EPHB2.md
... ...
@@ -48,5 +48,16 @@ View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/E
48 48
<!-- ORIGIN: loveGeneticLandscapeMutations2012 -->
49 49
<!-- BL: loveGeneticLandscapeMutations2012 -->
50 50
51
+## Representative Mutations
52
+
53
+![](primary/Love_EPHB2.svg)
54
+**Rating**
55
+&starf; &starf; &starf; &star; &star;
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+
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+![](primary/Love_EPHB2_2.svg)
58
+**Rating**
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+&starf; &star; &star; &star; &star;
60
+
61
+
51 62
## References
52 63
1. Love C, Sun Z, Jima D, Li G, Zhang J, Miles R, Richards KL, Dunphy CH, Choi WWL, Srivastava G, Lugar PL, Rizzieri DA, Lagoo AS, Bernal-Mizrachi L, Mann KP, Flowers CR, Naresh KN, Evens AM, Chadburn A, Gordon LI, Czader MB, Gill JI, Hsi ED, Greenough A, Moffitt AB, McKinney M, Banerjee A, Grubor V, Levy S, Dunson DB, Dave SS. The genetic landscape of mutations in Burkitt lymphoma. Nat Genet. 2012 Dec;44(12):1321–1325. PMCID: PMC3674561
papers/loveGeneticLandscapeMutations2012.md
... ...
@@ -64,7 +64,7 @@ All other BL studies, BL Tier 2, 101
64 64
|[EIF2C4](../EIF2C4)|2 |&starf; &star; &star; &star; &star;|
65 65
|[EML2](../EML2)|2 |&starf; &star; &star; &star; &star;|
66 66
|[ENTPD3](../ENTPD3)|2 |&starf; &starf; &star; &star; &star;|
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-|[EPHB2](../EPHB2)|2 ||
67
+|[EPHB2](../EPHB2)|2 |&starf; &starf; &star; &star; &star;|
68 68
|[EZH2](../EZH2)|2 |&starf; &starf; &starf; &starf; &starf;|
69 69
|[FAM129B](../FAM129B)|2 ||
70 70
|[FGFR3](../FGFR3)|2 ||
papers/loveGeneticLandscapeMutations2012.pdf
papers/loveGeneticLandscapeMutations2012_tmp.html
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-<h1 id="lovegeneticlandscapemutations2012">@loveGeneticLandscapeMutations2012</h1>
369
-<h2 id="summary-of-novel-genes">Summary of novel genes</h2>
370
-<table>
371
-<thead>
372
-<tr>
373
-<th style="text-align:center">Entity</th>
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-<th style="text-align:center">Tier 1 genes</th>
375
-<th style="text-align:center">Tier 2 genes</th>
376
-</tr>
377
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-<tbody>
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-<tr>
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-<td style="text-align:center">BL</td>
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-<td style="text-align:center">3</td>
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----
397
-sankey-beta
398
-This study, New Tier 1, 3
399
-New Tier 1, BL Tier 1, 3
400
-This study, New Tier 2, 56
401
-New Tier 2, BL Tier 2, 56
402
-All other BL studies, BL Tier 1, 26
403
-All other BL studies, BL Tier 2, 101
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-</div></code></pre>
405
-<h2 id="novel-genes-reported-in-this-study">Novel genes reported in this study</h2>
406
-<h3 id="tier-1">Tier 1</h3>
407
-<table>
408
-<thead>
409
-<tr>
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-<th style="text-align:left">New gene</th>
411
-<th style="text-align:center">BL tier</th>
412
-</tr>
413
-</thead>
414
-<tbody>
415
-<tr>
416
-<td style="text-align:left"><a href="../ARID1A">ARID1A</a></td>
417
-<td style="text-align:center">1</td>
418
-</tr>
419
-<tr>
420
-<td style="text-align:left"><a href="../GNA13">GNA13</a></td>
421
-<td style="text-align:center">1</td>
422
-</tr>
423
-<tr>
424
-<td style="text-align:left"><a href="../PTEN">PTEN</a></td>
425
-<td style="text-align:center">1</td>
426
-</tr>
