ATM.md
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## Overview
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Mutations in this gene were first described in MZL by Braggio et al.[@braggioGenomicAnalysisMarginal2012] then in MCL by Bea et al.[@beaLandscapeSomaticMutations2013] ATM mutations were later described in DLBCL by Reddy et al.[@reddyGeneticFunctionalDrivers2017]
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-[Selective pressure analysis](#mutation-pattern-and-selective-pressure-estimates) did not identify this gene as significantly enriched for either missense or truncating mutations.
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+The role of ATM in DLBCL remains unclear.
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+[Selective pressure analysis](#mutation-pattern-and-selective-pressure-estimates) did not identify this gene as significantly enriched for either missense or truncating mutations, indicating that many of these mutations may represent passengers.
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## Experimental Evidence