | -|[CDC42BPB](CDC42BPB)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 96 | -|[CD70](CD70)|2|[@russler-germainMutationsAssociatedProgression2023b]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 91 | +|[ABL2](ABL2)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 92 | +|[ACTG1](ACTG1)|2, aSHM|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@deschGenotypingCirculatingTumor2020; @spinaGeneticsNodalMarginal2016b]| |
|
| 93 | +|[ATP6V1A](ATP6V1A)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 94 | +|[BCL10](BCL10)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|[@morinFrequentMutationHistonemodifying2011; @spinaGeneticsNodalMarginal2016b]| |
|
| 95 | +|[CD70](CD70)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 97 | 96 | |[CD79B](CD79B)|2||[@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]| |
| 98 | -|[CILP](CILP)|2|[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 99 | -|[CPNE8](CPNE8)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 100 | -|[CXCR4](CXCR4)|2, aSHM|[@krysiakRecurrentSomaticMutations2017b]|[@paneaWholeGenomeLandscape2019; @khodabakhshiRecurrentTargetsAberrant2012]| |
|
| 101 | -|[CYP2A6](CYP2A6)|2|[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 97 | +|[CDC42BPB](CDC42BPB)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@spinaGeneticsNodalMarginal2016b]| |
|
| 98 | +|[CILP](CILP)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 99 | +|[CPNE8](CPNE8)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 100 | +|[CXCR4](CXCR4)|2, aSHM|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@khodabakhshiRecurrentTargetsAberrant2012; @paneaWholeGenomeLandscape2019]| |
|
| 101 | +|[CYP2A6](CYP2A6)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 102 | 102 | |[DDX3X](DDX3X)|2||[@schmitzBurkittLymphomaPathogenesis2012; @schmitzGeneticsPathogenesisDiffuse2018a; @mottokIntegrativeGenomicAnalysis2019b]| |
| 103 | -|[DHX15](DHX15)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 104 | -|[DUSP2](DUSP2)|2, aSHM||[@morinMutationalStructuralAnalysis2013; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 105 | -|[EGR1](EGR1)|2|[@krysiakRecurrentSomaticMutations2017b]|[@reichelFlowSortingExome2015a; @rossiCodingGenomeSplenic2012c]| |
|
| 106 | -|[FZR1](FZR1)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 107 | -|[GBP7](GBP7)|2|[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 108 | -|[GRM6](GRM6)|2|[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 109 | -|[HIST1H2BM](HIST1H2BM)|2, aSHM|[@krysiakRecurrentSomaticMutations2017b]|| |
|
| 110 | -|[HIST1H3I](HIST1H3I)|2, aSHM|[@krysiakRecurrentSomaticMutations2017b]|[@paneaWholeGenomeLandscape2019]| |
|
| 111 | -|[HLA-B](HLA-B)|2||[@wienandGenomicAnalysesFlowsorted2019b]| |
|
| 103 | +|[DHX15](DHX15)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 104 | +|[DUSP2](DUSP2)|2, aSHM||[@dunsCharacterizationDLBCLPMBL2021b; @lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 105 | +|[EGR1](EGR1)|2|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@rossiCodingGenomeSplenic2012c; @reichelFlowSortingExome2015a]| |
|
| 106 | +|[FZR1](FZR1)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 107 | +|[GBP7](GBP7)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 108 | +|[GRM6](GRM6)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 109 | +|[HIST1H2BM](HIST1H2BM)|2, aSHM|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|| |
|
| 110 | +|[HIST1H3I](HIST1H3I)|2, aSHM|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@paneaWholeGenomeLandscape2019]| |
|
| 111 | +|[HLA-B](HLA-B)|2||[@wienandGenomicAnalysesFlowsorted2019b; @lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 112 | 112 | |[HNRNPD](HNRNPD)|2||| |
| 113 | -|[IGLL5](IGLL5)|2, aSHM|[@russler-germainMutationsAssociatedProgression2023b]|[@deschGenotypingCirculatingTumor2020; @paneaWholeGenomeLandscape2019]| |
|
| 114 | -|[JUP](JUP)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 115 | -|[KIR3DL1](KIR3DL1)|2|[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 116 | -|[LAPTM5](LAPTM5)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 117 | -|[MAGEC1](MAGEC1)|2|[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 118 | -|[MAP7D1](MAP7D1)|2|[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 119 | -|[MGEA5](MGEA5)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 120 | -|[MKI67](MKI67)|2|[@russler-germainMutationsAssociatedProgression2023b]|[@schmitzBurkittLymphomaPathogenesis2012]| |
|
| 121 | -|[MYC](MYC)|2, aSHM||[@johnstonCmycHypermutationBurkitt1992; @jalladesExomeSequencingIdentifies2017; @dunsCharacterizationDLBCLPMBL2021b; @pasqualucciHypermutationMultipleProtooncogenes2001a]| |
|
| 122 | -|[MYCBP2](MYCBP2)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 123 | -|[MYD88](MYD88)|2||[@ngoOncogenicallyActiveMYD882011a; @yanBCRTLRSignaling2012a]| |
|
| 124 | -|[NFKBIA](NFKBIA)|2|[@russler-germainMutationsAssociatedProgression2023b]|[@wienandGenomicAnalysesFlowsorted2019b; @lakeMutationsNFKBIAEncoding2009]| |
|
| 125 | -|[OR8H2](OR8H2)|2|[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 126 | -|[P2RY8](P2RY8)|2||[@muppidiLossSignalingGa132014b; @lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 127 | -|[PDS5B](PDS5B)|2|[@hubschmannMutationalMechanismsShaping2021b]|[@morinMutationalStructuralAnalysis2013]| |
|
| 128 | -|[PPP4C](PPP4C)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 129 | -|[PRKDC](PRKDC)|2|[@hubschmannMutationalMechanismsShaping2021b]|[@schmitzGeneticsPathogenesisDiffuse2018a]| |
|
| 130 | -|[PZP](PZP)|2|[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 131 | -|[RBM6](RBM6)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 132 | -|[SESN1](SESN1)|2|[@oricchioGeneticEpigeneticInactivation2017b]|| |
|
| 133 | -|[SHROOM3](SHROOM3)|2|[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 134 | -|[SRRM2](SRRM2)|2|[@russler-germainMutationsAssociatedProgression2023b]|[@morinMutationalStructuralAnalysis2013]| |
|
| 135 | -|[STAB2](STAB2)|2|[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 136 | -|[TMEM30A](TMEM30A)|2|[@morinFrequentMutationHistonemodifying2011]|| |
|
| 137 | -|[TPP1](TPP1)|2|[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 138 | -|[XIRP2](XIRP2)|2|[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 113 | +|[IGLL5](IGLL5)|2, aSHM|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|[@paneaWholeGenomeLandscape2019; @deschGenotypingCirculatingTumor2020]| |
|
| 114 | +|[JUP](JUP)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 115 | +|[KIR3DL1](KIR3DL1)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 116 | +|[LAPTM5](LAPTM5)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 117 | +|[MAGEC1](MAGEC1)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 118 | +|[MAP7D1](MAP7D1)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 119 | +|[MGEA5](MGEA5)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 120 | +|[MKI67](MKI67)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|[@schmitzBurkittLymphomaPathogenesis2012]| |
|
| 121 | +|[MYC](MYC)|2, aSHM||[@jalladesExomeSequencingIdentifies2017; @dunsCharacterizationDLBCLPMBL2021b; @pasqualucciHypermutationMultipleProtooncogenes2001a; @johnstonCmycHypermutationBurkitt1992]| |
|
| 122 | +|[MYCBP2](MYCBP2)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 123 | +|[MYD88](MYD88)|2||[@yanBCRTLRSignaling2012a; @ngoOncogenicallyActiveMYD882011a]| |
|
| 124 | +|[NFKBIA](NFKBIA)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|[@lakeMutationsNFKBIAEncoding2009; @wienandGenomicAnalysesFlowsorted2019b]| |
|
| 125 | +|[OR8H2](OR8H2)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 126 | +|[P2RY8](P2RY8)|2||[@lohrDiscoveryPrioritizationSomatic2012a; @muppidiLossSignalingGa132014b]| |
|
| 127 | +|[PDS5B](PDS5B)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@morinMutationalStructuralAnalysis2013]| |
|
| 128 | +|[PPP4C](PPP4C)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 129 | +|[PRKDC](PRKDC)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|[@schmitzGeneticsPathogenesisDiffuse2018a]| |
