ead27528fa473aeea3bf38b9745407574a7a3322
SMARCA4.md
| ... | ... | @@ -25,24 +25,16 @@ timeline |
| 25 | 25 | |Entity|Tier|Description | |
| 26 | 26 | |:------:|:----:|--------------------------| |
| 27 | 27 | ||1|high-confidence PMBL/cHL/GZL gene| |
| 28 | -| |1-EE[@dengSMARCA4HaploinsufficientCell2024] |high-confidence BL gene [@richterRecurrentMutationID32012]| |
|
| 29 | -| |1-EE[@dengSMARCA4HaploinsufficientCell2024] |high-confidence DLBCL gene[@lohrDiscoveryPrioritizationSomatic2012]| |
|
| 28 | +| |1[@dengSMARCA4HaploinsufficientCell2024] |high-confidence BL gene [@richterRecurrentMutationID32012]| |
|
| 29 | +| |1[@dengSMARCA4HaploinsufficientCell2024] |high-confidence DLBCL gene[@lohrDiscoveryPrioritizationSomatic2012]| |
|
| 30 | 30 | | |1 |high-confidence FL gene [@krysiakRecurrentSomaticMutations2017]| |
| 31 | 31 | | |1 |high-confidence MCL gene [@nadeuGenomicEpigenomicInsights2020]| |
| 32 | 32 | |
| 33 | 33 | ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |
| 34 | 34 | |
| 35 | -|Entity|source |frequency (%)| |
|
| 36 | -|:------:|:---------------------:|:-------------:| |
|
| 37 | -|BL |GAMBL genomes+capture|22.63 | |
|
| 38 | -|BL |Thomas cohort |17.80 | |
|
| 39 | -|BL |Panea cohort |18.80 | |
|
| 40 | -|DLBCL |GAMBL genomes | 3.25 | |
|
| 41 | -|DLBCL |Schmitz cohort | 2.98 | |
|
| 42 | -|DLBCL |Reddy cohort | 3.30 | |
|
| 43 | -|DLBCL |Chapuy cohort | 2.14 | |
|
| 44 | -|FL |GAMBL genomes | 4.16 | |
|
| 45 | -|MCL |GAMBL genomes | 4.74 | |
|
| 35 | +[[include:DLBCL_SMARCA4.md]] |
|
| 36 | +[[include:FL_SMARCA4.md]] |
|
| 37 | +[[include:BL_SMARCA4.md]] |
|
| 46 | 38 | |
| 47 | 39 | ## Mutation pattern and selective pressure estimates |
| 48 | 40 |