HLA-DQA1.md
... ...
@@ -20,7 +20,7 @@ timeline
20 20
21 21
|Entity|Tier|Description |
22 22
|:------:|:----:|--------------------------|
23
-|![DLBCL](images/icons/DLBCL_tier1.png) |1 |high-confidence DLBCL gene[@hubschmannMutationalMechanismsShaping2021b]|
23
+|![DLBCL](images/icons/DLBCL_tier1.png) |1 |high-confidence DLBCL gene[@hubschmannMutationalMechanismsShaping2021]|
24 24
25 25
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
26 26
HLA-DQB1.md
... ...
@@ -17,7 +17,7 @@ timeline
17 17
18 18
|Entity|Tier|Description |
19 19
|:------:|:----:|--------------------------------------|
20
-|![BL](images/icons/BL_tier2.png) |2 |relevance in BL not firmly established[@burkhardtClinicalRelevanceMolecular2022b]|
20
+|![BL](images/icons/BL_tier2.png) |2 |relevance in BL not firmly established[@burkhardtClinicalRelevanceMolecular2022]|
21 21
22 22
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
23 23
HRNR.md
... ...
@@ -20,7 +20,7 @@ timeline
20 20
21 21
|Entity|Tier|Description|
22 22
|:------:|:----:|--------------------------------------|
23
-|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@dunsCharacterizationDLBCLPMBL2021b]|
23
+|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@dunsCharacterizationDLBCLPMBL2021]|
24 24
25 25
26 26
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
HVCN1.md
... ...
@@ -21,7 +21,7 @@ timeline
21 21
|Entity|Tier|Description |
22 22
|:------:|:----:|--------------------------------------|
23 23
|![DLBCL](images/icons/DLBCL_tier1.png) |1 |high-confidence DLBCL gene |
24
-|![FL](images/icons/FL_tier1.png) |1 |high-confidence FL gene [@krysiakRecurrentSomaticMutations2017b]|
24
+|![FL](images/icons/FL_tier1.png) |1 |high-confidence FL gene [@krysiakRecurrentSomaticMutations2017]|
25 25
26 26
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
27 27
ID3.md
... ...
@@ -6,8 +6,8 @@ link-citations: true
6 6
# ID3
7 7
8 8
## History
9
-ID3 was first reported as mutated in BL in 2012 by Richter et al.[@richterRecurrentMutationID32012a]
10
-The existence of mutations in DLBCL were described in 2012 by Schmitz et al[@schmitzBurkittLymphomaPathogenesis2012] and later in MZL by Spina et al.[@spinaGeneticsNodalMarginal2016b]
9
+ID3 was first reported as mutated in BL in 2012 by Richter et al.[@richterRecurrentMutationID32012]
10
+The existence of mutations in DLBCL were described in 2012 by Schmitz et al[@schmitzBurkittLymphomaPathogenesis2012] and later in MZL by Spina et al.[@spinaGeneticsNodalMarginal2016]
11 11
12 12
```mermaid
13 13
%%{init: { 'logLevel': 'debug', 'theme': 'dark' } }%%
IGLL5.md
... ...
@@ -22,7 +22,7 @@ timeline
22 22
|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@deschGenotypingCirculatingTumor2020]|
23 23
|![BL](images/icons/BL_tier2.png) |2-a | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@paneaWholeGenomeLandscape2019]|
24 24
|![DLBCL](images/icons/DLBCL_tier2.png) |2-a | aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous |
25
-|![FL](images/icons/FL_tier2.png) |2-a | aSHM target; Although recurrent, the relevance of mutations in FL is tenuous [@russler-germainMutationsAssociatedProgression2023b]|
25
+|![FL](images/icons/FL_tier2.png) |2-a | aSHM target; Although recurrent, the relevance of mutations in FL is tenuous [@russler-germainMutationsAssociatedProgression2023]|
26 26
27 27
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
28 28
IKBKB.md
... ...
@@ -19,8 +19,8 @@ timeline
19 19
20 20
|Entity|Tier|Description |
21 21
|:------:|:----:|-----------------------------------------|
22
-|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@wienandGenomicAnalysesFlowsorted2019b]|
23
-|![MZL](images/icons/MZL_tier2.png)|2|relevance in MZL not firmly established[@rossiAlterationBIRC3Multiple2011a]|
22
+|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@wienandGenomicAnalysesFlowsorted2019]|
23
+|![MZL](images/icons/MZL_tier2.png)|2|relevance in MZL not firmly established[@rossiAlterationBIRC3Multiple2011]|
24 24
|![DLBCL](images/icons/DLBCL_tier2.png) |2 |relevance in DLBCL not firmly established[@reddyGeneticFunctionalDrivers2017]|
25 25
26 26
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
IKBKE.md
... ...