427
-</tbody>
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-</table>
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-<h3 id="tier-2">Tier 2</h3>
430
-<table>
431
-<thead>
432
-<tr>
433
-<th style="text-align:left">New gene</th>
434
-<th style="text-align:center">BL tier</th>
435
-<th style="text-align:center">Rating of reviewed variants</th>
436
-</tr>
437
-</thead>
438
-<tbody>
439
-<tr>
440
-<td style="text-align:left"><a href="../ACAD9">ACAD9</a></td>
441
-<td style="text-align:center">2</td>
442
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
443
-</tr>
444
-<tr>
445
-<td style="text-align:left"><a href="../ACE">ACE</a></td>
446
-<td style="text-align:center">2</td>
447
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
448
-</tr>
449
-<tr>
450
-<td style="text-align:left"><a href="../ATP2C2">ATP2C2</a></td>
451
-<td style="text-align:center">2</td>
452
-<td style="text-align:center">★ ★ ☆ ☆ ☆</td>
453
-</tr>
454
-<tr>
455
-<td style="text-align:left"><a href="../BCL6">BCL6</a></td>
456
-<td style="text-align:center">2</td>
457
-<td style="text-align:center">★ ★ ★ ★ ☆</td>
458
-</tr>
459
-<tr>
460
-<td style="text-align:left"><a href="../BRAF">BRAF</a></td>
461
-<td style="text-align:center">2</td>
462
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
463
-</tr>
464
-<tr>
465
-<td style="text-align:left"><a href="../BRD4">BRD4</a></td>
466
-<td style="text-align:center">2</td>
467
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
468
-</tr>
469
-<tr>
470
-<td style="text-align:left"><a href="../BTG2">BTG2</a></td>
471
-<td style="text-align:center">2</td>
472
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
473
-</tr>
474
-<tr>
475
-<td style="text-align:left"><a href="../C6orf27">C6orf27</a></td>
476
-<td style="text-align:center">2</td>
477
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
478
-</tr>
479
-<tr>
480
-<td style="text-align:left"><a href="../CAD">CAD</a></td>
481
-<td style="text-align:center">2</td>
482
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
483
-</tr>
484
-<tr>
485
-<td style="text-align:left"><a href="../CARD4">CARD4</a></td>
486
-<td style="text-align:center">2</td>
487
-<td style="text-align:center">★ ★ ★ ★ ☆</td>
488
-</tr>
489
-<tr>
490
-<td style="text-align:left"><a href="../CCT6B">CCT6B</a></td>
491
-<td style="text-align:center">2</td>
492
-<td style="text-align:center"><em>Germline</em></td>
493
-</tr>
494
-<tr>
495
-<td style="text-align:left"><a href="../CDC73">CDC73</a></td>
496
-<td style="text-align:center">2</td>
497
-<td style="text-align:center">★ ★ ★ ☆ ☆</td>
498
-</tr>
499
-<tr>
500
-<td style="text-align:left"><a href="../CDH17">CDH17</a></td>
501
-<td style="text-align:center">2</td>
502
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
503
-</tr>
504
-<tr>
505
-<td style="text-align:left"><a href="../COL4A2">COL4A2</a></td>
506
-<td style="text-align:center">2</td>
507
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
508
-</tr>
509
-<tr>
510
-<td style="text-align:left"><a href="../CREBBP">CREBBP</a></td>
511
-<td style="text-align:center">2</td>
512
-<td style="text-align:center">★ ★ ★ ★ ☆</td>
513
-</tr>
514
-<tr>
515
-<td style="text-align:left"><a href="../CYB5D1">CYB5D1</a></td>
516
-<td style="text-align:center">2</td>
517
-<td style="text-align:center">★ ★ ☆ ☆ ☆</td>
518
-</tr>
519
-<tr>
520
-<td style="text-align:left"><a href="../CYP4F22">CYP4F22</a></td>
521
-<td style="text-align:center">2</td>
522
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
523
-</tr>
524
-<tr>
525