|
| 130 | +|[PZP](PZP)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 131 | +|[RBM6](RBM6)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 132 | +|[SESN1](SESN1)|2|[Study Overview](papers/oricchioGeneticEpigeneticInactivation2017b)[@oricchioGeneticEpigeneticInactivation2017b]|| |
|
| 133 | +|[SHROOM3](SHROOM3)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 134 | +|[SRRM2](SRRM2)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|[@morinMutationalStructuralAnalysis2013]| |
|
| 135 | +|[STAB2](STAB2)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 136 | +|[TMEM30A](TMEM30A)|2|[Study Overview](papers/morinFrequentMutationHistonemodifying2011)[@morinFrequentMutationHistonemodifying2011]|| |
|
| 137 | +|[TPP1](TPP1)|2|[Study Overview](papers/hubschmannMutationalMechanismsShaping2021b)[@hubschmannMutationalMechanismsShaping2021b]|| |
|
| 138 | +|[XIRP2](XIRP2)|2|[Study Overview](papers/russler-germainMutationsAssociatedProgression2023b)[@russler-germainMutationsAssociatedProgression2023b]|| |
|
| 139 | 139 | |[ZC3H12A](ZC3H12A)|2||[@arthurGenomewideDiscoverySomatic2018]| |
| 140 | -|[ZNF608](ZNF608)|2|[@krysiakRecurrentSomaticMutations2017b]|[@zhangGeneticHeterogeneityDiffuse2013]| |
|
| 140 | +|[ZNF608](ZNF608)|2|[Study Overview](papers/krysiakRecurrentSomaticMutations2017b)[@krysiakRecurrentSomaticMutations2017b]|[@zhangGeneticHeterogeneityDiffuse2013]| |
|
| 141 | 141 | |
| 142 | 142 | |
| 143 | 143 | # References |
MCL_genes.md
| ... | ... | @@ -7,34 +7,7 @@ link-citations: true |
| 7 | 7 | |
| 8 | 8 | ## Origins of MCL genes |
| 9 | 9 | |
| 10 | -```mermaid |
|
| 11 | ---- |
|
| 12 | -config: |
|
| 13 | - sankey: |
|
| 14 | - showValues: false |
|
| 15 | - linkColor: target |
|
| 16 | - width: 800 |
|
| 17 | - height: 500 |
|
| 18 | - nodeAlignment: right |
|
| 19 | ---- |
|
| 20 | -sankey-beta |
|
| 21 | -Zhang 2014, MCL Tier 1, 2 |
|
| 22 | -Zhang 2014, MCL Tier 2, 26 |
|
| 23 | -Nadeu 2020, MCL Tier 1, 3 |
|
| 24 | -Nadeu 2020, MCL Tier 2, 2 |
|
| 25 | -Pararajalingam 2020, MCL Tier 1, 6 |
|
| 26 | -Pararajalingam 2020, MCL Tier 2, 1 |
|
| 27 | -Bea 2013, MCL Tier 1, 11 |
|
| 28 | -Bea 2013, MCL Tier 2, 16 |
|
| 29 | -MCL, exome, 28 |
|
| 30 | -exome, Zhang 2014, 28 |
|
| 31 | -MCL, WGS/exome, 7 |
|
| 32 | -WGS/exome, Pararajalingam 2020, 7 |
|
| 33 | -MCL, WGS, 5 |
|
| 34 | -WGS, Nadeu 2020, 5 |
|
| 35 | -MCL, WGS/exome, 27 |
|
| 36 | -WGS/exome, Bea 2013, 27 |
|
| 37 | -``` |
|
| 10 | + |
|
| 38 | 11 | |
| 39 | 12 | ## Tier 1 MCL genes |
| 40 | 13 | |
| ... | ... | @@ -42,29 +15,29 @@ WGS/exome, Bea 2013, 27 |
| 42 | 15 | |
| 43 | 16 | |Gene|Tier| First MCL evidence | Other entities | |
| 44 | 17 | |:-:|:-:|:-|:-| |
| 45 | -|[ATM](ATM)|1|[@beaLandscapeSomaticMutations2013]|[@reddyGeneticFunctionalDrivers2017; @braggioGenomicAnalysisMarginal2012]| |
|
| 46 | -|[BIRC3](BIRC3)|1|[@beaLandscapeSomaticMutations2013]|[@arthurGenomewideDiscoverySomatic2018; @rossiAlterationBIRC3Multiple2011a; @dunsCharacterizationDLBCLPMBL2021b]| |
|
| 47 | -|[CARD11](CARD11)|1|[@wuGeneticHeterogeneityPrimary2016]|[@paneaWholeGenomeLandscape2019; @morinFrequentMutationHistonemodifying2011; @lenzOncogenicCARD11Mutations2008; @yanBCRTLRSignaling2012a]| |
|
| 48 | -|[CCND1](CCND1)|1, aSHM|[@beaLandscapeSomaticMutations2013]|| |
|
| 49 | -|[DAZAP1](DAZAP1)|1|[@pararajalingamCodingNoncodingDrivers2020]|| |
|
| 50 | -|[EWSR1](EWSR1)|1|[@pararajalingamCodingNoncodingDrivers2020]|| |
|
| 51 | -|[HNRNPH1](HNRNPH1)|1, noncoding|[@pararajalingamCodingNoncodingDrivers2020]|| |
|
| 52 | -|[KMT2D](KMT2D)|1|[@beaLandscapeSomaticMutations2013]|[@rossiCodingGenomeSplenic2012c; @deschGenotypingCirculatingTumor2020; @morinFrequentMutationHistonemodifying2011; @grandeGenomewideDiscoverySomatic2019]| |
|
| 53 | -|[MEF2B](MEF2B)|1|[@beaLandscapeSomaticMutations2013]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 54 | -|[NFKBIE](NFKBIE)|1|[@pararajalingamCodingNoncodingDrivers2020]|[@morinGeneticLandscapesRelapsed2016; @mansouriFrequentNFKBIEDeletions2016]| |
|
| 55 | -|[NOTCH1](NOTCH1)|1|[@beaLandscapeSomaticMutations2013]|[@rossiCodingGenomeSplenic2012c; @pasqualucciAnalysisCodingGenome2011; @loveGeneticLandscapeMutations2012]| |
|
| 56 | -|[NOTCH2](NOTCH2)|1|[@beaLandscapeSomaticMutations2013]|[@rossiCodingGenomeSplenic2012c; @troenNOTCH2MutationsMarginal2008; @paneaWholeGenomeLandscape2019]| |
|
| 57 | -|[NSD2](NSD2)|1|[@beaLandscapeSomaticMutations2013]|| |
|
| 58 | -|[POT1](POT1)|1|[@zhangGenomicLandscapeMantle2014]|| |
|
| 59 | -|[RB1](RB1)|1|[@zhangGenomicLandscapeMantle2014]|[@morinMutationalStructuralAnalysis2013]| |
|
| 60 | -|[S1PR1](S1PR1)|1|[@pararajalingamCodingNoncodingDrivers2020]|| |
|
| 61 | -|[SMARCA4](SMARCA4)|1|[@nadeuGenomicEpigenomicInsights2020b]|[@krysiakRecurrentSomaticMutations2017b; @zhangGeneticHeterogeneityDiffuse2013; @richterRecurrentMutationID32012a]| |
|
| 62 | -|[SP140](SP140)|1|[@beaLandscapeSomaticMutations2013]|| |
|
| 63 | -|[SYNE1](SYNE1)|1|[@nadeuGenomicEpigenomicInsights2020b]|| |
|
| 64 | -|[TERT](TERT)|1, noncoding|[@nadeuGenomicEpigenomicInsights2020b]|| |
|
| 65 | -|[TLR2](TLR2)|1|[@beaLandscapeSomaticMutations2013]|[@chapuyMolecularSubtypesDiffuse2018b]| |
|
| 66 | -|[TP53](TP53)|1|[@beaLandscapeSomaticMutations2013]|[@morinFrequentMutationHistonemodifying2011; @tiacciPervasiveMutationsJAKSTAT2018b; @rossiCodingGenomeSplenic2012c; @wildaInactivationARFMDM2p53Pathway2004]| |
|
| 67 | -|[UBR5](UBR5)|1|[@pararajalingamCodingNoncodingDrivers2020]|[@zhangGeneticHeterogeneityDiffuse2013]| |
|
| 18 | +|[ATM](ATM)|1|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|[@reddyGeneticFunctionalDrivers2017; @braggioGenomicAnalysisMarginal2012]| |
|
| 19 | +|[BIRC3](BIRC3)|1|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|[@dunsCharacterizationDLBCLPMBL2021b; @arthurGenomewideDiscoverySomatic2018; @rossiAlterationBIRC3Multiple2011a]| |
|
| 20 | +|[CARD11](CARD11)|1|[Study Overview](papers/wuGeneticHeterogeneityPrimary2016)[@wuGeneticHeterogeneityPrimary2016]|[@morinFrequentMutationHistonemodifying2011; @lenzOncogenicCARD11Mutations2008; @paneaWholeGenomeLandscape2019; @yanBCRTLRSignaling2012a]| |
|
| 21 | +|[CCND1](CCND1)|1, aSHM|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 22 | +|[DAZAP1](DAZAP1)|1|[Study Overview](papers/pararajalingamCodingNoncodingDrivers2020)[@pararajalingamCodingNoncodingDrivers2020]|| |
|
| 23 | +|[EWSR1](EWSR1)|1|[Study Overview](papers/pararajalingamCodingNoncodingDrivers2020)[@pararajalingamCodingNoncodingDrivers2020]|| |
|
| 24 | +|[HNRNPH1](HNRNPH1)|1, noncoding|[Study Overview](papers/pararajalingamCodingNoncodingDrivers2020)[@pararajalingamCodingNoncodingDrivers2020]|| |
|
| 25 | +|[KMT2D](KMT2D)|1|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|[@grandeGenomewideDiscoverySomatic2019; @deschGenotypingCirculatingTumor2020; @rossiCodingGenomeSplenic2012c; @morinFrequentMutationHistonemodifying2011]| |
|
| 26 | +|[MEF2B](MEF2B)|1|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 27 | +|[NFKBIE](NFKBIE)|1|[Study Overview](papers/pararajalingamCodingNoncodingDrivers2020)[@pararajalingamCodingNoncodingDrivers2020]|[@morinGeneticLandscapesRelapsed2016; @mansouriFrequentNFKBIEDeletions2016]| |
|
| 28 | +|[NOTCH1](NOTCH1)|1|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|[@pasqualucciAnalysisCodingGenome2011; @rossiCodingGenomeSplenic2012c; @loveGeneticLandscapeMutations2012]| |
|
| 29 | +|[NOTCH2](NOTCH2)|1|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|[@troenNOTCH2MutationsMarginal2008; @rossiCodingGenomeSplenic2012c; @paneaWholeGenomeLandscape2019]| |
|
| 30 | +|[NSD2](NSD2)|1|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 31 | +|[POT1](POT1)|1|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 32 | +|[RB1](RB1)|1|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|[@morinMutationalStructuralAnalysis2013]| |
|