@@ -19,7 +19,7 @@ timeline
19 19
20 20
|Entity|Tier|Description |
21 21
|:------:|:----:|-----------------------------------------|
22
-|![DLBCL](images/icons/DLBCL_tier2.png) |2 |relevance in DLBCL not firmly established[@hubschmannMutationalMechanismsShaping2021b]|
22
+|![DLBCL](images/icons/DLBCL_tier2.png) |2 |relevance in DLBCL not firmly established[@hubschmannMutationalMechanismsShaping2021]|
23 23
24 24
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
25 25
IL13RA1.md
... ...
@@ -20,7 +20,7 @@ timeline
20 20
21 21
|Entity|Tier|Description|
22 22
|:------:|:----:|--------------------------------------|
23
-|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@mottokIntegrativeGenomicAnalysis2019b]|
23
+|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@mottokIntegrativeGenomicAnalysis2019]|
24 24
25 25
26 26
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
IL1RAPL2.md
... ...
@@ -20,7 +20,7 @@ timeline
20 20
21 21
|Entity|Tier|Description|
22 22
|:------:|:----:|--------------------------------------|
23
-|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@mottokIntegrativeGenomicAnalysis2019b]|
23
+|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@mottokIntegrativeGenomicAnalysis2019]|
24 24
25 25
26 26
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
IL4R.md
... ...
@@ -21,8 +21,8 @@ timeline
21 21
22 22
|Entity|Tier|Description |
23 23
|:------:|:----:|--------------------------|
24
-|![PMBL](images/icons/PMBL_tier1.png)|1|high-confidence PMBL/cHL/GZL gene[@viganoSomaticIL4RMutations2018b]|
25
-|![DLBCL](images/icons/DLBCL_tier1.png) |1-a | aSHM target and high-confidence DLBCL gene[@dunsCharacterizationDLBCLPMBL2021b]|
24
+|![PMBL](images/icons/PMBL_tier1.png)|1|high-confidence PMBL/cHL/GZL gene[@viganoSomaticIL4RMutations2018]|
25
+|![DLBCL](images/icons/DLBCL_tier1.png) |1-a | aSHM target and high-confidence DLBCL gene[@dunsCharacterizationDLBCLPMBL2021]|
26 26
27 27
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
28 28
IL6.md
... ...
@@ -17,7 +17,7 @@ timeline
17 17
18 18
|Entity|Tier|Description |
19 19
|:------:|:----:|-----------------------------------------|
20
-|![DLBCL](images/icons/DLBCL_tier2.png) |2 |relevance in DLBCL not firmly established[@chapuyMolecularSubtypesDiffuse2018b]|
20
+|![DLBCL](images/icons/DLBCL_tier2.png) |2 |relevance in DLBCL not firmly established[@chapuyMolecularSubtypesDiffuse2018]|
21 21
22 22
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
23 23
IRF1.md
... ...
@@ -19,7 +19,7 @@ timeline
19 19
20 20
|Entity|Tier|Description |
21 21
|:------:|:----:|-----------------------------------------|
22
-|![DLBCL](images/icons/DLBCL_tier2.png) |2-a | aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous [@hubschmannMutationalMechanismsShaping2021b]|
22
+|![DLBCL](images/icons/DLBCL_tier2.png) |2-a | aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous [@hubschmannMutationalMechanismsShaping2021]|
23 23
24 24
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
25 25
IRF2BP2.md
... ...
@@ -20,7 +20,7 @@ timeline
20 20
21 21
|Entity|Tier|Description|
22 22
|:------:|:----:|--------------------------------------|
23
-|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@mottokIntegrativeGenomicAnalysis2019b]|
23
+|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@mottokIntegrativeGenomicAnalysis2019]|
24 24
25 25
26 26
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
IRF4.md
... ...
@@ -24,7 +24,7 @@ timeline
24 24
25 25
|Entity|Tier|Description |
26 26
|:------:|:----:|--------------------------|
27
-|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@mottokIntegrativeGenomicAnalysis2019b]|
27
+|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@mottokIntegrativeGenomicAnalysis2019]|
28 28
|![DLBCL](images/icons/DLBCL_tier1.png) |1-a | aSHM target and high-confidence DLBCL gene[@morinFrequentMutationHistonemodifying2011]|
29 29
|![FL](images/icons/FL_tier1.png) |1-a | aSHM target and high-confidence FL gene |
30 30
IRF8.md
... ...