-<td style="text-align:left"><a href="../DLGAP1">DLGAP1</a></td>
526
-<td style="text-align:center">2</td>
527
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
528
-</tr>
529
-<tr>
530
-<td style="text-align:left"><a href="../DTX1">DTX1</a></td>
531
-<td style="text-align:center">2</td>
532
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
533
-</tr>
534
-<tr>
535
-<td style="text-align:left"><a href="../EIF2C4">EIF2C4</a></td>
536
-<td style="text-align:center">2</td>
537
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
538
-</tr>
539
-<tr>
540
-<td style="text-align:left"><a href="../EML2">EML2</a></td>
541
-<td style="text-align:center">2</td>
542
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
543
-</tr>
544
-<tr>
545
-<td style="text-align:left"><a href="../ENTPD3">ENTPD3</a></td>
546
-<td style="text-align:center">2</td>
547
-<td style="text-align:center">★ ★ ☆ ☆ ☆</td>
548
-</tr>
549
-<tr>
550
-<td style="text-align:left"><a href="../EPHB2">EPHB2</a></td>
551
-<td style="text-align:center">2</td>
552
-<td style="text-align:center"></td>
553
-</tr>
554
-<tr>
555
-<td style="text-align:left"><a href="../EZH2">EZH2</a></td>
556
-<td style="text-align:center">2</td>
557
-<td style="text-align:center">★ ★ ★ ★ ★</td>
558
-</tr>
559
-<tr>
560
-<td style="text-align:left"><a href="../FAM129B">FAM129B</a></td>
561
-<td style="text-align:center">2</td>
562
-<td style="text-align:center"></td>
563
-</tr>
564
-<tr>
565
-<td style="text-align:left"><a href="../FGFR3">FGFR3</a></td>
566
-<td style="text-align:center">2</td>
567
-<td style="text-align:center"></td>
568
-</tr>
569
-<tr>
570
-<td style="text-align:left"><a href="../FTCD">FTCD</a></td>
571
-<td style="text-align:center">2</td>
572
-<td style="text-align:center"></td>
573
-</tr>
574
-<tr>
575
-<td style="text-align:left"><a href="../GGTLA4">GGTLA4</a></td>
576
-<td style="text-align:center">2</td>
577
-<td style="text-align:center"></td>
578
-</tr>
579
-<tr>
580
-<td style="text-align:left"><a href="../GRIK5">GRIK5</a></td>
581
-<td style="text-align:center">2</td>
582
-<td style="text-align:center"></td>
583
-</tr>
584
-<tr>
585
-<td style="text-align:left"><a href="../ICK">ICK</a></td>
586
-<td style="text-align:center">2</td>
587
-<td style="text-align:center"></td>
588
-</tr>
589
-<tr>
590
-<td style="text-align:left"><a href="../ITPR3">ITPR3</a></td>
591
-<td style="text-align:center">2</td>
592
-<td style="text-align:center"></td>
593
-</tr>
594
-<tr>
595
-<td style="text-align:left"><a href="../KIFC3">KIFC3</a></td>
596
-<td style="text-align:center">2</td>
597
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
598
-</tr>
599
-<tr>
600
-<td style="text-align:left"><a href="../MAP3K6">MAP3K6</a></td>
601
-<td style="text-align:center">2</td>
602
-<td style="text-align:center"></td>
603
-</tr>
604
-<tr>
605
-<td style="text-align:left"><a href="../MYH10">MYH10</a></td>
606
-<td style="text-align:center">2</td>
607
-<td style="text-align:center"></td>
608
-</tr>
609
-<tr>
610
-<td style="text-align:left"><a href="../NBEAL1">NBEAL1</a></td>
611
-<td style="text-align:center">2</td>
612
-<td style="text-align:center"></td>
613
-</tr>
614
-<tr>
615
-<td style="text-align:left"><a href="../NOTCH1">NOTCH1</a></td>
616
-<td style="text-align:center">2</td>
617
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
618
-</tr>
619
-<tr>
620
-<td style="text-align:left"><a href="../NRXN2">NRXN2</a></td>
621
-<td style="text-align:center">2</td>
622
-<td style="text-align:center"></td>
623
-</tr>
624
-<tr>
625
-<td style="text-align:left"><a href="../P2RY2">P2RY2</a></td>