| 33 | +|[S1PR1](S1PR1)|1|[Study Overview](papers/pararajalingamCodingNoncodingDrivers2020)[@pararajalingamCodingNoncodingDrivers2020]|[@lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 34 | +|[SMARCA4](SMARCA4)|1|[Study Overview](papers/nadeuGenomicEpigenomicInsights2020b)[@nadeuGenomicEpigenomicInsights2020b]|[@krysiakRecurrentSomaticMutations2017b; @lohrDiscoveryPrioritizationSomatic2012a; @richterRecurrentMutationID32012a]| |
|
| 35 | +|[SP140](SP140)|1|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 36 | +|[SYNE1](SYNE1)|1|[Study Overview](papers/nadeuGenomicEpigenomicInsights2020b)[@nadeuGenomicEpigenomicInsights2020b]|| |
|
| 37 | +|[TERT](TERT)|1, noncoding|[Study Overview](papers/nadeuGenomicEpigenomicInsights2020b)[@nadeuGenomicEpigenomicInsights2020b]|| |
|
| 38 | +|[TLR2](TLR2)|1|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|[@chapuyMolecularSubtypesDiffuse2018b]| |
|
| 39 | +|[TP53](TP53)|1|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|[@wildaInactivationARFMDM2p53Pathway2004; @tiacciPervasiveMutationsJAKSTAT2018b; @lohrDiscoveryPrioritizationSomatic2012a; @rossiCodingGenomeSplenic2012c; @morinFrequentMutationHistonemodifying2011]| |
|
| 40 | +|[UBR5](UBR5)|1|[Study Overview](papers/pararajalingamCodingNoncodingDrivers2020)[@pararajalingamCodingNoncodingDrivers2020]|[@zhangGeneticHeterogeneityDiffuse2013]| |
|
| 68 | 41 | |
| 69 | 42 | ## Tier 2 MCL genes |
| 70 | 43 | |
| ... | ... | @@ -72,52 +45,52 @@ WGS/exome, Bea 2013, 27 |
| 72 | 45 | |
| 73 | 46 | |Gene|Tier| First MCL evidence | Other entities | |
| 74 | 47 | |:-:|:-:|:-|:-| |
| 75 | -|[ABCA3](ABCA3)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 76 | -|[ABCC9](ABCC9)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 77 | -|[ANK2](ANK2)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 48 | +|[ABCA3](ABCA3)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 49 | +|[ABCC9](ABCC9)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 50 | +|[ANK2](ANK2)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 78 | 51 | |[ARID1B](ARID1B)|2||[@reddyGeneticFunctionalDrivers2017]| |
| 79 | -|[ATP11C](ATP11C)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 80 | -|[B2M](B2M)|2|[@pararajalingamCodingNoncodingDrivers2020]|[@morinFrequentMutationHistonemodifying2011; @reichelFlowSortingExome2015a]| |
|
| 81 | -|[BCOR](BCOR)|2|[@nadeuGenomicEpigenomicInsights2020b]|[@jalladesExomeSequencingIdentifies2017]| |
|
| 82 | -|[CDH8](CDH8)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 83 | -|[CHMP4C](CHMP4C)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 84 | -|[COL11A1](COL11A1)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 85 | -|[COL16A1](COL16A1)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 86 | -|[CRYBG3](CRYBG3)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 87 | -|[CTNNA2](CTNNA2)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 88 | -|[DCP1B](DCP1B)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 89 | -|[DHDH](DHDH)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 90 | -|[DLC1](DLC1)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 91 | -|[DLGAP2](DLGAP2)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 92 | -|[DNAJC6](DNAJC6)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 93 | -|[EIF2AK4](EIF2AK4)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 94 | -|[ESX1](ESX1)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 95 | -|[FAT4](FAT4)|2|[@zhangGenomicLandscapeMantle2014]|[@parryWholeExomeSequencing2013; @morinMutationalStructuralAnalysis2013]| |
|
| 96 | -|[GRIN2A](GRIN2A)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 97 | -|[HEPH](HEPH)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 98 | -|[KCNC2](KCNC2)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 99 | -|[KIAA1671](KIAA1671)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 100 | -|[KMT2C](KMT2C)|2|[@zhangGenomicLandscapeMantle2014]|[@zhouSporadicEndemicBurkitt2019; @zhangGeneticHeterogeneityDiffuse2013; @sarkozyMutationalLandscapeGray2021a]| |
|
| 101 | -|[LUZP4](LUZP4)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 102 | -|[MRGPRF](MRGPRF)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 103 | -|[NIN](NIN)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 104 | -|[OGDHL](OGDHL)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 105 | -|[PCDHB2](PCDHB2)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 106 | -|[PCSK2](PCSK2)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 107 | -|[PDLIM3](PDLIM3)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 108 | -|[PLXNB3](PLXNB3)|2|[@zhangGenomicLandscapeMantle2014]|[@spinaGeneticsNodalMarginal2016b]| |
|
| 109 | -|[RGS4](RGS4)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 110 | -|[ROBO2](ROBO2)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 111 | -|[SALL3](SALL3)|2|[@zhangGenomicLandscapeMantle2014]|[@loveGeneticLandscapeMutations2012]| |
|
| 112 | -|[SI](SI)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 113 | -|[SLC17A6](SLC17A6)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 114 | -|[SMARCB1](SMARCB1)|2|[@nadeuGenomicEpigenomicInsights2020b]|| |
|
| 115 | -|[SMC1A](SMC1A)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 116 | -|[TBC1D26](TBC1D26)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 117 | -|[TNRC6B](TNRC6B)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 118 | -|[TRPM6](TRPM6)|2|[@beaLandscapeSomaticMutations2013]|| |
|
| 119 | -|[ZNF117](ZNF117)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 120 | -|[ZNF296](ZNF296)|2|[@zhangGenomicLandscapeMantle2014]|| |
|
| 52 | +|[ATP11C](ATP11C)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 53 | +|[B2M](B2M)|2|[Study Overview](papers/pararajalingamCodingNoncodingDrivers2020)[@pararajalingamCodingNoncodingDrivers2020]|[@reichelFlowSortingExome2015a; @morinFrequentMutationHistonemodifying2011]| |
|
| 54 | +|[BCOR](BCOR)|2|[Study Overview](papers/nadeuGenomicEpigenomicInsights2020b)[@nadeuGenomicEpigenomicInsights2020b]|[@jalladesExomeSequencingIdentifies2017]| |
|
| 55 | +|[CDH8](CDH8)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 56 | +|[CHMP4C](CHMP4C)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 57 | +|[COL11A1](COL11A1)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 58 | +|[COL16A1](COL16A1)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 59 | +|[CRYBG3](CRYBG3)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 60 | +|[CTNNA2](CTNNA2)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 61 | +|[DCP1B](DCP1B)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 62 | +|[DHDH](DHDH)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 63 | +|[DLC1](DLC1)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 64 | +|[DLGAP2](DLGAP2)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 65 | +|[DNAJC6](DNAJC6)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 66 | +|[EIF2AK4](EIF2AK4)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 67 | +|[ESX1](ESX1)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 68 | +|[FAT4](FAT4)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|[@morinMutationalStructuralAnalysis2013; @parryWholeExomeSequencing2013]| |
|
| 69 | +|[GRIN2A](GRIN2A)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 70 | +|[HEPH](HEPH)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 71 | +|[KCNC2](KCNC2)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 72 | +|[KIAA1671](KIAA1671)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 73 | +|[KMT2C](KMT2C)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|[@zhouSporadicEndemicBurkitt2019; @zhangGeneticHeterogeneityDiffuse2013; @sarkozyMutationalLandscapeGray2021a]| |
|
| 74 | +|[LUZP4](LUZP4)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 75 | +|[MRGPRF](MRGPRF)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 76 | +|[NIN](NIN)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 77 | +|[OGDHL](OGDHL)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 78 | +|[PCDHB2](PCDHB2)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 79 | +|[PCSK2](PCSK2)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 80 | +|[PDLIM3](PDLIM3)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 81 | +|[PLXNB3](PLXNB3)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|[@spinaGeneticsNodalMarginal2016b]| |