@@ -26,7 +26,7 @@ timeline
26 26
27 27
|Entity|Tier|Description |
28 28
|:------:|:----:|--------------------------------------|
29
-|![PMBL](images/icons/PMBL_tier1.png)|1|high-confidence PMBL/cHL/GZL gene[@mottokIntegrativeGenomicAnalysis2019b]|
29
+|![PMBL](images/icons/PMBL_tier1.png)|1|high-confidence PMBL/cHL/GZL gene[@mottokIntegrativeGenomicAnalysis2019]|
30 30
|![BL](images/icons/BL_tier2.png) |2-a | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@paneaWholeGenomeLandscape2019]|
31 31
|![DLBCL](images/icons/DLBCL_tier1.png) |1-a | aSHM target and high-confidence DLBCL gene [@morinFrequentMutationHistonemodifying2011]|
32 32
|![FL](images/icons/FL_tier1.png) |1-a | aSHM target and high-confidence FL gene [@morinFrequentMutationHistonemodifying2011]|
ITPKB.md
... ...
@@ -21,8 +21,8 @@ timeline
21 21
22 22
|Entity|Tier|Description |
23 23
|:------:|:----:|--------------------------|
24
-|![PMBL](images/icons/PMBL_tier1.png)|1|high-confidence PMBL/cHL/GZL gene[@reichelFlowSortingExome2015a]|
25
-|![DLBCL](images/icons/DLBCL_tier1.png) |1-a | aSHM target and high-confidence DLBCL gene[@schmitzGeneticsPathogenesisDiffuse2018a]|
24
+|![PMBL](images/icons/PMBL_tier1.png)|1|high-confidence PMBL/cHL/GZL gene[@reichelFlowSortingExome2015]|
25
+|![DLBCL](images/icons/DLBCL_tier1.png) |1-a | aSHM target and high-confidence DLBCL gene[@schmitzGeneticsPathogenesisDiffuse2018]|
26 26
|![FL](images/icons/FL_tier1.png) |1-a | aSHM target and high-confidence FL gene |
27 27
28 28
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
ITPR3.md
... ...
@@ -20,7 +20,7 @@ timeline
20 20
21 21
|Entity|Tier|Description |
22 22
|:------:|:----:|--------------------------------------|
23
-|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@tiacciPervasiveMutationsJAKSTAT2018b]|
23
+|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@tiacciPervasiveMutationsJAKSTAT2018]|
24 24
|![BL](images/icons/BL_tier2.png) |3 |Retired, Failed QC[@loveGeneticLandscapeMutations2012]|
25 25
26 26
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
JAK1.md
... ...
@@ -21,7 +21,7 @@ timeline
21 21
22 22
|Entity|Tier|Description |
23 23
|:------:|:----:|-----------------------------------------|
24
-|![PMBL](images/icons/PMBL_tier1.png)|1|high-confidence PMBL/cHL/GZL gene[@mottokIntegrativeGenomicAnalysis2019b]|
24
+|![PMBL](images/icons/PMBL_tier1.png)|1|high-confidence PMBL/cHL/GZL gene[@mottokIntegrativeGenomicAnalysis2019]|
25 25
|![DLBCL](images/icons/DLBCL_tier2.png) |2 |relevance in DLBCL not firmly established[@zhangGeneticHeterogeneityDiffuse2013]|
26 26
27 27
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
JUNB.md
... ...
@@ -23,7 +23,7 @@ timeline
23 23
24 24
|Entity|Tier|Description |
25 25
|:------:|:----:|--------------------------|
26
-|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@mottokIntegrativeGenomicAnalysis2019b]|
26
+|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@mottokIntegrativeGenomicAnalysis2019]|
27 27
|![DLBCL](images/icons/DLBCL_tier1.png) |1 |high-confidence DLBCL gene[@reddyGeneticFunctionalDrivers2017; @hubschmannMutationalMechanismsShaping2021b]|
28 28
29 29
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
JUP.md
... ...