626
-<td style="text-align:center">2</td>
627
-<td style="text-align:center"></td>
628
-</tr>
629
-<tr>
630
-<td style="text-align:left"><a href="../PC">PC</a></td>
631
-<td style="text-align:center">2</td>
632
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
633
-</tr>
634
-<tr>
635
-<td style="text-align:left"><a href="../POLRMT">POLRMT</a></td>
636
-<td style="text-align:center">2</td>
637
-<td style="text-align:center"></td>
638
-</tr>
639
-<tr>
640
-<td style="text-align:left"><a href="../POR">POR</a></td>
641
-<td style="text-align:center">2</td>
642
-<td style="text-align:center"></td>
643
-</tr>
644
-<tr>
645
-<td style="text-align:left"><a href="../PRSS22">PRSS22</a></td>
646
-<td style="text-align:center">2</td>
647
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
648
-</tr>
649
-<tr>
650
-<td style="text-align:left"><a href="../PTPRN">PTPRN</a></td>
651
-<td style="text-align:center">2</td>
652
-<td style="text-align:center"></td>
653
-</tr>
654
-<tr>
655
-<td style="text-align:left"><a href="../RANBP6">RANBP6</a></td>
656
-<td style="text-align:center">2</td>
657
-<td style="text-align:center"></td>
658
-</tr>
659
-<tr>
660
-<td style="text-align:left"><a href="../RBP3">RBP3</a></td>
661
-<td style="text-align:center">2</td>
662
-<td style="text-align:center"></td>
663
-</tr>
664
-<tr>
665
-<td style="text-align:left"><a href="../RET">RET</a></td>
666
-<td style="text-align:center">2</td>
667
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
668
-</tr>
669
-<tr>
670
-<td style="text-align:left"><a href="../SALL3">SALL3</a></td>
671
-<td style="text-align:center">2</td>
672
-<td style="text-align:center"></td>
673
-</tr>
674
-<tr>
675
-<td style="text-align:left"><a href="../SAPS2">SAPS2</a></td>
676
-<td style="text-align:center">2</td>
677
-<td style="text-align:center"></td>
678
-</tr>
679
-<tr>
680
-<td style="text-align:left"><a href="../SBF1">SBF1</a></td>
681
-<td style="text-align:center">2</td>
682
-<td style="text-align:center"></td>
683
-</tr>
684
-<tr>
685
-<td style="text-align:left"><a href="../SF3B1">SF3B1</a></td>
686
-<td style="text-align:center">2</td>
687
-<td style="text-align:center"></td>
688
-</tr>
689
-<tr>
690
-<td style="text-align:left"><a href="../SHANK1">SHANK1</a></td>
691
-<td style="text-align:center">2</td>
692
-<td style="text-align:center"></td>
693
-</tr>
694
-<tr>
695
-<td style="text-align:left"><a href="../SLC29A2">SLC29A2</a></td>
696
-<td style="text-align:center">2</td>
697
-<td style="text-align:center"></td>
698
-</tr>
699
-<tr>
700
-<td style="text-align:left"><a href="../SYNGAP1">SYNGAP1</a></td>
701
-<td style="text-align:center">2</td>
702
-<td style="text-align:center">★ ☆ ☆ ☆ ☆</td>
703
-</tr>
704
-<tr>
705
-<td style="text-align:left"><a href="../TBC1D9B">TBC1D9B</a></td>
706
-<td style="text-align:center">2</td>
707
-<td style="text-align:center"></td>
708
-</tr>
709
-<tr>
710
-<td style="text-align:left"><a href="../TIGD6">TIGD6</a></td>
711
-<td style="text-align:center">2</td>
712
-<td style="text-align:center"></td>
713
-</tr>
714
-<tr>
715
-<td style="text-align:left"><a href="../TPST2">TPST2</a></td>
716
-<td style="text-align:center">2</td>
717
-<td style="text-align:center"></td>
718
-</tr>
719
-<tr>
720
-<td style="text-align:left"><a href="../ZNF229">ZNF229</a></td>
721
-<td style="text-align:center">2</td>
722
-<td style="text-align:center"><em>Germline</em></td>
723
-</tr>
724
-</tbody>
725
-</table>
726
-<h1 id="details">Details</h1>
727
-
728
-</body>
729
-</html>
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