BRINP3.md
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[[_TOC_]]
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-<<Warn("In a subsequent reanalysis, the mutation rate in this gene was found to be inflated in the original results")>>
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-Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.<sup>[@reddyGeneticFunctionalDrivers2017]</sup> Subsequent exome and genome-wide studies of DLBCL did not reproduce this observation.
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+## Overview
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+Mutations in this gene were first described in DLBCL in 2017 by Reddy et al.<sup>[@reddyGeneticFunctionalDrivers2017]</sup> Subsequent exome and genome-wide studies of DLBCL did not reproduce this observation.
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## Relevance tier by entity
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|:------:|:----:|-----------------------------------------|
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|![DLBCL](images/icons/DLBCL_tier2.png) |2 |relevance in DLBCL not firmly established[@reddyGeneticFunctionalDrivers2017]|
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+## Warnings
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+<<Warn("In a subsequent reanalysis, the mutation rate in this gene was found to be inflated in the original results")>>
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## Mutation incidence in large patient cohorts (GAMBL reanalysis)
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|Entity|source |frequency (%)|