@@ -19,7 +19,7 @@ timeline
19 19
20 20
|Entity|Tier|Description |
21 21
|:------:|:----:|--------------------------------------|
22
-|![FL](images/icons/FL_tier2.png) |2 |relevance in FL not firmly established[@hubschmannMutationalMechanismsShaping2021b]|
22
+|![FL](images/icons/FL_tier2.png) |2 |relevance in FL not firmly established[@hubschmannMutationalMechanismsShaping2021]|
23 23
24 24
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
25 25
KIR3DL1.md
... ...
@@ -17,7 +17,7 @@ timeline
17 17
18 18
|Entity|Tier|Description |
19 19
|:------:|:----:|--------------------------------------|
20
-|![FL](images/icons/FL_tier2.png) |2 |relevance in FL not firmly established[@russler-germainMutationsAssociatedProgression2023b]|
20
+|![FL](images/icons/FL_tier2.png) |2 |relevance in FL not firmly established[@russler-germainMutationsAssociatedProgression2023]|
21 21
22 22
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
23 23
KLHL14.md
... ...
@@ -22,7 +22,7 @@ timeline
22 22
23 23
|Entity|Tier|Description |
24 24
|:------:|:----:|--------------------------|
25
-|![DLBCL](images/icons/DLBCL_tier1.png) |1 |high-confidence DLBCL gene[@zhangGeneticHeterogeneityDiffuse2013; @reddyGeneticFunctionalDrivers2017; @schmitzGeneticsPathogenesisDiffuse2018a]|
25
+|![DLBCL](images/icons/DLBCL_tier1.png) |1 |high-confidence DLBCL gene[@zhangGeneticHeterogeneityDiffuse2013; @reddyGeneticFunctionalDrivers2017; @schmitzGeneticsPathogenesisDiffuse2018]|
26 26
27 27
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
28 28
KLHL21.md
... ...
@@ -54,8 +54,8 @@ View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/K
54 54
55 55
## KLHL21 Expression
56 56
![](images/gene_expression/KLHL21_by_pathology.svg)
57
-<!-- ORIGIN: schmitzGeneticsPathogenesisDiffuse2018a -->
58
-<!-- DLBCL: schmitzGeneticsPathogenesisDiffuse2018a -->
57
+<!-- ORIGIN: schmitzGeneticsPathogenesisDiffuse2018 -->
58
+<!-- DLBCL: schmitzGeneticsPathogenesisDiffuse2018 -->
59 59
60 60
## References
61 61
KLHL26.md
... ...
@@ -17,7 +17,7 @@ timeline
17 17
18 18
|Entity|Tier|Description |
19 19
|:------:|:----:|--------------------------------------|
20
-|![BL](images/icons/BL_tier2.png) |2 |relevance in BL not firmly established[@burkhardtClinicalRelevanceMolecular2022b]|
20
+|![BL](images/icons/BL_tier2.png) |2 |relevance in BL not firmly established[@burkhardtClinicalRelevanceMolecular2022]|
21 21
22 22
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
23 23
... ...
@@ -48,7 +48,7 @@ View all variants in GenomePaint [hg19](https://morinlab.github.io/LLMPP/GAMBL/K
48 48
49 49
## KLHL26 Expression
50 50
![](images/gene_expression/KLHL26_by_pathology.svg)
51
-<!-- ORIGIN: burkhardtClinicalRelevanceMolecular2022b -->
52
-<!-- BL: burkhardtClinicalRelevanceMolecular2022b -->
51
+<!-- ORIGIN: burkhardtClinicalRelevanceMolecular2022 -->
52
+<!-- BL: burkhardtClinicalRelevanceMolecular2022 -->
53 53
54 54
## References
KMT2C.md
... ...
@@ -25,7 +25,7 @@ timeline
25 25
26 26
|Entity|Tier|Description |
27 27
|:------:|:----:|---------------------------------------|
28
-|![PMBL](images/icons/PMBL_tier1.png)|1|high-confidence PMBL/cHL/GZL gene[@sarkozyMutationalLandscapeGray2021a]|
28
+|![PMBL](images/icons/PMBL_tier1.png)|1|high-confidence PMBL/cHL/GZL gene[@sarkozyMutationalLandscapeGray2021]|
29 29
|![BL](images/icons/BL_tier2.png) |2 |relevance in BL not firmly established [@zhouSporadicEndemicBurkitt2019]|
30 30
|![DLBCL](images/icons/DLBCL_tier1.png) |1 |high-confidence DLBCL gene [@zhangGeneticHeterogeneityDiffuse2013; @reddyGeneticFunctionalDrivers2017]|
31 31
|![MCL](images/icons/MCL_tier2.png) |2 |relevance in MCL not firmly established[@zhangGenomicLandscapeMantle2014]|
KMT2D.md
... ...
