DDX3X.md
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@@ -14,9 +14,11 @@ These mutations are predominantly loss-of-function (LOF) mutations, affecting th
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%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
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timeline
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title Publication timing
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- 2012-10-04 : Schmitz : BL
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- 2018-04-12 : Schmitz : DLBCL
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- 2019-09-05 : Mottok : PMBL
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+2012-10-04 : Schmitz : BL
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+2017-10-10 : Reddy : DLBCL
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+2018-04-12 : Schmitz : DLBCL
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+2018-10-01 : Arthur : DLBCL
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+2019-09-05 : Mottok : PMBL
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```
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## Relevance tier by entity
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|:------:|:----:|--------------------------------------|
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|![PMBL](images/icons/PMBL_tier1.png)|1|high-confidence PMBL/cHL/GZL gene[@mottokIntegrativeGenomicAnalysis2019b]|
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|![BL](images/icons/BL_tier1.png) |1 | high-confidence BL gene [@schmitzBurkittLymphomaPathogenesis2012]|
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-|![DLBCL](images/icons/DLBCL_tier1.png) |1 | high-confidence DLBCL gene [@schmitzGeneticsPathogenesisDiffuse2018a]|
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+|![DLBCL](images/icons/DLBCL_tier1.png) |1 | high-confidence DLBCL gene [@reddyGeneticFunctionalDrivers2017; @schmitzGeneticsPathogenesisDiffuse2018a; @arthurGenomewideDiscoverySomatic2018]|
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|![FL](images/icons/FL_tier2.png) |2 | Although recurrent, the relevance of mutations in FL is tenuous |
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## Mutation incidence in large patient cohorts (GAMBL reanalysis)