|
| 82 | +|[RGS4](RGS4)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 83 | +|[ROBO2](ROBO2)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 84 | +|[SALL3](SALL3)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|[@loveGeneticLandscapeMutations2012]| |
|
| 85 | +|[SI](SI)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 86 | +|[SLC17A6](SLC17A6)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 87 | +|[SMARCB1](SMARCB1)|2|[Study Overview](papers/nadeuGenomicEpigenomicInsights2020b)[@nadeuGenomicEpigenomicInsights2020b]|| |
|
| 88 | +|[SMC1A](SMC1A)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 89 | +|[TBC1D26](TBC1D26)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 90 | +|[TNRC6B](TNRC6B)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 91 | +|[TRPM6](TRPM6)|2|[Study Overview](papers/beaLandscapeSomaticMutations2013)[@beaLandscapeSomaticMutations2013]|| |
|
| 92 | +|[ZNF117](ZNF117)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 93 | +|[ZNF296](ZNF296)|2|[Study Overview](papers/zhangGenomicLandscapeMantle2014)[@zhangGenomicLandscapeMantle2014]|| |
|
| 121 | 94 | |
| 122 | 95 | |
| 123 | 96 | # References |
PMBL_genes.md
| ... | ... | @@ -7,57 +7,7 @@ link-citations: true |
| 7 | 7 | |
| 8 | 8 | ## Origins of PMBL genes |
| 9 | 9 | |
| 10 | -```mermaid |
|
| 11 | ---- |
|
| 12 | -config: |
|
| 13 | - sankey: |
|
| 14 | - showValues: false |
|
| 15 | - linkColor: target |
|
| 16 | - width: 800 |
|
| 17 | - height: 550 |
|
| 18 | - nodeAlignment: right |
|
| 19 | ---- |
|
| 20 | -sankey-beta |
|
| 21 | -Tiacci 2018, Tier 1 PMBL genes, 1 |
|
| 22 | -Tiacci 2018, Tier 2 PMBL genes, 9 |
|
| 23 | -Duns 2021, Tier 1 PMBL genes, 5 |
|
| 24 | -Duns 2021, Tier 2 PMBL genes, 8 |
|
| 25 | -Desch 2020, Tier 1 PMBL genes, 1 |
|
| 26 | -Desch 2020, Tier 2 PMBL genes, 9 |
|
| 27 | -Weniger 2006, Tier 1 PMBL genes, 1 |
|
| 28 | -Weniger 2006, Tier 2 PMBL genes, 1 |
|
| 29 | -Gomez 2023, Tier 1 PMBL genes, 2 |
|
| 30 | -Gomez 2023, Tier 2 PMBL genes, 5 |
|
| 31 | -Wienand 2019, Tier 1 PMBL genes, 4 |
|
| 32 | -Wienand 2019, Tier 2 PMBL genes, 3 |
|
| 33 | -Otto 2012, Tier 1 PMBL genes, 2 |
|
| 34 | -Reichel 2015, Tier 1 PMBL genes, 11 |
|
| 35 | -Reichel 2015, Tier 2 PMBL genes, 18 |
|
| 36 | -Sarkozy 2021, Tier 1 PMBL genes, 5 |
|
| 37 | -Sarkozy 2021, Tier 2 PMBL genes, 6 |
|
| 38 | -Mottok 2019, Tier 1 PMBL genes, 6 |
|
| 39 | -Mottok 2019, Tier 2 PMBL genes, 15 |
|
| 40 | -PMBL genes, PMBL-exome, 13 |
|
| 41 | -PMBL-exome, Duns 2021, 13 |
|
| 42 | -PMBL genes, PMBL-exome, 10 |
|
| 43 | -PMBL-exome, Tiacci 2018, 10 |
|
| 44 | -PMBL genes, PMBL-panel, 10 |
|
| 45 | -PMBL-panel, Desch 2020, 10 |
|
| 46 | -PMBL genes, PMBL-exome, 7 |
|
| 47 | -PMBL-exome, Gomez 2023, 7 |
|
| 48 | -PMBL genes, PMBL-Sanger, 2 |
|
| 49 | -PMBL-Sanger, Weniger 2006, 2 |
|
| 50 | -PMBL genes, PMBL-exome, 7 |
|
| 51 | -PMBL-exome, Wienand 2019, 7 |
|
| 52 | -PMBL genes, PMBL-exome, 29 |
|
| 53 | -PMBL-exome, Reichel 2015, 29 |
|
| 54 | -PMBL genes, PMBL-Array/Sanger, 2 |
|
| 55 | -PMBL-Array/Sanger, Otto 2012, 2 |
|
| 56 | -PMBL genes, PMBL-exome, 11 |
|
| 57 | -PMBL-exome, Sarkozy 2021, 11 |
|
| 58 | -PMBL genes, PMBL-exome, 21 |
|
| 59 | -PMBL-exome, Mottok 2019, 21 |
|
| 60 | -``` |
|
| 10 | + |
|
| 61 | 11 | |
| 62 | 12 | ## Tier 1 PMBL genes |
| 63 | 13 | |
| ... | ... | @@ -65,82 +15,82 @@ PMBL-exome, Mottok 2019, 21 |
| 65 | 15 | |
| 66 | 16 | |Gene|Tier| First PMBL evidence | Other entities | |
| 67 | 17 | |:-:|:-:|:-|:-| |
| 68 | -|[ACTB](ACTB)|1|[@wienandGenomicAnalysesFlowsorted2019b]|[@lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 69 | -|[ARID1A](ARID1A)|1|[@wienandGenomicAnalysesFlowsorted2019b]|[@rossiCodingGenomeSplenic2012c; @zhangGeneticHeterogeneityDiffuse2013; @loveGeneticLandscapeMutations2012; @krysiakRecurrentSomaticMutations2017b]| |
|
| 70 | -|[ARID5B](ARID5B)|1|[@gomezUltraDeepSequencingReveals2023]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 71 | -|[B2M](B2M)|1|[@reichelFlowSortingExome2015a]|[@pararajalingamCodingNoncodingDrivers2020; @morinFrequentMutationHistonemodifying2011]| |
|
| 72 | -|[BIRC6](BIRC6)|1|[@sarkozyMutationalLandscapeGray2021a]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 73 | -|[BTG1](BTG1)|1|[@sarkozyMutationalLandscapeGray2021a]|[@burkhardtClinicalRelevanceMolecular2022b; @morinFrequentMutationHistonemodifying2011]| |
|
| 74 | -|[CD58](CD58)|1|[@schneiderAlterationsCD58Gene2015a]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 75 | -|[CD83](CD83)|1|[@dunsCharacterizationDLBCLPMBL2021b]|[@morinMutationalStructuralAnalysis2013; @russler-germainMutationsAssociatedProgression2023b; @paneaWholeGenomeLandscape2019]| |
|
| 76 | -|[CDKN2A](CDKN2A)|1||[@spinaGeneticsNodalMarginal2016b; @morinMutationalStructuralAnalysis2013; @grandeGenomewideDiscoverySomatic2019]| |
|
| 77 | -|[CHD8](CHD8)|1||[@grandeGenomewideDiscoverySomatic2019; @reddyGeneticFunctionalDrivers2017]| |
|
| 78 | -|[CIITA](CIITA)|1|[@mottokGenomicAlterationsCIITA2015b]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 79 | -|[CISH](CISH)|1|[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 80 | -|[CREBBP](CREBBP)|1|[@dunsCharacterizationDLBCLPMBL2021b]|[@pasqualucciInactivatingMutationsAcetyltransferase2011a; @loveGeneticLandscapeMutations2012; @parryWholeExomeSequencing2013]| |
|
| 81 | -|[CSF2RB](CSF2RB)|1|[@reichelFlowSortingExome2015a]|| |
|
| 82 | -|[DDX3X](DDX3X)|1|[@mottokIntegrativeGenomicAnalysis2019b]|[@schmitzBurkittLymphomaPathogenesis2012; @schmitzGeneticsPathogenesisDiffuse2018a]| |
|
| 83 | -|[DTX1](DTX1)|1|[@gomezUltraDeepSequencingReveals2023]|[@schmitzGeneticsPathogenesisDiffuse2018a; @paneaWholeGenomeLandscape2019; @rossiCodingGenomeSplenic2012c]| |
|
| 84 | -|[DUSP2](DUSP2)|1|[@dunsCharacterizationDLBCLPMBL2021b]|[@morinMutationalStructuralAnalysis2013]| |
|
| 85 | -|[EBF1](EBF1)|1|[@reichelFlowSortingExome2015a]|[@thomasGeneticSubgroupsInform2023; @bohleRoleEarlyBcell2013]| |
|
| 86 | -|[EEF1A1](EEF1A1)|1|[@reichelFlowSortingExome2015a]|[@hubschmannMutationalMechanismsShaping2021b]| |
|
| 18 | +|[ACTB](ACTB)|1|[Study Overview](papers/wienandGenomicAnalysesFlowsorted2019b)[@wienandGenomicAnalysesFlowsorted2019b]|[@lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 19 | +|[ARID1A](ARID1A)|1|[Study Overview](papers/wienandGenomicAnalysesFlowsorted2019b)[@wienandGenomicAnalysesFlowsorted2019b]|[@zhangGeneticHeterogeneityDiffuse2013; @krysiakRecurrentSomaticMutations2017b; @loveGeneticLandscapeMutations2012; @rossiCodingGenomeSplenic2012c]| |
|
| 20 | +|[ARID5B](ARID5B)|1|[Study Overview](papers/gomezUltraDeepSequencingReveals2023)[@gomezUltraDeepSequencingReveals2023]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 21 | +|[B2M](B2M)|1|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@pararajalingamCodingNoncodingDrivers2020; @morinFrequentMutationHistonemodifying2011]| |
|
| 22 | +|[BIRC6](BIRC6)|1|[Study Overview](papers/sarkozyMutationalLandscapeGray2021a)[@sarkozyMutationalLandscapeGray2021a]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 23 | +|[BTG1](BTG1)|1|[Study Overview](papers/sarkozyMutationalLandscapeGray2021a)[@sarkozyMutationalLandscapeGray2021a]|[@morinFrequentMutationHistonemodifying2011; @burkhardtClinicalRelevanceMolecular2022b]| |
|
| 24 | +|[CD58](CD58)|1|[Study Overview](papers/schneiderAlterationsCD58Gene2015a)[@schneiderAlterationsCD58Gene2015a]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 25 | +|[CD83](CD83)|1|[Study Overview](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|[@russler-germainMutationsAssociatedProgression2023b; @paneaWholeGenomeLandscape2019; @morinMutationalStructuralAnalysis2013]| |
|
| 26 | +|[CDKN2A](CDKN2A)|1||[@grandeGenomewideDiscoverySomatic2019; @morinMutationalStructuralAnalysis2013; @spinaGeneticsNodalMarginal2016b]| |
|
| 27 | +|[CHD8](CHD8)|1||[@reddyGeneticFunctionalDrivers2017; @grandeGenomewideDiscoverySomatic2019]| |