@@ -30,7 +30,7 @@ timeline
30 30
31 31
|Entity|Tier|Description |
32 32
|:------:|:----:|--------------------------|
33
-|![MZL](images/icons/MZL_tier1.png)|1|high-confidence MZL gene[@rossiCodingGenomeSplenic2012c]|
33
+|![MZL](images/icons/MZL_tier1.png)|1|high-confidence MZL gene[@rossiCodingGenomeSplenic2012]|
34 34
|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@deschGenotypingCirculatingTumor2020]|
35 35
|![FL](images/icons/FL_tier1.png) |1 |high-confidence FL gene [@morinFrequentMutationHistonemodifying2011]|
36 36
|![DLBCL](images/icons/DLBCL_tier1.png) |1 |high-confidence DLBCL gene[@morinFrequentMutationHistonemodifying2011]|
KRAS.md
... ...
@@ -20,7 +20,7 @@ timeline
20 20
21 21
|Entity|Tier|Description |
22 22
|:------:|:----:|--------------------------|
23
-|![DLBCL](images/icons/DLBCL_tier1.png) |1 |high-confidence DLBCL gene[@lohrDiscoveryPrioritizationSomatic2012a]|
23
+|![DLBCL](images/icons/DLBCL_tier1.png) |1 |high-confidence DLBCL gene[@lohrDiscoveryPrioritizationSomatic2012]|
24 24
25 25
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
26 26
KRTAP5-5.md
... ...
@@ -20,7 +20,7 @@ timeline
20 20
21 21
|Entity|Tier|Description|
22 22
|:------:|:----:|--------------------------------------|
23
-|![DLBCL](images/icons/DLBCL_tier2.png)|2|relevance in DLBCL not firmly established[@lohrDiscoveryPrioritizationSomatic2012a]|
23
+|![DLBCL](images/icons/DLBCL_tier2.png)|2|relevance in DLBCL not firmly established[@lohrDiscoveryPrioritizationSomatic2012]|
24 24
25 25
26 26
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
LAMA5.md
... ...
@@ -17,7 +17,7 @@ timeline
17 17
18 18
|Entity|Tier|Description |
19 19
|:------:|:----:|-----------------------------------------|
20
-|![DLBCL](images/icons/DLBCL_tier2.png) |2 |relevance in DLBCL not firmly established[@schmitzGeneticsPathogenesisDiffuse2018a]|
20
+|![DLBCL](images/icons/DLBCL_tier2.png) |2 |relevance in DLBCL not firmly established[@schmitzGeneticsPathogenesisDiffuse2018]|
21 21
22 22
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
23 23
LAPTM5.md
... ...
@@ -20,7 +20,7 @@ timeline
20 20
|Entity|Tier|Description |
21 21
|:------:|:----:|-----------------------------------------|
22 22
|![DLBCL](images/icons/DLBCL_tier2.png) |2-a | aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous |
23
-|![FL](images/icons/FL_tier2.png) |2-a | aSHM target; Although recurrent, the relevance of mutations in FL is tenuous [@hubschmannMutationalMechanismsShaping2021b]|
23
+|![FL](images/icons/FL_tier2.png) |2-a | aSHM target; Although recurrent, the relevance of mutations in FL is tenuous [@hubschmannMutationalMechanismsShaping2021]|
24 24
25 25
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
26 26
LPHN3.md
... ...
@@ -20,7 +20,7 @@ timeline
20 20
21 21
|Entity|Tier|Description|
22 22
|:------:|:----:|--------------------------------------|
23
-|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@dunsCharacterizationDLBCLPMBL2021b]|
23
+|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@dunsCharacterizationDLBCLPMBL2021]|
24 24
25 25
26 26
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
LPP.md
... ...
@@ -18,7 +18,7 @@ timeline
18 18
19 19
|Entity|Tier|Description |
20 20
|:------:|:----:|-----------------------------------------|
21
-|![DLBCL](images/icons/DLBCL_tier2.png) |2-a | aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous [@arthurGenomewideDiscoverySomatic2018]|
21
+|![DLBCL](images/icons/DLBCL_tier2.png) |2 | aSHM target; Although recurrent, the relevance of mutations in DLBCL is tenuous [@arthurGenomewideDiscoverySomatic2018]|
22 22
23 23
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
24 24
LRP12.md
... ...