|
| 28 | +|[CIITA](CIITA)|1|[Study Overview](papers/mottokGenomicAlterationsCIITA2015b)[@mottokGenomicAlterationsCIITA2015b]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 29 | +|[CISH](CISH)|1|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 30 | +|[CREBBP](CREBBP)|1|[Study Overview](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|[@loveGeneticLandscapeMutations2012; @pasqualucciInactivatingMutationsAcetyltransferase2011a; @parryWholeExomeSequencing2013]| |
|
| 31 | +|[CSF2RB](CSF2RB)|1|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|| |
|
| 32 | +|[DDX3X](DDX3X)|1|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|[@schmitzGeneticsPathogenesisDiffuse2018a; @schmitzBurkittLymphomaPathogenesis2012]| |
|
| 33 | +|[DTX1](DTX1)|1|[Study Overview](papers/gomezUltraDeepSequencingReveals2023)[@gomezUltraDeepSequencingReveals2023]|[@rossiCodingGenomeSplenic2012c; @schmitzGeneticsPathogenesisDiffuse2018a; @loveGeneticLandscapeMutations2012]| |
|
| 34 | +|[DUSP2](DUSP2)|1|[Study Overview](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|[@lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 35 | +|[EBF1](EBF1)|1|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@thomasGeneticSubgroupsInform2023; @bohleRoleEarlyBcell2013]| |
|
| 36 | +|[EEF1A1](EEF1A1)|1|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@hubschmannMutationalMechanismsShaping2021b]| |
|
| 87 | 37 | |[ETS1](ETS1)|1||[@paneaWholeGenomeLandscape2019; @morinFrequentMutationHistonemodifying2011]| |
| 88 | 38 | |[EWSR1](EWSR1)|1||[@pararajalingamCodingNoncodingDrivers2020]| |
| 89 | -|[EZH2](EZH2)|1|[@mottokIntegrativeGenomicAnalysis2019b]|[@morinSomaticMutationsAltering2010a; @loveGeneticLandscapeMutations2012]| |
|
| 39 | +|[EZH2](EZH2)|1|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|[@morinSomaticMutationsAltering2010a; @loveGeneticLandscapeMutations2012]| |
|
| 90 | 40 | |[FAS](FAS)|1||[@spinaGeneticsNodalMarginal2016b; @schollMutationsRegionFAS2007]| |
| 91 | 41 | |[FAT1](FAT1)|1||[@spinaGeneticsNodalMarginal2016b]| |
| 92 | -|[FAT4](FAT4)|1||[@zhangGenomicLandscapeMantle2014; @morinMutationalStructuralAnalysis2013; @parryWholeExomeSequencing2013]| |
|
| 93 | -|[GNA13](GNA13)|1|[@reichelFlowSortingExome2015a]|[@morinFrequentMutationHistonemodifying2011; @loveGeneticLandscapeMutations2012]| |
|
| 94 | -|[HIST1H1B](HIST1H1B)|1|[@sarkozyMutationalLandscapeGray2021a]|[@chapuyMolecularSubtypesDiffuse2018b; @krysiakRecurrentSomaticMutations2017b]| |
|
| 95 | -|[HIST1H1C](HIST1H1C)|1||[@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]| |
|
| 96 | -|[HIST1H1D](HIST1H1D)|1||[@krysiakRecurrentSomaticMutations2017b; @morinMutationalStructuralAnalysis2013; @jalladesExomeSequencingIdentifies2017]| |
|
| 97 | -|[HIST1H1E](HIST1H1E)|1|[@reichelFlowSortingExome2015a]|[@grandeGenomewideDiscoverySomatic2019; @morinMutationalStructuralAnalysis2013; @krysiakRecurrentSomaticMutations2017b]| |
|
| 98 | -|[HLA-B](HLA-B)|1|[@wienandGenomicAnalysesFlowsorted2019b]|| |
|
| 99 | -|[IL4R](IL4R)|1|[@viganoSomaticIL4RMutations2018b]|[@dunsCharacterizationDLBCLPMBL2021b]| |
|
| 100 | -|[IRF8](IRF8)|1|[@mottokIntegrativeGenomicAnalysis2019b]|[@paneaWholeGenomeLandscape2019; @morinFrequentMutationHistonemodifying2011]| |
|
| 101 | -|[ITPKB](ITPKB)|1|[@reichelFlowSortingExome2015a]|[@schmitzGeneticsPathogenesisDiffuse2018a]| |
|
| 102 | -|[JAK1](JAK1)|1|[@mottokIntegrativeGenomicAnalysis2019b]|[@zhangGeneticHeterogeneityDiffuse2013]| |
|
| 103 | -|[KMT2C](KMT2C)|1|[@sarkozyMutationalLandscapeGray2021a]|[@zhouSporadicEndemicBurkitt2019; @zhangGeneticHeterogeneityDiffuse2013; @zhangGenomicLandscapeMantle2014]| |
|
| 104 | -|[LTB](LTB)|1|[@deschGenotypingCirculatingTumor2020]|[@chapuyMolecularSubtypesDiffuse2018b; @paneaWholeGenomeLandscape2019]| |
|
| 105 | -|[MAP3K14](MAP3K14)|1|[@ottoGeneticLesionsTRAF32012a]|[@rossiAlterationBIRC3Multiple2011a]| |
|
| 106 | -|[MS4A1](MS4A1)|1|[@mottokIntegrativeGenomicAnalysis2019b]|[@rushtonGeneticEvolutionaryPatterns2020]| |
|
| 107 | -|[NFKBIA](NFKBIA)|1|[@wienandGenomicAnalysesFlowsorted2019b]|[@lakeMutationsNFKBIAEncoding2009; @russler-germainMutationsAssociatedProgression2023b]| |
|
| 108 | -|[NFKBIE](NFKBIE)|1|[@mansouriFrequentNFKBIEDeletions2016]|[@morinGeneticLandscapesRelapsed2016; @pararajalingamCodingNoncodingDrivers2020]| |
|
| 42 | +|[FAT4](FAT4)|1||[@morinMutationalStructuralAnalysis2013; @parryWholeExomeSequencing2013; @zhangGenomicLandscapeMantle2014]| |
|
| 43 | +|[GNA13](GNA13)|1|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@morinFrequentMutationHistonemodifying2011; @loveGeneticLandscapeMutations2012]| |
|
| 44 | +|[HIST1H1B](HIST1H1B)|1|[Study Overview](papers/sarkozyMutationalLandscapeGray2021a)[@sarkozyMutationalLandscapeGray2021a]|[@chapuyMolecularSubtypesDiffuse2018b; @krysiakRecurrentSomaticMutations2017b]| |
|
| 45 | +|[HIST1H1C](HIST1H1C)|1||[@paneaWholeGenomeLandscape2019; @morinFrequentMutationHistonemodifying2011]| |
|
| 46 | +|[HIST1H1D](HIST1H1D)|1||[@morinMutationalStructuralAnalysis2013; @krysiakRecurrentSomaticMutations2017b; @jalladesExomeSequencingIdentifies2017]| |
|
| 47 | +|[HIST1H1E](HIST1H1E)|1|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@lohrDiscoveryPrioritizationSomatic2012a; @grandeGenomewideDiscoverySomatic2019; @krysiakRecurrentSomaticMutations2017b]| |
|
| 48 | +|[HLA-B](HLA-B)|1|[Study Overview](papers/wienandGenomicAnalysesFlowsorted2019b)[@wienandGenomicAnalysesFlowsorted2019b]|[@lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 49 | +|[IL4R](IL4R)|1|[Study Overview](papers/viganoSomaticIL4RMutations2018b)[@viganoSomaticIL4RMutations2018b]|[@dunsCharacterizationDLBCLPMBL2021b]| |
|
| 50 | +|[IRF8](IRF8)|1|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|[@paneaWholeGenomeLandscape2019; @morinFrequentMutationHistonemodifying2011]| |
|
| 51 | +|[ITPKB](ITPKB)|1|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@schmitzGeneticsPathogenesisDiffuse2018a]| |
|
| 52 | +|[JAK1](JAK1)|1|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|[@zhangGeneticHeterogeneityDiffuse2013]| |
|
| 53 | +|[KMT2C](KMT2C)|1|[Study Overview](papers/sarkozyMutationalLandscapeGray2021a)[@sarkozyMutationalLandscapeGray2021a]|[@zhangGeneticHeterogeneityDiffuse2013; @zhangGenomicLandscapeMantle2014; @zhouSporadicEndemicBurkitt2019]| |
|
| 54 | +|[LTB](LTB)|1|[Study Overview](papers/deschGenotypingCirculatingTumor2020)[@deschGenotypingCirculatingTumor2020]|[@chapuyMolecularSubtypesDiffuse2018b; @paneaWholeGenomeLandscape2019]| |
|
| 55 | +|[MAP3K14](MAP3K14)|1|[Study Overview](papers/ottoGeneticLesionsTRAF32012a)[@ottoGeneticLesionsTRAF32012a]|[@rossiAlterationBIRC3Multiple2011a]| |
|
| 56 | +|[MS4A1](MS4A1)|1|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|[@rushtonGeneticEvolutionaryPatterns2020]| |
|
| 57 | +|[NFKBIA](NFKBIA)|1|[Study Overview](papers/wienandGenomicAnalysesFlowsorted2019b)[@wienandGenomicAnalysesFlowsorted2019b]|[@russler-germainMutationsAssociatedProgression2023b; @lakeMutationsNFKBIAEncoding2009]| |
|
| 58 | +|[NFKBIE](NFKBIE)|1|[Study Overview](papers/mansouriFrequentNFKBIEDeletions2016)[@mansouriFrequentNFKBIEDeletions2016]|[@pararajalingamCodingNoncodingDrivers2020; @morinGeneticLandscapesRelapsed2016]| |
|
| 109 | 59 | |[OSBPL10](OSBPL10)|1||[@arthurGenomewideDiscoverySomatic2018]| |
| 110 | -|[P2RY8](P2RY8)|1||[@muppidiLossSignalingGa132014b; @lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 60 | +|[P2RY8](P2RY8)|1||[@lohrDiscoveryPrioritizationSomatic2012a; @muppidiLossSignalingGa132014b]| |
|
| 111 | 61 | |[PCLO](PCLO)|1||[@lohrDiscoveryPrioritizationSomatic2012a]| |
| 112 | 62 | |[PHIP](PHIP)|1||| |
| 113 | -|[PIM1](PIM1)|1|[@dunsCharacterizationDLBCLPMBL2021b]|[@pasqualucciHypermutationMultipleProtooncogenes2001a; @burkhardtClinicalRelevanceMolecular2022b]| |
|
| 114 | -|[PIM2](PIM2)|1|[@reichelFlowSortingExome2015a]|[@arthurGenomewideDiscoverySomatic2018]| |
|
| 115 | -|[PRKDC](PRKDC)|1||[@schmitzGeneticsPathogenesisDiffuse2018a; @hubschmannMutationalMechanismsShaping2021b]| |
|
| 116 | -|[PTPN1](PTPN1)|1|[@gunawardanaRecurrentSomaticMutations2014c]|| |
|
| 63 | +|[PIM1](PIM1)|1|[Study Overview](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|[@pasqualucciHypermutationMultipleProtooncogenes2001a; @burkhardtClinicalRelevanceMolecular2022b]| |
|
| 64 | +|[PIM2](PIM2)|1|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@arthurGenomewideDiscoverySomatic2018]| |
|
| 65 | +|[PRKDC](PRKDC)|1||[@hubschmannMutationalMechanismsShaping2021b; @schmitzGeneticsPathogenesisDiffuse2018a]| |
|
| 66 | +|[PTPN1](PTPN1)|1|[Study Overview](papers/gunawardanaRecurrentSomaticMutations2014c)[@gunawardanaRecurrentSomaticMutations2014c]|| |
|
| 117 | 67 | |[PTPRD](PTPRD)|1||[@spinaGeneticsNodalMarginal2016b]| |
| 118 | 68 | |[RHOA](RHOA)|1||[@richterRecurrentMutationID32012a]| |
| 119 | 69 | |[S1PR2](S1PR2)|1||[@muppidiLossSignalingGa132014b; @morinFrequentMutationHistonemodifying2011]| |
| 120 | -|[SGK1](SGK1)|1|[@dunsCharacterizationDLBCLPMBL2021b]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 121 | -|[SIN3A](SIN3A)|1||[@grandeGenomewideDiscoverySomatic2019; @rossiCodingGenomeSplenic2012c]| |
|
| 70 | +|[SGK1](SGK1)|1|[Study Overview](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 71 | +|[SIN3A](SIN3A)|1||[@rossiCodingGenomeSplenic2012c; @grandeGenomewideDiscoverySomatic2019]| |
|
| 122 | 72 | |[SMARCA2](SMARCA2)|1||| |
| 123 | -|[SMARCA4](SMARCA4)|1||[@nadeuGenomicEpigenomicInsights2020b; @krysiakRecurrentSomaticMutations2017b; @richterRecurrentMutationID32012a; @zhangGeneticHeterogeneityDiffuse2013]| |
|
| 124 | -|[SOCS1](SOCS1)|1|[@wenigerMutationsTumorSuppressor2006a]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 125 | -|[SPEN](SPEN)|1|[@sarkozyMutationalLandscapeGray2021a]|[@rossiCodingGenomeSplenic2012c]| |
|
| 126 | -|[STAT3](STAT3)|1||[@ohgamiSTAT3MutationsAre2014]| |
|
| 127 | -|[STAT6](STAT6)|1|[@ritzRecurrentMutationsSTAT62009a]|[@yildizActivatingSTAT6Mutations2015c]| |
|
| 73 | +|[SMARCA4](SMARCA4)|1||[@nadeuGenomicEpigenomicInsights2020b; @krysiakRecurrentSomaticMutations2017b; @richterRecurrentMutationID32012a; @lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 74 | +|[SOCS1](SOCS1)|1|[Study Overview](papers/wenigerMutationsTumorSuppressor2006a)[@wenigerMutationsTumorSuppressor2006a]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 75 | +|[SPEN](SPEN)|1|[Study Overview](papers/sarkozyMutationalLandscapeGray2021a)[@sarkozyMutationalLandscapeGray2021a]|[@rossiCodingGenomeSplenic2012c]| |
|
| 76 | +|[STAT3](STAT3)|1||[@lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 77 | +|[STAT6](STAT6)|1|[Study Overview](papers/ritzRecurrentMutationsSTAT62009a)[@ritzRecurrentMutationsSTAT62009a]|[@yildizActivatingSTAT6Mutations2015c]| |
|
| 128 | 78 | |[TAP1](TAP1)|1||[@schmitzGeneticsPathogenesisDiffuse2018a]| |
| 129 | -|[TBL1XR1](TBL1XR1)|1||[@mareschalWholeExomeSequencing2016; @rossiCodingGenomeSplenic2012c]| |
|
| 79 | +|[TBL1XR1](TBL1XR1)|1||[@rossiCodingGenomeSplenic2012c; @lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 130 | 80 | |[TCF3](TCF3)|1||[@schmitzBurkittLymphomaPathogenesis2012]| |
| 131 | 81 | |[TET3](TET3)|1||| |
| 132 | 82 | |[TMSB4X](TMSB4X)|1||[@albuquerqueEnhancingKnowledgeDiscovery2017a]| |
| 133 | -|[TNFAIP3](TNFAIP3)|1|[@schmitzTNFAIP3A20Tumor2009a]|[@rossiAlterationBIRC3Multiple2011a; @compagnoMutationsMultipleGenes2009a]| |
|
| 83 | +|[TNFAIP3](TNFAIP3)|1|[Study Overview](papers/schmitzTNFAIP3A20Tumor2009a)[@schmitzTNFAIP3A20Tumor2009a]|[@compagnoMutationsMultipleGenes2009a; @rossiAlterationBIRC3Multiple2011a]| |
|
| 134 | 84 | |[TNFRSF1B](TNFRSF1B)|1||| |
| 135 | -|[TP53](TP53)|1|[@tiacciPervasiveMutationsJAKSTAT2018b]|[@beaLandscapeSomaticMutations2013; @morinFrequentMutationHistonemodifying2011; @wildaInactivationARFMDM2p53Pathway2004; @rossiCodingGenomeSplenic2012c]| |
|
| 136 | -|[TRAF3](TRAF3)|1|[@ottoGeneticLesionsTRAF32012a]|[@rossiAlterationBIRC3Multiple2011a; @pasqualucciAnalysisCodingGenome2011]| |
|
| 137 | -|[UBE2A](UBE2A)|1|[@reichelFlowSortingExome2015a]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 138 | -|[UBR5](UBR5)|1||[@zhangGeneticHeterogeneityDiffuse2013; @pararajalingamCodingNoncodingDrivers2020]| |
|
| 139 | -|[UNC5C](UNC5C)|1||| |
|
| 140 | -|[VPS13B](VPS13B)|1||| |
|
| 141 | -|[WEE1](WEE1)|1|[@reichelFlowSortingExome2015a]|[@schmitzGeneticsPathogenesisDiffuse2018a]| |
|
| 142 | -|[XPO1](XPO1)|1|[@jardinRecurrentMutationsExportin2016a]|[@mareschalWholeExomeSequencing2016]| |
|
| 143 | -|[ZFP36L1](ZFP36L1)|1|[@reichelFlowSortingExome2015a]|[@paneaWholeGenomeLandscape2019; @morinFrequentMutationHistonemodifying2011]| |
|
| 85 | +|[TP53](TP53)|1|[Study Overview](papers/tiacciPervasiveMutationsJAKSTAT2018b)[@tiacciPervasiveMutationsJAKSTAT2018b]|[@rossiCodingGenomeSplenic2012c; @morinFrequentMutationHistonemodifying2011; @wildaInactivationARFMDM2p53Pathway2004; @beaLandscapeSomaticMutations2013; @lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 86 | +|[TRAF3](TRAF3)|1|[Study Overview](papers/ottoGeneticLesionsTRAF32012a)[@ottoGeneticLesionsTRAF32012a]|[@rossiAlterationBIRC3Multiple2011a; @pasqualucciAnalysisCodingGenome2011]| |
|
| 87 | +|[UBE2A](UBE2A)|1|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 88 | +|[UBR5](UBR5)|1||[@pararajalingamCodingNoncodingDrivers2020; @zhangGeneticHeterogeneityDiffuse2013]| |
|
| 89 | +|[UNC5C](UNC5C)|1||[@lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 90 | +|[VPS13B](VPS13B)|1||[@lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 91 | +|[WEE1](WEE1)|1|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@schmitzGeneticsPathogenesisDiffuse2018a]| |
|
| 92 | +|[XPO1](XPO1)|1|[Study Overview](papers/jardinRecurrentMutationsExportin2016a)[@jardinRecurrentMutationsExportin2016a]|[@mareschalWholeExomeSequencing2016]| |
|
| 93 | +|[ZFP36L1](ZFP36L1)|1|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@morinFrequentMutationHistonemodifying2011; @paneaWholeGenomeLandscape2019]| |
|
| 144 | 94 | |
| 145 | 95 | ## Tier 2 PMBL genes |
| 146 | 96 | |
| ... | ... | @@ -148,88 +98,88 @@ PMBL-exome, Mottok 2019, 21 |
| 148 | 98 | |
| 149 | 99 | |Gene|Tier| First PMBL evidence | Other entities | |
| 150 | 100 | |:-:|:-:|:-|:-| |
| 151 | -|[ABCA13](ABCA13)|2|[@sarkozyMutationalLandscapeGray2021a]|[@spinaGeneticsNodalMarginal2016b]| |
|
| 152 | -|[ACTG1](ACTG1)|2|[@deschGenotypingCirculatingTumor2020]|[@hubschmannMutationalMechanismsShaping2021b; @spinaGeneticsNodalMarginal2016b]| |
|
| 153 | -|[AKAP6](AKAP6)|2|[@tiacciPervasiveMutationsJAKSTAT2018b]|| |
|
| 154 | -|[ARIH2](ARIH2)|2|[@reichelFlowSortingExome2015a]|| |
|
| 155 | -|[AXDND1](AXDND1)|2|[@gomezUltraDeepSequencingReveals2023]|| |
|
| 156 | -|[BCL2](BCL2)|2|[@sarkozyMutationalLandscapeGray2021a]|[@burkhardtClinicalRelevanceMolecular2022b; @tanakaFrequentIncidenceSomatic1992; @morinFrequentMutationHistonemodifying2011]| |
|
| 157 | -|[BCL7A](BCL7A)|2|[@reichelFlowSortingExome2015a]|[@krysiakRecurrentSomaticMutations2017b; @grandeGenomewideDiscoverySomatic2019; @arthurGenomewideDiscoverySomatic2018]| |
|
| 158 | -|[BIRC3](BIRC3)|2|[@dunsCharacterizationDLBCLPMBL2021b]|[@beaLandscapeSomaticMutations2013; @rossiAlterationBIRC3Multiple2011a; @arthurGenomewideDiscoverySomatic2018]| |
|
| 159 | -|[CCND3](CCND3)|2|[@deschGenotypingCirculatingTumor2020]|[@morinFrequentMutationHistonemodifying2011; @jalladesExomeSequencingIdentifies2017; @richterRecurrentMutationID32012a]| |
|
| 160 | -|[CDH2](CDH2)|2|[@deschGenotypingCirculatingTumor2020]|| |
|
| 161 | -|[CDH5](CDH5)|2|[@gomezUltraDeepSequencingReveals2023]|| |
|
| 162 | -|[CXCR5](CXCR5)|2|[@mottokIntegrativeGenomicAnalysis2019b]|[@schmitzGeneticsPathogenesisDiffuse2018a]| |
|
| 163 | -|[DGKB](DGKB)|2|[@tiacciPervasiveMutationsJAKSTAT2018b]|| |
|
| 164 | -|[DMD](DMD)|2|[@reichelFlowSortingExome2015a]|| |
|
| 165 | -|[DNAH12](DNAH12)|2|[@wienandGenomicAnalysesFlowsorted2019b]|| |
|
| 166 | -|[EGR1](EGR1)|2|[@reichelFlowSortingExome2015a]|[@rossiCodingGenomeSplenic2012c; @krysiakRecurrentSomaticMutations2017b]| |