@@ -19,7 +19,7 @@ timeline
19 19
20 20
|Entity|Tier|Description |
21 21
|:------:|:----:|-----------------------------------------|
22
-|![DLBCL](images/icons/DLBCL_tier2.png) |2 |relevance in DLBCL not firmly established[@hubschmannMutationalMechanismsShaping2021b]|
22
+|![DLBCL](images/icons/DLBCL_tier2.png) |2 |relevance in DLBCL not firmly established[@hubschmannMutationalMechanismsShaping2021]|
23 23
24 24
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
25 25
LRP1B.md
... ...
@@ -21,7 +21,7 @@ timeline
21 21
22 22
|Entity|Tier|Description|
23 23
|:------:|:----:|--------------------------------------|
24
-|![MZL](images/icons/MZL_tier2.png)|2|relevance in MZL not firmly established[@spinaGeneticsNodalMarginal2016b]|
24
+|![MZL](images/icons/MZL_tier2.png)|2|relevance in MZL not firmly established[@spinaGeneticsNodalMarginal2016]|
25 25
26 26
27 27
## Mutation incidence in large patient cohorts (GAMBL reanalysis)
LRRN3.md
... ...
@@ -19,7 +19,7 @@ timeline
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|Entity|Tier|Description |
21 21
|:------:|:----:|-----------------------------------------|
22
-|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@sarkozyMutationalLandscapeGray2021a]|
22
+|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@sarkozyMutationalLandscapeGray2021]|
23 23
|![DLBCL](images/icons/DLBCL_tier1.png) |1 |High-confidence DLBCL gene [@zhangGeneticHeterogeneityDiffuse2013; @morinMutationalStructuralAnalysis2013]|
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## Mutation incidence in large patient cohorts (GAMBL reanalysis)
LTB.md
... ...
@@ -22,7 +22,7 @@ timeline
22 22
|Entity|Tier|Description |
23 23
|:------:|:----:|--------------------------------------|
24 24
|![PMBL](images/icons/PMBL_tier1.png)|1|high-confidence PMBL/cHL/GZL gene[@deschGenotypingCirculatingTumor2020]|
25
-|![DLBCL](images/icons/DLBCL_tier1.png) |1-a | aSHM target and high-confidence DLBCL gene [@chapuyMolecularSubtypesDiffuse2018b]|
25
+|![DLBCL](images/icons/DLBCL_tier1.png) |1-a | aSHM target and high-confidence DLBCL gene [@chapuyMolecularSubtypesDiffuse2018]|
26 26
|![FL](images/icons/FL_tier1.png) |1-a | aSHM target and high-confidence FL gene |
27 27
|![BL](images/icons/BL_tier2.png) |2-a | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@paneaWholeGenomeLandscape2019]|
28 28
LYN.md
... ...
@@ -19,7 +19,7 @@ timeline
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|Entity|Tier|Description |
21 21
|:------:|:----:|--------------------------|
22
-|![DLBCL](images/icons/DLBCL_tier1.png) |2 |low-confidence DLBCL gene[@chapuyMolecularSubtypesDiffuse2018b]|
22
+|![DLBCL](images/icons/DLBCL_tier1.png) |2 |low-confidence DLBCL gene[@chapuyMolecularSubtypesDiffuse2018]|
23 23
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## Mutation incidence in large patient cohorts (GAMBL reanalysis)
25 25
MAGEC1.md
... ...
@@ -17,7 +17,7 @@ timeline
17 17
18 18
|Entity|Tier|Description |
19 19
|:------:|:----:|--------------------------------------|
20
-|![FL](images/icons/FL_tier2.png) |2 |relevance in FL not firmly established[@russler-germainMutationsAssociatedProgression2023b]|
20
+|![FL](images/icons/FL_tier2.png) |2 |relevance in FL not firmly established[@russler-germainMutationsAssociatedProgression2023]|
21 21
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## Mutation incidence in large patient cohorts (GAMBL reanalysis)
23 23
MAGEC2.md
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@@ -20,7 +20,7 @@ timeline
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21 21
|Entity|Tier|Description|
22 22
|:------:|:----:|--------------------------------------|
23
-|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@mottokIntegrativeGenomicAnalysis2019b]|
23
+|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@mottokIntegrativeGenomicAnalysis2019]|
24 24
25 25
26 26
## Mutation incidence in large patient cohorts (GAMBL reanalysis)