|
| 167 | -|[EPHA7](EPHA7)|2|[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 168 | -|[EZR](EZR)|2|[@deschGenotypingCirculatingTumor2020]|| |
|
| 169 | -|[FOXO1](FOXO1)|2|[@dunsCharacterizationDLBCLPMBL2021b]|[@morinFrequentMutationHistonemodifying2011; @schmitzBurkittLymphomaPathogenesis2012]| |
|
| 170 | -|[GCSAM](GCSAM)|2|[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 171 | -|[GPR126](GPR126)|2|[@wenigerMutationsTumorSuppressor2006a]|| |
|
| 172 | -|[HECW2](HECW2)|2|[@reichelFlowSortingExome2015a]|| |
|
| 173 | -|[HELLS](HELLS)|2|[@reichelFlowSortingExome2015a]|| |
|
| 174 | -|[HIST1H2BC](HIST1H2BC)|2|[@mottokIntegrativeGenomicAnalysis2019b]|[@reddyGeneticFunctionalDrivers2017; @krysiakRecurrentSomaticMutations2017b]| |
|
| 175 | -|[HIST1H3B](HIST1H3B)|2|[@reichelFlowSortingExome2015a]|[@zhangGeneticHeterogeneityDiffuse2013]| |
|
| 176 | -|[HIST1H4C](HIST1H4C)|2|[@reichelFlowSortingExome2015a]|| |
|
| 177 | -|[HIST1H4E](HIST1H4E)|2|[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 178 | -|[HIST1H4J](HIST1H4J)|2|[@mottokIntegrativeGenomicAnalysis2019b]|[@paneaWholeGenomeLandscape2019]| |
|
| 179 | -|[HLA-A](HLA-A)|2|[@deschGenotypingCirculatingTumor2020]|| |
|
| 180 | -|[HLA-C](HLA-C)|2|[@gomezUltraDeepSequencingReveals2023]|| |
|
| 181 | -|[HRNR](HRNR)|2|[@dunsCharacterizationDLBCLPMBL2021b]|| |
|
| 182 | -|[IGLL5](IGLL5)|2|[@deschGenotypingCirculatingTumor2020]|[@russler-germainMutationsAssociatedProgression2023b; @paneaWholeGenomeLandscape2019]| |
|
| 183 | -|[IKBKB](IKBKB)|2|[@wienandGenomicAnalysesFlowsorted2019b]|[@reddyGeneticFunctionalDrivers2017; @rossiAlterationBIRC3Multiple2011a]| |
|
| 184 | -|[IL13RA1](IL13RA1)|2|[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 185 | -|[IL1RAPL2](IL1RAPL2)|2|[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 186 | -|[IRF2BP2](IRF2BP2)|2|[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 187 | -|[IRF4](IRF4)|2|[@mottokIntegrativeGenomicAnalysis2019b]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 101 | +|[ABCA13](ABCA13)|2|[Study Overview](papers/sarkozyMutationalLandscapeGray2021a)[@sarkozyMutationalLandscapeGray2021a]|[@spinaGeneticsNodalMarginal2016b]| |
|
| 102 | +|[ACTG1](ACTG1)|2|[Study Overview](papers/deschGenotypingCirculatingTumor2020)[@deschGenotypingCirculatingTumor2020]|[@hubschmannMutationalMechanismsShaping2021b; @spinaGeneticsNodalMarginal2016b]| |
|
| 103 | +|[AKAP6](AKAP6)|2|[Study Overview](papers/tiacciPervasiveMutationsJAKSTAT2018b)[@tiacciPervasiveMutationsJAKSTAT2018b]|| |
|
| 104 | +|[ARIH2](ARIH2)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|| |
|
| 105 | +|[AXDND1](AXDND1)|2|[Study Overview](papers/gomezUltraDeepSequencingReveals2023)[@gomezUltraDeepSequencingReveals2023]|| |
|
| 106 | +|[BCL2](BCL2)|2|[Study Overview](papers/sarkozyMutationalLandscapeGray2021a)[@sarkozyMutationalLandscapeGray2021a]|[@burkhardtClinicalRelevanceMolecular2022b; @tanakaFrequentIncidenceSomatic1992; @morinFrequentMutationHistonemodifying2011]| |
|
| 107 | +|[BCL7A](BCL7A)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@grandeGenomewideDiscoverySomatic2019; @krysiakRecurrentSomaticMutations2017b; @arthurGenomewideDiscoverySomatic2018]| |
|
| 108 | +|[BIRC3](BIRC3)|2|[Study Overview](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|[@beaLandscapeSomaticMutations2013; @arthurGenomewideDiscoverySomatic2018; @rossiAlterationBIRC3Multiple2011a]| |
|
| 109 | +|[CCND3](CCND3)|2|[Study Overview](papers/deschGenotypingCirculatingTumor2020)[@deschGenotypingCirculatingTumor2020]|[@morinFrequentMutationHistonemodifying2011; @richterRecurrentMutationID32012a; @jalladesExomeSequencingIdentifies2017]| |
|
| 110 | +|[CDH2](CDH2)|2|[Study Overview](papers/deschGenotypingCirculatingTumor2020)[@deschGenotypingCirculatingTumor2020]|| |
|
| 111 | +|[CDH5](CDH5)|2|[Study Overview](papers/gomezUltraDeepSequencingReveals2023)[@gomezUltraDeepSequencingReveals2023]|| |
|
| 112 | +|[CXCR5](CXCR5)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|[@schmitzGeneticsPathogenesisDiffuse2018a]| |
|
| 113 | +|[DGKB](DGKB)|2|[Study Overview](papers/tiacciPervasiveMutationsJAKSTAT2018b)[@tiacciPervasiveMutationsJAKSTAT2018b]|| |
|
| 114 | +|[DMD](DMD)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|| |
|
| 115 | +|[DNAH12](DNAH12)|2|[Study Overview](papers/wienandGenomicAnalysesFlowsorted2019b)[@wienandGenomicAnalysesFlowsorted2019b]|| |
|
| 116 | +|[EGR1](EGR1)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@rossiCodingGenomeSplenic2012c; @krysiakRecurrentSomaticMutations2017b]| |
|
| 117 | +|[EPHA7](EPHA7)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 118 | +|[EZR](EZR)|2|[Study Overview](papers/deschGenotypingCirculatingTumor2020)[@deschGenotypingCirculatingTumor2020]|| |
|
| 119 | +|[FOXO1](FOXO1)|2|[Study Overview](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|[@schmitzBurkittLymphomaPathogenesis2012; @morinFrequentMutationHistonemodifying2011]| |
|
| 120 | +|[GCSAM](GCSAM)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 121 | +|[GPR126](GPR126)|2|[Study Overview](papers/wenigerMutationsTumorSuppressor2006a)[@wenigerMutationsTumorSuppressor2006a]|| |
|
| 122 | +|[HECW2](HECW2)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|| |
|
| 123 | +|[HELLS](HELLS)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|| |
|
| 124 | +|[HIST1H2BC](HIST1H2BC)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|[@lohrDiscoveryPrioritizationSomatic2012a; @krysiakRecurrentSomaticMutations2017b]| |
|
| 125 | +|[HIST1H3B](HIST1H3B)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 126 | +|[HIST1H4C](HIST1H4C)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|| |
|
| 127 | +|[HIST1H4E](HIST1H4E)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 128 | +|[HIST1H4J](HIST1H4J)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|[@paneaWholeGenomeLandscape2019]| |
|
| 129 | +|[HLA-A](HLA-A)|2|[Study Overview](papers/deschGenotypingCirculatingTumor2020)[@deschGenotypingCirculatingTumor2020]|[@lohrDiscoveryPrioritizationSomatic2012a]| |
|
| 130 | +|[HLA-C](HLA-C)|2|[Study Overview](papers/gomezUltraDeepSequencingReveals2023)[@gomezUltraDeepSequencingReveals2023]|| |
|
| 131 | +|[HRNR](HRNR)|2|[Study Overview](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|| |
|
| 132 | +|[IGLL5](IGLL5)|2|[Study Overview](papers/deschGenotypingCirculatingTumor2020)[@deschGenotypingCirculatingTumor2020]|[@paneaWholeGenomeLandscape2019; @russler-germainMutationsAssociatedProgression2023b]| |
|
| 133 | +|[IKBKB](IKBKB)|2|[Study Overview](papers/wienandGenomicAnalysesFlowsorted2019b)[@wienandGenomicAnalysesFlowsorted2019b]|[@rossiAlterationBIRC3Multiple2011a; @reddyGeneticFunctionalDrivers2017]| |
|
| 134 | +|[IL13RA1](IL13RA1)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 135 | +|[IL1RAPL2](IL1RAPL2)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 136 | +|[IRF2BP2](IRF2BP2)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 137 | +|[IRF4](IRF4)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|[@morinFrequentMutationHistonemodifying2011]| |
|
| 188 | 138 | |[ITGB2](ITGB2)|2||| |
| 189 | -|[ITPR3](ITPR3)|2|[@tiacciPervasiveMutationsJAKSTAT2018b]|[@loveGeneticLandscapeMutations2012]| |
|
| 190 | -|[JUNB](JUNB)|2|[@mottokIntegrativeGenomicAnalysis2019b]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 191 | -|[KLF2](KLF2)|2|[@deschGenotypingCirculatingTumor2020]|[@jalladesExomeSequencingIdentifies2017; @pasqualucciAnalysisCodingGenome2011]| |
|
| 192 | -|[KMT2D](KMT2D)|2|[@deschGenotypingCirculatingTumor2020]|[@grandeGenomewideDiscoverySomatic2019; @beaLandscapeSomaticMutations2013; @morinFrequentMutationHistonemodifying2011; @rossiCodingGenomeSplenic2012c]| |
|
| 193 | -|[LIMD2](LIMD2)|2|[@gomezUltraDeepSequencingReveals2023]|| |
|
| 194 | -|[LPHN3](LPHN3)|2|[@dunsCharacterizationDLBCLPMBL2021b]|| |
|
| 195 | -|[LRRN3](LRRN3)|2|[@sarkozyMutationalLandscapeGray2021a]|[@morinMutationalStructuralAnalysis2013]| |
|
| 196 | -|[MAGEC2](MAGEC2)|2|[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 197 | -|[MCL1](MCL1)|2|[@dunsCharacterizationDLBCLPMBL2021b]|[@paneaWholeGenomeLandscape2019; @reddyGeneticFunctionalDrivers2017]| |
|
| 198 | -|[MFHAS1](MFHAS1)|2|[@sarkozyMutationalLandscapeGray2021a]|| |
|
| 199 | -|[MPDZ](MPDZ)|2|[@reichelFlowSortingExome2015a]|[@morinMutationalStructuralAnalysis2013]| |
|
| 200 | -|[MYB](MYB)|2|[@deschGenotypingCirculatingTumor2020]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 201 | -|[MYC](MYC)|2|[@dunsCharacterizationDLBCLPMBL2021b]|[@johnstonCmycHypermutationBurkitt1992; @jalladesExomeSequencingIdentifies2017; @pasqualucciHypermutationMultipleProtooncogenes2001a]| |
|
| 202 | -|[NCOR2](NCOR2)|2|[@sarkozyMutationalLandscapeGray2021a]|[@schmitzBurkittLymphomaPathogenesis2012; @spinaGeneticsNodalMarginal2016b]| |
|
| 203 | -|[NEK1](NEK1)|2|[@reichelFlowSortingExome2015a]|| |
|
| 204 | -|[NFKB2](NFKB2)|2|[@mottokIntegrativeGenomicAnalysis2019b]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 139 | +|[ITPR3](ITPR3)|2|[Study Overview](papers/tiacciPervasiveMutationsJAKSTAT2018b)[@tiacciPervasiveMutationsJAKSTAT2018b]|[@loveGeneticLandscapeMutations2012]| |
|
| 140 | +|[JUNB](JUNB)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 141 | +|[KLF2](KLF2)|2|[Study Overview](papers/deschGenotypingCirculatingTumor2020)[@deschGenotypingCirculatingTumor2020]|[@jalladesExomeSequencingIdentifies2017; @pasqualucciAnalysisCodingGenome2011]| |
|
| 142 | +|[KMT2D](KMT2D)|2|[Study Overview](papers/deschGenotypingCirculatingTumor2020)[@deschGenotypingCirculatingTumor2020]|[@rossiCodingGenomeSplenic2012c; @morinFrequentMutationHistonemodifying2011; @grandeGenomewideDiscoverySomatic2019; @beaLandscapeSomaticMutations2013]| |
|
| 143 | +|[LIMD2](LIMD2)|2|[Study Overview](papers/gomezUltraDeepSequencingReveals2023)[@gomezUltraDeepSequencingReveals2023]|| |
|
| 144 | +|[LPHN3](LPHN3)|2|[Study Overview](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|| |
|
| 145 | +|[LRRN3](LRRN3)|2|[Study Overview](papers/sarkozyMutationalLandscapeGray2021a)[@sarkozyMutationalLandscapeGray2021a]|[@morinMutationalStructuralAnalysis2013]| |
|
| 146 | +|[MAGEC2](MAGEC2)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 147 | +|[MCL1](MCL1)|2|[Study Overview](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|[@paneaWholeGenomeLandscape2019; @reddyGeneticFunctionalDrivers2017]| |
|
| 148 | +|[MFHAS1](MFHAS1)|2|[Study Overview](papers/sarkozyMutationalLandscapeGray2021a)[@sarkozyMutationalLandscapeGray2021a]|| |
|
| 149 | +|[MPDZ](MPDZ)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@morinMutationalStructuralAnalysis2013]| |
|
| 150 | +|[MYB](MYB)|2|[Study Overview](papers/deschGenotypingCirculatingTumor2020)[@deschGenotypingCirculatingTumor2020]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 151 | +|[MYC](MYC)|2|[Study Overview](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|[@jalladesExomeSequencingIdentifies2017; @pasqualucciHypermutationMultipleProtooncogenes2001a; @johnstonCmycHypermutationBurkitt1992]| |
|
| 152 | +|[NCOR2](NCOR2)|2|[Study Overview](papers/sarkozyMutationalLandscapeGray2021a)[@sarkozyMutationalLandscapeGray2021a]|[@schmitzBurkittLymphomaPathogenesis2012; @spinaGeneticsNodalMarginal2016b]| |
|
| 153 | +|[NEK1](NEK1)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|| |
|
| 154 | +|[NFKB2](NFKB2)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 205 | 155 | |[NSD2](NSD2)|2||[@beaLandscapeSomaticMutations2013]| |
| 206 | -|[NUP214](NUP214)|2|[@tiacciPervasiveMutationsJAKSTAT2018b]|| |
|
| 207 | -|[OR13C2](OR13C2)|2|[@gomezUltraDeepSequencingReveals2023]|| |
|
| 156 | +|[NUP214](NUP214)|2|[Study Overview](papers/tiacciPervasiveMutationsJAKSTAT2018b)[@tiacciPervasiveMutationsJAKSTAT2018b]|| |
|
| 157 | +|[OR13C2](OR13C2)|2|[Study Overview](papers/gomezUltraDeepSequencingReveals2023)[@gomezUltraDeepSequencingReveals2023]|| |
|
| 208 | 158 | |[PCBP1](PCBP1)|2||[@schmitzBurkittLymphomaPathogenesis2012]| |
| 209 | 159 | |[PCDH7](PCDH7)|2||| |
| 210 | -|[PRUNE2](PRUNE2)|2|[@tiacciPervasiveMutationsJAKSTAT2018b]|| |
|
| 211 | -|[RANBP2](RANBP2)|2|[@reichelFlowSortingExome2015a]|| |
|
| 212 | -|[RBM38](RBM38)|2|[@wienandGenomicAnalysesFlowsorted2019b]|| |
|
| 160 | +|[PRUNE2](PRUNE2)|2|[Study Overview](papers/tiacciPervasiveMutationsJAKSTAT2018b)[@tiacciPervasiveMutationsJAKSTAT2018b]|| |
|
| 161 | +|[RANBP2](RANBP2)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|| |
|
| 162 | +|[RBM38](RBM38)|2|[Study Overview](papers/wienandGenomicAnalysesFlowsorted2019b)[@wienandGenomicAnalysesFlowsorted2019b]|| |
|
| 213 | 163 | |[RDH12](RDH12)|2||| |
| 214 | -|[RELN](RELN)|2|[@sarkozyMutationalLandscapeGray2021a]|| |
|
| 215 | -|[RFTN1](RFTN1)|2|[@dunsCharacterizationDLBCLPMBL2021b]|[@arthurGenomewideDiscoverySomatic2018]| |
|
| 216 | -|[RGS1](RGS1)|2|[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 164 | +|[RELN](RELN)|2|[Study Overview](papers/sarkozyMutationalLandscapeGray2021a)[@sarkozyMutationalLandscapeGray2021a]|| |
|
| 165 | +|[RFTN1](RFTN1)|2|[Study Overview](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|[@arthurGenomewideDiscoverySomatic2018]| |
|
| 166 | +|[RGS1](RGS1)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 217 | 167 | |[SCN9A](SCN9A)|2||| |
| 218 | -|[SENP7](SENP7)|2|[@reichelFlowSortingExome2015a]|| |
|
| 219 | -|[SETD5](SETD5)|2|[@tiacciPervasiveMutationsJAKSTAT2018b]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 220 | -|[SETDB1](SETDB1)|2|[@reichelFlowSortingExome2015a]|| |
|
| 221 | -|[SIAH2](SIAH2)|2|[@reichelFlowSortingExome2015a]|[@hubschmannMutationalMechanismsShaping2021b]| |
|
| 168 | +|[SENP7](SENP7)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|| |
|
| 169 | +|[SETD5](SETD5)|2|[Study Overview](papers/tiacciPervasiveMutationsJAKSTAT2018b)[@tiacciPervasiveMutationsJAKSTAT2018b]|[@reddyGeneticFunctionalDrivers2017]| |
|
| 170 | +|[SETDB1](SETDB1)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|| |
|
| 171 | +|[SIAH2](SIAH2)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@hubschmannMutationalMechanismsShaping2021b]| |
|
| 222 | 172 | |[SMAD3](SMAD3)|2||| |
| 223 | -|[STAT5B](STAT5B)|2|[@tiacciPervasiveMutationsJAKSTAT2018b]|[@zhangGeneticHeterogeneityDiffuse2013]| |
|
| 173 | +|[STAT5B](STAT5B)|2|[Study Overview](papers/tiacciPervasiveMutationsJAKSTAT2018b)[@tiacciPervasiveMutationsJAKSTAT2018b]|[@zhangGeneticHeterogeneityDiffuse2013]| |
|
| 224 | 174 | |[STRAP](STRAP)|2||| |
| 225 | -|[TBC1D15](TBC1D15)|2|[@reichelFlowSortingExome2015a]|| |
|
| 226 | -|[TICRR](TICRR)|2|[@reichelFlowSortingExome2015a]|| |
|
| 227 | -|[TNIP1](TNIP1)|2|[@tiacciPervasiveMutationsJAKSTAT2018b]|| |
|
| 228 | -|[TRIP11](TRIP11)|2|[@reichelFlowSortingExome2015a]|| |
|
| 229 | -|[VMP1](VMP1)|2|[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 230 | -|[WDR87](WDR87)|2|[@dunsCharacterizationDLBCLPMBL2021b]|| |
|
| 231 | -|[ZCCHC11](ZCCHC11)|2|[@tiacciPervasiveMutationsJAKSTAT2018b]|| |
|
| 232 | -|[ZNF217](ZNF217)|2|[@reichelFlowSortingExome2015a]|[@hubschmannMutationalMechanismsShaping2021b]| |
|
| 175 | +|[TBC1D15](TBC1D15)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|| |
|
| 176 | +|[TICRR](TICRR)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|| |
|
| 177 | +|[TNIP1](TNIP1)|2|[Study Overview](papers/tiacciPervasiveMutationsJAKSTAT2018b)[@tiacciPervasiveMutationsJAKSTAT2018b]|| |
|
| 178 | +|[TRIP11](TRIP11)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|| |
|
| 179 | +|[VMP1](VMP1)|2|[Study Overview](papers/mottokIntegrativeGenomicAnalysis2019b)[@mottokIntegrativeGenomicAnalysis2019b]|| |
|
| 180 | +|[WDR87](WDR87)|2|[Study Overview](papers/dunsCharacterizationDLBCLPMBL2021b)[@dunsCharacterizationDLBCLPMBL2021b]|| |
|
| 181 | +|[ZCCHC11](ZCCHC11)|2|[Study Overview](papers/tiacciPervasiveMutationsJAKSTAT2018b)[@tiacciPervasiveMutationsJAKSTAT2018b]|| |
|
| 182 | +|[ZNF217](ZNF217)|2|[Study Overview](papers/reichelFlowSortingExome2015a)[@reichelFlowSortingExome2015a]|[@hubschmannMutationalMechanismsShaping2021b]| |
|
| 233 | 183 | |
| 234 | 184 | |
| 235 | 185 | # References |